ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Glucocorticoid-mediated alteration in growth factor binding and action: Analysis of the binding change (1978)
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 9 (1978), S. 69-77 
    Details
    ISSN: 0091-7419
    Keywords: dexamethasone ; epidermal growth factor ; human diploid fibroblasts ; cell proliferation ; permissive effect ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The addition of the glucocorticoid analog dexamethasone (DX) to serum-free cultures of human fibroblasts caused a twofold enhancement of the mitogenic response to epidermal growth factor (EGF), although DX by itself was not mitogenic. A basis for this effect was suggested by studies showing that DX also increased the cellular binding of 125I-EGF. DX increased the ability of the cells to bind 125I-EGF only at low physiological concentrations of this polypeptide. Thus, data from 125I-EGF binding to cells incubated without DX produced a linear Scatchard plot, whereas the data from 125I-EGF binding to DX-treated cells led to an upwardly curvilinear Scatchard plot. Measurements of 125I-EGF association with the cell surface and cytoplasm indicated that this binding change involved an alteration of cell surface EGF receptors. The binding change appeared not to involve negatively cooperative interactions between EGF receptors, nor a change in the number of receptors. The binding alteration could be explained by a model in which DX converted 25-30% of the cell surface EGF receptors to a form having a fourfold increased affinity.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jss.400090108
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Inhibition by protease inhibitors of binding of adrenal and sex steroid hormones (1978)
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 9 (1978), S. 421-426 
    Details
    ISSN: 0091-7419
    Keywords: aldosterone ; dexamethasone ; dihydrotestosterone ; estrogen ; progesterone ; steroid hormone receptor ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Binding of steroid hormones is inhibited by protease inhibitors and substrates. The protease inhibitors phenylmethyl sulphonylfluoride, tosyl-lysine chloromethyl ketone, and tosylamide-phenylethyl-chloromethyl ketone and the protease substrates tosyl arginine methyl ester and tryptophan methyl ester eliminate specific binding of aldosterone, dexamethasone, dihydrotestosterone, estrogen, and progesterone to their respective receptors. These protease inhibitors and substrates also inhibit binding of progesterone to the 20,000 molecular weight mero-receptor formed from the progesterone receptor in chick oviduct. The binding of estradiol to rat alpha-fetoprotein is inhibited by the protease inhibitors and substrates but not by tryptophan or tryptophan amide, indicating the importance of an ester structure in the inhibition of steroid binding. Our results suggest that all steroid hormone receptors have a site with both common structural features and a role in the regulation of steroid hormone binding.
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jss.400090312
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    facet.materialart.
    Unknown
    Origin of the Cheney-Palouse Scabland tract (1978)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: The Cheney-Palouse tract of the channeled scabland is the largest continuous tract of scabland in eastern Washington. The tract is composed of a varied assortment of bedrock erosional forms, loess islands, and gravel bars. Prominent bedrock longitudinal grooves and inner channels formed by macroturbulent plucking erosion of the jointed rock. Loess island forms vary as a function of their position within the flow. The three major types (submerged, partially submerged, and subaerially exposed) created sedimentologic conditions and resulting bar forms distinct from one another. Other bar forms, notably expansion bars, account for most of the sedimentation in the tract.
    Keywords: GEOPHYSICS
    Type: Texas Univ. at Austin The Channeled Scabland; p 117-130
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 4
    facet.materialart.
    Unknown
    Large-scale erosional and depositional features of the Channeled Scabland (1978)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: The channeled scabland is a great anastomosing complex of highly overfit stand channels eroded into the basalt bedrock and overlying sediments of the Columbia Plateau. Both the erosional and depositional bed forms in these channels are described according to a simple hierarchical classification. The catastrophic flood flows produced macroforms (scale controlled by channel width) through the erosion of rock and sediment and by deposition (bars). Mesoforms (scale controlled by channel depth) are also erosional and depositional.
    Keywords: GEOPHYSICS
    Type: The Channeled Scabland; p 81-115
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 5
    facet.materialart.
    Unknown
    Quaternary geology of the Channeled Scabland and adjacent areas (1978)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: The quaternary history of the channeled scabland is characterized by discrete episodes of catastrophic flooding and prolonged periods of loess accumulation and soil formation. The loess sequence was correlated with Richmond's Rocky Mountain glacial chronology. At least five major catastrophic flood events occurred in the general vicinity of the channeled scabland. The earliest episode occurred prior to the extensive deposition of the Palouse formation. The last major episode of flooding occurred between about 18,000 and 13,000 years ago. It probably consisted of two outbursts from glacial Lake Missoula.
