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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Pharmacology. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Pharmacology.
    Description / Table of Contents: Chapter 1. Botanical Features of Periwinkle, Catharanthus roseus -- Chapter 2. Catharanthus roseus: A Source of Anticancer Phytomedicines -- Chapter 3. Classical Breeding and Trait Genetics in Catharanthus -- Chapter 4. Somatic Embryogenesis in Catharanthus roseus: Proteomics of Embryogenic and Nonembryogenic Tissues; and Genome Size Analysis of Regenerated Plant -- Chapter 5. Alkaloid Synthesis in in vitro Cultures of Catharanthus roseus: Capabilities and Limitations -- Chapter 6. Genetic Transformation in Catharanthus roseus -- Chapter 7. Molecular Markers and Descriptor’s Suitable for Quantitative Trait Loci and Genome Mapping in Catharanthus roseus -- Chapter 8. Sequencing the Genome of Catharanthus roseus: Status and Prospects -- Chapter 9. Functional Genomics Approaches for Gene Discovery Related to Terpenoid Indole Alkaloid Biosynthetic Pathway in Catharanthus roseus -- Chapter 10. Future Prospects for Research on Catharanthus roseus.
    Abstract: This book is the first comprehensive compilation of deliberations on botany, medicinal importance, genetic diversity, classical genetics and breeding, in vitro biosynthesis, somatic embryogenesis, genetic transformation, molecular mapping, genome sequence, and functional genomics of Catharanthus roseus. Catharanthus is the most important medicinal plant in the world that contains about 130 therapeutic alkaloids out of which vinblastine and vincristine are the two highly used anticancer drugs sold by the pharmaceutically industries. Altogether, the book contains about 10 chapters authored by globally reputed experts on the relevant field of this plant. This book is useful to the students, teachers and scientists in the academia and relevant private companies interested in horticulture, genetics, breeding, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful to pharmaceutical industries.
    Type of Medium: Online Resource
    Pages: XXV, 183 p. 86 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030892692
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Economic Importance, Practical Limitations to Production, Management and Breeding Targets of Alfalfa -- Chapter 2. Factors Influencing Yield and Quality -- Chapter 3. The Origin, Evolution and Genetic Diversity of Alfalfa -- Chapter 4. Germplasm Collection, Genetic Resources and Gene Pools in Alfalfa -- Chapter 5. Biotechnology Advances in Alfalfa -- Chapter 6. Sequencing, Assembly and Annotation of the Alfalfa Genome -- Chapter 7. Transcription Factors in Alfalfa (Medicago sativa L.): Genome-Wide Identification and a Web Resource Center AlfalfaTFDB -- Chapter 8. Genomics of Forage Quality in Alfalfa -- Chapter 9. Physiological, Morphological, Biochemical, and Genetic Responses of Alfalfa to Salinity -- Chapter 10. Developing SNPs and Strategies for Genomic Analysis in Alfalfa -- Chapter 11. Genomics Resources for Breeding in Alfalfa: Availability, Utility, and Adoption -- Chapter 12. Genomic Selection for Higher Yield and Quality in Alfalfa -- Chapter 13. Identification and Characterization of Disease Resistance Genes in Alfalfa and Medicago truncatula for Breeding Improved Cultivars -- Chapter 14. Genetic and Genomic Assessments for Improving Drought Resilience in Alfalfa -- Chapter 15. Self-Incompatibility, Inbreeding Depression, and Potential to Develop Inbred Lines in Alfalfa -- Chapter 16. Targeted Mutagenesis of Alfalfa.
    Abstract: This book is the first comprehensive compilation of deliberations on whole genome sequencing of the diploid and tetraploid alfalfa genomes including sequence assembly, gene annotation, and comparative genomics with the model legume genome, functional genomics, and genomics of important agronomic characters. Other chapters describe the genetic diversity and germplasm collections of alfalfa, as well as development of genetic markers and genome-wide association and genomic selection for economical important traits, genome editing, genomics, and breeding targets to address current and future needs. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, breeding, pathology, physiology, molecular genetics and breeding, biotechnology, and structural and functional genomics. The work is also useful to seed and forage industries.
    Type of Medium: Online Resource
    Pages: XXV, 283 p. 64 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030744663
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 3
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    DDC: 615
    Language: English
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  • 4
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Abstract: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: IX, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649592
    DDC: 615
    Language: English
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  • 5
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. The Folklore Uses and Economic Importance of Some Selected Edible Medicinal, Plants Native to Oman. A Brief Review -- Chapter 2. Socio-economic Importance of Some Promising Edible Medicinal Plants from (Rajasthan) India -- Chapter 3. Traditional and Economic Valuation of Edible Plants Used for Treatment of Diabetes -- Chapter 4. Cultural and Socio-economic Perspective of Some Promising Edible Plants from Northern Pakistan -- Chapter 5. Medicinal Plants and their Contribution In Socio-Economic Upliftment of the Household in Gurez Valley (J&K) -- Chapter 6. Comprehensive overview of Some Edible Medicinal Plants from Kashmir Valley – Cultural, Economic and Pharmacological Importance -- Chapter 7. High Altitude Edible Plants: A Great Resource for Human Health and their Socio-economic Significance -- Chapter 8. Cultural, Practical and Socio-economic Importance of Edible Medicinal Plants Native to Central India -- Chapter 9. Cultural and Scio-economic Perspective of Some Promising Edible Plants from Uttarakhand Himalaya. Chapter 10. Edible Medicinal Plants from Chhattisgarh (India) and their Economic Significance -- Chapter 11. Ethno-botanical and Economic Significance of Edible Plants Used as Food by Tribal Community of the Western Himalaya -- Chapter 12. Cultural, Practical and Economic Value of Edible Plants used by Mizo Tribes of Mizoram -- Chapter 13. Isoflavones of Soy: Chemistry and Health Benefits -- Chapter 14. Account of Some Important Edible Medicinal Plants and their Socio-Economic Importance -- Chapter 15. Cultural, Practical and Economic Significance of Some Edible Medicinal Plants from Gilgit-Baltistan Pakistan.
    Abstract: The book provides significant information on some of the promising edible medicinal plants and how these possess both nutritive as well as medicinal value. The significance of these edible plants in traditional medicine, their distribution in different regions and the importance of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume focuses on the economic and culturally important medicinal uses of edible plants and a detailed survey of the literature on scientific researches of pharmacognostical characteristics, traditional uses, scientific validation, and phytochemical composition, and pharmacological activities. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits, as well as discussing how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists as well as all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: XI, 388 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811648809
    DDC: 615
    Language: English
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  • 6
    Keywords: Pharmacology. ; Epigenetics. ; Respiratory organs. ; Physiology. ; Pharmacology. ; Epigenetics. ; Respiratory Physiology.
    Description / Table of Contents: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Introduction to Epigenetics -- Chapter 3._Epigenetic mechanisms in Inflammation -- Chapter 4. Epigenetic regulator of inflammatory gene expression -- Chapter 5. Epigenetics of Asthma -- Chapter 6_. Epigenetic optimization in chronic obstructive pulmonary disease (COPD -- Chapter 7. Epigenetics of Lung Cancer -- Chapter 8. Epigenetics of Pulmonary Tuberculosis -- Chapter 9. Epigenetics of Idiopathic Pulmonary Fibrosis -- Chapter 10. Epigenetics of influenza-A virus infection -- Chapter 11. Epigenetics of rhinovirus -- Chapter 12. Epigenetics of SARS-Cov2 (Covid-19) -- Chapter 13. Epigenetics of Haemophilus Influenzae -- Chapter 14. Future Prospects and Challenges -- Chapter 15. Targeting epigenetics in pulmonary arterial hypertension.
    Abstract: This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.
    Type of Medium: Online Resource
    Pages: XV, 266 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819947805
    DDC: 615
    Language: English
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  • 7
    Keywords: Botany. ; Environment. ; Biotechnology. ; Renewable energy sources. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Plant Science. ; Environmental Sciences. ; Biotechnology. ; Renewable Energy. ; Fossil Fuel.
    Description / Table of Contents: Introduction: values of pollution free atmosphere -- Plant and Algae Classes Recognition, Biomass Production and Potential Source of Biofuel -- Plant and Algae Metabolites Alternative and Clean Source of Energy -- Mechanism and methods of extraction of biofuels -- Metabolic routes to biofuels extraction -- Optimizations on steps involved on biofuel obtainment and their validation -- Economic consideration on biofuel and energy security -- Technical challenges of biofuel obtainment -- Conclusion and Future Perspectives.
    Abstract: This volume discusses how plant and algae organisms play a pivotal role in the transformation of solar energy to essential metabolites, and explores the numerous beneficial roles these metabolites have at an industrial level. It presents information on the utilization of plant and algae for biomass production, and shows how this is a practical option for large scale biofuel production. The book examines how these bio-metabolites can then be used to extract biofuel. Biomass produced from plants and algae can act as the source of feedstock for biofuel production and industrially important compounds. This book also explores that by curtailing culturing cost using wastewater, seawater, and industrial water as a nutrient and water source, biomass becomes an economical energy source. The introductory chapters of the book focus on the appreciative values of a pollution-free atmosphere, with special reference to enhanced greenhouse effect, and then are followed by chapters on the potential of plant and algae as a liquid energy resource. This book targets researchers, graduate students, and energy and fuel industry professionals interested in the plant sciences, biotechnology and renewable energy. .
    Type of Medium: Online Resource
    Pages: XV, 164 p. 21 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030940744
    DDC: 580
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Environmental economics. ; Plant ecology. ; Economic geography. ; Environmental management. ; Plant Science. ; Environmental Economics. ; Plant Ecology. ; Economic Geography. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Introduction -- Chp 2: Amchur -- Chp.3:Anardana -- Chp 4:Balm or Lemon Balm -- Chp.5:Basil or Sweet Basil (Tulsi) -- Chp.6:Bay or Laurel Leaves -- Chp 7: Kokam or Kokum -- Chp 8:Juniper -- Chp.9: Hyssop -- Chp 10: Marjoram -- Chp 11: Japanese Mint -- Chp: 12: Peppermint -- Chp 13: Spearmint -- Chp 14. Origanum -- Chp 15: Parsley -- Chp 16: Rosemary -- Chp 17: Ashwagndha -- Chp 18.:Manathakkali.
    Abstract: This book discusses leafy spices or herbs known as “aromatic herbs”, which, apart from being used in culinary art for flavoring of foods and beverages, are also known to possess antiseptic, anti-oxidant and other medicinal properties, in addition to many nutraceutical and cosmetic properties. Of the numerous herbs twelve of the commercially important herbs are imported into 4 major European markets, namely, France, Germany, United Kingdom and The Netherlands to the tune of 12000 to 13000 tonnes per annum. This book discusses these leafy herbs and their tremendous commercial potential in international trade. The book offers a comprehensive insight into commercial herbs, with an objective of enhancing their yield, and provides a platform for further research into the global trade potential.
    Type of Medium: Online Resource
    Pages: XIV, 141 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031043604
    DDC: 580
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Food science. ; Plant ecology. ; Economic geography. ; Agriculture. ; Plant Science. ; Food Science. ; Plant Ecology. ; Economic Geography. ; Agriculture.
    Description / Table of Contents: Preface -- Chapter 1 Introduction -- Chapter 2 The Pepper Plant—Its Botany and Chemistry -- Chapter 3 Pepper Agronomy -- Chapter 4 The Role of the Nutrient Buffer Power Concept in Pepper Nutrition -- Chapter 5 Establishing a Pepper Plantation -- Chapter 6 Pepper Pests and Their Control -- Chapter 7 The Processing of Black Pepper on Farm -- Chapter 8 An Account of Indonesian Pepper Processing -- Chapter 9 Industrial Processing of Black Pepper -- Chapter 10 The Future of the Global Pepper Economy -- Chapter 11 Pepper Economy in India -- Chapter 12 Pepper Pharmacopoeia -- Chapter 13 Consumer Products Out of Black Pepper -- Chapter 14 Value Addition in Pepper -- Chapter 15 Conclusions and a Peep Into Pepper’s Future -- PRECISE QUANTIFICATION OF PLANT NUTRIENT BIO AVAILABILITY FOR BLACK PEPPER AND CARDAMOM -- TECHNOLOGICAL INNOVATIONS IN SPICES RESEARCH AND DEVELOPMENT!!!.
    Abstract: This book considers all aspects of black pepper from its growth, as a flowering vine, to how the dried fruit (peppercorn) is used as a spice and traded as a commodity. It is the economic mainstay of several India states and, principally, in Kerala State, with the Indian subcontinent being the largest black pepper producer. Indonesia has also emerged as a large producer of black pepper. Black pepper commands a leading position among the spices and has an immense commercial importance to world trade, finding its way onto the dining table of millions around the world, on the European and North American continents, and Japan. The use of black pepper ranges from a simple dietary component and flavour enhancer, to that of a spice with huge pharmacological benefits. .
    Type of Medium: Online Resource
    Pages: XIV, 162 p. 24 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030528652
    DDC: 580
    Language: English
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  • 10
    Keywords: Botany. ; Microbiology. ; Agriculture. ; Bioinformatics. ; Microbial ecology. ; Physical geography. ; Plant Science. ; Microbiology. ; Agriculture. ; Bioinformatics. ; Microbial Ecology. ; Earth System Sciences.
    Abstract: The third volume of the series ‘Bacilli and Agrobiotechnology’ is comprised of 25 chapters that bring a unique perspective to the readers about Bacillus-mediated biotic and abiotic plant stress tolerance, bioremediation and bioprospecting. These chapters are prepared by the leading scientists of global repute. The negative impacts of agrochemicals such as chemical fertilizers and pesticides on human health and environment are paramount. Bacillus and allied genera of beneficial plant-associated microbes are presenting beacon of hope to the farmers, plant scientists and stewards of environment. Several chapters of this volume focus on the induction of various signaling pathways in plants by Bacillus spp. to alleviate biotic and abiotic stresses impacted by global climate change Agricultural lands contaminated with heavy metals affect the ecological food chain starting from crop cultivation. How the toxic effects of trace metals originating from industrial effluents and agrochemicals can be remediated? This book addresses how to overcome these issues by applying elite strains of Bacillus. Bioprospecting is a systematic and organized search for conversion of bioresources to industrially important products by utilizing microbe-derived metabolites. This volume is enriched by including the bioprospecting aspects mediated by Bacillus spp. with novel insights.
    Type of Medium: Online Resource
    Pages: VII, 612 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030854652
    Series Statement: Bacilli in Climate Resilient Agriculture and Bioprospecting,
    DDC: 580
    Language: English
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  • 11
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    DDC: 615
    Language: English
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  • 12
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Botany. ; Agriculture. ; Biomolecules. ; Physical biochemistry. ; Macromolecules. ; Plant Science. ; Agriculture. ; Structural Biology.
    Description / Table of Contents: 1. Introduction -- 2. Floral morphology and phenology -- 3. Pollen grain morphology, viability, and insect visitation -- 4. The phenology of Rubus glaucus Benth. characterized by the BBCH scale -- 5.Propagation and cultivation -- 6.Fruit and chromosome number -- 7.Post-harvest physiology and nutritional facts -- 8.Genetic diversity -- 9.Breeding programs -- 10.Morphological diversity -- 11.Rubus glaucus and climate change.
    Abstract: The current book focuses on Mora de Castilla (Rubus glaucus Benth.). It explores aspects, such as origin, phenology, propagation, floral and fruit morphology, arthropod visitors, pollination mechanisms, propagation methods, chromosome number, fruit development, breeding, morphological diversity, and the impact of climate change. It includes novel data about plant phenology, flowering, insect visitors, seed germination, fruit morphology, and allometric relationships. This work includes an in-depth review of the most recently published information on the topic. Mora de Castilla is an economically important fruit crop from the Andes. It has been crossed with other Rubus species due to its high yield and everbearing habit. Currently, it is an economically important plant. It has been hybridized with other Rubus species producing new and better-quality hybrids This book contains numerous photographs selected by the author to provide the reader with detailed information about the plant´s morphological features and arthropod visitors. .
    Type of Medium: Online Resource
    Pages: XVIII, 178 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031317507
    DDC: 580
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Plant physiology. ; Botanical chemistry. ; Agriculture. ; Plant Science. ; Plant Physiology. ; Plant Biochemistry. ; Agriculture.
    Description / Table of Contents: Chapter 01: The Role of Gas Transmitters in Plant Hormonal Responses to Abiotic Stress -- Chapter 02: Understanding the involvement of gasotransmitters in the regulation of cellular signalling and adaptive responses against UV-B mediated oxidative stress in plants -- Chapter 03 Signaling Pathways of Gasotransmitters in Heavy Metal Stress Mitigation -- Chapter 04: Volatile signaling molecules in plants and their interplay with the redox balance under challenging environments: new insights -- Chapter 05: Alleviation of Plant Stress by Molecular Hydrogen -- Chapter 06: Understanding the role of nitric oxide and its interactive effects with phytohormones in mitigation of salinity stress -- Chapter 07 Nitric oxide – a small molecule with big impacts on plants under heavy metal stress -- Chapter 08: Nitric oxide: a key modulator of postharvest fruit and egetable physiology -- Chapter 09: Interaction of hydrogen sulfide with other phytohormones during physiological and stress conditions -- Chapter 10: Gasotransmitter hydrogen sulfide (H2S) and its role in plant development and defense responses -- Chapter 11 Hydrogen Sulfide (H2S) signaling in plants responding to abiotic stresses -- Chapter 12 Hydrogen sulfide metabolism and its role in regulating salt and drought stress in plants -- Chapter 13 Functional Roles of Hydrogen Sulphide in Postharvest Physiology of Fruit and Vegetables -- Chapter 14: Carbon compounds as gasotransmitters in plants under challenging environment -- Chapter 15: Carbon monoxide (CO) and its association with other gasotransmitters in root development, growth and signaling.
    Abstract: The book "Gasotransmitters Signaling in Plants under Challenging Environment" provides a comprehensive overview of the current state of knowledge on the role of gasotransmitters in plant stress responses. This edited volume delves deep into the captivating realm of gasotransmitters and their pivotal role in plant response to challenging environmental conditions. It brings together a wealth of cutting-edge research from around the world by leading experts in the field of gasotransmitter signaling in plants. Gasotransmitters, including nitric oxide, hydrogen sulfide, and carbon monoxide, have long been recognized as essential mediators of cellular signaling in animals. However, recent research has unveiled their incredible importance in orchestrating plant responses to environmental stresses. From drought and heat to pollution and pathogens, these tiny molecules serve as potent messengers, navigating plants through adversity and fostering their resilience in the face of an ever-changing world. As the world faces unprecedented environmental challenges, the knowledge presented in this book opens new avenues for sustainable agriculture and biotechnological interventions. The book provides an overview of the basic biology of gasotransmitters, including their production, metabolism, and signaling mechanisms. Further, it discusses the role of gasotransmitters in plant responses to specific abiotic stresses, such as drought, salinity, heavy metal toxicity, and high temperatures. The book also focuses on the potential applications of gasotransmitters in plant biotechnology. "Gasotransmitters Signaling in Plants under Challenging Environment" is an essential resource for researchers, students, and anyone interested in understanding the role of gasotransmitters in plant stress responses.
    Type of Medium: Online Resource
    Pages: VIII, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031430299
    Series Statement: Plant in Challenging Environments, 5
    DDC: 580
    Language: English
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  • 14
    Keywords: Botany. ; Plant ecology. ; Plant diseases. ; Plant Science. ; Plant Ecology. ; Plant Pathology.
    Description / Table of Contents: Ch 1. Plant invasion and climate change: a global overview -- Ch 2. Impacts of plant invasions on ecosystem functionality: a perspective for ecosystem health and ecosystem services -- Ch 3. Menace of Plant Invasion: A View from Ecological Lens -- Ch 4. Role of extreme climate events in amplification of plant invasion -- Ch 5. Plant Invasion as Gleaned from Parasara's Vrkshayurveda -- Ch 6. Water, wind, and fire: extreme climate events enhance the spread of invasive plants in sensitive North American ecosystems -- Ch 7. Understanding eco-geographical relationship in invaded ranges by Acacia longifolia (Andrews) Willd. – An intercontinental case study on Acacia invasions -- Ch 8. Invasive plants in India: their adaptability, socio-ecological impacts, and response to changing climate -- Ch 9. Plant invasion in an aquatic ecosystem: A new frontier under climate change -- Ch 10. Plant invasion and soil processes: A mechanistic understanding -- Ch 11. Plant invasion dynamics in mountain ecosystems under changing climate scenario -- Ch 12. The role of epigenetics on plant invasions under climate change scenario -- Ch 13. Comparative assessment of Machine Learning Algorithms for habitat suitability of Tribulus terrestris (Linn): An economically important weed -- Ch 14. Strategies of plant invasion and management for the conservation and restoration of degraded poor agricultural lands -- Ch 15. Plant Invasion and Climate Change: An Overview on History, Impacts and Management Practices -- Ch 16. Biochar: a tool for combatting both invasive species and climate change -- Ch 17. An action plan to prevent and manage alien plant invasions in India.
    Abstract: This edited book provides an ensemble of contemporary research related to the challenges, impacts and precautionary measures for tackling plant invasions in the context of changing climate in different regions of the world. In current scenario, plant invasions are expansive and significant component of anthropogenic global climate change. Temperature variations may compromise the adaptability of native species, thereby stressing them and decreasing the resistance potential of natural communities to invasion. Invasive alien species under the current scenario have been suggested as a major threat to biodiversity. It is also predicted that increasing disturbances or extreme events such as fires, floods, cyclones, storms, heat-waves, droughts, etc. will be direct consequences of changing climate supporting the invasive alien species. A comprehensive understanding of the interaction between species invasion and climate change will be supplemental in forecasting future shifts in biodiversity. Further, different predictive models indicate a plausible increase in the abundance and impact of invasive alien species which may have direct implications for future research and target-oriented policy and decision making. However, these predictions become more complicated considering the complexity of interactions between the impacts of changing climate with other components of global change (changes in land use, nitrogen deposition, etc.) which are affecting the distribution of native plant species, ecosystem dynamics as well as non-native/invasive species. This book will be suitable for students (undergraduate and postgraduates) of agriculture, forestry, ecology, soil science, and environmental sciences; teachers, researchers, and climate change scientists in academic and research institutions. It will also be applicable to environmental management agencies, government agencies and policy makers. .
    Type of Medium: Online Resource
    Pages: XVII, 418 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819959105
    DDC: 580
    Language: English
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  • 15
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Plant physiology. ; Plant diseases. ; Plant Science. ; Plant Physiology. ; Plant Pathology.
