ISSN:
1420-9071
Schlagwort(e):
α-MSH
;
analgesia
;
naloxone
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary α-MSH (0.1, 1, 10 μg) was administered intracerebroventricularly and its action on pain sensitivity was investigated by the hot-plate method in mice. α-MSH produced dose-dependent analgesia and this analgesic effect was prevented by naloxone (1 mg/kg, s.c.). It is possible that α-MSH may play a role in the mechanism of pain through endogeneous opioid systems.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02007691