ISSN:
0935-6304
Schlagwort(e):
Gas chromatography
;
Capillary, nickel
;
„Transevaporator“ into packed pre-column as sampling technique prior capillary described
;
Application to volatile metabolite body fluid analysis for early detection of disease
;
Serum and human breast milk as examples
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Nickel capillary columns coated with moderately polarstationary phases such as Witconol can be used for the separation of the organic volatile fraction from biological fluids. A “transevaporator” sampling technique for the collection of the organic volatiles on glass beads from as little as 5 to 500 μl of biological fluids (e.g. urine, serum, amniotic fluid, breast milk, saliva, etc.) is described. The organic volatiles are thermally desorbed from the glass beads into a short precolumn cooled in liquid nitrogen, which overcomes the problems associated with sample introduction onto narrow-bore capillary columns. The application of the full analytical technique to problems associated with the early detection of disease is illustrated.
Zusätzliches Material:
5 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jhrc.1240020710
