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  • Articles  (118)
  • Chemical Engineering  (60)
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  • 1975-1979  (118)
  • 1955-1959
  • 1979  (118)
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  • 1975-1979  (118)
  • 1955-1959
Year
Journal
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  • 1
    Electronic Resource
    Electronic Resource
    Acute effects ofSolanum malacoxylon on bone formation rates in growing rats (1979)
    Springer
    Calcified tissue international 28 (1979), S. 239-243 
    Details
    ISSN: 1432-0827
    Keywords: Solanum malacoxylon ; Bone formation ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The plantSolanum malacoxylon is responsible for a syndrome of hypercalcemia, soft tissue mineralization, and progressive wasting in South American cattle known asenteque seco orespichamento. There is evidence that a glycoside of 1,25-dihydroxycholecalciferol is the active principle in the plant. The basis for the hyperostosis seen in the disease is unclear. To study the acute effects on bone formation rates, 8-week-old rats were given an aqueous extract equivalent to 250 or 1000 mg ofSolanum daily per os for 7 days. Bones were labeled by injection of fluochrome 2 days before the start of treatment and 2 days prior to sacrifice. Morphometric evaluation of undecalcified sections of caudal vertebrae revealed an increased amount of trabecular bone in bothSolanum treated groups with no difference due to dose level. This was associated with an increase in the bone apposition rate on trabecular surfaces. No differences were found in the amount of osteoid or osteoid seam width. Periosteal apposition rate and endochondral bone formation were also measured and no significant differences found. The findings indicate that acute stimulation of cell level bone formation on trabecular surfaces may play a role in the hyperostosis seen in the naturally occurring condition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02441242
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  • 2
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    A direct role of dopamine in the rat subthalamic nucleus and an adjacent intrapeduncular area (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: The subthalamic nucleus, a clinically important component of the extrapyramidal motor system, and a lateral area extending into the peduncle contain catecholamine terminals and dopamine receptors coupled to adenylate cyclase. In addition, dopamine agonists administered in vivo enhance glucose utilization in the region. Thus, neuronal function in this region is directly affected by dopamine and dopaminergic drugs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brown, L L -- Markman, M H -- Wolfson, L I -- Dvorkin, B -- Warner, C -- Katzman, R -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1416-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505015" target="_blank"〉PubMed〈/a〉
    Keywords: Adenylyl Cyclases/metabolism ; Animals ; Brain Mapping ; Catecholamines/pharmacology ; Dopamine/pharmacology ; Enzyme Activation/drug effects ; Extrapyramidal Tracts/*metabolism/ultrastructure ; Glucose/metabolism ; Male ; Mesencephalon/*metabolism ; Neurons/metabolism ; Rats ; Receptors, Dopamine/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
    Electronic Resource
    Electronic Resource
    Estimation of phase diagrams and solubilities for aqueous multi-ion systems (1979)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 25 (1979), S. 759-762 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Calculation of the phase diagram for saturated aqueous multi-ion solutions of strong electrolytes, based upon use of the thermodynamic solubility products, is illustrated for the four-ion system: Na+, K+, Mg++, SO4=. Solid phases are identified along with the ion concentrations of the associated saturated solutions.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690250503
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  • 4
    Electronic Resource
    Electronic Resource
    The effect of hot drawing on the properties of short fiber reinforced extruded sheets (1979)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 19 (1979), S. 1046-1053 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The hot drawing of extruded composite sheets can be used to control the orientation of both matrix and reinforcing fibers. A study was made of the effect of draw ratio on the properties of an extruded polystyrene sheet containing 0 to 1 percent of short glass fibers. An increase in draw ratio resulted in an increase in fiber orientation. A model of a rigid fiber rotating in an elongational flow field was used to describe the effect of draw ratio on the final orientation distribution. An increase in draw ratio also caused an increase in the amount of fiber breakage. A shear-lag analysis was used to estimate the extent of damage as a function of draw ratio. It was also found that the mechanical properties were dependent upon both the draw ratio and fiber concentration.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760191413
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  • 5
    Electronic Resource
    Electronic Resource
    A comparison of the thermal and mechanical degradation of glassy polystyrene by Fourier transform infrared spectroscopy (1979)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 19 (1979), S. 162-165 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The thermal and mechanical degradation of glassy polystyrene has been studied by Fourier Transform Infrared, FT-IR, spectroscopy. Using difference spectroscopy we have found that the products formed from these two modes of degradation were significantly different. This result is in contrast with other workers who found similar products for the thermal and mechanical degradation of polystyrene by mass spectroscopy. Our result suggests a reassessment of the thermal activation mechanism for mechanically-induced bond scission. We have also found that the distribution of oxidation products appears to depend upon the environment in which the polymer is mechanically degraded. Finally, we have demonstrated the utility of FT-IR spectroscopy for studying the mechanical degradation of polymers.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760190220
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  • 6
    Electronic Resource
    Electronic Resource
    Darstellung und Molekülstruktur eines Metallclusters mit Cubanstruktur, [η5-C5H5Mo(CO)3HgMo] 4 (1979)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 112 (1979), S. 2413-2418 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Synthesis and Molecular Structure of a Metal Cluster with Cubane Structure, [η5-C5H5Mo(CO)3HgMo]4(4)The compound [η5-C5H5Mo(CO)3HgMo]4 has been isolated as an additional product of the reaction between [η5-C5H5Mo(CO)3]2, 2-butenyl chloride, and sodium amalgam. The X-ray structure (R = 0·050) analysis of this novel species revealed that the compound has a slightly distorted cubane structure, for the first time the cubane unit being built up by two different metal atoms (Mo and Hg).