    Description / Table of Contents: Chapter 1 -- Root-knot Nematodes (Meloidogyne spp.), Chapter 2 -- Meloidogyne species: Threat to Vegetable Produce, Chapter 3 -- hemotaxis in Root-Knot Nematodes, Chapter 4 -- Phytohormone-Mediated Feeding Site Development, Chapter 5 -- 5. Current and Future Studies on the Genes for Parasitism in Meloidogyne, Chapter 6 -- Natural Product Repertoire for Suppressing the Immune Response of Meloidogyne species, Chapter 7 -- Epigenetic Mechanisms and their Role in Root Gall Formation,Chapter 8 -- Mass Spectrometry Imaging (MSI) and Root Gall Elucidation, Chapter 9 -- 9. Root-Knot Disease Complex: An Interactive Perspective with Microorganisms, Chapter 10 -- Breeding for Resistance in Vegetables against Meloidogyne species causing Root Gall Disease, Chapter 11 -- An Overview of Predacious Fungi for the Management of Root-knot Disease in Vegetables, Chapter 12 -- Biofertilizer of Organic Origin for Management of Root Galling Disease of Vegetables, Chapter 13 -- Prospects for the Use of Metabolomics Engineering in Exploring and Harnessing Chemical Signalling in Root Galls.
    Abstract: This book provides the most comprehensive and up-to-date review of research on vegetable plants associated with root-galls disease caused by root-knot nematodes (RKNs), Meloidogyne spp. Vegetables retain a key position in cultural cuisines and their consumption worldwide due to rich sources of micronutrients, including vitamins, minerals and antioxidants, but root galls disease of these crops caused by RKNs steals both quantity and quality from production. The field of plant nematology has experienced exponential growth over the past decade, and these RKNs are now known as widely damaging obligate plant parasites of vegetable plants. Advances are being made in understanding their biology, parasitism in the root system, giant cell development, root gall formation, chemical signalling, root-knot disease complexes, and management systems. This compilation provides an invaluable resource for studying root-galls disease of vegetable plants to those readers associated with plant nematology, plant pathology, plant protection, and agricultural science, including researchers, teachers, advanced undergraduates and graduate students, and even agricultural extension agents and farmers.
    Type of Medium: Online Resource
    Pages: XIX, 338 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938926
    DDC: 580
    Language: English
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  • 16
    Keywords: Botany. ; Human ecology Study and teaching. ; Plant Science. ; Environmental Studies.
    Description / Table of Contents: 1. Agronomic Biofortification- An Effective Tool for Alleviating Nutrient Deficiency in Plants and Human Diet -- 2. The Role of Biofortification in Enhancing Plant Growth, Development, Yield, and Quality -- 3. Improving Zinc Biofortification in Plants 4. Biofortification of Zinc: Uptake from the Soil and Transportation up to the Grains through ZIP Family Transporters -- 5. Mechanisms of Iron Uptake and Homeostasis in Plants: Implications for Biofortification in Cereal Grains -- 6. Selenium Biofortification in Agronomic Crops -- 7. Selenium Bio-fortification in Cereal Crops: An Overview -- 8. Nanoparticles Based Biofortification in Food Crops: Overview, Implications, and Prospects -- 9. Role of Nanoparticles in Improving Biofortification -- 10. Role of Nanoparticles in Improving Biofortification of Zinc and Iron in Vegetables -- 11. Scope of Seed Priming in Inducing Biofortification in Plants -- 12. Biofortification Through Seed Priming in Food Crops; Potential Benefits and Future Scope -- 13. Biochar for the Improvement of Crop Production -- 14. Phytohormones as Stress Mitigators in Plants.
    Abstract: This book provides a comprehensive summary of the recent advances in the biofortification of plants under climate change and how it affects food security globally. The need for mineral biofortification to eradicate or alleviate malnutrition through sustainable agriculture is also discussed. Biofortification of edible plants is considered the most appropriate approach to alleviate nutritional problems and nutrient deficiencies. In contrast, biofortification focuses on improving the nutritional content of the region's current agricultural biodiversity while preserving its habits and customs. Emphasis is also placed on recent advances and developments in omics, particularly metabolomics and related techniques, to unravel the potential alterations in plants caused by biofortification. The book brings together eminent scientists to present the latest developments in the field. This timely publication addresses practical scenarios of bio-fortified food production and climate change. The book focuses on the methods, techniques, and environmental changes used to enhance and improve agricultural products. This book is one of the first to provide information on the use of modern biotechnologies to modify crops for health benefits. It also examines the mechanisms of the plant responses to genetically induced biofortification, the production and responses of fortified plants under climate change, and their effects on food security. The book will be useful for students and researchers, especially crop scientists, environmental scientists, biotechnologists, botanists, and agronomists, to understand the techniques and mechanisms of biofortification, and responses of biofortified plants under climate change.
    Type of Medium: Online Resource
    Pages: XI, 338 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819940905
    DDC: 580
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Agriculture. ; Plant physiology. ; Plant Science. ; Agriculture. ; Plant Physiology.
    Description / Table of Contents: Introduction to MAPs in Turkey -- Ethnobotany in Turkey: Retrospect and Prospect -- Natural Dye Plants in Turkey -- Phytochemical and Biological Characteristics of Apiaceae (Umbelliferae) Species from Turkey.-The genus Salvia in Turkey: Morphology, Ecology, Phytogeograpy, Endemism and Threat Categories -- Threatened Medicinal and Aromatic Plants and Conservation Studies in Turkey -- Cultivation and Breeding of MAPs in Turkey -- Traditional Uses and Cultivation of St. John’s Wort (Hypericum perforatum L.) in Türkiye -- Turkish Oregano (Origanum spp.) – Biodiversity, Cultivation, Traditional & Commercial Uses -- Traditional Medicinal and Aromatic Trees in Turkiye: Laurel (Laurus nobilis), Sumac (Rhuscoriaria), Hawthorn (Crataegus spp.) and Carob (Ceratonia siliqua) -- Turkish Soaproot (Radix gypsophylae) -- Traditional Farming of Apiaceae Species in Turkiye: Pimpinella anisum L., Foeniculum vulgare Mill., Cuminum cyminum L.) -- Traditional Uses of Turkish Asteraceae Species -- Anti-aging effect of Turkish medicinal plants on skin: Focus on recent studies.
    Abstract: This is meant to be the 10th volume of the series Medicinal and Aromatic Plants of the World. Similarly, to the previous volumes, the work will deal -in a monographic form- with MAPs characteristic/famous or simply known of Turkey, a large country that is connecting Europe with Asia. Turkey has extremely rich and varied topographic/ecologic conditions. As a result, the flora of Turkey abounds in an astonishingly great number of endemic MAP species. Traditional, present and possible prospective uses will be discussed. Scientific and technological achievements will be equally presented. Briefly, the volume is aimed to look carefully at our present knowledge of this vast interdisciplinary domain of medicinal and aromatic plants with a focus on Turkey. In the era of global climate change and Covid-pandemics, building on the huge Turkish traditions, the proposed volume of the series is expected to make an important contribution to the better knowledge and understanding of the MAP wealth of the World.
    Type of Medium: Online Resource
    Pages: X, 327 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031433122
    Series Statement: Medicinal and Aromatic Plants of the World, 10
    DDC: 580
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Agriculture. ; Plant diseases. ; Plant Science. ; Agriculture. ; Plant Pathology.
    Description / Table of Contents: 1. Medicinal and Aromatic Plants in India: A bridge from Traditions to modern wellbeing -- 2. Holy basil (Ocimum sanctum L.) - an important indian medicinal and aromatic plant: its properties, utilization and genetic improvement -- 3. Ethnomedicinal Importance of Common Weeds of the Family Asteraceae in the Tribal Belt of Rajasthan, India -- 4. Cydonia oblonga Mill. - Wound healing properties -- 5. Artemisia annua L. - A comprehensive review on pharmacological properties -- 6. Mesua ferrea L - Ethnobotany, Phytochemistry and Pharmacology -- 7. Linum usitatissimum L. - Rich store house of pharmacologically active metabolites -- 8. Gymnema sylvestre R.Br.: - Phytochemicals and Medicinal Properties -- 9. Medicinal and Aromatic plants of India used in the treatment of skin disorders -- 10. Traditional uses and properties of Indian medicinal plants in the treatment of Vitiligo -- 11. Indian MAPs with hepato-protectant potentials -- 12. Selected Medicinal Plants for Treatment of Mucormycosis, in India -- 13. Selected Indian Medicinal And Aromatic Plants For Prophylactic Therapy -- 14. Conservation Strategies Of Indian Medicinal Plants.
    Abstract: This book is the 9th volume in the series Medicinal and Aromatic Plants of the World. India being one of the countries with the longest and richest past/present/future of Medicinal and Aromatic Plant (MAP) production and utilization has accumulated more than sufficient knowledge to fill two volumes. This is shown by the vivid interest of Indian colleagues to contribute. Similar to the previous volumes, this one deals with the various important aspects (from botanical through phytochemical to pharmacological) of MAPs', famous or simply known of India. Scientific and technological achievements will be equally presented. In addition to the first volume, India V1, this volume is aimed to look carefully at our present knowledge of this vas interdisciplinary domain with an Indian focus. In the era of global climate change and pandemics, building on the huge Indian traditions, this book is expected to make an important contribution to the better knowledge and understanding of MAPs.
    Type of Medium: Online Resource
    Pages: X, 302 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031449147
    Series Statement: Medicinal and Aromatic Plants of the World, 9
    DDC: 580
    Language: English
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  • 19
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Pharmacology. ; Pharmaceutics. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1: Radiation biology: historical background, sources and complications -- Chapter 2: Algal radioprotective phytochemicals: Sources and potential applications -- Chapter 3: Bio-prospecting of photoprotective compounds in algae -- Chapter 4: Unraveling fungal radioprotectants and their applications -- Chapter 5: Recent advances in metabolomics and molecular genomics for the production of photoprotective compounds -- Chapter 6: Bioprospecting and evolutionary significance of radioprotectors in non-flowering lower plants -- Chapter 7: Radioprotective phytochemicals: diversity, efficacy, application and commercialization -- Chapter 8: Impacts of climate alterations in the biosynthesis of defensive natural products -- Chapter 9: Cancer therapeutics: mechanism of action, radiation toxicity and drug formulation -- Chapter 10: Role of nanotechnology in the development of radioprotective formulations -- Chapter 11: Radioprotective effects of nutraceuticals and food products -- Chapter 12: Bioprospecting of radioprotective compounds in bacterial community -- Chapter 13: Pharmacology of synthetic and natural radioprotactants: application and consequences in cancer therapeutics -- Chapter 14: Immunochemistry: consequences and mechanism of protection in chemotherapeutics -- Chapter 15: Radioprootective therapeutics: recent trends and future applications.
    Abstract: This book illustrates the role of photoprotective and radioprotective metabolites from natural sources. Various classes of radioprotective metabolites derived from cyanobacteria, algae, fungi, bryophytes, pteridophytes, gymnosperms, and higher plants have been explained to reinforce the current knowledge in this field. In addition, the book elucidates the potential applications of these metabolites in pharmaceutics, cosmetics, and biomedical sciences that will help develop commercial products in modern anti-radiation therapeutics. Topics such as stress tolerance environmental strategies, evolutionary tendency, and biosynthetic route of radioprotective compounds for cost-effective large-scale industrial production of the metabolites are also covered in the book. This book will add to the understanding of radioprotective mechanisms and curative measures for various deleterious diseases leading to cancer development. This volume also offers the latest insights into current and upcoming issues that arise from solar and atomic radiations and their amelioration by inherent radioprotective mechanisms of green plants. This book benefits readers from academia, industry, colleges, and research students to better understand the impacts of various radiations and the development of radioprotective green compounds.
    Type of Medium: Online Resource
    Pages: XIII, 264 p. 62 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819907496
    DDC: 615
    Language: English
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  • 20
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Immunology. ; Neurology . ; Endocrinology. ; Cardiology. ; Pharmacology. ; Immunology. ; Neurology. ; Endocrinology. ; Cardiology.
    Description / Table of Contents: Part 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer’s disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
    Abstract: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031426483
    Series Statement: Handbook of Experimental Pharmacology, 282
    DDC: 615
    Language: English
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  • 21
    Keywords: Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Abstract: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Type of Medium: Online Resource
    Pages: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581274
    DDC: 615
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. The Broomcorn Millet Genome -- Chapter 2. Buckwheat Genome and Genomics -- Chapter 3. Tef [Eragrostistis tef (Zucc.) Trotter] -- Chapter 4. The Apricot Genome -- Chapter 5. Chinese Jujube: Crop Background and Genome Sequencing -- Chapter 6. The Longan (Dimocarpus longan) Genome -- Chapter 7. The Mangosteen Genome -- Chapter 8. The Passion Fruit Genome -- Chapter 9. The Soursop Genome (Annona muricata L., Annonaceae) -- Chapter 10. Underutilised Fruit Tree Genomes from Indonesia -- Chapter 11. The Bambara Groundnut Genome: From the Crop to the Genome -- Chapter 12. Grasspea -- Chapter 13. The Lablab Genome -- Chapter 14. The Perennial Horse Gram (Macrotyloma axillare) Genome, Phylogeny, and Selection Across the Fabaceae -- Chapter 15. Breeding and Genomics of Pigeonpea in the Post-NGS Era -- Chapter 16. Rice Bean -- Chapter 17. The Winged Bean Genome: One Species Supermarket -- Chapter 18. Castor Bean: Recent Progress in Understanding the Genome of this Underutilized Crop -- Chapter 19. Genome Resources for Ensete Ventricosum (enset) and Related Species -- Chapter 20. Yam Genomics -- Chapter 21. The African Eggplant -- Chapter 22. Sequencing of the Bottle Gourd Genomes Enhances Understanding of the Ancient Orphan Crop -- Chapter 23. Advances and Prospects in Genomic and Functional Studies of the Aquatic Crop, Sacred Lotus -- Chapter 24. Utilising Public Resources for Fundamental Work in Underutilised and Orphan Crops.
    Abstract: This book highlights the uses for underutilized crops, presenting the state-of-the-art in terms of genome sequencing for over 30 crops, previously understudied and under-researched. In a changing climate and with significant pressure on the land, it is the ideal time to be discussing novel crops, with significant biotic and abiotic tolerances and/or rich nutrient profiles for consumers. Previously, the only species with sequenced genomes were high-profile internationally recognized crops, but in the current era genomes are being sequenced for dozens of crops, including those previously classified as underutilized, now being investigated. This book covers food crops, from fruits to tubers, and from grasses to legumes, as well as crops with non-food applications. Some of these crops have draft genomes, and others have polished genomes with extensive resequencing panels. Each chapter tells the story of an individual crop or crop group, written by experts, focusing on the genome data available, revealing more about crop domestication and genetic variation, and the current and future prospects given that this data is now becoming available. It also highlights how even small sequencing projects can provide draft genome sequences suitable for gene discovery, comparative genomics, and identification of molecular markers for understanding these crops further.
    Type of Medium: Online Resource
    Pages: XXIV, 450 p. 125 illus., 105 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031008481
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 23
    Keywords: Botany. ; Biodiversity. ; Plant ecology. ; Conservation biology. ; Ecology . ; Plant Science. ; Biodiversity. ; Plant Ecology. ; Conservation Biology.
    Description / Table of Contents: Flowering phenology in a restinga community: seven years of study -- Dioecy: the dimorphic sexual system and pollination in restinga vegetation -- Male and female sterility in flowering plants -- Broad-scale variation of phytoplankton richness in Brazilian inland waters -- The Importance of Palynology to Taxonomy -- Ecological Palynology -- Scientific Exploration Commission (1859-1861): Freire Allemão and the invisible network of collaborators -- The former Imperial Plant Nursery of Quinta da Boa Vista -- Medicinal plants used in Quilombola communities in Piranga, State of Minas Gerais, Brazil -- From mulungu to mamulengo”: The sharing of knowledge among teachers, academic researchers and mamulengueiros (traditional puppeteers) in a participatory workshop -- Biocultural heritage through museological narrative as a way of return on research in historical ethnobotany -- Conclusion of the reflections on Aspects of Brazilian Floristic Diversity: From Botany to Traditional Communities.
    Abstract: Aspects of Brazilian Floristic Diversity: From Botany to Traditional Communities offers a unique approach in floristic diversity of the Neotropical region, specifically encompassing the Brazilian flora. This volume combines both theoretical and applied aspects of scientific making knowledge in different perspectives of Botanical Science. In this volume, botanical specialists discuss the many different approaches of taxonomic, reproductive, ecological and ethnobotanical aspects of Brazilian floristic diversity, thereby enlightening the global interest in Neotropical species, in particular those from the Brazilian territory. The book addresses relevant questions from many points of view, including anatomy, reproduction, palinology, conservation and ethnobotany, creating an in-depth perception of the flora in its complexity constitution. The book provides a comprehensive outlook on Botany Sciences, considering the history and traditional knowledge of plants, and relating it to contemporary problems and concerns of flora conservation today. With this current perspective, this book reaches a vast audience from the research lines of Botany, and encompasses a broader and interdisciplinary understanding of Aspects of Brazilian Floristic Diversity.
    Type of Medium: Online Resource
    Pages: XXIV, 268 p. 49 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031074530
    DDC: 580
    Language: English
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  • 24
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Agriculture. ; Genetics. ; Plant Science. ; Agriculture. ; Genetics and Genomics.
    Description / Table of Contents: 1. Introduction -- 2. Taxonomy and Evolution of the tribe Triticeae Dumort -- 3. Genome structure of Triticeae species -- 4. B Chromosomes -- 5. Orphan genera of the subtribe Triticineae Simmonds -- 6. Secale L -- 7. Classification of the wheat group (the genera Amblyopyrum, Aegilops, and Triticum) -- 8. Amblyopyrum (Jaub. &Spach) Eig -- 9. Aegilops L -- 10. Triticum L. -- 11. Evolution of the diploid species of the sub-tribe Triticineae -- 12. Evolution of the allopolyploid species -- 13. Evolution of wheat under cultivation -- 14. Future prospects -- 15. References. .
    Abstract: This open access book covers a century of research on wheat genetics and evolution, starting with the discovery in 1918 of the accurate number of chromosomes in wheat. We re-evaluate classical studies that are pillars of the current knowledge in light of recent genomic data in the wheat group comprising 31 species from the genera Amblyopyrum, Aegilops, Triticum, and other more distant relatives. For these species, we describe morphology, ecogeographical distribution, phylogeny as well as cytogenetic and genomic features. For crops, we also address evolution under human selection, namely pre-domestication cultivation and domestication. We re-examine the genetic and archeological evidence of where, when, and how domestication occurred. Several species are polyploids, including bread wheat which is a young allohexaploid. We discuss unique aspects of genome evolution and maintenance under polyploidization. Finally, we propose some thoughts on the future prospects of wheat improvement. As such, it can be of great interest to wheat researchers and breeders as well as to plant scientists and students interested in plant genetics, evolution, domestication, and polyploidy.
    Type of Medium: Online Resource
    Pages: XXIII, 673 p. 28 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031301759
    DDC: 580
    Language: English
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  • 25
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Preface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson’s Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging.
    Abstract: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031230585
    Series Statement: Current Topics in Behavioral Neurosciences, 60
    DDC: 615
    Language: English
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  • 26
    Keywords: Botany. ; Plant diseases. ; Agriculture. ; Plant Science. ; Plant Pathology. ; Agriculture.
    Description / Table of Contents: Part 1. Organic Management of Nematodes: Paradigms and Mechanisms -- 1. Biochemical Biopesticides for Phytonematode Sustainable Management: Status and Future Prospects (Thales Lima Rocha; Vera Lucia Perussi Polez; Lívia Cristina de Souza Viol; Reinaldo Rodrigues Pimentel, Danielle Biscaia; Jadir Borges Pinheiro) -- 2. Organic Nematicides: A Green Technique and its Overview for the Nematode Disease Management (Faryad Khan, Mohammad Shariq, Mohd Asif, Taruba Ansari, Saba Fatima, Arshad Khan, Mohd Ikram, Mansoor Ahmad Siddiqui) -- 3. Nematode Management Through Compost (Fisayo Yemisi Daramola, Samuel B. Orisajo and Omorefosa Osarenkhoe Osemwegie) -- 4. Biochemical/Molecular Mechanisms Associated with Nematode Management Through Organic Amendments: A critical Review (John Fosu-Nyarko, Rhys G. R. Copeland, Sadia Iqbal, Michael G. K. Jones) -- 5. Organic By-Products in the Suppression of Plant-Parasitic Nematodes (Alixelhe Pacheco Damascena, Marylia Gabriella Silva Costa, Júlio César Antunes Ferreira, Silvia Renata Siciliano Wilcken) -- 6. Nematode Management by Humic Acid (Seenivasan Nagachandrabosea, Sankaranarayanan Chellappab, and Devrajan Kandasamya) -- 7. Conventional and Organic Management as Divergent Drivers for Plant Parasitic Nematodes (PPNs) control (Kanika Khanna, Vandana Gautam, Dhriti Kapoor, Nandni Sharma, Pooja Sharma, Tamanna Bhardwaj, Puja Ohri, Renu Bhardwaj) -- Part 2. Organic Management of Nematodes: Global Case studies and Success Stories -- 8. Plant Extracts and Their Effect on Plant-parasitic nematodes: Case Studies from Africa (Ebrahim Shokoohi) -- 9. Organic Management of the Citrus, Pine and Related Nematodes (Reza Ghaderi, Manouchehr Hosseinvand) -- 10. Organic Management of Rice Root-Knot Nematode Meloidogyne graminicola (Ziaul Haque and Mujeebur Rahman Khan) -- 11. Strategies for the Organic Management of the Root-Knot Nematode (Meloidogyne spp.) in Grapevine Under Desert Conditions in the North Coast of Peru (César Augusto Murguía Reyes) -- 12. Organic Fumigant Alternatives for Nematode Management in High-Value Crops in Florida (Johan Desaeger, Kaydene Williams, and Erin Rosskopf) -- 13. The False Root-Knot Nematode Nacobbus aberrans and its Ecological Management (Edgar Villar-Luna, Olga Gómez-Rodríguez, Hernán Villar-Luna, Liliana Aguilar-Marcelino, Laith Khalil Tawfeeq Al-Ani, and Ernesto Fernández-Herrera) -- 14. Plant Extracts, Sorghum and Crucifers Amendments and Pochonia chlamydosporia for the Management of Meloidodyne spp. and Nacobbus aberrans in Tomato and Chile Crops: the Mexican Experience (Ignacio Cid del Prado-Vera, Marco Antonio Magallanes-Tapia, Raúl Velasco-Azorsa, Arely Pérez-Espíndola) -- 15. Non-Conventional Management of Plant-Parasitic Nematodes in Musaceas Crops (Donald Riascos–Ortiz, Ana Teresa Mosquera–Espinosa, Francia Varón De Agudelo, Claudio Marcelo Gonçalves De Oliveira, Jaime Eduardo Muñoz–Florez) -- 16. Neem Cake Amendment Changes Soil Nematode Spatio-temporal Dynamics Across a Guava Orchard in the Brazilian Semiarid Region (Diego Arruda Huggins de Sá Leitão, Ana Karina dos Santos Oliveira, Douglas Barbosa Castro, Elvira Maria Régis Pedrosa).
