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  • Articles  (71)
  • Other Sources
  • Animals  (71)
  • 2010-2014
  • 1975-1979  (71)
  • 1979  (71)
  • Natural Sciences in General  (71)
  • Sociology
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  • Articles  (71)
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  • 2010-2014
  • 1975-1979  (71)
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Journal
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  • 1
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    Embryonic development of identified neurons: temporal pattern of morphological and biochemical differentiation (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: Individually identified neurons can be recognized in grasshopper embryos, and are accessible to examination by morphological, physiological, and biochemical techniques from their birth to their maturation. Only after the axon of an identified neuron reaches its postsynaptic target does the neurotransmitter accumulate, the soma rapidly enlarge, and the central arborizations greatly expand.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goodman, C S -- O'Shea, M -- McCaman, R -- Spitzer, N C -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1219-22.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/36661" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Differentiation ; Central Nervous System/*embryology ; Ganglia/cytology ; Grasshoppers/cytology/embryology ; Morphogenesis ; Neurons/*cytology ; Neurotransmitter Agents/metabolism ; Octopamine/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Muscle fiber regeneration after transplantation: prediction of structure and physiology from electromyograms (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: Digitized electromyographic activity of transplanted extensor digitorum longus (EDL) muscles in cats differs from that of control EDL and anterior tibialis muscles lying adjacent to transplanted EDL muscles. In autotransplanted muscles, the cross-sectional area of the fibers shows a negative correlation with mean spike frequency and a positive correlation with mean amplitude. The mean frequency-amplitude products correlate with isometric tetanic tensions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gorniak, G C -- Gans, C -- Faulkner, J A -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1085-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451552" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Animals ; Cats ; Electrodes ; Electromyography/methods ; Muscles/cytology/physiology/*transplantation ; *Regeneration ; Transplantation, Autologous
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Radioimmunoassay of the insulin receptor: a new probe of receptor structure and function (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: A sensitive and specific radioimmunoassay for the insulin receptor has been developed employing receptor autoantibodies from the serum of a patient with insulin-resistant diabetes. The assay detects insulin binding sites at concentrations as low as 0.1 nanomolar; distinguishes between receptors originating from human placental membranes, human lymphoblastoid cells, and mouse liver membranes; and measures the receptor independently of its binding function. Down-regulation, or loss of binding after exposure to insulin, is associated with loss of immunoreactive receptor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Harrison, L C -- Flier, J -- Itin, A -- Kahn, C R -- Roth, J -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):544-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/83675" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigen-Antibody Reactions ; Binding Sites ; Binding Sites, Antibody ; Epitopes ; Female ; Humans ; Liver/analysis ; Lymphocytes/analysis ; Mice ; Placenta/analysis ; Pregnancy ; Radioimmunoassay/methods ; Receptor, Insulin/analysis/*immunology ; Solubility
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    DNA synthesis and mitosis in adult amphibian cardiac muscle cells in vitro (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-21
    Description: High-resolution autoradiography and fine structural analysis of adult newt heart tissue in long-term culture revealed that tritiated thymidine was concentrated in the nuclei of dedifferentiated myocardial cells. Mitotic chromosomes were observed in some of these cells. This demonstrates that adult amphibian myocardial cells in vitro are capable of DNA synthesis and mitosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nag, A C -- Healy, C J -- Cheng, M -- New York, N.Y. -- Science. 1979 Sep 21;205(4412):1281-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472744" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Division ; Cells, Cultured ; DNA/*biosynthesis ; *Mitosis ; Muscle Proteins/metabolism ; Myocardial Contraction ; Myocardium/*metabolism ; Salamandridae ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: Wild-type Chinese hamster V79 cells (6-thioguanine-sensitive) reduce the recovery of 6-thioguanine-resistant cells when they are cultured together at high densities, through a form of intercellular communication (metabolic cooperation). Cooperation is inhibited by 12-O-tetradecanoyl phorbol-13-acetate, rescuing the 6-thioguanine-resistant cells. These results may be useful in the study of an aspect of the mechanism of tumor promotion and in assaying for promoters.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yotti, L P -- Chang, C C -- Trosko, J E -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1089-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493994" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Communication/*drug effects ; Cell Membrane/drug effects ; Cricetinae ; Dose-Response Relationship, Drug ; Drug Resistance ; Phorbol Esters/*pharmacology ; Phorbols/*pharmacology ; Structure-Activity Relationship ; Tetradecanoylphorbol Acetate/pharmacology ; Thioguanine/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Retrograde amnesia for old (reactivated) memory: some anomalous characteristics (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: Old memory, when reactivated by cue exposure, was disrupted by mild or deep hypothermia treatments. New memory was impaired only by deep cooling. Moreover, old but not new learning showed spontaneous recovery. Old reactivated memory may be qualitatively different from newly acquired memory.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mactutus, C F -- Riccio, D C -- Ferek, J M -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1319-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/572083" target="_blank"〉PubMed〈/a〉
