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  • Mutation
  • American Association for the Advancement of Science (AAAS)  (5)
  • 1980-1984  (5)
  • 1981  (5)
Sammlung
Schlagwörter
Verlag/Herausgeber
  • American Association for the Advancement of Science (AAAS)  (5)
  • Springer  (2)
Erscheinungszeitraum
  • 1980-1984  (5)
Jahr
  • 1
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    Giant polytene chromosomes from the ovaries of a Drosophila mutant (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1981-04-24
    Beschreibung: The chromosomes of the ovarian nurse cells of Drosophila melanogaster fall apart during their cycles of endoreduplication. However, chromosomal synapsis occurs in the pseudonurse cells produced in certain mutant females. The resulting polytene chromosomes undergo developmental changes that are strikingly different from those recorded for the giant chromosomes of the larval salivary gland cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉King, R C -- Riley, S F -- Cassidy, J D -- White, P E -- Paik, Y K -- New York, N.Y. -- Science. 1981 Apr 24;212(4493):441-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6782674" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; Chromatin/ultrastructure ; Chromosome Inversion ; Chromosomes/*ultrastructure ; DNA Replication ; Drosophila melanogaster/*genetics ; Female ; Heterochromatin/ultrastructure ; Mutation ; Ovarian Neoplasms/genetics/veterinary ; Ovary/ultrastructure
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    Changes in DNA during meiosis in a repair-deficient mutant (rad 52) of yeast (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1981-05-01
    Beschreibung: The kinetic patterns of DNA synthesis in wild-type (RAD+) and rad 52 mutants of yeast, which exhibit high levels of synchrony during meiosis, are comparable. However, RAD 52 mutants accumulate single-strand breaks in parental DNA during the DNA synthesis period. Thus, the product of the RAD 52 gene has a role in meiotic DNA metabolism, as well as in the repair of DNA damage during mitotic growth. The observed breaks may be unresolved recombination intermediates.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Resnick, M A -- Kasimos, J N -- Game, J C -- Braun, R J -- Roth, R M -- 5 R01 GM17317-11/GM/NIGMS NIH HHS/ -- S07-RR07027/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 May 1;212(4494):543-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7010606" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): *DNA Repair ; DNA, Fungal/genetics ; DNA, Single-Stranded/genetics ; Genes ; *Meiosis ; Molecular Weight ; Mutation ; *Recombination, Genetic ; Saccharomyces cerevisiae/*genetics
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
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    Cyclophosphamide-induced spermatogenic effects detected in the F1 generation by behavioral testing (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1981-01-02
    Beschreibung: Fischer 344 male rats were treated with cyclophosphamide (10 milligrams per kilogram of body weight) for 5 weeks and subsequently mated to females previously treated with saline or cyclophosphamide. The F1 progeny of the cyclophosphamide-treated males exhibited behavior deficits when compared to controls. These data could indicate a chemically induced genetic effect manifested by behavioral alterations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Adams, P M -- Fabricant, J D -- Legator, M S -- New York, N.Y. -- Science. 1981 Jan 2;211(4477):80-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7444453" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; Avoidance Learning ; Behavior, Animal/*physiology ; Cyclophosphamide/*pharmacology ; Female ; Locomotion ; Male ; Motor Activity ; Mutation ; Rats ; Spermatogenesis/*drug effects
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
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    Suppressible four-base glycine and proline codons in yeast (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1981-04-24
    Beschreibung: Five ICR-170--induced mutations at the His4 locus in yeast are +1 G.C (G, guanine; C, cytosine) additions in DNA regions that contain multiple G.C base pairs. These mutations represents both nonsuppressible and suppressible alleles. All externally, suppressible frameshift mutations occur in glycine and proline codons to produce the four-base codons GGGU (U, uracil), GGGG, and CCCU. This implies that suppression of these four-base codons in yeast, as in bacteria, involves a four-base anticodon or its functional equivalent. Two identical four-base codons (CCCU) at widely separate regions with His4 are not suppressed equally.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Donahue, T F -- Farabaugh, P J -- Fink, G R -- New York, N.Y. -- Science. 1981 Apr 24;212(4493):455-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7010605" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Base Sequence ; *Codon ; DNA, Fungal/genetics ; Glycine/*genetics ; Histidine/genetics ; Mutation ; Proline/*genetics ; *RNA, Messenger ; Saccharomyces cerevisiae/*genetics ; *Suppression, Genetic
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
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    Germplasm conservation (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1981-12-04
    Beschreibung: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Russell, E S -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1074, 1076.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6946561" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; Cats ; Disease Models, Animal ; Dogs ; *Genetic Engineering ; *Genetics, Medical ; Humans ; Mice ; Mutation ; Rats
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
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