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  • ASTROPHYSICS  (295)
  • Humans  (122)
  • Life and Medical Sciences  (119)
  • 1980-1984  (536)
  • 1970-1974
  • 1983  (293)
  • 1981  (243)
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  • 1980-1984  (536)
  • 1970-1974
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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Gamete Research 4 (1981), S. 203-217 
    ISSN: 0148-7280
    Keywords: α-chlorohydrin ; antifertility agent ; ram ; sperm metabolism ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The effects of the male antifertility agent, α-chlorohydrin, six of its derivatives, and glycidol were studied on the metabolism of washed ram spermatozoa in vitro with fructose as substrate. The α-chlorohydrin derivatives were the amino, the phosphorylated, and four glycol-bridge (ketal) compounds. All compounds except glycidol, in a concentration between 0.1 and 100 mM, reduced the aerobic glycolsis and/or oxidation of fructose. However, there was not a high correlation between the ability of these compounds to inhibit the metabolism of ram spermatozoa in vitro and their antifertility activity when administered to male rats. Other factors are clearly involved in their antifertility activity, eg, the concentration of the compounds in the epididymis and their conversion of either more or less spermicidal compounds in the body.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 1981-12-04
    Description: Leucine catabolism is regulated by either of the first two degradative steps: (reversible) transamination to the keto acid or subsequent decarboxylation. A method is described to measure rates of leucine transamination, reamination, and keto acid oxidation. The method is applied directly to humans by infusing the nonradioactive tracer, L-[15N,1-13C]leucine. Leucine transamination was found to be operating several times faster than the keto acid decarboxylation and to be of equal magnitude in adult human males under two different dietary conditions, postabsorptive and fed. These results indicate that decarboxylation, not transamination, is the rate-limiting step in normal human leucine metabolism.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matthews, D E -- Bier, D M -- Rennie, M J -- Edwards, R H -- Halliday, D -- Millward, D J -- Clugston, G A -- AM-25994/AM/NIADDK NIH HHS/ -- HD-10667/HD/NICHD NIH HHS/ -- RR-00954/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1129-31.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7302583" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Carbon Isotopes ; Humans ; Kinetics ; Leucine/*metabolism ; Male ; Models, Biological ; Nitrogen Isotopes ; Oxidation-Reduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 1983-11-04
    Description: Three new reagents that react against human T cells were synthesized by covalently linking the toxin ricin to monoclonal antibodies recognizing differentiation antigens on the surface of T lymphocytes. Each of these immunotoxins selectively inhibited T-cell proliferation when the cells were incubated in the presence of lactose. Multipotent human stem cells were inhibited only at much higher concentrations. Mixtures of all three immunotoxins were more effective than any one alone. These reagents have the potential for preventing graft-versus-host disease in man.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vallera, D A -- Ash, R C -- Zanjani, E D -- Kersey, J H -- LeBien, T W -- Beverley, P C -- Neville, D M Jr -- Youle, R J -- CA-25097/CA/NCI NIH HHS/ -- CA-31618/CA/NCI NIH HHS/ -- CA-31685/CA/NCI NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1983 Nov 4;222(4623):512-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6353579" target="_blank"〉PubMed〈/a〉
    Keywords: *Antibodies, Monoclonal ; Antigen-Antibody Complex ; Bone Marrow/immunology ; *Bone Marrow Transplantation ; Hematopoietic Stem Cells/immunology ; Humans ; *Immunosuppressive Agents ; Lymphocyte Activation ; Ricin/*immunology ; T-Lymphocytes/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 1983-10-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Risch, S C -- Kalin, N H -- Janowsky, D S -- Cohen, R M -- Pickar, D -- Murphy, D L -- New York, N.Y. -- Science. 1983 Oct 7;222(4619):77.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6312560" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenocorticotropic Hormone/*blood ; Cholinergic Fibers/*physiology ; Endorphins/*blood ; Humans ; Physostigmine/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2011-08-18
    Description: NGC 7027 was observed with a multichannel grating spectrometer from 5.2 to 7.5 microns at a spectral resolving power of 120-200. Two new dust emission features are resolved at 5.62 and 6.95 microns, and for the first time the Ni II fine-structure line at 6.64 microns is detected. It is shown that a single molecular dust constituent might account for six of the nine observed dust features between 2 and 14 microns. The strength of the Ni II line indicates either that Ni is not depleted in the neutral gas, or that the line is formed at high density.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 274; 666-670
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  • 6
    Publication Date: 2011-08-18
    Description: Measurements of forbidden line Ar II 6.99 micron and Pf alpha 7.45 micron made from the Kuiper Airborne Observatory are presented for Sgr A, the H II region at the center of the Galaxy. These line strengths, when combined with ground-based measurements, suggest a factor of enhancement of two in the Ar/H ratio in the galactic center region relative to that in the sun and in the solar neighborhood. The accuracy of the determination is presently limited by the uncertainty in the collision strength for Ar(+).