    Keywords: Aging ; Amnesia/*physiopathology ; Amnesia, Retrograde/*physiopathology ; Animals ; Avoidance Learning/physiology ; Humans ; Hypothermia/*physiopathology ; Male ; Memory/*physiology ; Rats ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Histofluorescence techniques provide evidence for dopamine-containing neuronal elements in canine kidney (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-03
    Description: Changes induced by hydrochloric acid in the excitation spectrum of catecholamine fluorophores associated with the innervation of the canine renal vasculature show that there are neuronal elements at the glomerular vascular poles containing predominantly dopamine. In contrast, the catecholamine fluorescence in the periadventitial layer of the arcuate arteries is derived from norepinephrine. The dopamine-containing structures may represent the prejunctional counterpart to the pharmacologically identified dopamine receptors in the renal vasculature. As such, this system may be involved in the normal regulation of renal blood flow and renin release.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dinerstein, R J -- Vannice, J -- Henderson, R C -- Roth, L J -- Goldberg, L I -- Hoffmann, P C -- New York, N.Y. -- Science. 1979 Aug 3;205(4405):497-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451614" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Catecholamines/analysis ; Dogs ; Dopamine/*analysis ; Kidney Glomerulus/*analysis/blood supply/innervation ; Microscopy, Fluorescence ; Neurons/*analysis ; Norepinephrine/analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    The central origin of efferent pathways in the carotid sinus nerve of the cat (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: The application of horseradish peroxidase to the central cut end of the carotid sinus nerve of the cat produced retrograde labeling of neurons in the ipsilateral medulla in the region of the nucleus ambiguus at anterior-posterior coordinates -8 to -10.5. These data coupled with previous electrophysiological observations suggest that the nucleus ambiguus may be the origin of an efferent inhibitory pathway to the carotid body.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉deGroat, W C -- Nadelhaft, I -- Morgan, C -- Schauble, T -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):1017-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472721" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carotid Sinus/cytology/*innervation ; Cats ; Efferent Pathways/cytology ; Glossopharyngeal Nerve/cytology ; Horseradish Peroxidase ; Medulla Oblongata/cytology ; Neural Inhibition
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Embryonic rodent brain contains estrogen receptors (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: Estradiol-binding proteins with the properties of putative estrogen receptors are present in cytosol extracts of embryonic mouse hypothalamus and other brain regions. These embryonic estrogen receptors are adultlike in their high affinity and limited capacity for estradiol, sensitivity to diethylstilbestrol, ability to adhere to DNA, and behavior during DNA-cellulose affinity chromatography. As early as 4 days before birth, mouse hypothalamus has approximately 40 percent of the adult concentration of hypothalamic estrogen receptors with these properties. These observations raise the possibility that embryonic rodent brain has the biochemical potential to respond to sex hormones and that the critical period of brain sexual differentiation could be initiated prenatally.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vito, C C -- Fox, T O -- New York, N.Y. -- Science. 1979 May 4;204(4392):517-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432656" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Animals ; Binding Sites ; Brain/*embryology ; Chromatography, Affinity ; Cytosol/metabolism ; Hypothalamus/embryology ; Mice ; Receptors, Estrogen/*metabolism ; Sexual Maturation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    High concentrations of glutathione in glandular stomach: possible implications for carcinogenesis (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: In laboratory rodents, concentrations of reduced glutathione (GSH) are exceedingly high (up to 7 to 8 millimolar) in the glandular gastric tissue compared to concentrations in other portions of the gastrointestinal tract or to those of most other organs. Gastric GSH varies diurnally, with the highest levels occurring in the late afternoon or early evening. Starvation, treatment with diethyl maleate, or cold-restraint stress all caused marked decreases in stomach GSH, whereas treatment with cobaltous chloride caused an increase in the GSH concentrations. The physiological significance of the high gastric GSH is unknown, but because this endogenous compound may strongly modulate (decrease or increase) the macromolecular binding of certain chemicals capable of inducing stomach tumors, the possible role of glutathione in the pathogenesis of chemically induced gastric cancer should be considered.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Body, S C -- Sasame, H A -- Body, M R -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):1010-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/572989" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Circadian Rhythm ; Cobalt/pharmacology ; Food Deprivation ; Glutathione/*metabolism ; Liver/metabolism ; Rats ; Stomach/*metabolism ; Stomach Neoplasms/*etiology ; Stress, Physiological/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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