    Notes: Die Verbindung [η5-C5H5Mo(CO)3HgMo]4 (4) wurde als weiteres Produkt der Reaktion zwischen [η5-C5H5Mo(CO)3]2, 2-Butenylchlorid und Natriumamalgam isoliert. Die Röntgenstrukturanalyse dieser neuartigen Spezies zeigt eine leicht verzerrte Cubanstruktur, bei der das Cubangerüst erstmals aus zwei verschiedenen Metallatomen (Mo und Hg) aufgebaut ist. Der R-Wert beträgt 0·050.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19791120708
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  • 7
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    Somatostatin cell processes as pathways for paracrine secretion (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-28
    Description: Somatostatin is produced by gastrointestinal endocrine cells that have long, nonluminal, cytoplasmic processes. Such processes terminate on other cell types, including gastrin-producing and hydrochloric acid-producing cells, whose functions are profoundly affected by somatostatin. The findings suggest that somatostatin cells control the functions of other cells through local release of the peptide by way of cytoplasmic processes. Also, certain other types of gastrointestinal endocrine cells have similar cytoplasmic prolongations, which may have analogous local (paracrine) regulatory functions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Larsson, L I -- Goltermann, N -- de Magistris, L -- Rehfeld, J F -- Schwartz, T W -- New York, N.Y. -- Science. 1979 Sep 28;205(4413):1393-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/382360" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Gastric Juice/*secretion ; Gastrins/secretion ; Humans ; Immunoenzyme Techniques ; Pyloric Antrum/cytology/*metabolism ; Rats ; Somatostatin/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Metabolic mapping of functional activity in the hypothalamo-neurohypophysial system of the rat (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-17
    Description: Physiological stimulation of the hypothalamo-neurohypophysial system by salt loading of rats resulted in a dramatically increased glucose utilization in the posterior pituitary but not in the paraventricular or supraoptic nuclei. The good correlation between glucose utilization and neural activity in the posterior pituitary (that is, nerve terminals) contrasted with the lack of correlation in the paraventricular and supraoptic nuclei (that is, the sites of the cell bodies of the same neurons). This difference in the metabolic response to functional activity between the two regions of these neurons can be explained by the differences in surface-to-volume ratios of these regions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schwartz, W J -- Smith, C B -- Davidsen, L -- Savaki, H -- Sokoloff, L -- Mata, M -- Fink, D J -- Gainer, H -- New York, N.Y. -- Science. 1979 Aug 17;205(4407):723-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462184" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Axons/metabolism ; Deoxyglucose/metabolism ; *Energy Metabolism/drug effects ; Hypothalamo-Hypophyseal System/*metabolism ; Male ; Nerve Endings/metabolism ; Paraventricular Hypothalamic Nucleus/metabolism ; Phenoxybenzamine/pharmacology ; Pituitary Gland, Posterior/metabolism ; Rats ; Supraoptic Nucleus/metabolism ; Water Deprivation ; Water-Electrolyte Balance
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Electronic Resource
    Electronic Resource
    Dissociation of renal cyclic AMP and phosphate responses to parathyroid hormone in uremia (1979)
    Springer
    Calcified tissue international 29 (1979), S. 147-154 
    Details
    ISSN: 1432-0827
    Keywords: Vitamin D ; Chronic uremia ; Rats ; Renal responsivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Various investigators have shown that chronic uremia is associated with a normal or exaggerated phosphaturic response to parathyroid hormone (PTH). To explore the relationship between progressive uremia, renal tubular cyclic AMP (cAMP), and inorganic phosphate (Pi) response to PTH and acidosis, in vivo and in vitro experiments were designed in rats with experimental uremia of 4–6 weeks’ duration. Both uremic and pair-fed control rats were treated with 1,25-dihydroxycholecalciferol (1,25(OH)2D3) and/or chronic NH4Cl feeding. Urinary Pi and cAMP and plasma immunoreactive PTH (iPTH) were measured as well as PTH- and NaF-stimulated cAMP from isolated renal tubules. Excretion of cAMP decreased by 30% in uremic as compared to control rats despite a 3-fold rise in Pi excretion. Acidosis superimposed on uremia did not further decrease cAMP excretion, nor did it significantly alter the elevated Pi excretion. 1,25(OH)2D3 treatment of uremic rats further lowered cAMP excretion although Pi excretion rose, hypercalcemia occurred, and plasma iPTH fell. In nonuremic control rats, 1,25(OH)2D3 treatment led to hypercalcemia, a progressive decrease in cAMP, and increase in Pi excretion. Isolated renal tubules from uremic or acidotic uremic rats revealed a 50% reduction in both PTH- and NaF-stimulated cAMP generation compared to control rat renal tubules. This observation was unchanged by 1,25(OH)2D3 treatment. Renal tubules of 1,25(OH)2D3-treated control rats demonstrated a decreased cAMP production in response to both PTH and NaF which was inversely related to the calcium content of the renal tubules. Renal tubular calcium levels of uremic rats, initially 3-fold elevated, also increased during 1,25(OH)2D3 treatment. These results are consistent with the hypothesis that progressive uremia results in a dissociation between PTH, urinary cAMP, and Pi excretion which cannot be explained by either metabolic acidosis or 1,25(OH)2D3 deficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02408070
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  • 10
    Electronic Resource
    Electronic Resource
    The effects of plasma constituents on diffusivity of oxygen (1979)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 25 (1979), S. 188-190 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690250124
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