    Abstract: The present work covers many aspects of plant nematode management using organic strategies. These range from applications of latest understandings of fundamental concepts/mechanisms of nematode control, to modern tools and techniques used in efficacy evaluation. The Volume also includes some case studies/applied aspects of organic nematode pest management. Chemical and physical control measures used for nematode management have their own implications. Against this backdrop, organic management of plant nematodes appears as a more rational and sustainable approach. However, concise information on the current topic is scarce. This book is a sincere effort to bridge this void as we aim to provide the most updated, critical and in-depth knowledge synthesized by many experts working in the field of plant nematology, worldwide.
    Type of Medium: Online Resource
    Pages: XI, 440 p. 51 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031099434
    Series Statement: Sustainability in Plant and Crop Protection, 18
    DDC: 580
    Language: English
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  • 27
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Biodiversity. ; Plant biotechnology. ; Plant Science. ; Biodiversity. ; Plant Biotechnology.
    Description / Table of Contents: 1. The Current Status of Population Extinction and Biodiversity Crisis of Medicinal Plants -- 2. Medicinal Plants and Bioactive Phytochemical Diversity: A Fountainhead of Potential Drugs against Human Diseases -- 3. Threats and opportunities for sustainable use of medicinal plants in Brazilian Atlantic Forest based on the knowledge of Indigenous Peoples and Local Communities -- 4. Climate Change Impact on Medicinal Plants: An Insight from the IUCN Red List Of Threatened Species -- 5. Securing Conservation Status of Paris Polyphylla, a Medicinally Important Plant of the Indian Himalayan Region -- 6. Endophytic Fungal Diversity in Solanaceous Medicinal Plants and Their Beneficial Impact -- 7. Genetic Studies on Threatened Medicinal Plants of Brazil: Mind the Gap -- 8. Medicinal Plants of North-east India: Biodiversity and Their Ethno-Medicinal Values -- 9. Strategies for Conservation and Sustainable Use of Medicinal Plants -- 10. Scientific Databases for Conservation of Medicinal Plants -- 11. International Trade of Medicinal and Aromatic Plants (MAPs) -- 12. Inventorization of Ecology, Ethnobotany and Conservation Status of Dactylorhiza hatagirea: Problems Progress and Prospects -- 13. Conservation and Sustainable Use of Medicinal Plants -- 14. Traditional Practices of Ethnomedicinal Plants in North-East Region of India and Their Conservation for Sustainable Utilization -- 15. Occurrence and Diversity of Major Naphthoquinones in Higher Plants: Their Distribution and Conservation Strategies -- 16. Astragalus fridae genetic Source,Applications, and Conservation -- 17. Tinospora cordifolia as a Potential Candidate for Health Care Of Post-Menopausal Women -- 18. The Potential Role of Medicinal Plants, Traditional Herbal Medicines and Formulations to Overcome SARS-CoV-2 Induced Health Crisis -- 19. Bioactive Compounds from Medicinal Plants and Its Therapeutic Uses in the Traditional Health Care System -- 20. In-Vitro conservation and propagation of endangered Ethno-Medicinal Orchids from the Northeast Region of India -- 21. Artificial Seed Production and Cryopreservation Technology for Conservation of Plant Germplasm with Special Reference to Medicinal Plants -- 22. Biotechnological Studies on Nasturtium Officinale (Watercress) - An Endangered Species of Significant Relevance in Medicine, Cosmetic, and Food Industries -- 23. Isatis tinctoria L. (woad) – Cultivation, Phytochemistry, Pharmacology, Biotechnology, and Utilization -- 24. Tissue Culture Techniques to Conserve Endangered Medicinal Plants with Antimicrobial and Antiviral Activities -- 25. Insights into the In Vitro Approaches for the Production of Secondary Metabolites Towards The Conservation of Medicinal Orchids -- 26. Biotechnological Approaches for Ex Situ Conservation of Medicinal Plants -- 27. Conservation of Medicinal Plants by Tissue Culture Techniques -- 28. Current Status of Metabolic Engineering of Medicinal Plants for Production of Plant-derived Secondary Metabolites -- 29. Stationary, Agitated and Bioreactor Cultures of Verbena officinalis L. (Common Vervain) - A Potential Rich Source of Bioactive Phenolic Compounds for Pharmacy, Health Food Industry and Cosmetology.
    Abstract: This contributed volume provides a comprehensive, in-depth and subject-based reviews on the current status of active ingredients, sustainable use, biodiversity and conservation of certain endangered medicinal plants. The book also explores conventional and non-conventional biotechnological interventions for their biodiversity conservation. Medicinal plants have been used in worldwide as a major source of raw material for the traditional herbal healthcare practices as well as for drug discovery and development in pharmaceutical industry. The cumulative consequences of various human activities and environmental factors cause decline in the biodiversity of medicinal plants at an unprecedented rate worldwide. Thus, the overall understanding of ecology, species and genetic diversity along with assessment of the status of different threats and their impact on medicinal plants is crucial to sustain existing biodiversity, its utilization and conservation. All the latest advancements in the biotechnological approaches for the conservation research of endangered medicinal plants and the future perspectives have been described. This book provides comprehensive reviews spreading over about 25 chapters divided in three sections. The chapters of this book are written by recognized scientists in their respective fields which are useful to students, academicians, researchers, botanists, biotechnologists, policy makers, conservationists and industries interested in biodiversity conservation and medicinal plant research for the production of secondary metabolites.
    Type of Medium: Online Resource
    Pages: XIX, 906 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811999369
    Series Statement: Sustainable Development and Biodiversity, 33
    DDC: 580
    Language: English
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  • 28
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    DDC: 615
    Language: English
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  • 29
    Keywords: Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Description / Table of Contents: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Abstract: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Type of Medium: Online Resource
    Pages: IX, 590 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936649
    DDC: 615
    Language: English
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  • 30
    Keywords: Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Abstract: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951251
    DDC: 615
    Language: English
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  • 31
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Internal medicine. ; Cancer. ; Pharmacology. ; Internal Medicine. ; Cancer Biology.
    Description / Table of Contents: Part 1. Pharmacogenomics -- Building evidence in RCTs Implementation of pharmacogenomics in healthcare in the UK -- Part 2. Precision medicine in clinical entities -- Precision medicine in therapy of non-solid cancer -- Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia -- Precision medicine in Asthma -- Precision medicine in Diabetes -- Precision Medicine in Antidepressants Treatment -- Precision Medicine in Neuropathic Pain -- Part 3. Techniques in Precision Medicine -- Imaging techniques in pharmacological precision medicine -- Challenges to use NGS data to optimize drug therapy -- Part 4. Economics -- Pharmacoeconomics in precision medicine. .
    Abstract: The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers including pharmacogenomics as well as advanced diagnostic tools have been successfully implemented in clinical practice in various fields leading to significant improvement of treatment successes. This volume gives an up-to-date overview on applications of precision medicine in various clinical entities, on advanced techniques as well as on economic considerations.
    Type of Medium: Online Resource
    Pages: X, 283 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031400476
    Series Statement: Handbook of Experimental Pharmacology, 280
    DDC: 615
    Language: English
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  • 32
    Keywords: Botany. ; Plants. ; Botanical chemistry. ; Stress (Physiology). ; Plant Science. ; Plant Signalling. ; Plant Biochemistry. ; Plant Stress Responses.
    Description / Table of Contents: Preface -- I. Melatonin as an antioxidant -- Chapter 1. Melatonin and the metabolism of reactive oxygen species (ROS) in higher plants -- II. Melatonin, biosynthesis, plant growth, development and reproduction -- Chapter 2. Melatonin in Plants: Biosynthesis, Occurrence and Role in plants -- Chapter 3. Abiotic stress-induced modulation of melatonin biosynthesis accompanying phytohormonal crosstalk in plants -- Chapter 4. Role of melatonin in embryo, seed development and germination -- Chapter 5. Melatonin metabolism in seeds: physiological and nutritive aspects -- Chapter 6. Melatonin in plant growth and signaling -- Chapter 7. Functions and prospects of melatonin during pre-fertilization reproductive stages in plants -- Chapter 8. Melatonin and fruit ripening physiology: crosstalk with ethylene, nitric oxide, hydrogen peroxide and hydrogen sulfide -- Chapter 9. Melatonin and postharvest biology of fruits and vegetables: augmenting the endogenous molecule by exogenous application -- Chapter 10. Melatonin language in postharvest life of horticultural crops -- III. Melatonin and its signaling in biotic and abiotic stress -- Chapter 11. Melatonin-mediated regulation of biotic stress responses in plants -- Chapter 12. Emerging roles of melatonin in mitigating pathogen stress -- Chapter 13. Eco-physiological and morphological adaptive mechanisms induced by melatonin and hydrogen sulfide under abiotic stresses in plants -- Chapter 14. Melatonin in plants under UV stress conditions -- Chapter 15. Molecular physiology of melatonin induced temperature stress tolerance in plants -- Chapter 16. Melatonin-mediated salt tolerance in plants -- Chapter 17. Role of phytomelatonin in promoting ion homeostasis during salt stress -- Chapter 18. Positive regulatory role of melatonin in conferring drought resistance to plants -- Chapter 19. Potential, mechanism and molecular insight of melatonin in phytoremediation.
    Abstract: The new edited volume on phytomelatonin and its diverse roles in plants under a challenging environment shall be an important reference book with updated information and future perspectives on the involvement of this biomolecule in stress resilience in plants. Investigations on different aspects of melatonin in plants have undergone a prolific surge in the last decade. In view of such a considerable volume of investigations in melatonin, the proposed new volume will collate its role in different aspects of plants signaling, growth and metabolism. In this context, it has been important to understand its function as a stress priming molecule that executes associative synergistic relation with various other plant growth regulators (viz. nitric oxide, hydrogen sulfide, inorganic ions, and enzymes). Thus, crop management under diverse stressful environments can be better achieved by elucidating our current understanding of the role of melatonin and its interplay with various plant metabolites. The book shall provide a collation of recent advancements in genomic, transcriptomic, and metabolomic approaches to decipher the molecular mechanisms of melatonin signaling and its agronomic importance in plants. .
    Type of Medium: Online Resource
    Pages: IX, 386 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031401732
    Series Statement: Plant in Challenging Environments, 4
    DDC: 580
    Language: English
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  • 33
    Keywords: Botany. ; Agriculture Economic aspects. ; Alternative medicine. ; Pharmacology. ; Agronomy. ; Agriculture. ; Plant Science. ; Agricultural Economics. ; Complementary and Alternative Medicine. ; Pharmacology. ; Agronomy. ; Agriculture.
    Description / Table of Contents: 1. Khikeya Semy*, Ruokuonuo Kuotsu -- Ethnobotanical study of medicinal herbs used by the Naga tribals of Eastern Himalayas -- khikeyasemy@gmail.com -- 2. Ahirrao YA1, Patil MV2 and DA Patil3* -- Ethnomedicinal Use-reports of Seeds As Tapped From Herbal Vendors In North Maharashtra (India) -- dapatil_10aug@yahoo.com -- 3. Pious Soris Tresina, Murugeswaran Santhiya Selvam, Vallinayagam Sornalakshmi and Veerababu Ramasamy Mohan -- Ethnobotanical Study of Medicinal Plants Used by Traditional Healers in Grizzled Squirrel Wildlife Sanctuary -- vrmohanvoc@gmail.com -- 4. Jayalekshmi C V 1† , Reshma K Ramesh 1† , Vijai M 2† & Suresh V* -- Ethnomedicinal Plants used by Irula Tribal Settlement of Attappady in Palakkad District Kerala, India -- 5. Jayalekshmi C V 1† , Reshma S 2† & Suresh V* -- Folk Medicine Of Chittur Taluk In Palakkad District, -- 6. R. Manikandan 1 , S.P. Nithya, R. Mehala Devi -- Checklist Flora of Sunderdhunga Valley, Western Himalaya, with Emphasis on Ethno-Medicinal Plants -- 7. Pinki Gogoi, Pyonim Lungphi, A.P. Das & Ayam Victor Singh * -- Phytomedicines Used In Respiratory Diseases By Traditional Healers Of Lakhimpur & Dhemaji Districts Of Assam, India -- 8. Lydia Yeptho*, T. Ajungla -- Understanding phytomedicinal gastronomic culture of the Nagas in Nagaland, India -- 9. Ritee Basu, Sukanya Dasgupta, Spoorthy N Babu, Ayesha Noor* -- Medicinal Plants in the Indian Traditional Medicine and Current Practices -- 10. Rajeev Ranjan Kumar, Jaidev Chauhan, Vijay Kant Purohit and Pratti Prasad -- Conservation of RET Medicinal and Aromatic plants, for their Appraisal in Traditional Medicines and Current practices in Indian Himalayan Region -- 11. Neva Chaudhary 1* , Suresh K. Ghimire 2 and Ram P. Chaudhary -- Traditional Amchi Medicinal Practice in trans-Himalayas of Nepal: Conservation and Bioprospecting -- 12. Salman Majeed 1* , Muhammad Zafar 1 , Mushtaq Ahmad 1,2 , Shazia Sultana 1 , Muhammad Fethi, Ozdemir 3 , Omer Kilic 4 , Ghulam Yaseen 5 , Nabila 1 -- Appraisal of Medicinal Plants Diversity Inhabited in Deserts Areas -- 13. Karma Yeshi, Phurpa Wangchuk -- Bush Medicinal Plants of the Australian Wet Tropics and Their Biodiscovery Potential -- 14. Kausar Rashid1*, Sufiya Rashid1, Aijaz Hassan Ganie2, Irshad A. Nawchoo1, Mudasir A. Tantry3, Anzar A. Khuroo4 -- Trillium govanianum, a promising endemic medicinal herb of the Himalaya -- 15. K. Abirami, P. Revathi, K. Thenmozhi* and K. Sowndhararajan -- Comprehensive Review on Wild Basil Genus Orthosiphon of Lamiaceae -- 16. T. Soumya, P. R. Jayasree and P. R. Manish Kumar -- Zingiberaceae plants – a cornucopia of promising chemotherapeuticals for cancer cure -- 17. Nikita Patel and Ramar Krishnamurthy -- Moringa oleifera Accessions: Perspectives and application as nutraceuticals and phytomedicines -- 18. Sreeja Puthanpura Sasidharanc, Xuefei Yanga,b, Karuppusamy Arunachalama,b* -- An overview of ethnobotany, phytochemicals and pharmacological properties of Ficus species -- 19. Sunil Kumar 1 , Bikarma Singh 2,3 -- Phytochemistry and pharmacology of Catharanthus roseus (L.) G. Don and Rauvolfia serpentina (L.) Benth. ex Kurz -- 20. Naveen Dhingra* 1 , Shaligram Sharma 2 , Pratima Kumari 3 and Anand Kar 4 -- Resilience Activity of Glycyrrhiza glabra in Relation to Cancer: Chemistry and Mechanism -- 21. Reshmi Chembrammal 1 *, Aswathi Pokkadath 2 and John Ernest Thoppil 3 -- Strobilanthes: A plethora of phytomedicine -- 22. Sonia Mol Joseph* And Amala Dev A.R -- Annonaceae: Tropical medicinal plants with potential anticancer compounds: An overview -- 23. Suman Thamburaj † , Chayanika Sarma † , Anju Mariam Johnson † , Akhila Etikala † and Suresh Kumar Kalakandan* -- Biocolorant from Anisochilus carnosus: A natural food preservative -- 24. Azhagu Saravana Babu. P 1 , Vajiha Aafrin. B 2 , Sagorika Goyali 1 , Geethika. M 1 , Sugumari.V 1 , M. Sukumar -- Therapeutic properties of Nardostachys jatamansi and its applications in Post Chemotherapy induced hair loss in cancer patients -- 25. Marney Pascoli Cereda -- Phototherapeutic potential of cassava (Manihot esculenta, Crantz). -- 26. Saranya Surendran and *Raju Ramasubbu -- Phytochemistry and Pharmacological studies of Indian Cinnamomum Schaeff. -- 27. Silvy Mathew, Reshma Rajan -- Medicinal properties and population studies on Sarcostigma kleinii Wight &Arn. -- 28. Anjana Krishnan1, Jomy Joseph2 and Sudha Kalyanikutty1*, -- The Utility of Natural Mucilage from the Medicinal plant, ‘Patha’ (Cyclea peltata) as an Alternative for Solidifying Agent in Cell Growth Media -- 29. S. N. Preethamol 1 * and John E Thoppil 2 -- Secondary metabolites in Ophiorrhiza brunonis Wight &Arn. (Rubiaceae): A lead towards its anticancer potential -- 30. Kajal Chakraborty -- Marine macroalgae as a treasure house of bioactive compounds and nutraceuticals -- 31. Kapish Kapoor †1* , Priyal Jain †2 Joohee Pradhan †1* -- Plant metabolites as new leads to herbal drug discovery: Approaches and Challenges -- 32. Mudasir Maqbool 1 , Kitika Shenmar 2 , Ansab Akther 3 , Reyaz Hassan Mir 2 , Adil Farooq Wali 4* , Roohi Mohi-ud-din 5* -- Biochanin A Chemistry, Structural Modifications, and Therapeutic Applications: An Update -- 33. Biswajit Patra 1 , Nibedita Das 2 , Mohammad Zaki Shamim 3 , Tapan Kumar Mohanta 4, Bishwambhar Mishra 4 , Yugal Kishore Mohanta 5* -- Dietary Natural Polyphenols Against Bacterial and Fungal Infections: An Emerging Gravity in Health care and Food industry -- 34. Joohee Pradhan 1 * Purnima Paliwal 2† Sunita Panchawat 1† Rohini Trivedi 3† , and Devshree Gayakwad 4† -- Phyto-constituents as Potential Leads for the Development of Novel Antiepileptic Drugs -- 35. Hitesh Chopra 1 , Shabana Bibi 2 , Yugal Kishore Mohanta 3 , Sony Kumari 3 , Atif Amin Baig 4* -- Role of Polyphenols in Cardiovascular diseases -- 36. Alankar Shrivastava -- Steam Distillation: Principle And Applications For The Extraction Of Essential Oils From Plants -- 37. Durga Prasad Barik -- Factors Influencing Agrobacterium-Mediated Transformation Efficiency In Plants – A Case Study -- 38. Dr T V Binu, C B Athira -- Evaluation Of Medicinal Planttager With Reference To Its Substitute -- 39. Shipra Jha1, Shilpi Yadev2 -- Biotechnology: Production of Natural Bioactive Compounds from Leguminous Plants & Disease Management -- 40. Pawan Mulani*, Dr.Sweta S.Koka, Anirudh Padiyar, Dr. R.K. Maheshwari, Dr. G.N. Darwhekar -- Novel Ecofriendly Method Of Extraction For Fixed Oils Using Solvent Action Of Solid Solubilizers -- 41. 1Yasotha Jeyaram, 2Priya Prasannan, 1Arjun Pandian, 2*Ramasubbu Raju -- Conservation attempts of woody medicinal plants of India by Biotechnological tools -- 42. M.V Lakshmi, S. Jeyaraj, and T.S Swapna -- Conservation of endangered medicinal plants by in-vitro propagation methods -- 43. Nadia Iqbal 1* , Sidra Nisar Ahmed 2 , Urooj subhan 1 , Nageen Arif 1 , Humaira Saleem 1 , Farah Deeba 1 -- Application of biotechnology to produce plant-derived biologically important compounds -- 44. Mehmet Zeki Kocak 1 * , Mustafa Güven Kaysim 2 -- Appraisal of Medicinal Plants for Pharmacological Properties -- 45. Yuhong Zheng 1 , Xin Shi 2 , Li Fu 3* -- Pharmacological properties and tissue culture method of endangered medicinal plants -- 46. Morvarid Noormohammadi 1 , Farzad Shidfar 2* -- Natural compounds with pharmacological properties in clinical trials -- 47. Aswathi Pokkadath1, Reshmi Chembrammal2, and John Ernest Thoppil3 -- Phytopharmacological aspects of the genus Terminalia -- 48. Priyanka Soni 1 , Md. Sajid Ghufran 2 and Govinda Rao Duddukuri 3 * -- Anticancer potential of plant-derived compounds: An overview of their epigenetic mode of action -- 49. Nikita Kale -- Treatment of Cancer Using Combination of Herbal & Novel Drug Delivery System -- 50. Nisha Sam Nirmala* 1 , Navina Bala Krishnan 1 , Vaishnavi Vivekanandan 1 , Krishnaraj Thirugnanasambantham -- Anti-Inflammatory Potential Of Lead Compounds And Their Derivatives From Medicinal Plants -- 51. Tanima Bhattacharya a,b# , Debashrita Das c# , Hitesh Chopra d , Atif Amin Baig* e -- Alzheimer disease treatment using natural foods: A perspective overview -- 52. Anjali Saharan 1 , Harkiran Nehra 2 , Chander Parkash 3 , Rakesh Kumar Sindhu 4 , Inderjeet Verma 3 -- Natural products used for the treatment of an autoimmune disorder -- 53. Cristina M. Pérez Zamora 1,2*† , Carola A. Torres 1,2*† and Ana M. Gonzalez 3 -- Strategies to improve antimicrobial activity of natural products: approaches and challenges -- 54. Sinimol Thekkekkoottumughath Peethambaran1* -- Plants Described In Ayurveda With Immunomodulatory Potential -- 55. B Sumithra 1*, Sanjeeb Kumar Mandal 1, B Bishwambhar Mishra 1, Mounika KVSSN 1, Caleb Joel Raj J 1, Aishwarya CVS 1. -- Plant-derived drugs for Alzheimer’s and other neurological disorders -- 56. Afroze Naveed Basha 1 , Ramya Subramanian 2 , Kandeepan Chithan 1 , Gopinath Gurulingam, Vincent 3 , Karthigeyan Murugesan 3 , Ananthavalli Ramachandran 3 , Sivakumar Pethanan 3 , Mani, Panagal 4 , Chella Perumal Palanisamy 5* , Jayakumararaj Ramaraj 6* -- Properties and mechanism of antimicrobial agents from plant derived essential oils -- 57. Thomson Alex 1 , Alankar Shrivastava 2* , Damanpreet Kaur Lang 3 , Rakhi Khabiya 4, Sweta S. Koka 4 , Yasmin Sultana 1* -- Nanotechnological Modus Operandi For The Delivery Of Cytotoxic Phytochemicals -- 58. a Arun John and b Rinu Elizabeth Roy -- Plant Based Green Nano Particles In Cancer Diagnosis And Chemotherapy -- 59. Jeyanthi Palanivelu, R. Sai Nandhini, Kalpana Shree S, Phalguni Maity, G.S.Madhumathi, Anindita Bhar , Jeyanthi Palanivelu* -- Use Of Nanoparticles In Cancer Therapy Using Plant Resources -- 60. Md. Sajid Ghufran 1* , Priyanka Soni 2 and Govinda Rao Duddukuri 3 -- The global concern for cancer emergence and its prevention: A systematic unveiling of the present scenario -- 61. Shaikh Ajij Ahmed Makbul 1,* Sayeedur Rahman 2 -- Regularly used poisonous medicinal pl.
