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  • Animals  (15)
  • ASTRONOMY
  • LUNAR AND PLANETARY EXPLORATION
  • Solar Physics
  • American Association for the Advancement of Science (AAAS)  (15)
  • 1995-1999
  • 1980-1984  (15)
  • 1981  (15)
Collection
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (15)
Years
  • 1995-1999
  • 1980-1984  (15)
Year
  • 1
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    Auditory intensity discrimination after selective loss of cochlear outer hair cells (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-06-12
    Description: The contributions of the inner and outer hair cells of the mammalian cochlea to auditory intensity discrimination were evaluated in a combined behavioral-anatomical study of the guinea pig. Intensity difference thresholds were unchanged from baseline values after selective destruction of outer hair cells, suggesting that those cells are unnecessary for normal intensity discrimination.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prosen, C A -- Moody, D B -- Stebbins, W C -- Hawkins, J E Jr -- NS 05065/NS/NINDS NIH HHS/ -- NS 05785/NS/NINDS NIH HHS/ -- NS 15108/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Jun 12;212(4500):1286-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7233219" target="_blank"〉PubMed〈/a〉
    Keywords: Acoustic Stimulation ; Animals ; *Auditory Threshold/drug effects ; Guinea Pigs ; Hair Cells, Auditory/*physiology ; Hair Cells, Auditory, Inner/drug effects/physiology ; *Hearing/drug effects ; Kanamycin/pharmacology ; Male
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Immunization of Baboons with Schistosoma mansoni Cercariae attenuated by gamma irradiation (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-06-26
    Description: Studies on the efficacy of a vaccine against schistosomiasis in young baboons (Papio anubis) disclosed that immunization with Schistosoma mansoni cercariae attenuated by gamma irradiation induced significant protection against subsequent infection with normal, viable S. mansoni cercariae. Such immunization resulted in reduced worm burdens (70 percent) and egg excretion rates (82 percent). These results support immunization as a potential method for schistosomiasis control.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stek M, F r -- Minard, P -- Dean, D A -- Hall, J E -- New York, N.Y. -- Science. 1981 Jun 26;212(4502):1518-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7233238" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Female ; *Immunization ; Mice ; Mice, Inbred Strains ; Papio ; Schistosoma mansoni/immunology/*radiation effects ; Schistosomiasis/prevention & control
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    The hormonal control of sexual development (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-03-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilson, J D -- George, F W -- Griffin, J E -- AM03892/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1981 Mar 20;211(4488):1278-84.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7010602" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anti-Mullerian Hormone ; Estradiol/metabolism/*physiology ; Female ; *Glycoproteins ; Gonadotropins/physiology ; *Growth Inhibitors ; Humans ; Male ; Morphogenesis ; Mullerian Ducts ; Ovary/embryology ; Rabbits ; Receptors, Androgen/metabolism ; *Sex Differentiation ; Testicular Hormones/*physiology ; Testis/embryology/secretion ; Testosterone/metabolism/*physiology ; Time Factors ; Urogenital System/embryology ; Wolffian Ducts
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Gene for neuraminidase activity on mouse chromosome 17 near h-2: pleiotropic effects on multiple hydrolases (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-04-03
    Description: The low activity of liver neuraminidase that is characteristic of mouse strain SM/J is inherited as a single gene on chromosome 17, near the major histocompatibility complex. This gene, neuraminidase-1 (Neu-1), is represented by the low activity allele Neu-1s in SM/J and the high activity allele Neu-1b in C57BL/6J and most other strains. Previously described variations in the posttranslational processing of acid phosphatase, alpha-mannosidase, arylsulfatase-B, and alpha-glucosidase are attributed to pleiotropic effects of this gene.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Womack, J E -- Yan, D L -- Potier, M -- New York, N.Y. -- Science. 1981 Apr 3;212(4490):63-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7209520" target="_blank"〉PubMed〈/a〉
    Keywords: Alleles ; Animals ; Chromosome Mapping ; Female ; H-2 Antigens/genetics ; Hydrolases/*metabolism ; Liver/enzymology ; Major Histocompatibility Complex ; Male ; Mice ; Mice, Inbred Strains/*genetics/metabolism ; Neuraminidase/*genetics ; Protein Precursors/*metabolism ; Recombination, Genetic ; Sialic Acids/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Chitin: New facets of research (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-15
    Description: Research on chitin as a marine resource is pointing to novel applications for this cellulose-like biopolymer. Discovery of nondegrading solvent systems has permitted the spinning of filaments, for example, for use as surgical sutures. New methods for preparing the bioactive alkyl glycoside of N-acetyl-D-glucosamine (the monomer unit of chitin) and a microcrystalline chitin has encouraged their use as promoters for growth of bifidobacteria and as an aid in digestion of high-lactose cheese whey by domestic animals. Chitin-protein complexes of several crustacean species show great variability in ratios of chitin to covalently bound protein and in residual protein in the "purified" chitins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Austin, P R -- Brine, C J -- Castle, J E -- Zikakis, J P -- New York, N.Y. -- Science. 1981 May 15;212(4496):749-53.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7221561" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed ; Animals ; Cheese ; Chemical Phenomena ; Chemistry ; Chickens ; *Chitin ; Crystallography ; Lactose/metabolism ; Proteins/analysis ; Sutures ; *Technology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    The golgi apparatus: two organelles in tandem (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-09-11
