ISSN:
0009-2940
Schlagwort(e):
Chemistry
;
Inorganic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Beschreibung / Inhaltsverzeichnis:
Reactions of Amino Acids with Trifluoroacetic Anhydride, III. 41-Substituted 2-Trifluoromethyl-4-(3,3,3-trifluor-2-trifluoroacetoxypropylidene)-2-oxazolin-5-onesEnol trifluoroacetates of type 1 (6) are rearranged into the title compounds 2a (8) by heating in acetonitrile. Stereochemistry and mechanism of the reaction are discussed. Addition of methanol to 4-alkylidene-2-trifluoromethyl-2-oxazolin-5-ones in trifluoroacetic acid yields 2-methoxy-3-oxazolin-5-ones.
Notizen:
Enol-trifluoracetate vom Typ 1 (6) lagern sich beim Erhitzen in Acetonitril in die Titelverbindungen 2a (8) um. Stereochemie und Mechanismus der Reaktion werden diskutiert. Die Addition von Methanol an 4-Alkyliden-2-trifluormethyl-2-oxazolin-5-one in Trifluoressigsäure liefert 2-Methoxy-3-oxazolin-5-one.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/cber.19751080724
