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  • Articles  (50,858)
  • Chemistry  (50,842)
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  • 1990-1994  (50,858)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 216 (1994), S. 153-154 
    ISSN: 1572-946X
    Keywords: Chemistry ; Molecular Hydrogen ; Cloud Models
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Observations of the CO J=1-0 line are commonly used as a tracer for molecular material in clouds. The ratio of the H2 column density to the integrated intensity of this line,X, is often taken to be constant, despite theoretical and observational uncertainty. We have tried to identify how this ratio depends on cloud parameters, testing a simple theoretical argument suggesting its invariance with respect to density. The apparent constancy can be understood if clouds are clumpy on scales of Av ≈ 1-2 mag.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal for general philosophy of science 21 (1990), S. 275-292 
    ISSN: 1572-8587
    Keywords: Science ; cognitive sensory apparatus ; cultural evolution ; wealth-creating institutions ; intertheoretical competition ; free ; privatemarket order ; human capital
    Source: Springer Online Journal Archives 1860-2000
    Topics: Philosophy , Nature of Science, Research, Systems of Higher Education, Museum Science
    Notes: Summary To understand the present situation we must know something about its history. The ‘Rise of the West’, which grew out of the ‘European Miracle’, is a special case of cultural evolution. The development of science is an important element in this process. Cultural evolution went hand in hand with biological evolution. Evolutionary epistemology illuminates the achievements and the evolution of cognitive sensory apparatus of various species. Man's cognitive sensory apparatus is adapted to the ‘mesocosmos’, the world of medium-sized dimensions. The biological structures constitute the hardware of the cognitive sensory apparatus, while certain expectations and theories, which are ontogenetically apriori, constitute the corresponding system software. A distinction is introduced between ‘primary theories’ (linked to the sensory apparatus) and ‘secondary theories’. The latter are the result of attempts to meet the demand for an explanation of phenomena that cannot be explained in terms of ‘primary theories’. Two subsets of ‘secondary theories’ are compared: spiritualistic-personalized theories and scientific theories. From the historical point of view the scientific secondary theories are but a special subset of the class of secondary theories. From the systematic point of view it is instructive to focus on a comparison of the two subsets: what do they have in common? in what respects do they differ? The rise of scientific thinking is closely linked to the ‘European Miracle’. How (and when and why) did the West grow rich? To answer this question we must first produce an explanation of the principle: theories about the consequences of institutional arrangements. Then we can give a historical explanation of why this development took place in Europe and only there. It is claimed that the secret of success, economic wealth and the first approximations to relatively free societies, was the taming of the state, the taming of cleptocracy (independent of the nature of the agency having cleptocratic appetites, be it princes or parliaments). The taming of the state is a pre-democratic achievement. Finally, the consequences of institutional arrangements for scientific progress and innovation are examined. Only if the system is market-like, will it link individual effort with reward and, through the competitive process, encourage the wide dissemination and use of new ideas. There is no tradeoff between freedom on the one hand and economic success and the growth of scientific knowledge on the other. Freedom and the ensuing flexibility is the key to the past and to the future.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal for general philosophy of science 23 (1992), S. 129-151 
    ISSN: 1572-8587
    Keywords: Science ; politics ; acceptance of theories ; dangerous knowledge ; self-censorship ; objectivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Philosophy , Nature of Science, Research, Systems of Higher Education, Museum Science
    Notes: Summary In contrast to the opinion of numerous authors (e.g. R. Rudner, P. Kitcher, L. R. Graham, M. Dummett, N. Chomsky, R. Lewontin, etc.) it is argued here that the formation of opinion in science should be greatly insulated from political considerations. Special attention is devoted to the view that methodological standards for evaluation of scientific theories ought to vary according to the envisaged political uses of these theories.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Empirica 21 (1994), S. 259-270 
    ISSN: 1573-6911
    Keywords: Science ; technology ; knowledge ; production ; policy ; transfer sciences ; L52 ; O32
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Abstract This paper is concerned to develop the notion of transfer science to take account of what is perceived to be the emergence of a new mode of knowledge production. The new mode which is characterised by the production of knowledge in the context of application, by transdisciplinarity, by homogeneity and organisational diversity, by enhanced social accountability and reflexivity, and by new forms of quality control. The thrust of the new mode of knowledge production is to call into question conventional notions of knowledge transfer and focuses instead on the organisational and managerial implications of the emergence of a socially distributed knowledge production system. The paper concludes with a brief discussion of the policy implications of the emergence of the new mode of production. Needed in the new mode are science and technology policies which promote institutional permeability and policies which enable governments, acting through their civil service to act as “brokers” in the new knowledge production process. Such brokerage is necessary to enhance permeability between institutions within a particular country but also to increase co-operation and collaboration between institutions across countries.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of science education and technology 2 (1993), S. 521-540 