    Keywords: GEOPHYSICS
    Type: The Channeled Scabland; p 17-35
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 6
    facet.materialart.
    Unknown
    A high order accurate finite element algorithm for high Reynolds number flow prediction (1978)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: A Galerkin-weighted residuals formulation is employed to establish an implicit finite element solution algorithm for generally nonlinear initial-boundary value problems. Solution accuracy, and convergence rate with discretization refinement, are quantized in several error norms, by a systematic study of numerical solutions to several nonlinear parabolic and a hyperbolic partial differential equation characteristic of the equations governing fluid flows. Solutions are generated using selective linear, quadratic and cubic basis functions. Richardson extrapolation is employed to generate a higher-order accurate solution to facilitate isolation of truncation error in all norms. Extension of the mathematical theory underlying accuracy and convergence concepts for linear elliptic equations is predicted for equations characteristic of laminar and turbulent fluid flows at nonmodest Reynolds number. The nondiagonal initial-value matrix structure introduced by the finite element theory is determined intrinsic to improved solution accuracy and convergence. A factored Jacobian iteration algorithm is derived and evaluated to yield a consequential reduction in both computer storage and execution CPU requirements while retaining solution accuracy.
    Keywords: FLUID MECHANICS AND HEAT TRANSFER
    Type: NASA-CR-157309
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 7
    facet.materialart.
    Unknown
    Morphometry of streamlined forms in terrestrial and Martian channels (1978)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: Streamlined erosional forms in the Channeled Scabland are compared with streamline features recognized in the region of the Kasei Vallis on Mars shown in Viking imagery. The morphometric analysis considers three physical parameters, length, measured parallel to the suggested flow direction; width, taken as the maximum width of the streamlined form perpendicular to the flow direction; and area, measured with a grid placed over the surface. These parameters are used to calculate a dimensionless parameter k, defined as the square of the length multiplied by pi over four times the area. For the 137 Scabland forms studied k values range from 1.0 to 8.3 with an average of 3.2. The k values for 47 Martian streamlined forms range from 1.5 to 12.0 with an average of 3.8. The rough similarity of these results suggests that the terrestrial and Martian features were formed by similar processes. The forms appear to have developed an ideal shape, sufficiently elongated to reduce pressure drag in the fluid creating them, but not so long as to create excessive skin resistance.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Lunar and Planetary Science Conference; Mar 13, 1978 - Mar 17, 1978; Houston, TX
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 8
    facet.materialart.
    Unknown
    The Spokane flood controversy and the Martian outflow channels (1978)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: The controversy over Bretz's hypothesis concerning the cataclysmic Spokane flood is discussed. Attention is directed to similarities between the Channeled Scabland of Washington and some Martian land features considered to be catastrophic flood channels. Characteristics of the enormous plexus of proglacial stream channels eroded into the loess and basalt of the Columbia Plateau in eastern Washington are described. The controversiality of the suggestion that a catastrophic flood is responsible for the Martian features is considered with respect to the Spokane flood controversy.
    Keywords: GEOPHYSICS
    Type: Science; 202; Dec. 22
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 9
    facet.materialart.
    Unknown
    The magnetopause energetic electron layer. I - Observations along the distant magnetotail (1978)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Instrumentation aboard Imp 8 was used to study the magnetopause energetic electron layer along the distant magnetotail, and the observations are discussed. The inner edge of the layer corresponds to the magnetopause boundary, and energetic electrons within the layer persistently stream tailward along local magnetosheath field lines. Pitch angles of electrons along the dusk magnetopause are often restricted to values less than approximately 40 deg, while along the dawnside of the tail somewhat larger pitch angles are normally seen. The differential energy spectra of electrons in the layer, the intensity enhancements, and the average directional intensities are characterized.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research; 83; Sept. 1
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 10
    facet.materialart.
    Unknown
    Morphological mapping of Martian outflow channels (1978)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: Geomorphic mapping of selected portions of Martian outflow channels was performed in order to facilitate comparisons to terrestrial landforms. We interpret the maps to illustrate a correspondence between Martian channel features and terrestrial landforms developed by catastrophic flood erosion in the Channeled Scabland. The following features all occur in remarkably similar arrangements on the flood-channel floors of both planets: streamlined uplands, longitudinal grooves, scour marks, inner channel cataracts, etched zones, and possible pendant bars.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Lunar and Planetary Science Conference; Mar 13, 1978 - Mar 17, 1978; Houston, TX
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...