    Abstract: This book focuses on natural products, in particular medicinal plants and their derived products, as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery . There are several advantages for plant-derived therapeutics, including wide availability, diverse pharmacological actions, and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying the efficacy and safety of medicinal plants and phytochemicals in treating human diseases. A plethora of basic studies has also unraveled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products, and drug interactions remain to be systematically documented. Bioprospecting of Tropical Medicinal Plants represents a comprehensive analysis of natural products, mainly medicinal plants and phytochemicals. It includes detailed medicinal properties and pharmacological action from in vitro models to clinical trials. The goal is to present the readers a carefully curated collection of plant-derived natural products and their underlying molecular mechanisms.
    Type of Medium: Online Resource
    Pages: XVII, 1544 p. 150 illus., 132 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287800
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Origin of watermelon -- Whole genome sequencing of watermelon and other relevant genomic resources -- Watermelon Genetic Resources and Diversity -- Watermelon genomic resources for disease resistance -- - The NLR family of disease resistance genes in cultivated watermelon and other cucurbits: opportunities and challenges -- Mapping of economic and quality related loci in watermelon -- Genetics and genomics of fruit and quality traits of watermelon -- Genetics and genomics of host resistance and develop disease tolerant cultivars of watermelon -- Molecular and Metabolic Regulation of Nutraceuticals in Watermelon -- Challenges of Traditional breeding in watermelon.
    Abstract: This book is the first comprehensive compilation of deliberations on botany, genetic resources and diversity, classical genetics and traditional breeding, genetic transformation, and detailed enumeration on molecular maps and mapping of economic genes and QTLs, whole genome sequencing and comparative genomics in watermelon, and elucidation on functional genomics. The genomic resources for disease resistance, genomics of fruit and quality traits of watermelon, and molecular and metabolic regulation of nutraceuticals in watermelon are discussed. Mapping of quality traits, and biotic and abiotic resistance is also to be discussed. The genome draft of watermelon and application of genome editing are covered. The book contains approximately 250 pages and over 10 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in academia and relevant private companies interested in horticulture, genetics, breeding, pathology, entomology, physiology, molecular genetics and genomics, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful for seed industries. .
    Type of Medium: Online Resource
    Pages: V, 172 p. 33 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031347160
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Biologicals. ; Biopharmaceutics. ; Pharmacology. ; Preclinical Research. ; Biologics.
    Description / Table of Contents: Chapter 1_Introduction -- Chapter2_Systematic literature review (SLR) -- Chapter 3_Registration and software’s -- Chapter 4_Quality Assessment of Studies -- Chapter 5_Extraction and Analysis of data -- Chapter 6_Models in Meta-analysis -- Chapter 7_Heterogeneity and Publications bias -- Chapter 8_Sensitivity and subgroup analysis -- Chapter 9_Meta-regression -- Chapter 10_Plots in Meta-analysis -- Chapter 11_Network Meta-analysis -- Chapter 12_Common mistakes -- Chapter 13_Challenges -- Chapter 14_Future Perspectives -- Chapter 15_Future perspectives.
    Abstract: This book provides conceptual information on the various processes involved in meta-analysis. It examines the importance of meta-analysis for the analyses of clinical data to draw a valid conclusion using suitable software. The initial sections of the book introduce meta-analysis, how to perform a systematic literature review (SLR), quality assessment of studies, extraction, and analysis of data. The subsequent section of the book contains information on advanced topics including, meta-regression, network meta-analysis, issues, mistakes, and future perspectives. In summary, the book provides a statistical method for combining the results of different studies on the same topic and resolving conflicts among studies. This book is written with the intent to allow a wide range of readers including students, researchers, and health care professionals, including physicians, nurses, pharmacists, and paramedical, and is also helpful for a beginner who would like to do a meta-analysis.
    Type of Medium: Online Resource
    Pages: XXII, 119 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923700
    DDC: 615
    Language: English
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  • 36
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Medical genetics. ; Clinical health psychology. ; Human physiology. ; Pharmacology. ; Neuroscience. ; Psychiatry. ; Medical Genetics. ; Health Psychology. ; Human Physiology.
    Description / Table of Contents: Introduction -- Development, anatomy and histology of the mesentery -- The mesenteric intersitium -- Mesnteric organ lymphatics -- The mesentery as an immunological organ -- Bacterial translocation to the mesentery -- The microbiome of mesenteric lymh nodes -- Mesenteric Adenopathy and adenitis -- The effects of mesenteric inflammation on the intestine -- The mesentery as an ADME organ -- Targteing the mesentery using surgery -- Future directions.
    Abstract: The volume summarizes the most recent advances in our understanding of the mesentery and explains the how these are important in inflammation. It comprises a series of state of the art chapters by leading authorities in each area. It explains how recent advances in our understanding of the mesenteric organ, have advanced the diagnosis and treatment abdominal and systemic conditions including cancer, inflammatory bowel disease and endocrine conditions such as diabetes, and circulatory disorders such as atherosclerosis. .
    Type of Medium: Online Resource
    Pages: X, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031177743
    Series Statement: Progress in Inflammation Research, 90
    DDC: 615
    Language: English
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  • 37
    Keywords: Botany. ; Agriculture. ; Genetics. ; Biotechnology. ; Plant Science. ; Agriculture. ; Genetics and Genomics. ; Biotechnology.
    Description / Table of Contents: Chapter 1: Breeding Field Crops – History, Current Status And Introspections -- Chapter 2: Wheat Breeding -- Chapter 3: Rice Breeding -- Chapter 4: Maize Breeding -- Chapter 5: Barley Breeding -- Chapter 6: Pearl Millet Breeding. Chapter 7: Sorghum Breeding. Chapter 8: Small Millets Breeding -- Chapter 9: Sugarcane Breeding -- Chapter 10: Jute Breeding -- Chapter 11: Cotton Breeding -- Chapter 12: Maintenance Breeding Of Pusa Basmati Varieties -- Chapter 13: Maintenance Breeding -- Chapter 14: Efficient Breeding Of Crop Plants -- Chapter 15: Brassica Breeding -- Chapter 16: Groundnut Breeding -- Chapter 17: Soybean Breeding -- Chapter 18: Castor Breeding -- Chapter 19: Sunflower Breeding -- Chapter 20: Chickpea Breeding -- Chapter 21: Pigeonpea Breeding -- Chapter 22: Mungbean Breeding -- Chapter 23: Urdbean Breeding -- Chapter 24: Lentil Breeding -- Chapter 25: Fieldpea Breeding -- Chapter 26: Lathyrus Breeding.
    Abstract: This book is an advanced textbook and a reference book for the post-graduate plant-breeding students and the plant breeders. It consolidates fundamental concepts and also the latest advances in plant-breeding practices including development in crop genomics. It contains crop wise explanation on origin, reproduction, genetics of yield contributing traits, biotic and abiotic stresses, nutritional improvement and crop specific plant-breeding procedures and techniques. The chapters are planned to describe crop-focused breeding procedure for the major crop plants as per their economic importance. The recent developments in breeding of field crops have been reported. The recent progress made in mapping traits of economic importance has been critically reviewed for each crop. The progress made in markers assisted selected in few crops has been summarized. This book bridges the knowledge gap and bring to the researchers and students information on modern breeding tools for developing biotic and abiotic stress tolerant, climate resilient and micronutrient rich varieties of field crops. The chapters in book are contributed by experienced Plant Breeders.
    Type of Medium: Online Resource
    Pages: XIV, 1389 p. 109 illus., 98 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692574
    DDC: 580
    Language: English
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  • 38
    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    DDC: 615
    Language: English
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  • 39
    Keywords: Botany. ; Biology Technique. ; Biotechnology. ; Plant Science. ; Biological Techniques. ; Biotechnology.
    Description / Table of Contents: Chapter 1 Science and philosophy -- Chapter 2 Student’s proposal, dissertation, or thesis -- Chapter 3 Research integrity and publication ethics -- Chapter 4 Good Research Practices -- Chapter 5 Publication 101 -- Chapter 7 Lessons learned from Nature’s reports -- Chapter 8 Success can be learned.
    Abstract: This monograph offers a comprehensive guide to good research practices and mindsets, covering a wide range of topics across 8 chapters. Readers will find numerous themes and strategies that can help them develop their research skills and achieve their objectives, from effective proposal writing to stress management and upskilling. This book explains the purpose, process, tips, and mistakes of writing proposals, theses, articles, and reviews in clear and straightforward language, allowing readers to develop good research plans. By applying the advice and insights offered in this book, students and researchers can improve the quality of their work, cultivate research integrity, and develop good publication plans, write well, and reduce rejection rates. Research outputs will be more likely to be of high quality if students and researchers are encouraged to cultivate these pieces of advice. The focus of the book is not solely on the outcomes of research. Rather, it also delves into mindset, habits, adaptability, time management, stress management, recent tools for upskilling, planning, and execution. Throughout the book, the author seeks to instill a growth mindset in the readers, encouraging them to develop positive research habits and behaviors. KPIs, particularly publications, shall not be used as a reason to erode research integrity and ethnicity; therefore, plagiarism, self-citation, falsifying data, exaggerating findings, authorship in publications, the use of AI tools, CRediT, and COPE are discussed. This book contains interviews with high-profile researchers, top management at institutions, policy advisers, etc., whose opinions and advice the readers will find valuable. Overall, this all-in-one guide is an essential resource for postgraduate students, post-doctoral fellows, and academics who are struggling to find a survival strategy in the rapidly changing research environment. The book assists readers in developing right mindset, planning their research and publications, and in achieving their predetermined objectives. .
    Type of Medium: Online Resource
    Pages: XXIII, 241 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819928125
    DDC: 580
    Language: English
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  • 40
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Keywords: Botany. ; Microbiology. ; Biodiversity. ; Applied ecology. ; Plants Evolution. ; Plant ecology. ; Plant Science. ; Microbiology. ; Biodiversity. ; Applied Ecology. ; Plant Evolution. ; Plant Ecology.
    Description / Table of Contents: Introduction: Façades colonized by aerophytic microorganisms -- Façades as a functional part of a building -- The environment façade -- History of aerobiology, in respect of research on man-made surfaces -- Tools/Methods -- Experimental investigations and the assessment of primary growth of microorganisms on modern buiding structures -- Assessment of starter germ load of materials. Germ counts for specimens -- Culture based taxonomic analysis -- Taxonomy -- Pre-culture investigation -- Sample collection and preparation -- Establishment of pure cultures -- Background concentrations -- Air germ measurement -- Sedimentation -- Germ load of precipitation -- Ecophysiologic data -- Testing methods in respect of ths susceptibility of building products against colonisation by microorganisms -- Aerophytic organisms colonizing façades: their diversity and taxonomy with recognition of ecophysiological characteristics -- Regnum Eubacteria – non oxygen phosynthetic active groups -- Regnum Archaea -- Division Rhodophyta – Class Rhodophyceae -- Division Stramenopiles (Heterokonta), Class Bacillariophyceae -- Division Stramenopiles (Heterokonta), Class Xanthophyceae -- Division Stramenopiles (Heterokonta), Class Eustigmatophyceae -- Division (Infraregnum) Chlorophyta, Class Chlorophyceae -- Division (Infraregnum) Streptophyta -- Class Bryopsida – Musci -- Class Pteridopsida -- Subregnum Eumycota -- Division Archemycota -- Class Zygomycetes -- Division Ascomycota -- Class Ascomycetes -- Division Basidiomycota -- Class Basidiomycetes -- Form of organisation Lichenes -- Formgroup Ascolichenes -- Synopsis -- Summary -- Acknowledgements -- Glossary 1 -- Glossary 2 (important technical terms) -- Literature.
    Abstract: This book provides a detailed overview of the microorganisms that form the initial growth on the exterior façades of buildings. It deals with the ecophysiological properties that characterize the basic conditions under which these microorganisms can occur on façades. In addition to an identification key for the types and forms of microorganisms, this book provides a detailed description of the individual organisms, stating their ecological range. Furthermore, the various ecological parameters are discussed in short chapters. Measures to prevent and combat the colonization of façades with microorganisms are also addressed. Specialists (architects, construction experts), builders, scientists and master students can find all the information they need on facade algae and fungi here. The authors Dr. Wolfgang Karl Hofbauer is chief scientist (taxonomy, ecophysiology and genetics) of the department Environment, Sensors and Hygiene at the Fraunhofer Institute for Building Physics. His professional research areas are taxonomy and ecophysiology of organisms on building surfaces, about which he did his doctorate in 2008, genetic barcoding of building relevant (micro)organisms and greening of building surfaces. Retired Prof. Dr. Dr.h.c Georg Gärtner worked and researched at the University of Innsbruck on the cultivation and taxonomy of soil-and airborne. algae for many years. In 2012, Prof. Gärtner was awarded an honorary doctorate by Sofia University for his services to the cooperation in algal studies between the botanical institutes of the University of Innsbruck and the University of Sofia.
    Type of Medium: Online Resource
    Pages: XI, 323 p. 185 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783662548332
    DDC: 580
    Language: English
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    Keywords: Pharmacology. ; Human physiology. ; Nanotechnology. ; Biology Technique. ; Pharmacology. ; Human Physiology. ; Nanotechnology. ; Experimental Organisms.
    Description / Table of Contents: Chapter 1. Nanotechnology : Application in biology and medicine -- Chapter 2. Biological activities of nanoparticles and mechanism of action -- Chapter 3. Application of nanoparticles in Drug delivery -- Chapter 4. Antimicrobial activity of metallic nanoparticles using prokaryotic model organisms -- Chapter 5. Modelling nanoparticles parameters for antibacterial activities -- Chapter 6. Saccharomyces cerevisiae as model organism to study biological activities of nanoparticles -- Chapter 7. Investigation of Biological activities of Nanoparticles using Cell Lines -- Chapter 8. Caenorhabditis elegans: a model organism to decipher biological activities of nanoparticles -- Chapter 9. Zebra fish model system to investigate biological activities of nanoparticles -- Chapter 10. Drosophila melanogaster - A model organism to understand biological activities of nanoparticles -- Chapter 11. Understanding the biological activities of nanoparticles using murine models -- Chapter 12. Insecticidal activity nanoparticles and mechanism of action -- Chapter 13. Routes of Exposures and Toxicity of Nanoparticles -- Chapter 14. Toxicological evaluation of nanoparticles using prokaryotic model organisms -- Chapter 15. Evaluation of Toxicity Nanoparticles using Cell lines -- Chapter 16. Saccharomyces cerevisiae : Model organism to evaluate nanoparticles toxicity -- Chapter 17. Caenorhabditis elegans: Evaluation of nanoparticle toxicity -- Chapter 18. Zebra fish: A laboratory model to evaluate Nanoparticle Toxicity -- Chapter 19. Evaluation of toxicity of nanoparticles using Brine Shrimp -- Chapter 20. Drosophila Model to Decipher the Toxicity of Nanoparticles -- Chapter 21. Murine models to understand the toxicity of nanoparticles -- Chapter 22. Challenges and future perspectives of Nanotoxicology.
    Abstract: This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.
    Type of Medium: Online Resource
    Pages: XIII, 466 p. 64 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811517020
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Plants Evolution. ; Plants Development. ; Plant Science. ; Plant Evolution. ; Plant Development.
    Description / Table of Contents: Chapter 1. The two contrary theories about organogenesis in morphology of the higher plants.-chapter 2. Saunders’ Leaf-skin Theory of Stem -- Chapter 3. Leaves are split axes -- Chapter 4. Re-evaluation of the evidences for the Telome Theory -- Chapter 5. What do hooded-awn barley, bitter bamboo, tortoise shell bamboo, paspalum and crabgrass show us? -- Chapter 6. The ontogenesis of higher plants -- Chapter 7. The organogenesis of higher plants -- Chapter 8. Conclusion.
    Abstract: This book written by Professor Chi Yen of Sichuan Agricultural University in Chinese was published by China Agriculture Press (ISBN 978-7-109-22791-0). It describes a new theory on the constitution of organs of the higher plants based on experimental evidence, the multiple secondary axis theory. This theory states that all organs of the higher plants are the constitution of multiple secondary axes. The primary axis extends bipolarly to initiate the above- and the below-ground parts of a plant, from which secondary axes develop. Leaves are split, expanded upper ends of terminal secondary axes. Stems are merged lower ends of the secondary axes, Vascular bundles are secondary structures developed within the axes which interconnect with each other to form the central core of the stem and branches and the veins in the leaves. Roots form through the downward extension of the lower ends of the axes toward or within the underground and branch roots are unsplit secondary axes. All new axes emerge from the inner side of existing, split axes. All floral organs including fruits, seeds and vegetative reproduction organs such as bulbils and plantlets, are deformed axes. This theory is significant in guiding the scientific design of the ideotype of crops to optimize the development of the economically important organ(s) of a crop.
    Type of Medium: Online Resource
    Pages: XII, 160 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811916854
    DDC: 580
    Language: English
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    Keywords: Pharmacology. ; Invertebrates. ; Medicine Research. ; Biology Research. ; Epidemiology. ; Biochemistry. ; Pharmacology. ; Invertebrate Zoology. ; Biomedical Research. ; Epidemiology. ; Biochemistry.
    Description / Table of Contents: Chapter 1. Introduction: The snakebite problem -- Chapter 2. Evolution of snakes and systematics of Big Four venomous snakes of India -- Chapter 3. Snake venom: Composition, evolution, function, and biomedical applications -- Chapter 4. Indian spectacled cobra (Naja naja) -- Chapter 5. Indian common Krait (Bungarus cerelus) -- Chapter 6. Indian Russell’s viper (Daboia russelii) -- Chapter 7. Indian Saw-scaled viper (Echis carinatus) -- Chapter 8. Prevention and Treatment of Big Four Snakebite in India.
    Abstract: This book provides detailed and updated knowledge about medically important ‘Big Four’ venomous snakes of India (Indian spectacled cobra, Indian common krait, Indian Russell’s viper, and Indian saw-scaled viper). This book essentially covers the snakebite problem in the world with particular reference to Asia and India. It discusses the evolution and systematics of venomous snakes, emphasizing ‘Big Four’ venomous snakes of India; the evolution and composition of venoms determined by traditional biochemical and modern proteomic analyses. It also describes the pharmacological properties of enzymatic and non-enzymatic toxins of ‘Big Four’ venomous snakes of India. Different chapters discuss exciting topics such as species-specific and geographical differences in venom composition and its impact on pathophysiology and clinical manifestations of snakebite envenomation in India, biomedical application of Indian snake venom toxins; production and quality assessment of commercial antivenom, prevention, and treatment of snakebite in India, adverse effects of antivenom including strategies to combat antivenom reactions inpatient. This book caters to toxinologists, pharmacologists, zoologists, antivenom manufacturers, biochemists, clinicians, evolutionary biologists, herpetologists, and informed non-specialists interested to know about the Indian snake venoms. .
    Type of Medium: Online Resource
    Pages: XI, 161 p. 55 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811628962
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Description / Table of Contents: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Abstract: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Type of Medium: Online Resource
    Pages: XII, 111 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287602
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Abstract: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Type of Medium: Online Resource
    Pages: XVII, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811975509
    DDC: 615
    Language: English
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    Keywords: Botany. ; Food Safety measures. ; Plant diseases. ; Agriculture. ; Environment. ; Public health. ; Plant Science. ; Food Safety. ; Plant Pathology. ; Agriculture. ; Environmental Sciences. ; Public Health.
    Description / Table of Contents: Introduction -- Ancient Spores -- Spores of My Life -- Scary Spores -- Spores of the Future -- Conclusions.
    Abstract: This book aims to describe, though in a quite light way, the social role of plant diseases, letting the reader know the topical importance of plant pathology, as well as the role of plant pathologists in our society. Plant diseases caused, in the past, significant economic losses, deaths, famine, wars, and migration. Some of them marked the history of entire countries. One example among many: the potato late blight in Ireland in 1845. Today plant diseases are still the cause of deaths, often silent, in developing countries, and relevant economic losses in the industrialized ones. This book, written with much passion, neither wants to be a plant pathology text. On the contrary, it wants to describe, in simple words, often enriched by the author's personal experience, various plant diseases that, in different times and countries, did cause severe losses and damages. Besides the so-called “historical plant diseases”, in the process of writing this book, she wanted to describe also some diseases that, though not causing famine or billions of losses, because of their peculiarity, might be of interest for the readers. Thus, this book has not been conceived and written for experts, but for a broader audience, of different ages, willing to learn more about plant health and to understand the reasons why so many people in the past and nowadays choose to be plant pathologists. This is because plants produce most of the food that we consume, that we expect healthy and safe, and because plants make the world beautiful. The title “Spores” is evocative of the reproduction mean of fungi. Spores are small, light structures, often moving fast. The chapters of this book are short and concise. Just like spores!
    Type of Medium: Online Resource
    Pages: XXVI, 289 p. 174 illus., 166 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030699956
    DDC: 580
    Language: English
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    Keywords: Botany. ; Food science. ; Cancer Prevention. ; Nutrition   . ; Plant Science. ; Food Science. ; Cancer Prevention. ; Nutrition.
