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  • 1
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    Associative behavioral modification in hermissenda: cellular correlates (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-07-18
    Description: Three days of training consisting of trials of light paired with rotation produces a long-term modification of photopositive behavior in Hermissenda crassicornis. The behavioral modification depends on the temporal association of light and rotation. For animals that received light paired with rotation, significant increases in the spontaneous activity of type B photoreceptors were correlated with changes in photopositive behavior after training. A persistent tonic depolarization of type B photoreceptors can explain the cellular changes correlated with the long-term behavioral modification produced by the temporal association of light and rotation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Crow, T J -- Alkon, D L -- New York, N.Y. -- Science. 1980 Jul 18;209(4454):412-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17747814" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Retention of an associative behavioral change in Hermissenda (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-29
    Description: The nudibranch mollusk Hermissenda crassicornis is normally attracted to a test light. Three days of training consisting of 50 trials per day of light paired with a rotational stimulus led to a significant increase, lasting for days, in the animal's response latency to enter a test light. The group that received light associated with rotation was significantly different from groups subjected to nonassociative control procedures. Modifications of well-known sensory networks may be related to a behavioral change that shares several operational features with associative learning.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Crow, T J -- Alkon, D L -- New York, N.Y. -- Science. 1978 Sep 29;201(4362):1239-41.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694512" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Association Learning/*physiology ; Behavior, Animal/physiology ; Learning/*physiology ; Light ; Memory/*physiology ; Mollusca/*physiology ; Retention (Psychology)/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Neuropeptide Y distribution in the rat brain (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-08-26
    Description: A massive neuronal system was detected by immunocytochemistry and radioimmunoassay with antibodies to neuropeptide Y, the recently isolated peptide of the pancreatic polypeptide family. Immunoreactive cell bodies and fibers were most prevalent in cortical, limbic, and hypothalamic regions. Neuropeptide Y was extracted in concentrations higher than those of any other peptide hitherto discovered in the mammalian brain. Column chromatography of brain extracts and double immunostaining experiments indicate that neuropeptide Y is the endogenous brain peptide responsible for immunostaining of pancreatic polypeptide-like immunoreactivity in the mammalian brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Allen, Y S -- Adrian, T E -- Allen, J M -- Tatemoto, K -- Crow, T J -- Bloom, S R -- Polak, J M -- New York, N.Y. -- Science. 1983 Aug 26;221(4613):877-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6136091" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*metabolism ; Nerve Tissue Proteins/immunology/*metabolism ; Neuropeptide Y ; Neurotransmitter Agents/metabolism ; Rats ; Tissue Distribution
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
    Electronic Resource
    Electronic Resource
    Experimental Induction of β-Amyloid Plaques and Cerebral Angiopathy in Primates (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 695 (1993), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Notes: Moderate numbers of amyloid plaques with associated argyrophilic dystrophic neurites and cerebral amyloid angiopathy (CAA) but no neurofibrillary tangles (NFTs) were found in the brains of 3 middle-aged common marmosets (Callithrix jacchus) inoculated intracerebrally (i.e.) 6–7 years earlier with brain tissue from a patient with early onset Alzheimer's disease. The plaques and vascular amyloid stained positively with antibodies to β(A4)-protein. The brains of 3 age-matched control marmosets from the same colony did not show these neuropathological features, β-amyloid plaques and CAA (but no spongiform encephalopathy) were also found in the brain of a marmoset inoculated with brain tissue from a patient with priori disease with concomitant β-amyloid plaques and CAA. An occasional β-amyloid plaque was found in the brains of two marmosets inoculated with brain tissue from elderly patients. No β-amyloid plaques nor CAA were found in 6 other marmosets who were older than the inoculated marmosets, 10 further marmosets who were slightly younger but who had been inoculated several years previously with brain tissue which did not contain β-amyloid, and 10 younger marmosets who had been subjected to various neurosurgical procedures. These results suggest that β-amyloidosis is a transmissible process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1993.tb23057.x
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  • 5
    Electronic Resource
    Electronic Resource
    Neuropeptide Y distribution in human brain (1983)
    [s.l.] : Nature Publishing Group
    Nature 306 (1983), S. 584-586 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Human brains were obtained at postmortem from patients without history of neurological or psychiatric disease. The brains were immediately microdissected and then stored at -70 °C until extracted in boiling 0.5 M acetic acid (10ml per g wet weight tissue) for 15min. Material for ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/306584a0
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  • 6
    Electronic Resource
    Electronic Resource
    Psychopharmacology handbook (1979)
    [s.l.] : Nature Publishing Group
    Nature 277 (1979), S. 674-675 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] WITH these three volumes the Iversen-Snyder Handbook moves from the field of basic neuropharmacology into behavioural pharmacology. A total of 30 chapters contributed by 47 authors encompasses a range of subjects from the analysis of operant schedules (Dews and de Weese) to the localisation of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/277674a0
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  • 7
    Electronic Resource
    Electronic Resource
    Mode of Enhancement of Self Stimulation in Rats by Methamphetamine (1969)
    [s.l.] : Nature Publishing Group
    Nature 224 (1969), S. 709-710 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Stein4 attempted to test these hypotheses of the central actions of the amphetamines using self stimulation in the rat. Small doses of amphetamines markedly enhanced low response rates. Because a-methyl tryptamine, a long acting "tryptamine receptor" stimulant, did not mimic this action, Stein ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/224709a0
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  • 8
    Electronic Resource
    Electronic Resource
    Stereospecificity and clinical potency of neuroleptics (1977)
    [s.l.] : Nature Publishing Group
    Nature 267 (1977), S. 183-184 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ENNA et al.1 have drawn attention to the potential, and some of the difficulties, of studies of the stereo-specificity of neuroleptic drugs in elucidating the anti-schizophrenic action of these compounds. Although they have provided new data of considerable value we feel that they have obscured one ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/267183c0
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  • 9
    Electronic Resource
    Electronic Resource
    Impaired acquisition of a passive avoidance response after lesions induced in the locus coeruleus by 6-OH-dopamine (1976)
    [s.l.] : Nature Publishing Group
    Nature 259 (1976), S. 42-44 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The prediction that bilateral lesions of the locus coeruleus would impair learning capacity1,2,13 has been tested in a runway8 and a two-choice discrimination learning test14. Since moderately extensive lesions of the locus coeruleus did not impair acquisition in this latter task it has been ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/259042b0
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  • 10
    Electronic Resource
    Electronic Resource
    Cortical Synapses and Reinforcement: a Hypothesis (1968)
    [s.l.] : Nature Publishing Group
    Nature 219 (1968), S. 736-737 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A theory of cortical function which seems to overcome this difficulty has been proposed by Beurle6,7. In this theory, waves of neuronal activity are conducted across the cortical mass from sensory input to motor output. Use of particular pathways is assumed to lead to synaptic potentiation, but a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/219736a0
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