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  • 1
    Electronic Resource
    Electronic Resource
    On the survival probability of a slightly advantageous mutant gene with a general distribution of progeny size—A branching process model (1981)
    Springer
    Journal of mathematical biology 12 (1981), S. 355-362 
    Details
    ISSN: 1432-1416
    Keywords: Branching process ; Mutation ; Extinction ; Progeny size
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract A branching process method is employed to study the survival probability of a slightly advantageous mutant gene with a general distribution of progeny size in a large population. A counter-example to a classic proposition is given. A somewhat weaker result is proved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00276922
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  • 2
    Electronic Resource
    Electronic Resource
    Migration and mutation in stochastic models of gene frequency change. II. Stochastic migration with a finite number of islands (1981)
    Springer
    Journal of mathematical biology 13 (1981), S. 95-104 
    Details
    ISSN: 1432-1416
    Keywords: Stochastic migration ; Island model ; Mutation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Recurrence relations are derived for stochastic migration in the island model with a finite number of subpopulations. Two models are considered, one involving a constant probability that each individual breeding in a given colony has migrated from another, the other assuming the exchange of fixed numbers of migrants between colonies each generation. The equilibrium solutions are expressed in terms of two measures of genetic differentiation among subpopulations, one similar to Nei's measure of genetic distance, and the other closely related to the coefficient of kinship. Both measures are shown to be necessary for a complete description of population structure. The predictions of the models of stochastic migration are compared with the corresponding classical model of deterministic migration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00276868
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  • 3
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    Giant polytene chromosomes from the ovaries of a Drosophila mutant (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-04-24
    Description: The chromosomes of the ovarian nurse cells of Drosophila melanogaster fall apart during their cycles of endoreduplication. However, chromosomal synapsis occurs in the pseudonurse cells produced in certain mutant females. The resulting polytene chromosomes undergo developmental changes that are strikingly different from those recorded for the giant chromosomes of the larval salivary gland cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉King, R C -- Riley, S F -- Cassidy, J D -- White, P E -- Paik, Y K -- New York, N.Y. -- Science. 1981 Apr 24;212(4493):441-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6782674" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromatin/ultrastructure ; Chromosome Inversion ; Chromosomes/*ultrastructure ; DNA Replication ; Drosophila melanogaster/*genetics ; Female ; Heterochromatin/ultrastructure ; Mutation ; Ovarian Neoplasms/genetics/veterinary ; Ovary/ultrastructure
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Changes in DNA during meiosis in a repair-deficient mutant (rad 52) of yeast (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-01
    Description: The kinetic patterns of DNA synthesis in wild-type (RAD+) and rad 52 mutants of yeast, which exhibit high levels of synchrony during meiosis, are comparable. However, RAD 52 mutants accumulate single-strand breaks in parental DNA during the DNA synthesis period. Thus, the product of the RAD 52 gene has a role in meiotic DNA metabolism, as well as in the repair of DNA damage during mitotic growth. The observed breaks may be unresolved recombination intermediates.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Resnick, M A -- Kasimos, J N -- Game, J C -- Braun, R J -- Roth, R M -- 5 R01 GM17317-11/GM/NIGMS NIH HHS/ -- S07-RR07027/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1981 May 1;212(4494):543-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7010606" target="_blank"〉PubMed〈/a〉
    Keywords: *DNA Repair ; DNA, Fungal/genetics ; DNA, Single-Stranded/genetics ; Genes ; *Meiosis ; Molecular Weight ; Mutation ; *Recombination, Genetic ; Saccharomyces cerevisiae/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Cyclophosphamide-induced spermatogenic effects detected in the F1 generation by behavioral testing (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-01-02
    Description: Fischer 344 male rats were treated with cyclophosphamide (10 milligrams per kilogram of body weight) for 5 weeks and subsequently mated to females previously treated with saline or cyclophosphamide. The F1 progeny of the cyclophosphamide-treated males exhibited behavior deficits when compared to controls. These data could indicate a chemically induced genetic effect manifested by behavioral alterations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Adams, P M -- Fabricant, J D -- Legator, M S -- New York, N.Y. -- Science. 1981 Jan 2;211(4477):80-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7444453" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Avoidance Learning ; Behavior, Animal/*physiology ; Cyclophosphamide/*pharmacology ; Female ; Locomotion ; Male ; Motor Activity ; Mutation ; Rats ; Spermatogenesis/*drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Suppressible four-base glycine and proline codons in yeast (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-04-24
    Description: Five ICR-170--induced mutations at the His4 locus in yeast are +1 G.C (G, guanine; C, cytosine) additions in DNA regions that contain multiple G.C base pairs. These mutations represents both nonsuppressible and suppressible alleles. All externally, suppressible frameshift mutations occur in glycine and proline codons to produce the four-base codons GGGU (U, uracil), GGGG, and CCCU. This implies that suppression of these four-base codons in yeast, as in bacteria, involves a four-base anticodon or its functional equivalent. Two identical four-base codons (CCCU) at widely separate regions with His4 are not suppressed equally.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Donahue, T F -- Farabaugh, P J -- Fink, G R -- New York, N.Y. -- Science. 1981 Apr 24;212(4493):455-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7010605" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; *Codon ; DNA, Fungal/genetics ; Glycine/*genetics ; Histidine/genetics ; Mutation ; Proline/*genetics ; *RNA, Messenger ; Saccharomyces cerevisiae/*genetics ; *Suppression, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Germplasm conservation (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-12-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Russell, E S -- New York, N.Y. -- Science. 1981 Dec 4;214(4525):1074, 1076.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6946561" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Disease Models, Animal ; Dogs ; *Genetic Engineering ; *Genetics, Medical ; Humans ; Mice ; Mutation ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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