    Description / Table of Contents: 1. Etiology of obesity, cancer, and diabetes -- 2. Pathophysiology of Obesity and Diabetes -- 3. Pathophysiology of obesity and cancer: Drugs and signaling targets -- 4. Peptides Involved in body weight regulation -- 5. Insulin resistance- a link between obesity and cancer -- 6. Role of the cytoskeletal protein, actin in various diseases -- 7. Diabetes mellitus and its management with plant-based therapy -- 8. Fruits and vegetables as sources of functional phytochemicals for the management of obesity, diabetes, and cancer -- 9. Spices in diabetes, cancer and obesity treatment -- 10. MicroRNAs as Targets of Dietary Phytochemicals in Obesity and Cancer -- 11. Natural phenolic compounds as anti-obesityand anti-cardiovascular disease agent -- 12. Harnessing the Potential of Phytochemicals for Breast Cancer Treatment.
    Abstract: This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as anti-diabetic, anti-cancer and anti-obesity agents and describe their mechanisms to regulate cell metabolism. Written by global team of experts, Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes describes the potentials of novel phytochemicals, their sources, and underlying mechanism of action. The chapters were drawn systematically and incorporated sequentially to facilitate proper understanding. This book is intended for nutritionists, physicians, medicinal chemists, drug developers in research and development, postgraduate students and scientists in area of nutrition and life sciences.
    Type of Medium: Online Resource
    Pages: VIII, 265 p. 22 illus., 18 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030729998
    DDC: 580
    Language: English
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    Keywords: Botany. ; Genetics. ; Biology Technique. ; Biology. ; Molecular biology. ; Biochemistry. ; Plant Science. ; Genetics and Genomics. ; Biological Techniques. ; Biological Sciences. ; Molecular Biology. ; Chemical Biology.
    Description / Table of Contents: 1.Phytochemical genomics: integration of omics approaches for understanding genomic basis of phytochemicals -- 2.Gene-metabolite networks -- 3.Computational approaches in phytochemical genomics -- 4.Databases relevant to phytochemicals and genes responsible -- 5.Biosynthetic pathways of important metabolites using genomics and metabolomics approaches -- 6.Phytochemical diversity and the diverse roles of phytochemicals in plants -- 7.Role of genomics and metabolomics for breeding crops with higher quantity of metabolites -- 8.Metabolic quantitative trait loci mapping of medicinal plants and crops -- 9.Tools for metabolomics analysis of plants -- 10.Trichomes as an important chemical factories of metabolites -- 11.Stress and metabolites -- 12.Evolution of metabolite diversity and defense mechanisms in plants -- 13.Pathway engineering of genes -- 14.Demand-supply of phytochemicals and the need for ensuring sustainable supply of plants -- 15.Drug discovery and omics -- 16.Gene editing technologies for scaling up production of secondary metabolites -- 17.Medicinal plants and use of omics approaches -- 18.Metabolomics of important medicinal plants -- 19.Transcriptomics of important medicinal plants.
    Abstract: This book provides a comprehensive reference for various plant bioactive compounds for research and pharmacological significance across the entire spectrum of phytochemical genomics. The book opens with general information on diversity, analysis and genomic basis of phytochemicals, computational approaches, databases for responsible genes, and biosynthetic pathways, and it delves very much into the details behind phytochemical diversity and diverse roles of plant metabolites. The later parts of the book also explore the direct drug discovery and omics approaches including metabolomics, transcriptomics, as well as gene editing technology experiments to further inspire readers into its unlimited potentials. Each chapter includes detailed analysis and relevant experiments for better and deeper understanding of the concepts. The book will be an invaluable aid for medicinal plant researchers and a rich source of information and advice for advanced undergraduates and graduates in the fields of medicine, nutraceuticals, cosmetics, flavor, and fragrance studies.
    Type of Medium: Online Resource
    Pages: XVIII, 698 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811957796
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Metabolism Disorders. ; Pharmacology. ; Metabolic Disease.
    Description / Table of Contents: Part I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
    Abstract: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
    Type of Medium: Online Resource
    Pages: VIII, 513 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030999957
    Series Statement: Handbook of Experimental Pharmacology, 274
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Biology Technique. ; Cytology. ; Imaging systems in biology. ; Plant Science. ; Biological Techniques. ; Cell Biology. ; Biological Imaging.
    Description / Table of Contents: Chapter 1 - Introduction to Plant Histopathology -- Chapter 2 - Sample Preparation for light and Electron microscopy -- Chapter 3 - Plant Histopathology techniques -- Chapter 4 - Fungal detection Chapter 5 - Bacteria detection -- Chapter 6 - Virus detection.
    Abstract: This handbook presents a compilation of plant histopathology laboratory practices and microscopy techniques for study plant tissues under biotic stress. It will serve as an easy-to-reference material for professors, undergraduate and graduate students and researchers from different areas who work with the interaction between plants and pathogens, whether they are fungi, viruses or bacteria. Besides, it will also help unveil the structural, ultrastructural and histochemical changes induced by plants when challenged by plant pathogens.
    Type of Medium: Online Resource
    Pages: XI, 80 p. 22 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031146596
    DDC: 580
    Language: English
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    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Medical genetics. ; Pharmacology. ; Biomedical Research. ; Medical Genetics.
    Description / Table of Contents: Chapter 1. Introduction and Principles of Pharmacogenomics and Precision medicine -- Chapter 2. Pharmacogenomics in Cardiovascular Diseases -- Chapter 3. Pharmacogenomics of Antitumor Chemotherapeutic Agents -- Chapter 4. Pharmacogenomics of Antitumor Targeted Agent and Immunotherapy -- Chapter 5. Pharmacogenomics of Immunosuppressant -- Chapter 6. Pharmacogenomics of Psychiatric drugs -- Chapter 7. Pharmacogenomics of Anti-Infective Agents -- Chapter 8. Pharmacogenomics of Antithrombotic drugs -- Chapter 9. Pharmacogenomics in Therapeutic Drug Monitoring -- Chapter 10. Pharmacomicrobiomics -- Chapter 11. Genotyping technology in Pharmacogenomics -- Chapter 12. The Ethical, Legal and Regulatory Issues Associated with Pharmacogenomics -- Chapter 13. Cost-effectiveness of pharmacogenetic-guided treatment -- Chapter 14. Application of pharmacogenomics in drug discovery and development -- Chapter 15. Barriers and Solutions in Clinical Implementation of Pharmacogenomics for Personalized Precision Medicine.
    Abstract: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
    Type of Medium: Online Resource
    Pages: VIII, 289 p. 33 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811538957
    DDC: 615
    Language: English
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  • 55
    Keywords: Botany. ; Energy policy. ; Energy and state. ; Pharmacology. ; Pharmacy. ; Ethnology Latin America. ; Culture. ; Plant Science. ; Energy Policy, Economics and Management. ; Pharmacology. ; Pharmacy. ; Latin American Culture.
    Description / Table of Contents: Chapter 1. Herbal Medicines in Argentina, Chile and Uruguay -- Chapter 2. The Native Floras of Argentina, Chile and Uruguay as Sources of Aromatic Products -- Chapter 3. Acantholippia seriphioides -- Chapter 4. Adesmia boronioides -- Chapter 5. Aloysia gratissima -- Chapter 6. Aloysia polystachya -- Chapter 7. Aristotelia chilensis -- Chapter 8. Artemisia copa -- Chapter 9. Aspidosperma quebracho blanco -- Chapter 10. Baccharis dracunculifolia -- Chapter 11. Baccharis tola and B. boliviensis -- Chapter 12. Berberidaceae from Chile -- Chapter 13. Bulnesia sarmientoi -- Chapter 14. Calceolaria spp -- Chapter 15. Dysphania ambrosioides -- Chapter 16. Chiliotrichum diffusum -- Chapter 17. Cissampelos spp -- Chapter 18. Colliguaja integérrima -- Chapter 19. Crinodermum spp -- Chapter 20. Cyclolepis genistoides -- Chapter 21. Eugenia uniflora -- Chapter 22. Fabiana imbricata -- Chapter 23. Fabiana spp -- Chapter 24. Gentianella spp -- Chapter 25. Gleditsia amorphoides -- Chapter 26. Hydrocotyle bonariensis -- Chapter 27. Ibicella lutea -- Chapter 28. Ilex paraguariensis -- Chapter 29. Ligaria cuneifolia -- Chapter 30. Lippia turbinata and L. fissicalyx -- Chapter 31. Lithraea molleoides -- Chapter 32. Madia sativa -- Chapter 33. Minthostachys mollis -- Chapter 34. Mulinum spinosum -- Chapter 35. Nectandra spp -- Chapter 36. Nothofagus antárctica -- Chapter 37. Parastrephia spp -- Chapter 38. Passiflora spp -- Chapter 39. Peumus boldus -- Chapter 40. Picrasma crenata -- Chapter 41. Quillaja brasiliensis -- Chapter 42. Quillaja saponaria -- Chapter 43. Schinus molle & S. areira -- Chapter 44. Solanum crispum -- Chapter 45. Solanum sisymbrifolium -- Chapter 46. Tagetes minuta -- Chapter 47. Zuccagnia punctata.
    Abstract: This volume, as the seventh of the series Medicinal and Aromatic Plants of the World, deals with the medicinal and aromatic plant (MAPs) treasures of the so-called Southern Cone, the three southernmost countries (Argentina, Chile and Uruguay) of South America. Similarly to the previous volumes of the series, the main focus is to collect and provide information on major aspects of botany, traditional usage, chemistry, production / collection practices, trade and utilization of this specific group of plants. The contributors, who are recognized professionals and specialist of the domain, have collected and present state of the art information on 41 species. Most of these are not only of interest from the scientific point of view, but hold also a potential for the prospective utilization of the decreasing, occasionally overexploited / endangered medicinal plant resources of this huge continent. The book is expected to serve as a source of information also on some less known or less studied species. As such the volume is expected to support future research and public health professionals.
    Type of Medium: Online Resource
    Pages: X, 551 p. 109 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030628185
    Series Statement: Medicinal and Aromatic Plants of the World, 7
    DDC: 580
    Language: English
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    Keywords: Pharmacology. ; Human physiology. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Human Physiology. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: The effect of curcumin supplementation on pulse wave velocity in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled trial -- Role of Curcumin in Regulating Long Noncoding RNA Expression in Cancer -- The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-blind, Randomized, Placebo-Controlled Trial -- Protective effects of curcumin phytosomes against high-fat diet-induced atherosclerosis -- Intravenous Curcumin Mitigates Atherosclerosis Progression in Cholesterol-fed Rabbits -- Updated review on the role of curcumin in gastrointestinal cancers -- Curcumin can bind and interact with CRP: an in silico study -- Antifungal activities of curcumin and difluorinated curcumin against clinical dermatophyte isolates -- Therapeutic Effect of Curcumin in Women with Polycystic Ovary Syndrome Receiving Metformin: A Randomized Controlled Trial -- Effect of Curcumin on Severity of Functional Dyspepsia; a Triple Blinded Clinical Trial -- Possible mechanisms and special clinical considerations of curcumin supplementation in patients with COVID-19 -- Paving the road toward exploiting the therapeutic effects of ginsenosides: an emphasis on autophagy and endoplasmic reticulum stress -- Medicinal plants and phytochemicals regulating insulin resistance and glucose homeostasis in type 2 diabetic patients: A clinical review -- Plants with anti-addictive potential -- Use of Plant-Derived Natural Products in Sleep Disturbances -- The effects of nutraceuticals and herbal medicine on Candida albicans in oral candidiasis: a comprehensive review -- Pharmacological properties of the plant-derived natural products cannabinoids and implications for cardiovascular health -- Beneficial effects of plant-derived natural products on non-alcoholic fatty liver disease -- Crocin Improves Oxidative Stress in Testicular Tissues of Streptozotocin-Induced Diabetic Rats -- Beneficial Medicinal Plants for Memory and Cognitive Functions Based on Traditional Persian Medicine -- The use of medicinal plants for the treatment of alopecia in the Canon of Avicenna: an evidence-based review -- Ethnobotanical uses, phytochemistry and pharmacology of different Rheum species (Polygonaceae): A review -- Genus Rosa: A review of ethnobotany, phytochemistry and traditional aspects according to Islamic traditional medicine (ITM) -- Ethnobotany, Phytochemistry, traditional and modern uses of Actaea racemosa L. (Black cohosh): A review -- Ethnobotany, phytochemistry and pharmacological features of Centella asiatica: a comprehensive review -- Ethnomedicinal uses, phytochemistry and pharmacology of different Cichorium species (Asteraceae): A review -- Medicinal species of the genus Berberis: A review of their traditional and ethnomedicinal uses, phytochemistry and pharmacology -- Protective effects of intravenous magnesium sulfate in stroke patients receiving amiodarone: A randomized controlled trial -- In silico identification of novel interactions for FABP5 (Fatty Acid-Binding Protein 5) with nutraceuticals: Possible repurposing approach.
    Abstract: Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal of this contributed volume is to present a comprehensive collection on most important therapeutic aspects of plant-derived natural products and their molecular mechanisms of action.
    Type of Medium: Online Resource
    Pages: X, 603 p. 814 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030648725
    Series Statement: Advances in Experimental Medicine and Biology, 1308
    DDC: 615
    Language: English
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    Keywords: Botany. ; Plant ecology. ; Plants Reproduction. ; Plants Evolution. ; Conservation biology. ; Ecology . ; Plant Science. ; Plant Ecology. ; Plant Reproduction. ; Plant Evolution. ; Conservation Biology.
    Description / Table of Contents: 1. Melastomataceae diversity and distribution -- 2. History of Classification of the Melastomataceae -- 3. General morphology and terminology -- 4. Historical biogeography of Melastomataceae -- 5. An overview of Melastomataceae classification and phylogenetics -- 6. Revisiting character evolution in the Myrtales and its bearing on classification: Should the circumscription of Melastomataceae include the “memecyloids”? -- 7. Systematics of Kibessieae -- 8. Systematics of Astronieae -- 9. Phylogeny and systematics of Henrietteeae -- 10. The tribe Miconieae: many genera or one genus? -- 11. Systematics and taxonomy of the Merianieae -- 12. Systematics of Bertolonieae and Trioleneae -- 13. Systematics of Blakeeae -- 14. The tribe Cyphostyleae; exceptions that prove the rules -- 15. Systematics of Sonerileae and Dissocheteae: creating order out of chaos -- 16. Systematics of Cambessedesieae -- 17. Systematics of Rhexieae -- 18. Systematics of Microlicieae -- 19. Systematic studies in the Neotropical tribe Marcetieae -- 20. Melastomateae: a review on the taxonomic history- morphology- molecular phylogeny and biogeography -- 21. Comparative floral ontogeny of Melastomataceae -- 22. Seed morphological features in Melastomataceae -- 23. Patterns of Chromosome Number Diversity and Evolution in the Melastomataceae -- 24. Apomixis in Melastomataceae: Diversity of developmental mechanisms and ecological consequences -- 25. Pollination syndromes and flower diversification in Melastomataceae -- 26. Stamen diversity in Melastomataceae: morphology- color and function -- 27. Patterns of diversification of Miconia (Miconieae) in the Greater and Lesser Antilles -- 28. Colonization by Melastomataceae and its diversification in the Atlantic Forest -- 29. A review of the paleobotanical record of Melastomataceae -- 30. Shapes of species responses to soil fertility in lowland Amazonian Melastomataceae -- 31. Seed germination ecology in Neotropical Melastomataceae -- 32. Seed dispersal ecology in Neotropical Melastomataceae -- 33. Myrmecophytism in the Melastomataceae -- 34. How non-native invasive Melastomataceae inform a greater understanding of the biology and genetics of the family -- Conclusions.
    Abstract: This book presents a synthesis of critical new information for the Melastomataceae, one of the ten richest families among flowering plants with over 5,800 species that has its diversity highly concentrated in the tropics tropical or subtropical areas. It describes the family’s global diversity and distribution and summarizes recent advances in systematics, evolution, biogeography, reproductive biology and ecology.
    Type of Medium: Online Resource
    Pages: XXIV, 793 p. 83 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030997427
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Therapeutics. ; Pharmaceutical chemistry. ; Biomaterials. ; Pharmacology. ; Translational Research. ; Therapeutics. ; Pharmaceutics. ; Biomaterials.
    Description / Table of Contents: Chapter 1. Marine biomaterials: resources, categories and applications -- Chapter 2. Cross-linked marine biopolymers for delivery of therapeutics -- Chapter 3. Chitosan and Chitooligosaccharides: Preparation, Characteristics and their Potential Application as Therapeutic Agents -- Chapter 4. Marine collagen for delivery of therapeutics -- Chapter 5. Marine Biopolymers for delivery of Gene -- Chapter 6. Hydrogel scaffolds based on alginate, gelatin, and 2-hydroxyethyl methacrylate for tissue regeneration -- Chapter 7. Tissue Engineering application of marine based materials -- Chapter 8. Marine biopolymer for theranostic applications -- Chapter 9. Marine biomaterials as carrier of drugs/biomolecules for management of bone disorders -- Chapter 10. Expanding Role of Marine Natural Compounds in Immunomodulation: Challenges and Future Perspectives -- Chapter 11. Marine origin Bioactive Peptides: novel advances in the therapeutic potential.
    Abstract: This book provides updated information on marine-based biomedical carriers and their therapeutic potential. Marine biomaterials and bio-based carriers show wide application in pharmaceutical and biomedical fields to deliver small and large molecules. Biomaterial-based composites, scaffolds, or matrix systems are sound systems for controlled and prolonged drug release in target sites and control the premature release of drugs or bioactive compounds. This book discusses essential topics such as the therapeutic potential of marine collagen, management of bone disorders, gene delivery, natural marine compounds in immunomodulation, theranostic applications, tissue engineering, and regeneration. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. Marine biomaterial-based systems are popular for tissue engineering and biomedical imaging. This book is ideal for industry experts, students, and researchers in pharmaceutical sciences and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 392 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811653742
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Medical care. ; Therapeutics. ; Neurology . ; Medicine Research. ; Biology Research. ; Pharmacology. ; Health Care. ; Therapeutics. ; Neurology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. A Complete Patent Analysis of Cannabis/Marijuana in Drug Delivery and Disease Conditions -- Chapter 2. Neuropharmacological Approaches to Modulate Cannabinoid Neurotransmission -- Chapter 3. Cannabinoids in Cancer: Cross-talk Between Cannabinoids and miRNAs -- Chapter 4. Cannabis As A Potent Therapeutic Agent For Pharmaceutical Drugs: Recent Advancement In Drug Discovery And Human Healthcare -- Chapter 5. Cannabinoid-Based Innovative Prophylactic and Therapeutic Interventions for Neuropathic Pain and Migraine -- Chapter 6. The Legality of Use and Consumption of Cannabis (Marijuana) in the United States of America -- Chapter 7. Cannabis in Healthcare: Ethnobotanical and Pharmaceutical Perspectives and Legal Status in Turkey and The Middle East -- Chapter 8. Understanding the Pharmacokinetics, Safety Profile, and Scope of the Concerned Issue to Evade the Consumption of Cannabis/Marijuana -- Chapter 9. Traditional Uses of Cannabis in The Middle East and The Pathway to Cannabis-Based Healthcare in Israel -- Chapter 10. Traditional and Modern Health Uses of Cannabis sativa L. in Africa and its Phytochemical and Pharmacological Profile -- Chapter 11. Traditional Claims on Cannabis: An Indian and Global Scenario -- Chapter 12. Cannabis (Bhanga) in Classical Text of Ayurveda: An Evidence-Based Rationale -- Chapter 13. Cannabis-Based Cosmetic Products and Their Uses -- Chapter 14. Cannabis as A Unique and Valuable Nutraceutical Formulation for the Current and Future Global Wellbeing -- Chapter 15. Traditional, Cultural, and Nutraceutical Aspects of Cannabis in India.
    Abstract: The book contains review articles providing a comprehensive overview of cannabis/marijuana’s diverse healing aspects in human healthcare (medicinal, nutraceutical, skincare, etc.). The research articles include the role of cannabis in cancer treatment, drug discovery, cosmeceutical potential, prophylactic and therapeutic use for treating neuropathic pain and migraine, pharmacokinetics, safety profile, and issues related to the consumption of cannabis/marijuana.Another salient feature of the book is a complete mapping and region- and sector-wise critical analysis of cannabis/marijuana patents on healthcare and future directions for the benefit of researchers and businesses/entrepreneurs interested in the rapidly advancing area of cannabis. The text describes cannabis/marijuana’s detailed legal aspects, production prospects, and applications for healthcare and recreational purposes in the USA. It traces the traditional roots of cannabis use in Turkey, Israel, the Middle East, Africa, and India. This unique compendium of articles will be useful as a reference book for students, researchers, academics, business houses, and all individuals interested in medicinal, nutraceutical, cosmeceutical, traditional, legal, and commercial aspects of cannabis usage.
    Type of Medium: Online Resource
    Pages: XIX, 319 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811688225
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Plant ecology. ; Plants Development. ; Plant diseases. ; Biotechnology. ; Plant biotechnology. ; Plant Science. ; Plant Ecology. ; Plant Development. ; Plant Pathology. ; Biotechnology. ; Plant Biotechnology.
    Description / Table of Contents: Acknowledgements -- Introduction -- Geographic location of research -- Research methodology -- How to use this book -- Future studies -- Selected bibliography -- Plant monographs -- Index of plant names and health conditions.
    Abstract: This book highlights the results from over a year of ethnobotanical research in a rural and an urban community in Jamaica, where we interviewed more than 100 people who use medicinal plants for healthcare. The goal of this research was to better understand patterns of medicinal plant knowledge, and to find out which plants are used in consensus by local people for a variety of illnesses. For this book, we selected 25 popular medicinal plant species mentioned during fieldwork. Through individual interviews, we were able to rank plants according to their frequency of mention, and categorized the medicinal uses for each species as “major” (mentioned by more than 20% of people in a community) or “minor” (mentioned by more than 5%, but less than 20% of people). Botanical identification of plant specimens collected in the wild allowed for cross-linking of common and scientific plant names. To supplement field research, we undertook a comprehensive search and review of the ethnobotanical and biomedical literature. Our book summarizes all this information in detail under specific sub-headings.
    Type of Medium: Online Resource
    Pages: XVI, 257 p. 30 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030489274
    Series Statement: Advances in Economic Botany,
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Paleontology . ; Plant ecology. ; Plants Evolution. ; Plant Science. ; Paleontology. ; Plant Ecology. ; Plant Evolution.
    Description / Table of Contents: Introduction -- The miracle of amber -- Floral characteristics -- Chapter1. Burmese amber flowers -- Chapter2. Baltic amber flowers -- Chapter3. Dominican amber flowers -- Chapter4. Mexican amber flowers -- General conclusions -- References.
