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  • English  (70)
  • 2020-2024  (70)
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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Immunology. ; Psychiatry. ; Neuroscience. ; Immunology. ; Psychiatry.
    Description / Table of Contents: Preface -- A Brief History of Immunological Research into Psychosis and Pathways for Immune Influence of the Brain.-Basic Concept of Microglia Biology and Neuroinflammation in Relation to Psychiatry -- Epidemiological Studies of Prenatal and Childhood Infection and Schizophrenia -- Schizophrenia, Cytokines and Other Systemic Inflammatory Mediators [to include oxidative stress and lymphocyte alterations] -- Association between Schizophrenia, Microbial Infection and Microbiota -- Autoantibodies and psychosis -- Effect of Infection on Cognition in Schizophrenia and Healthy People -- Role of Infection, Autoimmunity, Atopic Disorders and the Immune System in Schizophrenia: Evidence from Epidemiological and Genetic Studies -- Microglial Activation and Psychotic Disorders: Evidence from Pre-clinical and Clinical Studies -- Early-Life Adversity, Systemic Inflammation, and Co-Morbid Physical and Psychiatric Illnesses of Adult Life -- Inflammation, Antipsychotic Drugs and Evidence for Effectiveness of Anti-inflammatory Agents in Schizophrenia.
    Abstract: This book provides a comprehensive summary of the cutting edge scientific evidence regarding the role of immune system in the pathogenesis and treatment of schizophrenia and related psychotic disorders. It illustrates the role of inflammation and immunity in schizophrenia drawing on both basic science and clinical research. The chapters provide up-to-date summaries of immunological risk factors for schizophrenia and related psychotic disorders, and underlying mechanisms as informed by neuroimaging, genetic, clinical and animal experimental studies. In addition, the book will illuminate the scope for immunological treatment for schizophrenia. .
    Type of Medium: Online Resource
    Pages: X, 244 p. 10 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030391416
    Series Statement: Current Topics in Behavioral Neurosciences, 44
    DDC: 612.8
    Language: English
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  • 2
    Keywords: Anatomy. ; Medical education. ; Neuroanatomy. ; Materials Microscopy. ; Anatomy. ; Medical Education. ; Neuroanatomy. ; Microscopy.
    Description / Table of Contents: Chapter 1. Past and Current Learning and Teaching Resources and Platforms -- Chapter 2. Developing a Flipped Classroom for Clinical Anatomy: Approaches to Pre-class Recordings and a Novel Approach to In-Class Active Learning -- Chapter 3. An Overview of Traditional and Advanced Visualization Techniques Applied to Anatomical Instruction Involving Cadaveric Dissection -- Chapter 4. Technology-Enhanced Preclinical Medical Education (Anatomy, Histology and Occasionally, Biochemistry): A Practical Guide -- Chapter 5. Integration of Gross Anatomy, Histology, and Pathology in a Pre-matriculation Curriculum: A Triple-Discipline Approach -- Chapter 6. Methods for Assessing Students’ Learning of Histology: A Chronology over 50 Years! -- Chapter 7. Using Stereoscopic Virtual Presentation for Clinical Anatomy Instruction and Procedural Training in Medical Education -- Chapter 8. Creating Virtual Models and 3D Movies Using DemoMaker for Anatomical Education -- Chapter 9. Teaching Cellular Architecture: The Global Status of Histology Education.
    Abstract: Curricula in the health sciences have undergone significant change and reform in recent years. The time allocated to anatomical education in medical, osteopathic medical, and other health professional programs has largely decreased. As a result, educators are seeking effective teaching tools and useful technology in their classroom learning. This edited book explores advances in anatomical sciences education, such as teaching methods, integration of systems-based components, course design and implementation, assessments, effective learning strategies in and outside the learning environment, and novel approaches to active learning in and outside the laboratory and classroom. Many of these advances involve computer-based technologies. These technologies include virtual reality, augmented reality, mixed reality, digital dissection tables, digital anatomy apps, three-dimensional (3D) printed models, imaging and 3D reconstruction, virtual microscopy, online teaching platforms, table computers and video recording devices, software programs, and other innovations. Any of these devices and modalities can be used to develop large-class practical guides, small-group tutorials, peer teaching and assessment sessions, and various products and pathways for guided and self-directed learning. The reader will be able to explore useful information pertaining to a variety of topics incorporating these advances in anatomical sciences education. The book will begin with the exploration of a novel approach to teaching dissection-based anatomy in the context of organ systems and functional compartments, and it will continue with topics ranging from teaching methods and instructional strategies to developing content and guides for selecting effective visualization technologies, especially in lieu of the recent and residual effects of the COVID-19 pandemic. Overall, the book covers several anatomical disciplines, including microscopic anatomy/histology, developmental anatomy/embryology, gross anatomy, neuroanatomy, radiological imaging, and integrations of clinical correlations. .
