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Salmonella typhimurium metC operator-constitutive mutations (1989)

Park, Young M. ; Stauffer, George V.

Oxford, UK : Blackwell Publishing Ltd

FEMS microbiology letters 60 (1989), S. 0

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ISSN: 1574-6968

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology

Notes: Abstract We used an Escherichia coli lac deletion strain lysogenized with a metC-lacZ fusion phage (λClac) to select operator-constitutive mutations in the Salmonella typhimurium metC gene control region. The mutations were located in a region containing 2 tandemly repeated 8 bp palindromes previously proposed to be the MetJ repressor binding site. Lysogens carrying λClac mutant phage exhibit high β-galactosidase levels that are only partially repressible by methionine. The results suggest that the mutations disrupt the methionine control system mediated by the metJ gene product.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1574-6968.1989.tb03433.x

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