    Abstract: While much attention has been given to animal life in amber, the remains of a variety of plants, including angiosperm flowers, also exist in fossilized resin. Presented here is a pictorial synopsis of 94 flowers that occur in four major amber deposits around the world. These deposits are from Burma (Myanmar), the Baltic area, the Dominican Republic and Mexico, and range in age from the mid-Cretaceous to the mid-Tertiary. The basic features of these flowers are presented and their relationship with existing plant lineages discussed. This work will be of interest to amber enthusiasts, plant taxonomists, plant morphologists, plant ecologists, plant evolutionists and plant paleontologists.
    Type of Medium: Online Resource
    Pages: XV, 215 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031090448
    Series Statement: Fascinating Life Sciences,
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Veterinary microbiology. ; Food science. ; Agriculture Economic aspects. ; Plant Science. ; Veterinary Microbiology. ; Food Science. ; Agricultural Economics.
    Description / Table of Contents: Chapter 1. Introduction -- Part I. The role of natural products and remedies in treating animal diseases -- Chapter 2. The pharmacological and nutritional significance of plant natural products: An alternative for animal health -- Chapter 3. Alternative antimicrobials - medicinal plants and their influences on animal infectious diseases -- Chapter 4. Herbs used for horses in British Columbia and Trinidad and Tobago -- Chapter 5. Plants for controlling parasites in goats -- Chapter 6. Ethnoveterinary practices for control of ticks in Africa -- Part II. Sociological aspects and considerations relating to documentation of ethnoceterinary medicine -- Chapter 7. Gender aspects and multiple contexts in ethnoveterinary practice and science -- Chapter 8. Towards a better understanding of African ethnoveterinary medicine and husbandry -- Part III. Ethnoveterinary medicine around the world -- Chapter 9. Ethnoveterinary medicine and medicinal plants used in the treatment of livestock diseases in Cameroon -- Chapter 10. Ethnoveterinary medicinal plants used in South Africa -- Chapter 11. Ethnoveterinary plants and practices for the control of ticks and tick-borne diseases in South Africa -- Chapter 12. Ethnoveterinary medicine: a Zimbabwean perspective -- Chapter 13. Ethnoveterinary medicine in the Maghreb -- Chapter 14. Natural remedies for animal health in Latin America -- Chapter 15. Local practice of cattle farming and ethnoveterinary medicine in Estonia: case study of Saaremaa and Muhumaa -- Chapter 16. Belarusian ethnoveterinary medicine: ritual practices and traditional remedies -- Chapter 17. The use of medicinal plants for animal health in the Spanish inventory of traditional knowledge -- Index.
    Abstract: The importance of a complementary approach to animal health is highlighted in this book, with core themes encompassing reviews of traditional veterinary medicine for common diseases afflicting livestock, as well as local practices in different areas of the world. The book includes chapters on ethnoveterinary medicine used to prevent and treat ticks and tick-borne diseases, infectious diseases and parasites. Ethnoveterinary practices in parts of the world which have not been comprehensively reviewed before are highlighted, including Estonia, Belarus and the Maghreb - the north-western tip of Africa. A fascinating account of African ethnoveterinary medicine and traditional husbandry practices is provided by a veteran in the field with a wealth of practical experience in the area. Neglected areas of research involve the relationship of ethnoveterinary medicine with environmental, ethical, cultural and gender aspects, and leading experts explore these issues. The book is intended to provide an informative compilation of current research and future prospects in ethnoveterinary medicine, which hopes to inform and encourage investigations in new directions. Sustainable development requires a concerted effort to combine indigenous knowledge systems with scientific research to improve animal health. This is the case not only in rural areas where access to orthodox veterinary health care may be limited, but also against the backdrop of antibiotic resistance and increased demand for alternative and complementary therapies to enhance the health of both production and companion animals. Students, academics and veterinary professionals will find this book a useful addition to knowledge on present and future aspects of ethnoveterinary research.
    Type of Medium: Online Resource
    Pages: XIII, 435 p. 48 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030322700
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drugs Design. ; Medicinal chemistry. ; Molecular biology. ; Pharmacology. ; Pharmaceutics. ; Structure-Based Drug Design. ; Medicinal Chemistry. ; Molecular Biology.
    Description / Table of Contents: Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies – Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery.
    Abstract: The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
    Type of Medium: Online Resource
    Pages: XV, 257 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030958954
    Series Statement: Computer-Aided Drug Discovery and Design, 1
    DDC: 615
    Language: English
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    Keywords: Botany. ; Fungi. ; Mycology. ; Microbiology. ; Food Microbiology. ; Medical microbiology. ; Biomaterials. ; Nanomedicine. ; Plant Science. ; Fungi. ; Food Microbiology. ; Medical Microbiology. ; Plant Materials. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Part 1-General Identity and Taxonomy -- Phoma: An Overview -- Phoma Diseases-Identification, Epidemiology and Management -- Taxonomical Evaluation of Phoma-History of Classification, Current Status and Future Directions -- Part 2-Diversity, Diseases and Host Range -- Biodiversity of the Genus Phoma in Different Habitats -- Phoma on Medicinal and Aromatic Plants -- Types of Plant Diseases Caused by Phoma Species and Their Integrated Management -- Plant Pathogenic Phoma Species: Host Range, Symptoms and Distribution -- Overview of Phoma-like Fungi on Legumes: Papilionaceous plants): Pea, Beans, Soybean, Chickpea and Faba Beans -- Vegetable Diseases Caused by Phoma SSP -- Part 3: Phoma Spp. as a Human Pathogen -- Phoma as an Infectious Pathogen in Medical Practice -- Part 4- Bioactivities and Nanotechnology -- Genus Phoma; A Review of Its Potential Bioactivities, Implications and Prospects -- Bioherbicidal Activity of Phoma macrostoma -- Fruitful Decade for Phoma Secondary Metabolites From 2011 to 2020: Chemistry, Chemical Diversity and Biological Activities -- Plant Growth Promoting Phoma spp. -- Biological Management of Plant Diseases by Non-Pathogenic Phoma spp. -- Endophytic Phoma: Potentials and Limitations -- Bioactive Secondary Metabolites of Endophytic Phoma: Biochemistry and Signifigance -- Exploitation of Phoma for Fabrication of Silver Nanoparticles.
    Abstract: This reference covers the taxonomy, diversity, bioactivity, and nanotechnology involved in the study of Phoma. It presents the most recent molecular taxonomic approach, secondary metabolites, combating microbial threats and biohazards, and its use in nanotechnology from a basic research to an applied perspective. Expert contributors provide the latest research and applications to present thorough coverage of an important genus in human and plant pathology and bio management. Addresses the key issues in enigmatic taxonomy of the genus Phoma, and provides the current trends in taxonomy Discusses different secondary metabolites, their bioactivities (antifungal, antibacterial, antiviral, antiprotozoal, cytotoxic and herbicidal, etc.) and formulations Presents the role of different Phoma spp. in nanobiotechnology for synthesis of nanoparticles Provides the fossil-based evolutionary trends in Phoma spp.
    Type of Medium: Online Resource
    Pages: XVII, 342 p. 62 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030812188
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Alternative medicine. ; Pharmacology. ; Medicinal chemistry. ; Physiology. ; Agriculture. ; Plant Science. ; Complementary and Alternative Medicine. ; Pharmacology. ; Medicinal Chemistry. ; Physiology. ; Agriculture.
    Description / Table of Contents: Chapter 1 The History of Cannabis -- Chapter 2 The Bioactive Components of Plants -- Chapter 3 Chemical Constituents of Cannabis -- Chapter 4 The Bioactive Components of Cannabis -- Chapter 5 Neurological Effects of Cannabis -- Chapter 6 Psychotropic Effects of Cannabis -- Chapter 7 The Analgesic effects of Cannabis -- Chapter 8 Cannabis and Perinatal Development -- Chapter 9 Cannabis and Multiple Sclerosis -- Chapter 10 Cannabis and Cancer -- Chapter 11 Cannabis and Parkinson’s disease -- Chapter 12 Cannabis and the Skin -- Chapter 13 Antiviral Activities of Cannabis -- Chapter 14 Alkaline Phosphatase Stimulation.
    Abstract: By examining historical applications of the compounds found in plants, this five-volume series serves as a reference for quality assurance, research, product development, and regulatory guidance of the compounds found in plant-based medicines. This work supports the growing consumers' interest in herbal medicine for wellness and health. Plant-Based Therapeutics, Volume 1: Cannabis sativa, the first in the series, covers a unique plant species and provides the framework to integrate its evidence-based scientific discoveries with healthcare therapies. Cannabis has been used in religious ceremonies and medical purposes for thousands of years. Cannabidiol (CBD), the main non-psychoactive component of Cannabis, was isolated in the 1940s, and its structure was established in the 1960s. In 1964 tetrahydrocannabinol (THC), the psychoactive component, was isolated. Cannabis has more than 500 components, of which 104 cannabinoids have been identified. Two of them, THC and CBD, have been the primary components of scientific investigations. They were approved by the FDA for chemotherapy-induced nausea and vomiting in 1985; for appetite stimulation in wasting conditions, such as AIDS, in 1992, and in 2018 for treating two forms of pediatric epilepsy, Dravet syndrome and Lennox-Gastaut syndrome. Beyond the indications for which cannabinoids are FDA-approved, the evidence reveals that cannabinoid receptors are present throughout the body, embedded in cell membranes, and are believed to be more numerous than any other receptor system. When cannabinoid receptors are stimulated, a variety of physiologic processes ensue. Thus, other constituents of Cannabis are extremely promising either as individual compounds or their potential synergistic or entourage effects in the treatment of numerous medical conditions. .
    Type of Medium: Online Resource
    Pages: XXI, 657 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031351556
    DDC: 580
    Language: English
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    Keywords: Botany. ; Plant biotechnology. ; Plant Science. ; Plant Biotechnology.
    Description / Table of Contents: Chapter 1. An Introduction to Haematococcus -- Chapter 2. Nutritional studies and optimization of biomass from unicellular microalgae Haematococcus sp.-Chapter 3. Abiotic stress factors and high astaxanthin accumulation in Haematococcus pluvialis -- Chapter 4. Haematococcus: Cultivation for Astaxanthin Production -- Chapter 5. Bottlenecks in the cultivation processes of Haematococcus pluvialis -- Chapter 6. Biochemistry of Haematococcus -- Chapter 7. Lipids, lipidomics and biosurfactants of Haematococcus -- Chapter 8. Genetic engineering approaches for Haematococcus: Recent developments in genome sequencing and strain improvement -- Chapter 9. Food and Food Packaging Technology -- Chapter 10 Algae Materials for Bionanopesticides: Nanoparticles and composites -- Chapter 11. Environmental Impacts Related to Upstream and Downstream Processing of Haematococcus pluvialis -- Chapter 12. Therapeutic potential of Haematococcus pluvialis in the field of drug delivery -- Chapter 13. Clinical applications of Haematococcus. - Chapter 14. In silico exploration of therapeutics in Haematococcus pluvialis -- Chapter 15. Algal Polymers, Proteins and Pigments for Industrial Applications -- Chapter 16. Valorising Haematococcus biomass for commercial applications -- Chapter 17. Biotechnological applications of Haematococcus: Future perspectives -- Chapter 18. Commercialization of Haematococcus-based products: Current status and future forecast -- Chapter 19. Bioenergy Applications of Haematococcus.-.
    Abstract: This book offers a comprehensive analysis of microalgal cultivation methods and optimization of astaxanthin production for various applications, including clinical uses, algae polymers, proteins and pigments, food applications and packaging, algae forming, cosmetics, and more. Microalgae are unicellular living forms and are the primary producers that play a major role in the ecosystem. Commercially, while many documents are available, some recent fields are yet to be explored. The book comprises 19 chapters contributed by experts and reviews the recent developments in the cultivation, harvest, and genetic engineering of H. pluvialis-derived astaxanthin. It also discusses their bottlenecks and challenges in commercial-scale production, as well as current and prospective global market. Current research supports the exploration of new topics and practical applications of microalgae and their products, which will also benefit academia. The book will be an important resource for researchers and industry, providing comprehensive knowledge on broad topics. Flow charts, updated methods, and colour images are included to help the readers' understanding.
    Type of Medium: Online Resource
    Pages: XIV, 359 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819929016
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Medical genetics. ; Human physiology. ; Pharmacology. ; Medical Genetics. ; Human Physiology.
    Description / Table of Contents: Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.
    Abstract: The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
    Type of Medium: Online Resource
    Pages: XII, 316 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031384370
    Series Statement: Handbook of Experimental Pharmacology, 279
    DDC: 615
    Language: English
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  • 68
    Keywords: Botany. ; Agriculture. ; Plant Science. ; Agriculture.
    Description / Table of Contents: Abiotic Stress in Plants: Socio-economic Consequences and Crop Plants Responses -- Plant Abiotic Stress Tolerance Mechanisms -- Biotechnology Strategies to Combat Plant Abiotic Stress -- Nanomaterials Fundamentals: Classification, Synthesis and Characterization -- Utilization of Nanobiotechnology in Modern Agriculture -- Contributions of Nano Biosensors in Managing Environmental Stresses under Climate Change Era -- Utilization of Nanobiotechnology to Alleviate Impact of Abiotic Stress in Crop Plants -- Green Synthesis of Nanoparticles Using Different Plant Extracts and their Characterizations -- Applications of Plant-Derived Nanomaterials in Mitigation of Crop Abiotic Stress -- Biosynthesis and Characterization of Microorganisms-Derived Nanomaterials -- Utilization of Nanofertilizers in Plant Tolerance to Abiotic Stress -- Role of Nanomaterials in Regulating Reactive Species as a Signaling Molecule of Abiotic Stress -- Role of Nanomaterials in Regulating Oxidative Stress -- Plant Stress Enzymes Nanobiotechnology -- Plant Stress Hormones Nanobiotechnology -- Effect of Nanoparticle on Plant Growth and Development -- Application of Nanobiotechnology in Overcoming Salinity Stress -- Application of Nanobiotechnology in Overcoming Drought Stress -- Application of Nanobiotechnology in Overcoming Temperature Stress -- Application of Nanobiotechnology in Overcoming Mineral Nutrients Stress -- Nanomaterials Combat Heavy Metals Toxicity by Modulating Oxidative Stress Pathways in Plants -- Nanonutrients: Plant Nutritive and Possible Antioxidant Regulators -- Impact of Nanomaterials Stress on Plants -- Biosafety of Nanomaterials for Plants to Coup with Stress Conditions -- Nanomaterials in Combating Plant Stress: An Approach for Future Applications.
    Abstract: This book provides up-to-date knowledge of the promising field of Nanobiotechnology with emphasis on the mitigation approaches to combat plant abiotic stress factors, including drought, salinity, waterlog, temperature extremes, mineral nutrients, and heavy metals. These factors adversely affect the growth as well as yield of crop plants worldwide, especially under the global climate change. Nanobiotechnology is viewed to revolutionize crop productivity in future. The chapters discuss the status and prospects of this cutting-edge technology toward understanding tolerance mechanisms, including signaling molecules and enzymes regulation in addition to the applications of Nanobiotechnology to combat individual abiotic stress factors. .
    Type of Medium: Online Resource
    Pages: XVII, 590 p. 98 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030736064
    DDC: 580
    Language: English
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  • 69
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Description / Table of Contents: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Abstract: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Type of Medium: Online Resource
    Pages: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031357879
    Series Statement: SpringerBriefs in Pharmaceutical Science & Drug Development,
    DDC: 615
    Language: English
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  • 70
    Keywords: Botany. ; Bioclimatology. ; Environment. ; Plant Science. ; Climate Change Ecology. ; Environmental Sciences.
    Description / Table of Contents: Part I Understanding and management of abiotic and biotic stress in plants -- 1. Plant responses under abiotic stress and mitigation options towards agricultural sustainability -- 2. Plant viruses: Factors involved in emergence and recent advances in their management -- 3. Crop plants under metal stress and its remediation -- 4. Exploiting host resistance in management of vascular wilt in major pulses of India -- 5. Atmospheric nitric oxide (NO) regulates ozone (O3)-induced stress in plants: Ally or Foe? -- 6. Brassinosteroids: A wonder growth regulator to alleviate abiotic stresses in plants -- 7. Structural and functional role of plant dehydrins in enhancing stress tolerance -- 8. Adaptation of microalgae to temperature and light stress -- 9. Halopriming: Sustainable approach for abiotic stress management in crops -- 10. Naturally growing native plants of wastelands: Their stress management strategies and prospects in changing climate -- 11. Vulnerability and resilience of sorghum to changing climatic conditions: Lessons from the past and hope for the future -- 12. Recent updates in plant disease management -- 13. Heat stress in wheat: Impact and management strategies towards climate resilience -- Part II Potential of microbes in plant stress management -- 14. Plant-microbe interactions in combating abiotic stresses -- 15. Cadmium stress management in plants: Prospects of plant growth promoting rhizobacteria -- 16. Harnessing the power of microbes to overcome heavy metal stress in crop plant -- 17. Halotolerant plant growth promoting rhizobacteria: A futuristic direction to salt stress tolerance -- 18. Outside the cell surface: Encoding the role of Exopolysaccharide producing rhizobacteria to boost the drought tolerance in plants -- 19. Potential of plant growth promoting rhizobacteria for enhancement of plant growth and its role in improving soil health under abiotic stress -- 20. Soil application of plant growth promoting fungi for sustainable agriculture in the new decade -- 21. Deep insights into the role of endophytic fungi in abiotic stress tolerance in plants -- 22. Post-green revolution degradation of agricultural land in India: Role of mycorrhizae in the sustainability of agriculture and ecosystems -- Part III Strategies and technological advances for crop improvement -- 23. Integrated OMICS approaches to ameliorate the abiotic stress in Brassica napus -- 24. Proteomics – A powerful tool for understanding saline stress response in germinating seed -- 25. Role of secondary metabolites and prospects of engineering secondary metabolite production for crop improvement -- 26. Interventions of nanotechnology for the growth and stress tolerance in crop plants -- 27. Remote Sensing Technology: A new dimension in the detection, quantification and tracking of abiotic and biotic stresses.
    Abstract: This book presents an inclusive approach to deal with plant stresses in light of recent technological advances. As we have entered into a new decade, researchers and scientists should review and evaluate the recent findings in the field of plant stress management and visualize what we need to focus upon in the near future to increase crop yield. Above all, global climate changes present the greatest challenges of all time for plant scientists. In this context, the book highlights the recent findings and future perspectives in crop improvement to the faculties, scientists, research scholars, and postgraduate students. Major features of the book include an inclusive approach in understanding the mechanism of stress tolerance; recent advances and innovations in the field of allied disciplines like microbiology, molecular biology, biotechnology, plant breeding, nanobiotechnology, etc., for improving plant stress tolerance; and illustrative sketches to convey the mechanism and strategies of stress alleviation.
    Type of Medium: Online Resource
    Pages: XV, 457 p. 54 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030953652
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 580
    Language: English
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  • 71
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    DDC: 615
    Language: English
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  • 72
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    DDC: 615
    Language: English
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  • 73
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pharmacology.
    Description / Table of Contents: 1. Methods for Population Research on Substance Use and Consequences -- 2. Translational Molecular Approaches in Substance Abuse Research -- 3. Small Molecule Neuropeptide-S and Melanocortin Receptor Ligands As Potential Treatments for Substance Use Disorders -- 4. Emerging Insights into Mu Opioid Pharmacology -- 5. Behavioral Pharmacology of Drugs Acting at Mu Opioid Receptors -- 6. The Rise and Fall of Kappa-Opioid Receptors in Drug Abuse Research -- 7. Clinical Trials for Opioid Use Disorder -- 8. Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms -- 9. Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder -- 10. Molecular Mechanisms of Amphetamines -- 11. Clinical Trials for Stimulant Use Disorders: Addressing Heterogeneities That May Undermine Treatment Outcomes -- 12. Molecular Mechanism and Cannabinoid Pharmacology -- 13. Pharmacotherapies for Cannabis Use Disorders: Clinical Challenges and Promising Therapeutic Agents -- 14. Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence -- 15. Randomized Clinical Trials Investigating Innovative Interventions for Smoking Cessation in the Last Decade -- 16. Adolescent Vulnerability to Alcohol Use Disorder: Neurophysiological Mechanisms from Preclinical Studies -- 17. Medication Development for Alcohol Use Disorder: A Focus on Clinical Studies -- 18. Newly Emerging Drugs of Abuse.
    Abstract: The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use disorders. The first section is dedicated to methodology including population-based surveys, basic neuroanatomy, chemistry, molecular biology, behavioral models and brain imaging. The second section utilizes this methodology in research related to opioids, cocaine, marijuana, alcohol and nicotine. The book is aimed at both professionals (academics, clinicians, practitioners) and students or trainees.
    Type of Medium: Online Resource
    Pages: X, 502 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030336790
    Series Statement: Handbook of Experimental Pharmacology, 258
    DDC: 615
    Language: English
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  • 74
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pharmacology.
    Abstract: The Pharmacology of Taste is comprised of contributions by leading scientists from the field of chemosensory research, presented all together in the context of pharmacological principles of receptor function. The chapters cover all levels of scientific inquiry, from molecular and physiological mechanisms underlying taste signaling to its manifestation in overt behavior. The overarching objective of this volume is to inspire the application of concepts and methods of pharmacology to the study of the chemosenses.
    Type of Medium: Online Resource
    Pages: XII, 351 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031064500
    Series Statement: Handbook of Experimental Pharmacology, 275
    DDC: 615
    Language: English
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  • 75
    Keywords: Pharmacology. ; Allergy. ; Pharmacology. ; Allergology.
    Description / Table of Contents: Preface -- Part I: History and Epidemiology -- Part II: General Mechanisms -- Part III: Symptoms and Diseases -- Part IV: From Environmental Trigger to Disease Management -- Part V: Specific Mechanisms -- Part VI: Risk Factors -- Part VII: Diagnostics -- Part VIII: Allergy Prevention.
    Abstract: Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.