    Type of Medium: Online Resource
    Pages: X, 212 p. 77 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031367274
    Series Statement: Advances in Experimental Medicine and Biology, 1431
    DDC: 611
    Language: English
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  • 3
    Keywords: Sustainability. ; Physical geography. ; Economic development. ; Energy policy. ; Energy and state. ; Environmental management. ; Sustainability. ; Earth System Sciences. ; Development Studies. ; Energy Policy, Economics and Management. ; Environmental Management.
    Description / Table of Contents: Part 1: Introduction -- Chapter 1: The science of anthropogenic climate change -- Chapter 2: The Holocene, the Anthropocene, and the Planetary Boundaries -- Chapter 3: Managing the Earth System – Why we Need a Poly-Scalar Approach -- Chapter 4: Environmental Accounting, Absolute Limits, and Systemic Change -- Chapter 5: Resolving the Disconnect between Earth System Science, Management Theory, and Environmental Accounting -- Part 2: Developing Planetary Quotes -- Chapter 6: Translating the Planetary Boundaries into Planetary Quotas -- Chapter 7: A Planetary Quota for Carbon Dioxide.-Chapter 8: A Quota for Agricultural GHG Emissions (Methane and Nitrous Oxide) -- Chapter 9: A Quota for Forestland -- Chapter 10: A Quota for Ozone Depleting Substances -- Chapter 11: A Quota for Aerosols -- Chapter 12: A Quota for Water -- Chapter 13: A Quota for Nitrogen -- Chapter 14: The Phosphorus Quota -- Chapter 15: The Biodiversity Quota -- Chapter 16: The Imperishable Waste Quota. Part 3: The planetary Accounting Framework -- Chapter 17: The Planetary Accounting Framework.
    Abstract: This book presents a novel way to enable people, regardless of their scale of influence, to take responsibility for global environmental problems including climate change. It introduces a new framework called Planetary Accounting, which allows the Planetary Boundaries, non-negotiable limits for the environment, to be translated into limits for human activity. It shows how such limits can be broken down into chunks that can be managed at different levels (from individual and community, to business and sector levels, to cities and regions), and at any level of government. The book begins by summarising the science of climate change and introducing the notion of the Anthropocene – the “human age”. It highlights the importance of returning to and remaining within the Planetary Boundaries but shows that we can’t realistically do so unless we have a new approach to environmental accounting. The book then outlines how Planetary Accounting furnishes this new approach by combining sustainability science, change theory, and environmental accounting to create a scalable framework for environmental management that encourages systemic and individual change. The details of the science of and our human contribution to ten critical human pressures are then presented, and the book concludes with a guide for those seeking to apply Planetary Accounting in practice. Planetary Accounting could form the scientific underpinning of behaviour change programs, guide the development of policy and regulations, and provide both the basis for environmental laws, and the foundation of future global environmental agreements. It has been 50 years since the first views from space showed a blue planet alone in our solar system. This book is an historic opportunity to provide humanity for the first time with sufficient information to begin implementing Planetary Accounting. .
    Type of Medium: Online Resource
    Pages: XIV, 278 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811514432
    DDC: 304.2
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Sustainability. ; Economics. ; Power resources. ; Energy policy. ; Energy and state. ; Sustainability. ; Political Economy of Energy. ; Energy Policy, Economics and Management.
    Description / Table of Contents: Society, Energy and the Natural World -- Energy and Our Lives -- Pandemic Overview -- Our conversation with Mother Nature -- The math of our energy-dependent existence -- How to keep the Planet Human-friendly -- How do we get to where we need to be? -- Your Home and Lifestyle -- Cars, Tools and Mobility -- Communities lead the Way -- Your Country; Sustainable, Resilient and Secure -- How to invest for minimum disruption and maximum benefit -- How to drive change -- How to enjoy a sustainable lifestyle.
