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  • Oxford University Press  (13)
  • American Association for the Advancement of Science (AAAS)  (6)
  • Blackwell Publishing Ltd  (5)
  • Nature Publishing Group
  • 2000-2004  (28)
  • 1960-1964
  • 2004  (28)
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  • 2000-2004  (28)
  • 1960-1964
Year
  • 1
    Electronic Resource
    Electronic Resource
    Approximating the degrees of freedom for contrasts of genotypes laid out as subplots in an alpha-design in a split-plot experiment (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Plant breeding 123 (2004), S. 0 
    Details
    ISSN: 1439-0523
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Alpha-designs have become popular in cultivar trials. Analysis is based on a mixed model. As a result of imbalance, inference tests require approximate methods. This paper investigates the Type I error control of different Satterthwaite approximations for the denominator degrees of freedom of Wald-type F-tests and t-tests in a two-factorial alpha-design with cultivars as the subplot factor and management intensities (fertilization, plant protection) as the main plot factor. Simulation results demonstrate good error control for cultivar comparison at the same intensity, with the need for an approximation which diminishes as the number of cultivars increases. By contrast, a comparison of intensities entails a more substantial departure from the nominal significance level, and this is not entirely offset by any of the approximations. The methods are demonstrated using two real data sets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1439-0523.2003.00964.x
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  • 2
    Electronic Resource
    Electronic Resource
    Managing Partnerships with State-Owned Joint Venture Companies: Experiences from Vietnam (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Business strategy review 15 (2004), S. 0 
    Details
    ISSN: 1467-8616
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0955-6419.2004.00299.x
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  • 3
    Electronic Resource
    Electronic Resource
    Do Pharmaceuticals, Pathogens, and Other Organic Waste Water Compounds Persist When Waste Water Is Used for Recharge? (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water monitoring & remediation 24 (2004), S. 0 
    Details
    ISSN: 1745-6592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: A proof-of-concept experiment was devised to determine if pharmaceuticals and other organic waste water compounds (OWCs), as well as pathogens, found in treated effluent could be transported through a 2.4 m soil column and, thus, potentially reach ground water under recharge conditions similar to those in arid or semiarid climates. Treated effluent was applied at the top of the 2.4 m long, 32.5 cm diameter soil column over 23 days. Samples of the column inflow were collected from the effluent storage tank at the beginning (Tbegin) and end (Tend) of the experiment, and a sample of the soil column drainage at the base of the column (Bend) was collected at the end of the experiment. Samples were analyzed for 131 OWCs including veterinary and human antibiotics, other prescription and nonprescription drugs, widely used household and industrial chemicals, and steroids and reproductive hormones, as well as the pathogens Salmonella and Legionella. Analytical results for the two effluent samples taken at the beginning (Tbegin) and end (Tend) of the experiment indicate that the number of OWCs detected in the column inflow decreased by 25% (eight compounds) and the total concentration of OWCs decreased by 46% while the effluent was in the storage tank during the 23-day experiment. After percolating through the soil column, an additional 18 compounds detected in Tend (67% of OWCs) were no longer detected in the effluent (Bend) and the total concentration of OWCs decreased by more than 70%. These compounds may have been subject to transformation (biotic and abiotic), adsorption, and (or) volatilization in the storage tank and during travel through the soil column. Eight compounds—carbamazapine; sulfamethoxazole; benzophenone; 5-methyl-1H-benzotriazole; N, N-diethyltoluamide; tributylphosphate; tri(2-chloroethyl) phosphate; and cholesterol—were detected in all three samples indicating they have the potential to reach ground water under recharge conditions similar to those in arid and semiarid climates. Results from real-time polymerase chain reactions demonstrated the presence of Legionella in all three samples. Salmonella was detected only in Tbegin, suggesting that the bacteria died off in the effluent storage tank over the period of the experiment. This proof-of-concept experiment demonstrates that, under recharge conditions similar to those in arid or semiarid climates, some pharmaceuticals, pathogens, and other OWCs can persist in treated effluent after soil-aquifer treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6592.2004.tb00713.x
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  • 4
    Electronic Resource
    Electronic Resource
    Pharmaceuticals and Other Organic Waste Water Contaminants Within a Leachate Plume Downgradient of a Municipal Landfill (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Ground water monitoring & remediation 24 (2004), S. 0 
    Details
    ISSN: 1745-6592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: Ground water samples collected from the Norman Landfill research site in central Oklahoma were analyzed as part of the U.S. Geological Survey (USGS) Toxic Substances Hydrology Program's national reconnaissance of pharmaceuticals and other organic waste water contaminants (OWCs) in ground water. Five sites, four of which are located downgradient of the landfill, were sampled in 2000 and analyzed for 76 OWCs using four research methods developed by the USGS. OWCs were detected in water samples from all of the sites sampled, with 22 of the 76 OWCs being detected at least once. Cholesterol (a plant and animal steroid), was detected at all five sites and was the only compound detected in a well upgradient of the landfill. N,N-diethyltoluamide (DEBT used in insect repellent) and tri(2-chloroethyl) phosphate (fire-retardant) were detected in water samples from all four sites located within the landfill-derived leachate plume. The sites closest to the landfill had more detections and greater concentrations of each of the detected compounds than sites located farther away. Detection of multiple OWCs occurred in the four sites located within the leachate plume, with a minimum of four and a maximum of 17 OWCs detected. Because the landfill was established in the 1920s and closed in 1985, many compounds detected in the leachate plume were likely disposed of decades ago. These results indicate the potential for long-term persistence and transport of some OWCs in ground water.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-6592.2004.tb00720.x