    Type of Medium: Online Resource
    Pages: XI, 500 p. 70 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030840488
    Series Statement: Handbook of Experimental Pharmacology, 268
    DDC: 615
    Language: English
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  • 76
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: Part 1: Quality by Design (QbD) -- Chapter 1. Pharmaceutical Quality by Design (QbD) overview and major elements -- Chapter 2. Fundamentals of design of experiments and optimization: designs for factor screening and data analysis in pre-response surface methodology -- Chapter 3. Fundamentals of design of experiments and optimization: experimental designs in response surface methodology -- Chapter 4. Fundamentals of design of experiments and optimization: data modeling in response surface methodology -- Chapter 5. Quality by Design in pharmaceutical product and process development -- Chapter 6. A Quality by Design update on nano-drug delivery systems -- Chapter 7. Control strategies of solid dosage forms by PAT tools -- Part 2: Analytical Quality by Design (AQbD) -- Chapter 8. Analytical Quality by Design Fundamentals, Compendial and Regulatory Perspectives -- Chapter 9. Analytical Target Profile (ATP) and Method Operable Design Region (MODR) -- Chapter 10: Quality by Design applications to development of analytical methods for quality control of pharmaceuticals -- Chapter 11. Design of Experiments Applied to the Extraction of Active Compounds. .
    Abstract: Written by twenty-five authors from academia, pharmaceutical industry and Pharmacopeias worldwide, this monograph covers the fundamentals and applications of Quality by Design (QbD) and Analytical Quality by Design (AQbD) in a practical and didactic manner. The book starts by describing the motivation and the urgent need for the implementation of the QbD framework in pharmaceutical development, along with the definition of its major elements: Quality Target Product Profile (QTTP), Critical Quality Attributes (CQAs), Critical Process Parameters (CPPs), Critical Material Attributes (CMAs) and the importance of using multivariate methods of Design of Experiments (DOE). The concept of life cycle and regulatory perspectives are discussed. Three chapters are entirely dedicated to DOE theory from screening to optimization designs. Moreover, a comprehensive discussion on modelling and data treatment is presented. Practical aspects of QbD and DOE for pharmaceutical product and process of different dosage forms is included, as well as a practical guide of the input process variables, material attributes, intermediate, and final quality attributes for the most representative pharmaceutical processes. Analytical Quality by Design (AQbD) is also deeply explored, including risk analysis, definitions of Analytical Target Profile (ATP), Method Operable Design Region (MODR) and the life cycle approach, taking into account the compendial and regulatory perspectives. A detailed example of a new chromatographic method for the quality control of a pharmaceutical topical product based on the AQbD procedure is shown. Finally, advanced statistical approaches and DOE methods for extraction studies of bioactive compounds are also presented. The vast amount of information offered in this book provides a comprehensive perspective on QbD, AQbD and DOE principles, essential tools for modern pharmaceutical and analytical development.
    Type of Medium: Online Resource
    Pages: X, 266 p. 62 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315053
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 10
    DDC: 615
    Language: English
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  • 77
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Neurosciences. ; Pharmacology. ; Neuroscience.
    Description / Table of Contents: Experimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson’s Disease: current state of affairs?” -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism.
    Abstract: “The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”.
    Type of Medium: Online Resource
    Pages: V, 158 p. 14 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874513
    Series Statement: Molecular and Integrative Toxicology,
    DDC: 615
    Language: English
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  • 78
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Botany. ; Environmental management. ; Environmental geography. ; Social sciences. ; Sustainability. ; Plant Science. ; Environmental Management. ; Integrated Geography. ; Society. ; Sustainability.
    Description / Table of Contents: Introduction -- Review of Literature -- Data Base and Methodology -- India’s Forest Cover, Forest policies and Acts and Impact of Governance on Forest Cover -- Institutions & Enforcement at Local Level -- Forest Dependency and Forest Governance in South Bengal and North Bengal Forest Divisions -- Conclusions and Policy Recommendations.
    Abstract: This book addresses quantitative assessment of forest governance and how local-level institutions work in governing efficient ways of forest resource management so that sustainable development of forest is ensured. The research is done at the micro-level as well as macro-level in India. The research presented here focuses on forest governance and institutions in the two forest divisions of West Bengal say South Bengal and North Bengal. The research covers 36 villages, 844 households, 10 Gram panchayat, 12 Beat offices, and 36 Forest protection Committees in West Bengal and also studies different local-level institutions like local communities/households; Joint Forest Management Committees (JFMC)/Forest Protection Committees (FPCs); Community Forest Management groups; Van Panchayats; Village Councils (schedule VI area) and Biodiversity Management Committees; Eco-development committees, NGOs and Self-Help Groups, and Panchayati Raj Institutions (PRIs). Chapters also address various issues like monitoring, enforcement, rule of law, transparency, accountability, participation, control of corruption, government effectiveness, regulatory quality, and sustainable livelihood in connection with the study of forest governance. This research is associated with different sectors like agricultural sector, forestry sector, informal sectors and rural development, etc., and involved multi-stakeholders. Particular attention is given on the policy-oriented research which is the cornerstone of SDG of 16. Developmental practitioners, government implementation agencies, researchers in environmental science and social science, and policymakers find this book appealing. .
    Type of Medium: Online Resource
    Pages: XIV, 231 p. 48 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031347467
    DDC: 580
    Language: English
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  • 79
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Background of Mulberry: Origin and Distribution, Domestication, Taxonomy, Cytology and Biodiversity -- Cultivation, Utilization and Economic benefits of mulberry in an Indian Context -- Mulberry Breeding for higher leaf Productivity -- Mulberry genome analysis: Current status, challenges, and future perspective -- Relationship between genome size and ploidy level in mulberry -- Transcriptomics: Current status and future prospects for identifying trait specific genes in mulberry -- Proteomics in mulberry -- Current status and importance of DUS testing in Mulberry -- Molecular diagnostics of soil borne and foliar diseases of mulberry: Present trends and future perspectives -- Transgenic Mulberry (Morus spp.) for Stress Tolerance: Current Status, Challenges and Future Perspectives -- Application of mulberry and mulberry silkworm by products for medical use -- Application of green synthesized nanoparticles in sustainable mulberry production: current trends and future perspectives -- Future Perspectives of Mulberry Genomic Research.
    Abstract: This book is the first comprehensive compilation of current knowledge on mulberry (Morus L.) covering botany, cytogenetics, biodiversity, genetics and breeding, tissue culture and genetic transformation, biotic and abiotic stresses, molecular mapping, QTL identification, whole genome sequencing and elucidation on functional genomics. As mulberry is one of the most economically important trees in Asian countries, it has attracted the attention of both academicians as well as industrialists. Being highly heterozygous due to long juvenile life coupled cross pollination among species, the genetics of this important crop species is yet to be unravelled. Nonetheless, the recent success of sequencing the genomes of haploid and diploid domesticated species has ushered in an era of intense molecular and genetic research to understand this crop well for its better utilization for mankind. In this book, efforts have been made to bring together key information on origin and distribution, taxonomy, morphological features, economic importance, abiotic stress responses, disease and pest resilience, current breeding strategies and their constraints, progress and prospects of gene mapping, elucidation of genes controlling metabolic and physiological pathways, and their utilization in crop improvement which are elaborated in about 250 pages over 13 chapters authored by globally leading experts on the species presented. This book is useful to the sericulture community in the world in general and students, teachers, and scientists in the academia for forage and fruit production, genetics, breeding, pathology, entomology, physiology, molecular genetics, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful to seed and biofuel industries.
    Type of Medium: Online Resource
    Pages: XIX, 298 p. 37 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031284786
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 80
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: Preface -- Abbreviations -- Chapter 1 – Why you need this book and why I wrote it -- Chapter 2 – What you need to do before you write a grant -- Chapter 3 – The idea -- Chapter 4 – Go solo or collaborate? -- Chapter 5 – What the entrepreneur needs to know -- Chapter 6 – The grant package -- Chapter 7 – The main event – writing it -- Chapter 8 – Edit / Polish / Shine / Repeat -- Chapter 9 – Are you ready to submit it? -- Chapter 10 - Post submission steps to win the grant -- Afterthoughts -- Index -- About the Author.
    Abstract: As an academic or a small business owner, you will need to write grants at some point in your career. Writing them though is not enough, what you also need to know is how to win grants. Much has been written about writing grants, the mysterious special ability called ‘grantsmanship’, so it occurred to me that there is a need to come at this differently and spill the beans. The difficulty in getting a grant, in particular an NIH grant like an R01 in the USA is often described, it is competitive and gets tougher every year. Your proposal therefore must stand out, it must connect with the reviewers. This is true for all types of grants, give the reviewer what they want always. But also, you need to connect to the program officer, the committee that ultimately makes funding decisions and you must take care of a myriad of other details outside of the main event which is describing the “science”. This means you cannot rely on just out-writing the competition, it is more than that as you have to out-think, out-strategize and out-schmooze them. If you have been continually funded for decades that is terrific, but if you want to keep being funded there is no guarantee what got you there will keep you there. What was a hot technology 4-5 years ago is not the new thing anymore, you will need to do something different, but what? You therefore need to not only think about writing great grants, you need to put it into practice and win them. Having written and won grants from the NIH and DOD over the past 17 years (and longer by the time you read this) I possess a valuable perspective. Each grant and study section will be different. Whether a big or small grant it does not seem to make a difference the reviewers will critique your efforts, they may not like it, they may reject your ideas or they may love it. You have some small degree of control until the proposal leaves your hands or more correctly you click ‘submit’. You will need to differentiate your grant from the hundreds of others in many ways, but you cannot change who you are, your history so how you describe yourself and team will also have an impact. You could spend hundreds of hours on your proposal or just a day and the outcome might still be the same. This small book is a summary of my own personal experiences and will provide some advice that will help you learn how to do a better job of winning grants. This book is written by a scientist who writes the grants and develops commercial products; Provides a unique perspective on what you need to write better grants; Teaches you how to continually win grants; This book provides examples from the authors own grant applications; The reader will be inspired to start a company to win small business grants.
    Type of Medium: Online Resource
    Pages: XIX, 106 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031275166
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 17
    DDC: 615
    Language: English
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  • 81
    Keywords: Botany. ; Agriculture. ; Plants. ; Stress (Physiology). ; Plant Science. ; Agriculture. ; Plant Signalling. ; Plant Stress Responses.
    Description / Table of Contents: Gasotransmitters signaling in plants under abiotic stress: An overview -- Influence of gasotransmitters on the physiology of plants with respect to abiotic stress tolerance -- Gasotransmitters and omics for abiotic stress tolerance in plants -- Advancement in the biology of gasotransmitters: H2S, NO, and ethylene -- Hydrogen sulfide: An evolving gasotransmitter regulating salinity and drought stress response in plants -- Ethylene synthesis and redox homeostasis in plants: Recent advancement -- Nitric oxide and cellular redox homeostasis in plants -- The function of hydrogen sulfide in plant responses to salinity and drought: new insights -- Hydrogen peroxide and its role in abiotic stress tolerance in plants -- Interaction of ethylene and H2S in plant stress management.
    Abstract: This book deals with the gasotransmitters signaling in redox reactions and homeostasis for the adaptation of plants to unfavorable abiotic stress environments. There are lots of interesting chapters in this book that cover both research and educational objectives. This book serves as a reference illustrated book for all who are interested in the regulation of gasotransmitters and redox homeostasis in agriculture. Maintenance of redox homeostasis strengthens the potentiality of plants to resist abiotic stress conditions through the enhanced antioxidant system and the subsequent impact on other signaling molecules. The book presents novel outcomes and implications in plant biology concerning the study of different types of gasotransmitters signaling such as nitric oxide (NO), ethylene, hydrogen sulfide (H2S), etc. under diverse abiotic stresses in one place. The chapters of the book discuss the recent progress and current perspectives on the role of gasotransmitters relevance to plant functions and adaptations to abiotic stresses, the influence of gasotransmitters on the physiology of plants with respect to abiotic stress tolerance, gasotransmitters and omics for abiotic stress tolerance, advancement in the biology of gasotransmitters in regulating salinity and drought stress response in plants, new insights of gasotransmitters and cellular redox homeostasis in plants and the chapter also deliberate the emerging role of gasotransmitters in regulating redox homeostasis for plant stress management. This book is the first comprehensive book covering all aspects and advancements in the biology of gasotransmitters in redox homeostasis conferring different abiotic stress tolerance, from which readers from all backgrounds can get benefitted. This book will appeal to researchers, students, scientific societies, agriculturists, etc.
    Type of Medium: Online Resource
    Pages: XIV, 221 p. 20 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031308581
    Series Statement: Signaling and Communication in Plants,
    DDC: 580
    Language: English
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  • 82
    Keywords: Botany. ; Judaism. ; Religion and science. ; Arts. ; Plant Science. ; Judaism. ; Religion and Sciences. ; Arts.
    Description / Table of Contents: The Biology of the Citron -- Citron Genomics -- Citron Phytochemistry -- Selected Aspects of Commercial Production in Etrog Orchards -- Preserving Etrog Quality After Harvest: Doctrine and Practice -- Citron Arthropod Pests in the Mediterranean, Their Origin and Notes On Their Biology and Management -- Diseases of the Etrog Citron and Other Citrus Trees -- The Citron ( Citrus medica L.) in China -- The Citron in Italy and Its cultivation in Calabria -- The Citron in Corsica -- The Citron in the United States -- The Citron in Mediterranean Food and Beverages -- 'Fruit of the Goodly Trees’: The Talmudic Discourse on the Etrog Citron -- From Theophrastus to the Present: The Citron in Medicine -- The Etrog Citron in Art -- The Etrog Citron in Midrashic and Kabbalistic Literature -- From ‘An Etrog’ to ‘One's Etrog’: A Literary Analysis of S.Y. Agnon’s Story -- History of the Citron in Ancient Israel and the Near East -- The Etrog Citron Trail to the North: Genoa and Trieste -- The Corfu Etrog Citron Polemic -- The Grafted Etrog Citron Controversy -- Etrog Citrons of the Land of Israel in Modern Times.
    Abstract: This comprehensive book covers the theoretical and practical aspects of citron trees and fruit. The citron (Citrus medica L.), one of the three primary species ancestral to most citrus types, is used for traditional medicine and is highly revered in the Jewish religion during the Tabernacles feast, referred to by the name 'Etrog'. This book’s three sections address biology (botany, genomics, Chinese and Mediterranean citrons, diseases, pests, and horticulture), tradition (Talmudic discourse, mysticism, medicine, literature, art, food, and beverages) and history (archaeology, trade, grafting controversies); these sections are supplemented by a glossary and pictorial album. The 22 chapters, some new and some translated and considerably expanded from the 2018 Hebrew edition, were written by world-renowned specialists from Israel, Italy, France, the U.S.A., China and Australia. The book is written in an accessible scientific style aimed at a wide range of readers. .
    Type of Medium: Online Resource
    Pages: XVIII, 607 p. 228 illus., 196 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031257759
    DDC: 580
    Language: English
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  • 83
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Botany. ; Ecology . ; Biodiversity. ; Biotic communities. ; Population biology. ; Plant Science. ; Ecology. ; Biodiversity. ; Community and Population Ecology.
    Description / Table of Contents: 1 -- Introduction -- 2. Southern tropical and subtropical rainforests -- 3. Multi-faced southern seasonal tropics 3.1 Heterogeneity of the savanna biomes: a southern perspective -- 4. Southern mediterranean: an extratropical plant marvel -- 5. Dry face of the ‘wet hemisphere’: southern deserts and semideserts -- 6. Austral temperate forests: a biome-classification conundrum -- 7. Southern ‘steppes’ and other grassy oddballs -- 8. The biomes of the coldest corners of the World -- 9. Synthesis: A New Global Zonobiome System -- 10. Further Challenges and Research Agenda -- References.
    Abstract: This is the first comprehensive and critical evaluation of the biome (large-scale, functional biotic communities) patterns in the Southern Hemisphere. Revising the Heinrich Walter's zonobiome system for the Southern Hemisphere appeared as necessary because of the bioclimatic imbalance between the Hemispheres. This revision resulted in formulation of a new zonobiome system, considering the geographic peculiarities of both Hemispheres, hence creating a new, powerful tool of global nature-resource survey and conservation. The system has a potential to attract the interest of the global climate modeling community as the concept of biome (and associated hierarchical system) has a strong functional focus. All zonal biomes of the Southern Hemisphere are featured, and the major challenges we face in understanding their origins, structure, and functioning are discussed. The book contains a wealth of original data resulting from collation of bioclimatic data and vegetation mapping.
    Type of Medium: Online Resource
    Pages: XIV, 219 p. 71 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031267390
    Series Statement: Biome Ecology, 1
    DDC: 580
    Language: English
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  • 84
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Plant biotechnology. ; Metabolism, Secondary. ; Plants. ; Plant Science. ; Plant Biotechnology. ; Plant Secondary Metabolism.
    Description / Table of Contents: 1. Understanding the molecular mechanisms of orchid mycorrhizal symbiosis from genetic information -- 2. Breeding of orchids using conventional and biotechnological methods: Advances and future prospects -- 3. Biotechnological interventions and societal impacts of some medicinal orchids -- 4. Gene expression profiling in orchid mycorrhizae to decipher the molecular mechanisms of plant-fungus interactions -- 5. Exploring the potential of in vitro cultures as an aid to production of secondary metabolites in medicinal orchids -- 6. Ethnomedicinal uses, phytochemistry, medicinal potential and biotechnology strategies for the conservation of orchids from the Catasetum genus -- 7. Diversity and antimicrobial potential of Orchidaceae-associated fungal endophytes -- 8. Asymbiotic seed germination in terrestrial orchids: Problems, progress and prospects -- 9. Progress and prospect of orchid breeding: An overview.
    Abstract: This book provides comprehensive insights into the existing and emerging trends in orchid biology based on the findings of omics, high-throughput technology, biotechnology, molecular breeding, and genome editing approaches in orchids. It illustrates molecular mechanisms of orchid mycorrhizal symbiosis according to the recent achievements of transcriptomics and bioinformatics studies which accelerate the progress of orchid research with the aid of their high-throughput tools. In this book, a comprehensive view of orchid breeding was presented, and it includes fundamental methods as well as advanced strategies through the combination of several technologies such as genetic engineering, omics, computational biology, and genome editing. These resulting knowledge and tools are highly beneficial for obtaining novel and fascinating varieties in the orchid market which is a competitive industry of global trade. Another interesting content is the focus on the production of orchid bioactive compounds and their values in the field of ethnomedicine. Their sources chiefly came from secondary metabolites and can be enriched through elicitors and produced more efficiently by improved tissue culture protocols and bioreactors. In this edited collection, we provided space for presenting an updated review of in vitro seed germination which is a routine technology for well-trained researchers but can give a complete demonstration for the potential audiences including growers and research beginners. This book collects refined knowledge from a broad source of scientific literature by experts in the field of orchid research and surely is an adequate reference and textbook for students, teachers, and researchers. It includes methods and applications of orchid breeding technology which would gain high attention from growers, breeders, and the related fields of agriculture.
    Type of Medium: Online Resource
    Pages: XIV, 283 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819910793
    DDC: 580
    Language: English
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  • 85
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Abstract: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Type of Medium: Online Resource
    Pages: XVIII, 768 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978340
    DDC: 615
    Language: English
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  • 86
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Physiology. ; Cytology. ; Life sciences. ; Pharmacology. ; Physiology. ; Cell Biology. ; Life Sciences.
    Description / Table of Contents: Part I: Physiological Functions of Endo-lysosomal Cation Channels -- NAADP-Mediated Ca2+ Signalling -- NAADP-Dependent TPC Current -- NAADP-Evoked Ca2+ Signaling: The DUOX2–HN1L/JPT2–Ryanodine Receptor 1 Axis -- TPC Functions in the Immune System -- Lysosomal Ion Channels and Lysosome– 1 Organelle Interactions -- TRPML1 and TFEB, an Intimate Affair -- Lysosomal Potassium Channels -- Part II Structure and Composition of TPC and TRPML Channels -- Structure and Function of Plant and Mammalian TPC Channels -- A Structural Overview of TRPML1 and the TRPML Family -- Endo-Lysosomal Two-Pore Channels and Their Protein Partners -- Part III: Tools and Methods to Characterize Endolysosomal Cation Channels -- Electrophysiological Techniques on the Study of Endolysosomal Ion Channels -- The Plant Vacuole as Heterologous System to Characterize the Functional Properties of TPC Channels -- Expanding the Toolbox: Novel Modulators of Endolysosomal Cation Channels -- Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging.
    Abstract: This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level. .
    Type of Medium: Online Resource
    Pages: X, 304 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315237
    Series Statement: Handbook of Experimental Pharmacology, 278
    DDC: 615
    Language: English
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  • 87
    Keywords: Pharmacology. ; Therapeutics. ; Internal medicine. ; Fungi. ; Mycology. ; Microbiology. ; Medical microbiology. ; Pharmacology. ; Therapeutics. ; Internal Medicine. ; Fungi. ; Medical Microbiology.
    Description / Table of Contents: Chapter 1. Mushrooms as Promising Therapeutic Resources: Review and Future Perspectives -- Chapter 2. Medicinal Mushrooms for Respiratory Health -- Chapter 3. Therapeutic and Prophylactic Potential of Medicinal Mushrooms in COVID-19 -- Chapter 4. Influences of Edible Mushrooms on Dynamic and Diversity of Gut Microbiota -- Chapter 5. Mushrooms – From Traditional Remedies to the Modern Therapeutics -- Chapter 6. Biopharmaceutical Potential of Ophiocordyceps sinensis for Human Health -- Chapter 7. Anticancer Potential of Ganoderma lucidum and İts Relevant Modes of Action -- Chapter 8. Cognitive Enhancing Effects of Medicinal Mushrooms: A Potential Neuroprotective Implication in Dementias -- Chapter 9. Potential of Medicinal Mushrooms in Human Health and Welfare: An Overview -- Chapter 10. Mycotherapeutics Reduce Nephrotoxicity and Renal Diseases -- Chapter 11. Proteomic Research on the Therapeutic Properties of Medicinal Mushrooms -- Chapter 12. Cordyceps militaris (L.): Medicinal aspects in terms of ethnobotanical and pharmacological perspectives -- Chapter 13. Mycotherapeutics Affecting Dopaminergic Neurotransmission to Exert Neuroprotection -- Chapter 14. Biological Activities of Some Edible Mushrooms -- Chapter 15. Nephroprotective Effects of Four Ganoderma Species -- Chapter 16. Mechanisms Involved in Edible Mushrooms' Health Beneficial Effects -- Chapter 17. Mycotherapy (Medicinal Mushrooms) as a Potential Treatment for Epilepsy -- Chapter 18. Natural vs. Synthetic Psilocybin: The Same or Completely Different? -- Chapter 19. Preventative and Curative Properties of Reishi and Maitake Mushrooms in Cancer.
