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  • Analytical Chemistry and Spectroscopy  (98)
  • Humans  (49)
  • Organic Chemistry  (44)
  • Biochemistry and Biotechnology  (38)
  • Wiley-Blackwell  (180)
  • American Association for the Advancement of Science (AAAS)  (49)
  • Cambridge University Press
  • Springer
  • Wiley
  • 1980-1984  (229)
  • 1970-1974
  • 1981  (229)
Collection
Keywords
Publisher
  • Wiley-Blackwell  (180)
  • American Association for the Advancement of Science (AAAS)  (49)
  • Cambridge University Press
  • Springer
  • Wiley
Years
  • 1980-1984  (229)
  • 1970-1974
Year
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 23 (1981), S. 863-877 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Results of pilot plant studies using a glass airlift fermentation device (55 liter fermentation volume) have proven the relative merits of such a system in the fermentation of a filamentous mold, Monascus purpureus, on 4% (w/w) starch media. The resultant overall yield of cell mass (Yx/s) of 0.38 was an appreciable increase over the 0.32 obtained with a pilot scale stirred tank fermentor previously studied. Power requirements of the airlift fermentor were approximately 50% of those for the mechanically agitated system. The lack of mechanical shear in the airlift system provides a more gentle environment or the cultivation of organisms than does the high degree of shear prevalent in the mechanically agitated vessels. Mass transfer of oxygen to the aqueous phase of the fermentation volume is improved significantly through use of the airlift device. Mass transfer coefficients in the range of 200 reciprocal hr were obtained to approximately 80 reciprocal hr in the stirred tank fermentor.
    Additional Material: 8 Ill.
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 16 (1981), S. 123-125 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Two NQR lines were observed for 35Cl in 2,5-dichloro-4-nitroaniline at room temperature, using a self-quenched super-regenerative spectrometer. Analysis of the Zeeman effect on the two lines using a cylindrical single crystal reveals that the crystal belongs to the monoclinic system. The principal field gradient Z axes enclose an angle of 35° and 28° in the cases of the low and high frequency resonance lines, respectively. The b axis is parallel to 81°, 280°. The unit cell contains either two or a multiple of two molecules. The molecules in the crystal can be arranged into two sets, with the molecular planes in each set being parallel among each other. The angle subtended between the two planes is 159° and each of the planes is inclined to the b axis at an angle of 79.5°. There is an in-plane bending of the two C—Cl bonds by 5.5°. The ionic, single bond and double bond characters of the C—Cl bonds for both chlorines are almost equal, and are in the ratio 24:73:3.
    Additional Material: 3 Ill.
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  • 3
    Publication Date: 1981-12-04
    Description: Leucine catabolism is regulated by either of the first two degradative steps: (reversible) transamination to the keto acid or subsequent decarboxylation. A method is described to measure rates of leucine transamination, reamination, and keto acid oxidation. The method is applied directly to humans by infusing the nonradioactive tracer, L-[15N,1-13C]leucine. Leucine transamination was found to be operating several times faster than the keto acid decarboxylation and to be of equal magnitude in adult human males under two different dietary conditions, postabsorptive and fed. These results indicate that decarboxylation, not transamination, is the rate-limiting step in normal human leucine metabolism.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matthews, D E -- Bier, D M -- Rennie, M J -- Edwards, R H -- Halliday, D -- Millward, D J -- Clugston, G A -- AM-25994/AM/NIADDK NIH HHS/ -- HD-10667/HD/NICHD NIH HHS/ -- RR-00954/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1129-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7302583" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Carbon Isotopes ; Humans ; Kinetics ; Leucine/*metabolism ; Male ; Models, Biological ; Nitrogen Isotopes ; Oxidation-Reduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The title compounds have been isolated and their structures determined by X-ray crystallography. Their relative stability is discussed in terms of theory and experiment. The endo-adduct is the thermodynamically more stable one.
    Additional Material: 2 Ill.
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  • 5
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Bromination of (-)-4-hydroxy-N-methylmorphinan-6-one (3), prepared from natural morphine, with 1 mol of bromine in acetic acid, afforded the 1-bromo ketone 5. The structure of 5 was assigned by 13C-NMR.spectroscopy, and confirmed by X-ray diffraction analysis of its hydrobromide salt. It is suggested that monobromination of synthetic (±)-2,4-dihydroxy-N-formylmorphinan-6-one (7) takes in principle a similar course, although the 13C-NMR.spectrum of the primary reaction product 9 could not be measured because of insolubility in commonly used solvents. Monobromination of (-)-4-acetoxy-N-formylmorphinan-6-one (12) of the natural series, and of (±)-2,4-diacetoxy-N-formylmorphinan-6-one (8) of the synthetic series, followed by treatment of the monobrominated ketones with potassium carbonate in methanol resulted in closure of the O-bridge, and afforded after acid hydrolysis, the corresponding 4,5-epoxy-morphinan-6-ones (-)-16 and (±)-17 respectively. This variation of the ring closure reaction represents a novel and convenient method to convert 4-hydroxymorphinan-6-ones into their corresponding 4,5-epoxymorphinan-6-ones, without involving aromatic bromination and with only 1 mol of bromine.