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  • 5
    Electronic Resource
    Electronic Resource
    Effect of Extraction pH and Temperature on Isoflavone and Saponin Partitioning and Profile During Soy Protein Isolate Production (2004)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 69 (2004), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: : Soy protein isolates (SPIs) are produced industrially using methods using various protein extraction temperatures and pH values. The effects of process temperature (25°C or 60°C) and pH (8.5, 9.5, or 10.5) on isoflavone and group B saponin extraction, partitioning, and profile during bench-scale SPI production were evaluated. Protein, isoflavone, and saponin extraction increased with increasing temperature and pH. Substantial quantities of isoflavones and saponins remained in the insoluble fraction waste stream. Isoflavones were also lost to the whey waste stream, whereas saponins were not detected in the whey. Neutralization of SPI samples at the time of analytical extraction increased measured isoflavone concentrations for the pH 8.5 process extraction treatments, whereas neutralization substantially increased measured saponin concentrations in SPIs for all process extraction treatments. Malonylglucoside isoflavones were primarily converted to β-glucoside forms as temperature and pH were increased, and these conditions caused conversion of αg, βg, and βa saponins to saponin V, I, and II forms, respectively. Analytical extraction pH should receive careful consideration when analyzing soy matrices for isoflavones and saponins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2004.tb09910.x
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  • 6
    Electronic Resource
    Electronic Resource
    Pam16 has an essential role in the mitochondrial protein import motor (2004)
    [s.l.] : Nature Publishing Group
    Nature structural & molecular biology 11 (2004), S. 226-233 
    Details
    ISSN: 1545-9985
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Mitochondrial preproteins destined for the matrix are translocated by two channel-forming transport machineries, the translocase of the outer membrane and the presequence translocase of the inner membrane. The presequence translocase-associated protein import motor (PAM) contains four essential ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nsmb735
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  • 7
    Electronic Resource
    Electronic Resource
    Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid (2004)
    [s.l.] : Nature Publishing Group
    Nature genetics 36 (2004), S. 1268-1274 
    Details
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Salmonella enterica serovars often have a broad host range, and some cause both gastrointestinal and systemic disease. But the serovars Paratyphi A and Typhi are restricted to humans and cause only systemic disease. It has been estimated that Typhi arose in the last few thousand years. The ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/ng1470
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  • 8
    Electronic Resource
    Electronic Resource
    Probing the precision of the mitotic clock with a live-cell fluorescent biosensor (2004)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 22 (2004), S. 306-312 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Precise timing of mitosis is essential for high-fidelity cell duplication. However, temporal measurements of the mitotic clock have been challenging. Here we present a fluorescent mitosis biosensor that monitors the time between nuclear envelope breakdown (NEB) and re-formation using parallel total ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt941
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  • 9
    Electronic Resource
    Electronic Resource
    Learning from the Altmeister (2004)
    [s.l.] : Nature Publishing Group
    Nature 428 (2004), S. 897-897 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...As an evolutionary biologist, I am trying to gain a better understanding of how diversity — at the level of both genes and organisms — arises. Specifically, I am a molecular evolutionary biologist, I collect and analyse DNA sequences and complete genomes. But my main passion is ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/428897a
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  • 10
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    Recruitment and spreading of the C. elegans dosage compensation complex along X chromosomes (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-02-21
    Description: To achieve X-chromosome dosage compensation, organisms must distinguish X chromosomes from autosomes. We identified multiple, cis-acting regions that recruit the Caenorhabditis elegans dosage compensation complex (DCC) through a search for regions of X that bind the complex when detached from X. The DCC normally assembles along the entire X chromosome, but not all detached regions recruit the complex, despite having genes known to be dosage compensated on the native X. Thus, the DCC binds first to recruitment sites, then spreads to neighboring X regions to accomplish chromosome-wide gene repression. From a large chromosomal domain, we defined a 793-base pair fragment that functions in vivo as an X-recognition element to recruit the DCC.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Csankovszki, Gyorgyi -- McDonel, Patrick -- Meyer, Barbara J -- F32-GM065007/GM/NIGMS NIH HHS/ -- R37-GM30702/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2004 Feb 20;303(5661):1182-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute and Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3204, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14976312" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Genetically Modified ; Base Sequence ; Binding Sites ; Caenorhabditis elegans/*genetics/metabolism ; Caenorhabditis elegans Proteins/*metabolism ; Carrier Proteins/metabolism ; Chromosomes/metabolism ; Cosmids ; DNA-Binding Proteins/metabolism ; Disorders of Sex Development ; *Dosage Compensation, Genetic ; Female ; In Situ Hybridization, Fluorescence ; Male ; Models, Genetic ; Molecular Sequence Data ; Nuclear Proteins/metabolism ; Repetitive Sequences, Nucleic Acid ; X Chromosome/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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