ISSN:
0935-6304
Keywords:
GC, GC/MS
;
Capillary, HMDS-deactivated
;
On-column injection
;
Nucleoside linkage isomers
;
Separation, structural assignment feasibilities
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The analysis of low-volatile polar nucleosides by (GC)2/FID and (GC)2/CI-MS, employing HMDS-deactivated glass capillary columns and on-column injection, is described. The four linkage isomers of a specific nucleoside, formed in the synthetic procedure, are in each case sufficiently well separated in the chromatogram; GC/CI-MS allows for a differentiation of N-7 and N-9 linkage isomers.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240030402
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