    Description: The Golgi apparatus consists of distinct cis and trans compartments that may act sequentially to refine the protein export of the endoplasmic reticulum by removing escaped endoplasmic reticulum proteins. Refinement may be a multistage process akin to fractional distillation; the stack of cisternae comprising the cis Golgi may be the plates in this distillation tower. The trans Golgi, consisting of the last one or two cisternae, may be the receiver that collects from the cis Golgi only its most refined fraction for later distribution to specific locations throughout the cell.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rothman, J E -- AM 27044/AM/NIADDK NIH HHS/ -- GM 25662/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1981 Sep 11;213(4513):1212-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7268428" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cell Compartmentation ; Endoplasmic Reticulum/*metabolism ; Glycoproteins/biosynthesis ; Golgi Apparatus/*physiology/ultrastructure ; Hexosyltransferases/metabolism ; Intracellular Membranes/metabolism ; Membrane Proteins/*metabolism ; Microscopy, Electron ; Protein Precursors/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Cerebral cortex responds rapidly to thyroid hormones (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-10-30
    Description: In rats subjected to thyroidectomy there was a two- to fourfold increase in cerebral cortex iodothyronine 5'-deiodinase activity within 24 hours. This increase was prevented by thyroxine replacement. The increased cortical 5'-deiodinase in chronically hypothyroid rats was normalized within 4 hours by a single intravenous injection of triiodothyronine. These results indicate that the adult central nervous system can give a very rapid biochemical response to thyroid hormone.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Leonard, J L -- Kaplan, M M -- Visser, T J -- Silva, J E -- Larsen, P R -- AM00727/AM/NIADDK NIH HHS/ -- AM18616/AM/NIADDK NIH HHS/ -- AM25340/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1981 Oct 30;214(4520):571-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7291997" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cerebral Cortex/*enzymology ; Iodide Peroxidase/*metabolism ; Liver/metabolism ; Male ; Peroxidases/*metabolism ; Rats ; Rats, Inbred Strains ; Thyroidectomy ; Thyroxine/*metabolism ; Time Factors ; Triiodothyronine/*metabolism ; Triiodothyronine, Reverse/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Optimization theory fails to predict performance of pigeons in a two-response situation (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-11-13
    Description: Optimization theory states that organisms behave in a way that maximizes reinforcement or "value." In a two-response situation, pigeons' response proportions approximately equaled reinforcement proportions, even when this behavior pattern substantially decreased the rate of reinforcement. Optimization or reinforcement maximization was not supported as the basic mechanism underlying choice behavior.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mazur, J E -- New York, N.Y. -- Science. 1981 Nov 13;214(4522):823-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7292017" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Choice Behavior/*physiology ; Columbidae/*physiology ; Models, Biological ; Reinforcement (Psychology)
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Intraventricular calcitonin inhibits gastric acid secretion (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-11-06
    Description: Parenteral and intracerebroventricular administration of calcitonin in rats resulted in the suppression of gastric acid secretion. This suppression also occurred in rats with insulin-induced hypoglycemia and after the administration of thyrotropin-releasing hormone. Intracerebroventricularly administered calcitonin was 1000 times more effective than parenterally administered calcitonin in suppressing gastric acid secretion. Calcitonin also inhibited the development of stress-induced ulcers in rats.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Morley, J E -- Levine, A S -- Silvis, S E -- New York, N.Y. -- Science. 1981 Nov 6;214(4521):671-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7292006" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*drug effects ; Calcitonin/administration & dosage/*pharmacology ; Gastric Juice/*secretion ; Injections, Intraventricular ; Male ; Peptic Ulcer/etiology ; Rats ; Rats, Inbred Strains ; Stress, Physiological/complications
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Species restriction of a monoclonal antibody reacting with residues 130 to 137 in encephalitogenic myelin basic protein (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-10-02
    Description: A monoclonal antibody (immunoglobulin G1) has been produced that reacts against myelin basic protein present in or extracted from the brains of many mammals-with certain important exceptions. Because of known species differences in amino acid sequences of basic protein and of certain peptide fragments, the binding site for this particular antibody appeared likely to include residues 130 to 137. Confirmation of this hypothesis was obtained by amino acid composition of the major immunoreactive peptides produced by thermolysin digestion of human basic protein and isolated by high-performance liquid chromatography.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sires, L R -- Hruby, S -- Alvord, E C Jr -- Hellstrom, I -- Hellstrom, K E -- Kies, M W -- Martemspm, R -- Deibler, G E -- Beckman, E D -- Casnellie, J E -- CA-19148/CA/NCI NIH HHS/ -- CA-25558/CA/NCI NIH HHS/ -- CA-26584/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1981 Oct 2;214(4516):87-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6169147" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Antibodies, Monoclonal ; Cattle ; Chickens ; Epitopes ; Guinea Pigs ; Humans ; Macaca ; Myelin Basic Protein/*immunology ; Peptide Fragments/immunology ; Rabbits ; Rats ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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