    Abstract: The Covid-19 pandemic is a repeating biophysical shock yet one for which our current socio-economic structure was not prepared. Climate change, scarcity, depletion of natural resources, and the inevitable transition to renewable energy are one time events. Taken together, they present an existential threat to human society. This book is a guide to navigating these megatrends, which confront us now but whose consequences will unfold over decades. By presenting clear options on the path to a renewable energy future, this book gives readers a broad perspective as well as detailed, well-illustrated examples to weigh in making decisions which will secure stability and prosperity for their families, their communities and their nations.
    Type of Medium: Online Resource
    Pages: XXIII, 418 p. 154 illus., 137 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030917821
    DDC: 304.2
    Language: English
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  • 5
    Publication Date: 2024-04-06
    Description: The outbreak of the global COVID-19 pandemic has presented unprecedented challenges to both developed and less developed local economies. The aim of the book is to uncover the best practises in responding to a pandemic from global perspectives, as well as from a trans-disciplinary point of view. Scholars from various spheres in arts, culture, education, health, environment, business and the public sector present their perspectives on the impacts, responses and consequences for local economies and communities. As a fundamental part of LED, the arts, culture, education, health, environment, business and the public sector domains were some of the hardest hit by the pandemic. The pandemic has certainly exposed the weaknesses of current development policies and calls for new, innovative measures in developing resilient local regions. This book will form an essential part of the development series of CENLED as it offers insight into how a global pandemic (COVID-19) impacted LED in the global North and Global South and the different responses from different spheres.
    Keywords: Local economic development;sustainable development;pandemic;resilience;tourism;environment;culture;climate;health entrepreneurship ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCM Development economics and emerging economies
    Language: English
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  • 6
    Publication Date: 2024-04-06
    Description: This book endeavours to outline case studies that promote sustainable Local Economic Development (LED) initiatives. It is generally believed that local governments are the foot soldiers of LED. However, this seems to be a myth, as local governments in South Africa and elsewhere have not yet fulfilled this mandate and have been struggling for several years to implement LED initiatives. The distinctive merit of this book lies in the way it combines the South African context with the wider international development context in ways that there is a flow of information and ideas both ways. The book is an essential part of this sequence of ideas development and action at a critical time for strategic action directed at a sustainable future. It showcases case studies and responses to the impacts of globalisation as a bridge between urban/rural and institutional action and reveals avenues for local government leadership in communities, research, student engagement and wider interactions.
    Keywords: Case study ; local government ; sustainable development ; local economic development ; women entrepreneurs ; Local Economic Development initiatives ; local government leadership ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics
    Language: English
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  • 7
    Publication Date: 2023-06-21
    Description: Groundwater abstraction and drainage are considered to be the main drivers for the salinization of low‐lying coastal groundwater systems, while the role of past boundary conditions is less clear. In this study, 3‐D paleo‐hydrogeological variable‐density groundwater flow and salt transport modeling (“paleo‐modeling”) is applied to reconstruct the evolution of groundwater salinities during the Holocene, that is, the last 9,000 years, in Northwestern Germany. Novel aspects of this study include the consideration of highly resolved time‐variant boundary conditions in a 3‐D paleo‐modeling framework, for example, sea‐level rise, surface elevation and coastline changes, development of drainage networks and groundwater abstraction, as well as the quantification of isolated processes impacting salinization. Results show that salinization was a function of sea‐level rise from 9000 BP until 1300 CE. The creation of the dike line ∼1300 CE set the starting point for increasing anthropogenic control of the hydro(geo)logical system: changes in surface elevation and drainage of low‐lying marshes have become main drivers for salinization after 1600 CE when peat was artificially degenerated. Moreover, changes in the dike line caused by storm floods impacted the salinities. Model results for 2020 CE match well with present‐day salinity observations. Yet, salinization will continue in the future, as the hydro(geo)logical system has not reached an equilibrium. The presented paleo‐modeling framework can be viewed as a blueprint for similar low‐lying coastal groundwater systems, influenced by marine transgression and human development. Thereby, it enables the reconstruction of meaningful present‐day salinity distributions, serving as a vital basis for modeling future groundwater systems in a changing climate.
