Publikationsdatum:
1980-04-25
Beschreibung:
A high incidence of tumor regression was observed in guinea pigs bearing transplantable, line-10 hepatocellular carcinomas when synthetic muramyl dipeptides combined with trehalose dimycolate in oil-in-water emulsions were injected directly into the tumors. These compounds are promising candidates to replace viable bacillus Calmette-Guerin in cancer immunotherapy in humans and animals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McLaughlin, C A -- Schwartzman, S M -- Horner, B L -- Jones, G H -- Moffatt, J G -- Nestor, J J Jr -- Tegg, D -- New York, N.Y. -- Science. 1980 Apr 25;208(4442):415-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7189295" target="_blank"〉PubMed〈/a〉
Schlagwort(e):
Acetylmuramyl-Alanyl-Isoglutamine/administration & dosage/*therapeutic use
;
Animals
;
Cord Factors/administration & dosage/*therapeutic use
;
Drug Combinations
;
Emulsions
;
Glycolipids/*therapeutic use
;
Glycopeptides/*therapeutic use
;
Immunotherapy
;
Liver Neoplasms, Experimental/*therapy
;
Lymphatic Metastasis
;
Structure-Activity Relationship
Print ISSN:
0036-8075
Digitale ISSN:
1095-9203
Thema:
Biologie
,
Chemie und Pharmazie
,
Informatik
,
Medizin
,
Allgemeine Naturwissenschaft
,
Physik
