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  • GeoForschungsZentrum Potsdam  (1)
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  • Elsevier
  • 2015-2019
  • 2000-2004  (2)
  • 2001  (2)
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  • 1
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    GeoForschungsZentrum Potsdam
    In:  In: Klimaweißbuch : Klimainformationen aus geowissenschaftlicher Forschung (Fallstudien) ; Stand und notwendige Erfordernisse der Paläoklimaforschung. , ed. by Negendank, J. F. W. Terra Nostra (2001,7). GeoForschungsZentrum Potsdam, Potsdam, pp. 71-77.
    Publikationsdatum: 2014-07-23
    Materialart: Book chapter , NonPeerReviewed
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Publikationsdatum: 2018-01-25
    Beschreibung: The aim of this study was the documentation of the molecular immune response of Suberites domuncula upon bacterial infection. Additionally, the bacteria that are naturally present in the sponge after prolonged aquarium maintenance were characterized. After 6 months of maintenance of S. domuncula in seawater aquaria, only one bacterial 16S rDNA sequence could be recovered, which belongs to the genus Pseudomonas. Concomitantly, morphologically uniform bacteria were found encapsulated in bacteriocytes. These findings indicate that certain bacteria, possibly of the genus Pseudomonas, are able to persist for long periods in host bacteriocytes. Subsequent to performing a previously established infection assay with S. domuncula, a potentially pathogenic Vibrio sp. was isolated from the tissues. Furthermore, the host tissue disintegrated and asexual propagation bodies (gemmules) were formed. In order to gain insights into the molecular events occurring after bacterial infection, the stress-response kinases, p38 protein kinase and JNK protein kinase, were analyzed. It is demonstrated that these two kinases are activated (phosphorylated) upon incubation of the tissue with the bacterial endotoxin lipopolysaccharide (LPS). Moreover, LPS strongly inhibits protein synthesis. It is concluded that there are many functionally different interactions between S. domuncula and bacteria and that the animal possesses mechanisms to differentiate between bacteria and to respond accordingly.
    Materialart: Article , PeerReviewed
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
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