ISSN:
0749-1581
Keywords:
EPR spin trapping
;
6,6,-dimethyl-3,4,5,6-tetrahydropyridine N-oxide
;
6-alkoxyl-2,2-dimethylpiperidine-1-oxyl
;
aminoxyl (nitroxide)
;
conformation
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The addition reactions of CH3(CH2)3O·, (CH3)2CHCH2O·, (CH3)2CHCH2CH2O·, (CH3)3CO· and (CH3)2C(CN)O· radicals to a novel six-membered cyclic nitrone, 6,6-dimethyl-3,4,5,6-tetrahydropyridine N-oxide (M2PyO), generate the corresponding 6-alkoxyl-2,2-dimethylpiperidine-1-oxyl aminoxyl (nitroxide) spin adducts. In benzene solution at room temperature, the preferential conformation of these spin adducts appears to be the anomeric conformer with the alkoxyl group in the axial position according to EPR spectroscopic conformational analysis of these aminoxyls. The anomeric effect in these aminoxyls might be the combination of electrostatic and molecular orbital interactions.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260331323