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal; vol. 248
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  • 7
    Publication Date: 2011-08-18
    Description: Infrared spectrophotometry of the R-type carbon star HD 19557 is presented. Two unusual spectroscopic features are seen: a 3.1 micron band is lacking and a 2.8 micron band is present. Identifications are proposed for three previously unreported stellar absorption bands with electronic sequences of C2, CN, and C2H. The latter is proposed to be responsible for the 2.8 micron feature. The atmospheric structure of the star is studied with synthetic spectra, and an effective temperature between 2600 K and 3000 K is suggested. No SiC emission is seen at 11.3 microns, indicating that grain formation is not a viable process around the star. The lack of dust in R stars may suggest a salient difference between R and N types.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 270; July 1
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  • 8
    Publication Date: 2011-08-18
    Description: The importance of coordinating different types of observations of a comet is illustrated in terms of spectral data on Comet Bowell. Photometric data in 1980 indicated that OH emissions were occurring when the comet was still more than 4 AU from the sun. Further measurements were arranged with the IUE satellite, the photoelectric scanner at Cerro Tololo and the IR telescope on Mauna Kea. Several sizes of diaphragms were used in order to estimate variations with respect to aperture. Calculations were made to quantify the wavelengths observed as a function of the grains' cross-sections. The OH emission was confirmed by the spectrographic and photometric data. It is suggested that sufficient dark materials are present on the cometary surface to have enhanced the absorption of solar radiation to levels sufficient for heating and dissociating surface ice particles.
    Keywords: ASTROPHYSICS
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  • 9
    Publication Date: 2019-06-28
    Description: Measurements of forbidden Ne II lines at 12.8 microns and forbidden S IV at 10.5 microns are presented along a line through and perpendicular to the ionization front in M17 SW. These observations give evidence for ionization stratification within the front, with the most highly ionized material lying toward the east, opposite to the peak molecular emission and far-IR flux. This result supports the picture of M17 SW as a region where a molecular cloud is heated externally. The ionization equilibrium within the ridge and the nebular energetics suggest that the M17 H II region is largely excited by one or more nearby early O stars. The properties of the recently discovered radio point source in M17 are discussed.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 275; 130-134
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  • 10
    Publication Date: 2019-06-28
    Description: The J = 6 - 5 rotational transition of carbon monoxide has been detected in emission from the KL 'plateau source' in the Orion molecular cloud. The corrected peak antenna temperature is 100 K, and the FWHM line width is 26 km/sec. These observations were carried out using the 3 m telescope of the NASA IRTF (Infrared Telescope Facility) on Mauna Kea, Hawaii, and constitute the first astronomical data obtained at submillimeter wavelengths with a heterodyne system using a laser local oscillator. The data support the idea that the high-velocity dispersion CO in Orion is optically thin and set a lower limit to its temperature of approximately 180 K.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal; vol. 243
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