    ISSN: 1573-1839
    Keywords: Science ; education ; nationalism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Natural Sciences in General , Technology
    Notes: Abstract The history of curriculum debate involving science in the United States has touched all levels and concepts of schooling. It has involved a wide spectrum of competing interests and ideas. It has helped guide the framing of concepts as complex and influential as those of progress, human nature, and the national welfare. It has been a stage on which many players have entered, spoken, left, and returned (not always in the guise of farce). Above all, it is itself something from which a great deal can be learned: for in large part any current situation stands at the apex of this long history and cannot in any sense be divorced from what it reveals about the larger place of science and learning in American consciousness. Eric Hobsbawm once wrote that “the progress of schools and universities measures that of nationalism,” and that education generally is the “most conscious champion” of the state. History reveals this to be an enormous oversimplification, woefully expedient, and particularly so in the case of science. Here, in fact, nationalism itself can be revealed as a collision of many conflicting interests, myths, visions, and hopes, all of which at some point took the scientific as legitimating dais. No committed history could be so reductive. It must rather open both inward and outward, toward the past and its continued momentum.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of science education and technology 3 (1994), S. 7-15 
    ISSN: 1573-1839
    Keywords: Science ; technology ; models ; standards
    Source: Springer Online Journal Archives 1860-2000
    Topics: Natural Sciences in General , Technology
    Notes: Abstract We contrast the current science education reform effort with the reforms of the 1960s and suggest how the current effort could be enhanced. We identify insights from recent research that we believe can inform the reform process, in particular, to reach all science students and also impart a cohesive view of science. We propose an “alternative models” view of scientific explanation and show how this view would contribute to reforms of (1) course goals, (2) social aspects of science learning, (3) instructional practices, and (4) roles for technology.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of science education and technology 3 (1994), S. 77-88 
    ISSN: 1573-1839
    Keywords: Science ; science education ; National Science Foundation ; science and engineering education
    Source: Springer Online Journal Archives 1860-2000
    Topics: Natural Sciences in General , Technology
    Notes: Abstract This article examines 30 years of the National Science Foundation's experience in impacting on science and engineering education.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Pharmacy world & science 13 (1991), S. 109-118 
    ISSN: 1573-739X
    Keywords: Chemistry ; Consumer product safety ; Drug packaging ; Environmental pollution ; Plasticizers ; Polyvinyls
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract In this report the state of the art with respect to PVC as pharmaceutical packaging material is described. A general introduction into the applications of PVC is followed by a description of its production process. The metabolic effects of the monomer of PVC, vinyl chloride and of the most commonly used plasticizer diethylhexylphthalate are mentioned. Special attention is given to the pharmaceutical properties of plasticized PVC bags in comparison to other plastics and the environmental aspects of waste PVC disposal. Although there are emotional and political queries regarding the future use of PVC as a (pharmaceutical) packaging material, we conclude that there is no scientific justification for a total or partial ban of PVC. PVC will remain a fact of life as a cheap, versatile, high-performance and well-investigated plastic material for medical and pharmaceutical applications, to be replaced by newer plastics only for certain well-defined indications where the requirements of the plastic to be used are so specific that it will economically and technically be justified to use another polymer. Community and hospital pharmacists have to be prepared for a role in intake of waste plastic disposables, probably against deposit money, in order to fulfil the logistics needed for recycling.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-739X
    Keywords: Antimalarials ; Artemisia annua L ; Artemisinin ; Biosynthesis ; Chemistry ; Clinical trials ; Pharmacology ; Phytochemistry ; Sesquiterpenes ; Toxicology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Artemisinin, a sesquiterpene lactone endoperoxide isolated fromArtemisia annua L., and a number of its semisynthetic derivatives have shown to possess antimalarial properties. They are all eflective againstPlasmodium parasites that are resistant to the newest and commonly used antimalarial drugs. This article gives a survey of the literature dealing with artemisinin-relaled antimalarial issues that have appeared from the end of 1989 up to the beginning of 1994. A broad range of medical and pharmaceutical disciplines is covered, including phytochemical aspects like the selection of high-producing plants, analytical procedures, and plant biotechnology. Furthermore, the organic synthesis of artemisinin derivatives is discussed, as well as their mechanism of action and antimalarial activity, metabolism and pharmacokinetics, clinical studies, sideeffects and toxicology, and biological activities other than antimalarial activity.
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Chemometrics 5 (1991), S. 545-545 
    ISSN: 0886-9383
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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