    Description: Key Points: Salinization of a low‐lying coastal groundwater system during the Holocene, that is, 9000 BP until present‐day, was investigated. Sea‐level rise and the evolution of paleogeography were major controls on groundwater salinization during most of the time. Surface elevation changes due to land cultivation, as well as the development of drainage networks, control salinization since ∼1600 CE.
    Description: Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659
    Description: Bundesministerium für Bildung und Forschung http://dx.doi.org/10.13039/501100002347
    Description: https://doi.org/10.5281/zenodo.7633381
    Keywords: ddc:551.49 ; saltwater intrusion ; variable‐density groundwater flow ; salt transport ; sea‐level rise ; parameter estimation ; iMOD‐WQ
    Language: English
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  • 8
    Publication Date: 2023-11-18
    Description: Purpose: The application of plastic mulching differs globally as well as climate, soils, crops, and agricultural practices, making it difficult to generalize the reported impacts on soil. Because literature is scarce about the influence of plastic mulching on soil under temperate, humid climate, the objective of this study was to understand how multiannual plastic mulching influences central soil parameters and processes under Central European cultivation conditions to evaluate its impact on soil quality in the long term. Materials and methods: Central soil parameters and processes like leaching, aggregation, soil organic matter (SOM), and microbial biomass were investigated in a strawberry cultivation in Southwestern Germany. The field experiment compared a plastic-covered ridge–furrow system with subsurface drip irrigation (PC) to the same system with straw coverage (SC) in three soil layers (0–10, 10–30, and 30–60 cm) at seven dates within a 3-year period. Soil analyses comprised soil temperature and moisture, pH, bulk density, water-stable aggregates, soil organic carbon, dissolved organic carbon, and microbial biomass carbon and nitrogen. Results: Rainfall infiltration impeded by PC reduces soil moisture but neither reduces leaching nor promotes (macro-)aggregate formation or stability; however, it maintains a loose and friable soil structure in surface soil (0–5 cm), compared to SC. PC promotes SOM accumulation and shifted SOM composition to a more hardly degradable SOM, especially below the topsoil (10–60 cm). Furthermore, PC revealed no indications of an increased microbial biomass or activity accompanied with an enhanced SOM decomposition due to the shifted microclimate. The seasonal, time- and depth-dependent effects, observed in some parameters, emphasize the importance to include them in future studies for a more holistic process understanding. Conclusion: Our study showed no indications that multiannual plastic mulching influences soil quality within the 3 years of this study. Further research is advisable to support our findings on a larger scale and longer time periods and across various soil and crop types.
    Description: Universität Koblenz-Landau (3155)
    Keywords: ddc:631.4 ; Drip-irrigated ridge-furrow mulching ; Humid region ; Soil structure ; Aggregate stability ; Soil organic matter ; Soil microbial biomass
    Language: English
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  • 9
    Publication Date: 2023-11-18
    Description: Arctic warming and permafrost thaw visibly expose changes in the landscape of the Lena River delta, the largest Arctic delta. Determining the past and modern river regime of thick deltaic deposits shaping the Lena River mouth in north‐eastern Siberia is critical for understanding the history of delta formation and carbon sequestration. Using a 65 m long sediment core from the delta apex a set of sedimentological techniques is applied to aid in reconstructing the Lena River history. The analysis includes: (i) grain‐size measurements and the determination of the bedload composition; (ii) X‐ray fluorescence, X‐ray diffractometry, and magnetic susceptibility measurements and heavy mineral analysis for tracking mineral change; (iii) pH, electrical conductivity, ionic concentrations, and the δ〈sub〉18〈/sub〉O and δD stable isotope composition from ground ice for reconstructing permafrost formation. In addition; (iv) total and dissolved organic carbon is assessed. Chronology is based on; (vi) radiocarbon dating of organic material (accelerator mass spectrometry and conventional) and is complemented by two infrared – optically stimulated luminescence dates. The record stretches back approximately to Marine Isotope Stage 7. It holds periods from traction, over saltation, to suspension load sedimentation. Minerogenic signals do not indicate provenance change over time. They rather reflect the change from high energy to a lower energy regime after Last Glacial Maximum time parallel to the fining‐up grain‐size trend. A prominent minimum in the ground ice stable isotope record at early Holocene highlights that a river arm migration and an associated refreeze of the underlying river talik has altered the isotopic composition at that time. Fluvial re‐routing might be explained by internal dynamics in the Lena River lowland or due to a tectonic movement, since the study area is placed in a zone of seismic activity. At the southern Laptev Sea margin, onshore continental compressional patterns are bordering offshore extensional normal faults.