    Additional Material: 1 Ill.
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  • 6
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Silicon-Nitrogen Bonds. XXXIX. Kinetic Studies on the Spontaneous Hydrolysis, Alcoholysis, and Phenolysis of SilylaminesIt could be shown by polarimetric and DC-metric methods that hydrolysis, alcoholysis, and phenolysis of silylamines are of second order and lead to equilibria.The rate of equilibrium establishment is determined by the position of a preceding protonation equilibrium and by steric effects. The position of the equilibria depends on inductive and steric effects. The enthalpy of activation for the ethanolysis of Me3SiNHPh was determined to 27,2 kJ/mol and the entropy of activation to -231 J/K · mol. The mechanism of the reactions is given.
    Additional Material: 4 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 323 (1981), S. 793-800 
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Stereochemie von diastereomeren 3-Dialkylaminopropanolen und entsprechenden O-DerivatenErythro- und threo-3-Dialkylamino-1-phenyl(1-ethyl)-2-methyl-1-propanole 1a-c, 2a, b wurden durch fraktionierte Umkristallisation bzw. Säulenchromatographie über Kieselgel oder Aluminiumoxid isoliert. Weiterhin wurden die diastereomeren O-Derivate 3-8 erhalten. Eine erythro-threo-Isomerisation wurde mit Säuren durchgeführt. Die relativen Konfigurationen und bevorzugten Konformationen wurden durch 1H-NMR- und IR-Spektroskopie bestimmt.
    Additional Material: 3 Tab.
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 23 (1981), S. 2417-2420 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Relatively poor SCP production (4.2 mg/L h) was obtained using C. cellulolyticum and ground aspen wood treated with steam at atmospheric pressure for 1 h. The percentage of protein in the final product increased to 21.4% at a specific growth rate of 0.15 h-1 when the wood sample was treated with steam at a higher pressure (280 psig for 4 min) according to the "Stake" process. Alkali treatment (10% and 15% w/w at 121°C for 30 min), known to solubilize hemicelluloses and some of the lignin, gave intermediate results. More complete delignification of wood using NaClO2 increased the protein composition in the final product to 37.9%, at a specific growth rate of 0.19 h-1. Cellulose utilization was lowest (12.4%) in the case of the wood treated with steam at atmospheric pressure; it was higher at 75.3 and 78.5% for wood treated with NaOH at 10 and 15% w/w levels, respectively. The cellulose utilization was highest (90%) for wood treated with NaClO2.
    Additional Material: 1 Tab.
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 23 (1981), S. 2293-2306 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The gases CO, CO2, and H2 were used as substrates in anaerobic fermentations producing organic acids. Various mixed bacterial sources were used, including sewage sludge digester effluent, rabbit feces, and soil. Nonsterile microorganism selection was carried out using CO2/H2 and CO/H2 as the primary carbon and energy sources. Cultures were grown in specially designed, high-pressure (to 70 psig) flasks. Methanogenic bacteria were eliminated from the cultures. Liquid products of the fermentations were acetic through caproic acids, with the even-numbered acids predominating. Carbon balances showed conclusively that acetic acid was formed from carbon contained in the CO or CO2 feed gas. Measurements made included rates of acid product formation, cell density, and degree of gas utilization. Limited characterization of the microorganisms was also performed. Production of organic acids by mixed culture inocula from CO2/H2 or CO/H2 had not been reported previously. Application of this work is to the production of organic chemicals from synthesis gas (SNG), produced by the gasification of fossil fuels (peat, lignite, and various ranks of coals), biomass (agricultural and forest residues, and various biomass crops grown expressly for energy recovery), and municipal solid waste.
    Additional Material: 6 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 4 (1981), S. 366-384 
    ISSN: 0935-6304
    Keywords: GC/MS ; Capillary columns, fused silica ; Priority pollutants ; Quantitation ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Operational characteristics have been determined for fused silica capillary column (FSCC) GC/MS as applied to “extractable” priority polutants. Chromatographic data show excellent relative retention time (RRT) intralaboratory precision and interlaboratory accuracy when multiple internal standards are empolyed. Potential chromatographic problems, such as column overload and “double peaking”, are addressed. Response factor relative standard deviations (RSD) at 50 ng for most of the extractable priority pollutants over the long term indicated precise determination (i.e. RSD generally ≤ 10%). Linearity was demonstrated over two orders of magnitude for FSCC GC/MS analysis of compounds with relatively low and high RF (response factor) values. Potential quantitative problems, such as saturation, are discussed. For certain aromatic priority pollutants interlaboratory RF agreement was observed. This was noted as perhaps the most important property of FSCC GC/MS analysis when the multiple internal standard approach is utilized. Determinations of extractable priority pollutants are directly compared for paced column GC/MS and FSCC GC/MS analysis of separate and composited extracts. For six extracts analyzed in triplicate, the latter configuration was shown to produce more consistent results. In view of the superior analysis logistics of composite extract FSCC GC/MS analysis, this approach was established as the preferred method for the analysis of priority pollutants classified as extractable.
    Additional Material: 12 Ill.
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