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  • Biochemistry and Biotechnology  (1)
  • CTM2008-04517; CTM2009-06269-E; CTM2010-11955-E/MAR; DATE/TIME; EMSODEV; EMSO implementation and operation: DEVelopment of instrument module; EMSO-Link; ES5110020; Fixed Point Open Ocean Observatories Network; FixO3; Implementation of the Strategy to Ensure the EMSO ERICs Long-term Sustainability; Instalació de sensors en observatorio submari expansible OBSEA; Instalacion de equipos en superfície para la ampliación de las prestaciones del observatorio submarino obsea; Instrumentación y tecnologías aplicadas al estudio, caracterización y explotación sostenible del medio marino; Integración de sensores para monitorización submarina en una red con sincronización temporal; Interoperabilidad e instrumentación de plataformas autónomas marinas para la monitorización sísmica; Interoperabilidad en redes de sensores marinos y ambientales; Interoperabilitat en xarxes de sensors marins i ambientals; INTIMAS; INTMARSIS; JERICO-NEXT; Joint European Research Infrastructure network for Coastal Observatory – Novel European eXpertise for coastal observaTories; MarInTech; MELOA; MeteoMet2; Metrology for essential climate variables; Multi-purpose/Multi-sensor Extra Light Oceanography Apparatua; NeXOS; Next generation, Cost-effective, Compact, Multifunctional Web Enabled Ocean Sensor Systems Empowering Marine, Maritime and Fisheries Management; Nuevas tecnologías para el seguimiento de la acidificación marina en el espacio natural Costa del Garraf; OBSEA:OBSEA:2009-05; Operatividad laboratorio submarino obsea; OPOBSEA; Pressure, atmospheric; PT2009-0080; Redes de sensores submarinos acústicos aplicados al seguimiento de especies de interes comercial; Redes de sensores submarinos autónomos y cableados aplicados a la monitorización remota de indicadores biológicos; RESBAC; RESBIO; SARTI-MAR; SINEOS; Sismòmetre marí digital amb connexió per cable; Sistemas inalambricos para la extension de observatorios submarinos; Sistemes dAdquisició Remota de dades i Tractament de la Informació en el Medi Marí; Temperature, air; VALTEC09-1-0059; Weather Station, 150WX, Airmar; Wind direction; Wind speed
  • General Chemistry
  • Organic Chemistry
  • Size-at-age
  • 1990-1994  (2)
  • 1994  (2)
Sammlung
Schlagwörter
  • Biochemistry and Biotechnology  (1)
  • CTM2008-04517; CTM2009-06269-E; CTM2010-11955-E/MAR; DATE/TIME; EMSODEV; EMSO implementation and operation: DEVelopment of instrument module; EMSO-Link; ES5110020; Fixed Point Open Ocean Observatories Network; FixO3; Implementation of the Strategy to Ensure the EMSO ERICs Long-term Sustainability; Instalació de sensors en observatorio submari expansible OBSEA; Instalacion de equipos en superfície para la ampliación de las prestaciones del observatorio submarino obsea; Instrumentación y tecnologías aplicadas al estudio, caracterización y explotación sostenible del medio marino; Integración de sensores para monitorización submarina en una red con sincronización temporal; Interoperabilidad e instrumentación de plataformas autónomas marinas para la monitorización sísmica; Interoperabilidad en redes de sensores marinos y ambientales; Interoperabilitat en xarxes de sensors marins i ambientals; INTIMAS; INTMARSIS; JERICO-NEXT; Joint European Research Infrastructure network for Coastal Observatory – Novel European eXpertise for coastal observaTories; MarInTech; MELOA; MeteoMet2; Metrology for essential climate variables; Multi-purpose/Multi-sensor Extra Light Oceanography Apparatua; NeXOS; Next generation, Cost-effective, Compact, Multifunctional Web Enabled Ocean Sensor Systems Empowering Marine, Maritime and Fisheries Management; Nuevas tecnologías para el seguimiento de la acidificación marina en el espacio natural Costa del Garraf; OBSEA:OBSEA:2009-05; Operatividad laboratorio submarino obsea; OPOBSEA; Pressure, atmospheric; PT2009-0080; Redes de sensores submarinos acústicos aplicados al seguimiento de especies de interes comercial; Redes de sensores submarinos autónomos y cableados aplicados a la monitorización remota de indicadores biológicos; RESBAC; RESBIO; SARTI-MAR; SINEOS; Sismòmetre marí digital amb connexió per cable; Sistemas inalambricos para la extension de observatorios submarinos; Sistemes dAdquisició Remota de dades i Tractament de la Informació en el Medi Marí; Temperature, air; VALTEC09-1-0059; Weather Station, 150WX, Airmar; Wind direction; Wind speed
  • General Chemistry
  • Organic Chemistry
  • Size-at-age
    • +
Verlag/Herausgeber
Erscheinungszeitraum
  • 1990-1994  (2)
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Theoretical Calculations of β-Lactam Antibiotics. Part VI. AM1 calculations of alkaline hydrolysis of clavulanic acid (1994)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 77 (1994), S. 1557-1569 
    Details
    ISSN: 0018-019X
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: The gas-phase basic hydrolysis of clavulanic acid (a) was studied by using the AM1 semi-empirical method. The results obtained show that the hydroxyethylidene side chain at C(2) is pivotal to the stability of the different reaction products involved. The products with an open oxazolidine ring are more stable than those with a closed ring fused to the β-lactam ring. This behaviour differs from that of penicillins and cephalosporins where the most stable degradation products are those with an intact thiazolidine or dihydrothiazine ring, respectively, fused to the β-lactam ring. The different chemical reactivity of clavulanic acid relative to penicillins and cephalosporins could explain the disparate behaviour of the latter two types of compound towards β-lactamases. Once the acyl-enzyme intermediate of clavulanic acid has been formed, it can evolve with cleavage of the oxazolidine ring to form a difficult to deacylate compound.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/hlca.19940770611
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Double- and single-strand conformation polymorphism analysis of point mutations and short tandem repeats (1994)
    Weinheim : Wiley-Blackwell
    Electrophoresis 15 (1994), S. 566-571 
    Details
    ISSN: 0173-0835
    Schlagwort(e): Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Single point mutations in small DNA fragments and single unit differences in simple repetitive DNA can be detected as double-strand conformation polymorphisms using polyacrylamide gel electrophoresis, with and without sodium dodecyl sulfate, even at temperatures as low as 3°C. Changes in a single base are distinguished by means of the analysis of the heteroduplexes, and changes in more than two bases can be distinguished in both homoduplexes and heteroduplexes. Polymerase chain reaction (PCR) conditions can be designed not only to amplify homoduplexes, heteroduplexes and singlestrand DNA at the same time, but also to focus the analysis on either singlestrand conformation polymorphism (SSCP) or double-strand conformation polymorphism (DSCP). DSCP seems to be advantageous in typing DNA polymorphisms or mutations in loci with few variants, but, because it is necessary to have a simple pattern of all possible combinations of the alleles, it is not as advantageous in typing systems with many variants.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/elps.1150150177
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
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