    Description: Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research
    Description: https://doi.org/10.1594/PANGAEA.945355
    Keywords: ddc:551 ; Lena River ; north‐eastern Siberia ; palaeoenvironment ; permafrost ; Quaternary
    Language: English
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  • 10
    Publication Date: 2024-04-19
    Description: The stable water isotopic composition in firn and ice cores provides valuable information on past climatic conditions. Because of uneven accumulation and post‐depositional modifications on local spatial scales up to hundreds of meters, time series derived from adjacent cores differ significantly and do not directly reflect the temporal evolution of the precipitated snow isotopic signal. Hence, a characterization of how the isotopic profile in the snow develops is needed to reliably interpret the isotopic variability in firn and ice cores. By combining digital elevation models of the snow surface and repeated high‐resolution snow sampling for stable water isotope measurements of a transect at the East Greenland Ice‐core Project campsite on the Greenland Ice Sheet, we are able to visualize the buildup and post‐depositional changes of the upper snowpack across one summer season. To this end, 30 cm deep snow profiles were sampled on six dates at 20 adjacent locations along a 40 m transect. Near‐daily photogrammetry provided snow height information for the same transect. Our data shows that erosion and redeposition of the original snowfall lead to a complex stratification in the δ〈sup〉18〈/sup〉O signature. Post‐depositional processes through vapor‐snow exchange affect the near surface snow with d‐excess showing a decrease in surface and near‐surface layers. Our data suggests that the interplay of stratigraphic noise, accumulation intermittency, and local post‐depositional processes form the proxy signal in the upper snowpack.
    Description: Plain Language Summary: We study the process of the formation of the stable water isotope signal in surface snow on the Greenland Ice Sheet to better understand temperature information which is stored as a climate proxy in snow and ice. Our data consist of high‐resolution surface topography information illustrating the timing and location of snowfall, erosion, and redeposition along a transect of 40 m, as well as stable water isotope records of the upper 30 cm of the snowpack sampled biweekly on 20 positions at the same 40 m long transect. The data cover a 2‐month period during the summer of 2019. We find that the isotopic composition shows spatial variability of layers with low and high values, presumably winter and summer layers. We further observe that prevailing surface structures, such as dunes, influence the snow deposition and contribute to the found variable structure of the climatic information. Eventually, snow accumulation alone cannot explain all of the observed patterns in the isotopic data which is likely related to exchange processes between the snow and the atmosphere which modify the signal in the snow column after deposition.
    Description: Key Points: Combining digital elevation models and repeated snow sampling reveals the heterogeneous buildup of δ〈sup〉18〈/sup〉O signal in the snow column. Surface structures (stratigraphic noise) substantially contribute to internal heterogeneity in δ〈sup〉18〈/sup〉O signature in the upper snowpack. Proxy signals are formed in the surface layer by local processes, advected downwards with limited post‐depositional influences below 10 cm.
    Description: Horizon 2020 Framework Programme http://dx.doi.org/10.13039/100010661
    Description: A. P. Møller Foundation, University of Copenhagen
    Description: US National Science Foundation, Office of Polar Programs
    Description: Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research
    Description: National Institute of Polar Research and Arctic Challenge for Sustainability
    Description: University of Bergen
    Description: Trond Mohn Foundation
    Description: Swiss National Science Foundation
    Description: French Polar Institute Paul‐Emile Victor, Institute for Geosciences and Environmental Research
    Description: University of Manitoba
    Description: Chinese Academy of Sciences
    Description: Beijing Normal University
    Description: https://doi.org/10.1594/PANGAEA.954944
    Description: https://doi.org/10.1594/PANGAEA.954945
    Description: https://doi.org/10.1594/PANGAEA.951583
    Description: https://doi.org/10.1594/PANGAEA.925618
    Description: https://doi.org/10.1594/PANGAEA.928827
    Description: https://www.agisoft.com/downloads/installer/
    Keywords: ddc:551 ; proxy ; Greenland ; isotopes ; structure‐from‐motion ; snow accumulation ; ice core
    Language: English
    Type: doc-type:article
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