    Abstract: The book presents new and novel perceptions about ailments alleviating the effects of several mushroom species. Also, the book highlights the curative role of medicinal mushrooms on some peripheral and central diseases. Various chapters in the book (primarily reviews) have been dedicated to providing the therapeutic efficacy of mushrooms against respiratory illnesses, gut microbiota, COVID-19, dementia, epilepsy, mental ailments, cancers, cardiovascular, kidney-related diseases, and other common pathologies. Thus, medicinal mushrooms are current and future consumable healthcare products that usually exhibit nourishing properties and possess prophylactic and therapeutic values with minimal adverse effects and contraindications. The book focuses on Sustainable Development Goal (SDG 3) to promote healthy lives and well-being for all. Medical, pharmacy, nursing, and CAM (complementary and alternative medicine) students, practitioners, scholars, researchers, other healthcare professionals, and general readers are this book’s potential audience. The book can be adopted as a textbook for undergraduate and graduate courses so that the therapeutic potential of mushrooms can reach a wider audience. This book strives to create a new resource for the future use of medicinal mushrooms in various disorders. .
    Type of Medium: Online Resource
    Pages: XX, 509 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995507
    DDC: 615
    Language: English
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  • 88
    Keywords: Botany. ; Plant physiology. ; Agricultural genome mapping. ; Agriculture. ; Plant Science. ; Plant Physiology. ; Agricultural Genetics. ; Agriculture.
    Description / Table of Contents: 1. Importance of integrating physiological breeding to augment crop breeding -- 2. Stacking of complex traits through physiological pre breeding -- 3. Strategies to develop heat and drought tolerant wheat varieties following physiological breeding -- 4. Developing crop varieties by physiological breeding for improving plant nutrition -- 5. Role of Transpiration in Regulating Leaf Temperature and its Application in Physiological Breeding -- 6. Photosynthesis as a trait for improving yield potential in crops -- 7. Cuticular waxes and its application in crop improvement -- 8. Radiation use efficiency (RUE)-target for improving yield potential: Current status and future prospect -- 9. Application of Stable Isotopes in Crop Improvement -- 10. Root phenotyping for improved resource use efficiency in crops -- 11. Root system architecture and phenotyping for improved resource use efficiency in crops -- 12. Harnessing Root associated traits and Rhizosphere efficiency for Crop improvement -- 13. High throughput phenomics of crops for water and nitrogen stress -- 14. Metabolomics as a selection tool for abiotic stress tolerance in crops -- 15. Remote Sensing Algorithms and their Applications in Plant Phenotyping -- 16. Endophyte mediated crop improvement: Manipulation of abiotic stress‐specific traits -- 17. Impact of high temperature stress on selected food grain crops -- 18. Morpho-physiological basis of finger millet to withstand climatic extremes: A special reference to drought -- 19. Comprehending the physiological efficiency of millets under abiotic stress -- 20. Role of Next-generation sequencing in trait identification, genetic mapping, and crop improvement -- 21. Application of Artificial Intelligence and Machine Learning in Agriculture.
    Abstract: This book covers different physiological processes, tools, and their application in crop breeding. Each chapter emphasizes on a specific trait/physiological process and its importance in crop, their phenotyping information and how best it can be employed for crop improvement by projecting on success stories in different crops. It covers wide range of physiological topics including advances in field phenotyping, role of endophytic fungi, metabolomics, application of stable isotopes, high throughput phenomics, transpiration efficiency, root phenotyping and root exudates for improved resource use efficiency, cuticular wax and its application, advances in photosynthetic studies, leaf spectral reflectance and physiological breeding in hardy crops like millets. This book also covers the futuristic research areas like artificial intelligence and machine learning. This contributed volume compiles all application parts of physiological tools along with their advanced research in these areas, which is very much need of the hour for both academics and researchers for ready reference. This book will be of interest to teachers, researchers, climate change scientists, capacity builders, and policy makers. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, physiology, botany, ecology, and environmental sciences. National and international agricultural scientists will also find this a useful resource.
    Type of Medium: Online Resource
    Pages: XIV, 457 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811974984
    DDC: 580
    Language: English
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  • 89
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery.
    Description / Table of Contents: 1. Synthesis, self-assembly and functional chemistry of Amphiphilic block copolymers -- 2. Advances in polymer optimisation for enhanced drug delivery -- 3. Dynamics of Micelle Formation -- 4. Types of Polymeric Micelles for Controlled Drug Release -- 5. Drug Solubilization and Drug Release from Polymeric Micelles -- 6. Physical and Analytical Techniques used for the Characterization of Polymeric Micelles -- 7.Stimuli-sensitive polymeric micelles for biomedical applications -- 8.Nucleic acid-based micellar therapy for the treatment of different diseases -- 9. Polymeric micelles in the delivery of therapeutic phytoconstituents -- 10. Diagnostic applications of surface-engineered polymeric micelles -- 11. Ligand conjugated polymeric micelles for targeted delivery of drug payloads in cancer therapy -- 12. Polymeric Micelles in the Delivery of Proteins -- 13. Regulatory aspects for polymeric micelles -- 14. Toxicological and regulatory challenges in design and development of polymeric micelles -- 15. Stability of polymeric micelles and their regulatory status.
    Abstract: This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.
    Type of Medium: Online Resource
    Pages: XV, 294 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903610
    DDC: 615
    Language: English
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  • 90
    Keywords: Botany. ; Plant diseases. ; Fungi. ; Mycology. ; Microbiology. ; Plant biotechnology. ; Ecology . ; Plant Science. ; Plant Pathology. ; Fungi. ; Plant Biotechnology. ; Ecology.
    Description / Table of Contents: Chapter 1. Mycotoxins and Their Producers: Diversity, Side Effects and Control -- Chapter 2. Seed-Borne Mycoflora and Their Management -- Chapter 3. Rhizosphere Mycobiome: Roles, Diversity, and Dynamics -- Chapter 4. Phyllosphere Mycobiome: Diversity and Function -- Chapter 5. Plant Mycobiome in Sustainable Agriculture -- Chapter 6. Plant-Fungus Interactions in Rust Diseases -- Chapter 7. Rust Haustoria -- Chapter 8. Recent Advancement in Fungal Biocontrol Agents -- Chapter 9. New Perspectives on Fungal Siderophores -- Chapter 10. Biogenic Synthesis of Nanoparticles Mediated by Fungi -- Chapter 11. Plant Growth-Promoting Fungi for Growth Improvement and Resistance Induction -- Chapter 12. An Insight into Fungi in Forest Ecosystems -- Chapter 13. Recent Progress on Fungal Enzymes -- Chapter 14. Endophytic Fungi as Sources of Novel Natural Compounds -- Chapter 15. Symbiotic Relationships with Fungi: From Mutualism to Parasitism -- Chapter 15. Symbiotic Relationships with Fungi: From Mutualism to Parasitism -- Chapter 16. Roles and Benefits of Mycorrhiza -- Chapter 17. Mycorrhizal Networks: A Secret Interplant Communication System -- Chapter 18. Impacts of Climate Change on Plant Mycobiome. .
    Abstract: Plant mycobiome represents a diverse array of plant-associated communities of endophytic and epiphytic fungi. These communities fundamentally affect plant health, development, adaptation, and communication with the surrounding ecosystem. Furthermore, they have key roles in the establishment, diversification, productivity, and sustainability of different natural ecosystems. However, some of these communities are pathogenic for the plant itself or dangerous for the consumers, due to the production of mycotoxins. In other words, plant mycobiome represents two faces of a coin. This book aimed to explore contributions of the plant mycobiome in plant-environment interactions from different perspectives. Chapters of this book address numerous themes covering the recent advances in roles, diversity, and dynamics of these fungi as biocontrol agents, biofertilizers, growth promoters, and their secondary metabolites in the area of crop improvement for sustainability and biotechnology, as well as the plant pathogenic and toxigenic fungi. This book will be useful to postgraduate students, botanists, mycologists, ecologists, plant pathologists, and physiologists.
    Type of Medium: Online Resource
    Pages: XII, 496 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031283079
    DDC: 580
    Language: English
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  • 91
    Keywords: Botany. ; Environment. ; Ecology . ; Environmental protection. ; Civil engineering. ; Plant Science. ; Environmental Sciences. ; Ecology. ; Soil and Water Protection.
    Description / Table of Contents: Chapter. 1. Introduction to Phytosequestration - Strategies for Mitigation of Aerial Carbon Dioxide and Aquatic Nutrient Pollution -- Chapter. 2. Global Climate: Chronological Perspective -- Chapter. 3. Sources and Monitoring Tools of Atmospheric Carbon Dioxide -- Chapter. 4. Global Warming: Impacts of Temperature Escalation -- Chapter. 5. Carbon Capture and Storage -- Chapter. 6. Future Climate through the Window of Climate Models -- Chapter. 7. Societal Responses to Anthropogenic Climate Change -- Chapter. 8. Monitoring of Nutrient Pollution in Water -- Chapter. 9. Impacts of Nutrient Pollution -- Chapter. 10. Phytomediation of Nuisance Pollution.
    Abstract: Most imperative environmental concerns are Cultural eutrophication pertaining to industrialization and urbanization which lead to proliferation of weeds in aquatic environs disturbing these ecosystems. Alarming increase in CO2, CH4, CFC’s, N2O and water vapour in the atmosphere cause enhanced greenhouse effect, among all these CO2 is accountable for 55-60 % of total enhanced effect. Phyto- and Nutrient sequestration via plants helps storage of atmospheric CO2 in the vegetation to get rid of contaminants. Carbon and nutrient sequestration can be braided together for sustainable development goals. The chapters adopt the hierarchy as follows: significance of quality environs, quantification and bio-monitoring of culprit contaminants, the issues relevant to global warming and accelerated eutrophication and their ecological impacts followed by various sequestration technologies.
    Type of Medium: Online Resource
    Pages: XVII, 97 p. 9 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031269219
    Series Statement: SpringerBriefs in Environmental Science,
    DDC: 580
    Language: English
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  • 92
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Description / Table of Contents: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Abstract: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Type of Medium: Online Resource
    Pages: XIX, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995019
    DDC: 615
    Language: English
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  • 93
    Keywords: Pharmacology. ; Biochemical markers. ; Cytology. ; Analytical biochemistry. ; Pharmacology. ; Biomarkers. ; Cell Biology. ; Analytical Biochemistry.
    Description / Table of Contents: Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
    Abstract: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
    Type of Medium: Online Resource
    Pages: VIII, 384 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031268595
    Series Statement: Handbook of Experimental Pharmacology, 277
    DDC: 615
    Language: English
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  • 94
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Plant Science. ; Genetics and Genomics. ; Biotechnology.
    Description / Table of Contents: Reference genome sequence of flax -- Repeat DNA sequences in flax genomes -- Pale flax (Linum bienne): an underexplored flax wild relative -- Flax breeding -- QTL mapping: strategy, progress and prospects in flax -- Genetics of abiotic stress in flax. QTL and candidate genes for flax disease resistance -- Key stages of flax bast fiber development through the prism of transcriptomics -- Metabolomics and transcriptomics-based tools for linseed improvement.
    Abstract: The Flax Genome is a comprehensive compilation of most recent studies focused on reference genome, genetic resources and molecular diversity, breeding, QTL mapping, gene editing tools, functional genomics and metabolomics, molecular breeding via genomic selection, and genomic resources. The flax genome reference sequences and the new genome assemblies are presented. A list of flax QTL and candidate genes associated with more than 35 traits, including yield and agronomic, seed quality and fatty acid composition, fibre quality and yield, abiotic stress, and disease resistance traits, are summarized. A QTL- based genomic selection strategy and genome–editing tools are systematically introduced. In addition, huge amounts of flax genomic resources generated in the last decade are summarized. The book contains 13 chapters with about 390 pages authored by globally reputed researchers in the relevant fields to this crop The book is intended to be useful to students, teachers, and researchers interested in traditional and molecular breeding, pathology, molecular genetics and breeding, bioinformatics and computational biology, and functional genomics.
    Type of Medium: Online Resource
    Pages: XII, 294 p. 74 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031160615
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 95
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Plant anatomy. ; Biodiversity. ; Plant Science. ; Plant Anatomy and Morphology. ; Biodiversity.
    Description / Table of Contents: Part I – User manual and architectural concepts. Chapter 1. Introduction -- Chapter 2. How to use this book 6 -- Chapter 3. Architectural concepts and key to the models -- Part II. Identification keys -- Chapter 4. Key to the groups of families of trees and shrubs (groups 1 to 52) -- Chapter 5. Keys to families of trees and shrubs -- Chapter 6. Supplementary keys -- Chapter 7. Keys to the groups of families of lianas and woody epiphytic (groups 53 to 57) -- Chapter 8. Keys to families of lianas and woody epiphytes -- PART III. Description of the families -- Chapter 9. Acanthaceae to Asteraceae -- Chapter 10. Bignoniaceae to Buxaceae -- Chapter 11. Cactaceae to Cycadaceae -- Chapter 12. Dichapetalaceae to Dipterocarpaceae -- Chapter 13. Ebenaceae to Euphorbiaceae -- Chapter 14. Fagaceae -- Chapter 15. Gentianaceae to Goupiaceae -- Chapter 16. Hamamelidaceae to Humiriaceae -- Chapter 17. Icacinaceae s.l. to Irvingiaceae -- Chapter 18. Juglandaceae -- Chapter 19. Lamiaceae to Lythraceae -- Chapter 20. Magnoliaceae to Myrtaceae -- Chapter 21. Nyctaginaceae,- Chapter 22. Ochnaceae to Oxalidaceae -- Chapter 23. Pandaceae to Putranjivaceae -- Chapter 24. Rhabdodendraceae to Rutaceae -- Chapter 25. Sabiaceae to Symplocaceae -- Chapter 26. Tetramelaceae to Torricelliaceae -- Chapter 27. Ulmaceae s.l. to Urticaceae -- Chapter 28. Verbenaceae to Vochysiaceae -- Chapter 29. Zygophyllaceae s.l -- Chapter 30. Herbaceous versus arborescent habit in the families and orders of flowering plants - evolutionary trends.
    Abstract: This book provides an identification system permitting recognition of plant families in all seasons by means of morphological and macroanatomical features which are easily observable, such as bark, exudates, stems and leaves characters. Studies of forest vegetation may differ in their underlying objectives, but they all require taxonomic knowledge. The process of taxonomy begins with an inventory of the flora, which has been based to a large extent on reproduction-related organs, such as flowers and fruits. But, those are often difficult to observe and may not exist in the field at a given time. Unlike most such guides or keys, this book can be used anywhere in the tropics and provides, in a straightforward two or three-step process, identification to the level of families, which are now circumscribed according to molecular as well as morphological characters in the universally accepted scheme of the Angiosperm Phylogeny Group. Plant architecture is not a prerequisite theme for plant identification; however, we think that an introduction to this subject is not out of place in this book (architectural traits are taxonomically sound): it is now time for botanists working in the tropics to have an idea on how the whole organism keeps growing. Within the family accounts, there is information concerning important economic plants with notes on the larger genera and, particularly helpfully, discussion of families readily confused and how to separate them. Descriptions of the families rely on short diagnosis bolstered by many photographic pictures, lines drawings and extracts from the author’s field books, all showing features of plants as they are found in the forest.
    Type of Medium: Online Resource
    Pages: XVII, 494 p. 909 illus., 850 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031059421
    DDC: 580
    Language: English
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  • 96
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Proteins . ; Human physiology. ; Biological transport. ; Cell membranes. ; Pharmacology. ; Protein Biochemistry. ; Human Physiology. ; Membrane Trafficking.
    Description / Table of Contents: 1. Classification and Gene Structure of Aquaporins -- 2. Protein Structure and Modification of Aquaporins -- 3. Expression Regulation and Trafficking of Aquaporins -- 4. Transport Characteristics of Aquaporins -- 5. Non-transport Functions of Aquaporins -- 6. The Evolutionary Aspects of Aquaporin Superfamily -- 7. Aquaporins in Nervous System -- 8. Aquaporins in Cardiovascular System -- 9. Aquaporins in Respiratory System -- 10. Aquaporins in Digestive System -- 11. Aquaporins in Urinary System -- 12. Aquaporins in Reproductive System -- 13. Aquaporins in Immune System.-14. Aquaporins in Eye -- 15. Aquaporins in Skin -- 16. Aquaporins in Glandular Secretion -- 17. Aquaporins in Fetal Development -- 18. Aquaporins in Diabetes Insipidus -- 19. Aquaporins in Edema -- 20. Aquaporins in Obesity.-21. Aquaporins in Tumor -- 22. Aquaporin Inhibitors -- 23. Non-aquaporin Water Channels.-24. Methods to Measure Water Permeability.
    Abstract: This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions. In the second version, fourteen chapters will be updated base on the most recent research articles. Ten new chapters will be added.
    Type of Medium: Online Resource
    Pages: VIII, 365 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811974151
    Series Statement: Advances in Experimental Medicine and Biology, 1398
    DDC: 615
    Language: English
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  • 97
    Keywords: Botany. ; Biotechnology. ; Nanotechnology. ; Plant Science. ; Biotechnology. ; Nanotechnology.
    Description / Table of Contents: 1. Introduction: Impact of Nanotechnology on Plant Cell Biology -- Part I Cellular Mechanisms -- 2. Effect of Nanomaterials on Water and Solutes Translocation in Plants -- 3. Response of Plant Photosynthesis to Nanomaterials -- 4. Impact of Nanomaterials on Chlorophyll Content in Plants -- 5. Interactions of Nanomaterials with Plant Pigments -- 6. Impact of Nanomaterials on Plant Secondary Metabolism -- 7. Toxic Effects of Nanomaterials on Plant Cellular Mechanisms -- Part II Cellular Macromolecules -- 8. Interaction of Nanoparticles with Plant Macromolecules: Carbohydrates and Lipids -- 9. Interaction of Nanomaterials with Plant Macromolecules: Nucleic Acid, Proteins and Hormones -- 10. Influence of Nanomaterials on Non-Enzymatic Antioxidant Defense Activities in Plants -- 11. 2D-Nanosheets Based Hybrid Nanomaterials Interaction with Plants -- Part III Agricultural Implications -- 12. Nanomaterial Impact on Plant Morphology, Physiology and Productivity -- 13. Role of Nanomaterials in Improving Crop Productivity -- 14. Role of Nanomaterials in Plant Cell and Tissue Culture -- 15. Role of Nanomaterials in Improving the Nutritional Value of Crops -- 16. Role of Nanomaterials in Improving Crop Tolerance to Abiotic Stress -- 17. Plant Mediation to Tolerate Cadmium Stress with Selenium and Nano-selenium -- 18. Synthesis and Applications of Cellulose Nanomaterials Derived from Agricultural Waste and Byproducts.
    Abstract: This book focuses on the recent progress of nanotechnology with emphasis on the interaction between nanoparticles and plants on the cellular level. It is devoted to understanding the pathways of nanomaterials entry into plant cell and their influence on cellular organelle processes and influence on crop yield. It consists of 16 chapters grouped in 3 parts: Part I Cellular mechanisms, Part II Cellular macromolecules, and Part III Implications of nanomaterials. Chapters present the plant response to nanomaterial applications including morphological, physiochemical, and anatomical changes and their effect on plant growth and productivity. The book discusses the mechanisms of absorbance and translocation of nanoparticles and their interaction with the plant cellular biochemical compounds and organelles. It presents the current perspective of nanomaterials influence on cellular processes which include photosynthesis, photorespiration and pigment synthesis and accumulation. In addition, it provides current understanding of the impact of nanomaterials on cellular macromolecules including carbohydrates, lipids, nucleic acids, proteins, hormones, and antioxidant defense activities. Collectively, these processes and biochemical compounds have implications on crop yield. Chapters are written by globally recognized scientists and subjected to a rigorous review process to ensure quality presentation and scientific precision. Chapter begins with an introduction that covers similar contexts and includes a detailed discussion of the topic accompanied by high-quality color images, diagrams, and relevant details and concludes with recommendations for future study directions. Chapter "Impact of Nanomaterials on Plant Secondary Metabolism" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XV, 507 p. 73 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031208782
    DDC: 580
    Language: English
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  • 98
    Keywords: Botany. ; Biochemistry. ; Plant Science. ; Chemical Biology.
    Description / Table of Contents: Chapter 1. An overview of medicinal plants of the Asteraceae family and their impact on human health -- Chapter 2. Artemisia annua L.: Traditional uses, Phytochemistry and Pharmacological activities -- Chapter 3. Artemisia indica Wild.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 4. Arnica montana L.: Traditional uses, bioactive chemical constituents, and pharmacological activities -- Chapter 5. Aster tataricus L.f.: Ethnomedicinal uses, phytochemistry and pharmacological activities -- Chapter 6.Atractylodes lancea (Thunb.) DC.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 7. Carthamus tinctorius L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 8.Chrysanthemum morifolium Ramat.: A Medicinal Plant with Diverse Traditional Uses, Bioactive Constituents, and Pharmacological Activities -- Chapter 9.Crassocephalum crepidioides (Benth.) S.Moore: Traditional uses, chemical constituents and biological activities -- Chapter 10. Dolomiaea costus (Falc.) Kasana & A. K. Pandey: Ethnomedicinal uses, bioactive chemical constituents and Pharmacological activities -- Chapter 11.Eclipta prostata (L.) L.: Traditional use, phytochemistry and pharmacology -- Chapter 12. Helianthus annuus L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 13. Silybum marianum (L.) Gaertn.: Traditional uses, phytochemistry and pharmacological activities.
    Abstract: This book highlights 12 major plants in the Asteraceae family from the aspects of traditional uses as food and medicine, phytochemistry, and pharmacological activities. Asteraceae is one of the largest family of flowering plants comprising over 1,600 plant genera and 32,000 plant species. Plants belonging to this family have a long history of being used as medicinal plants for the treatment of various diseases. Many of them are also used in the preparation of foods, beverages, and also used in pharmaceutical and cosmetic industries. In addition, plants such as Artemisia annua have played an important role in the discovery of novel drugs. The book summarizes the traditional uses of the plants in the family Asteraceae and their scientific validation, which helps readers understand their relation and impact on human health. It also explains the Phytochemistry of the species and presents the pharmacological activities and mechanisms in detail. Understanding current scientific knowledge will help in the commercialization of products based on these plants and also helps to find the research gaps that should be fulfilled in the future for their optimal use. It also helps in increasing the awareness of the plant species related to conservation, cultivation, and sustainable utilization. This edited volume comprises chapters contributed by experts from around the world. .
    Type of Medium: Online Resource
    Pages: IX, 230 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811960802
    DDC: 580
    Language: English
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  • 99
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Biosystematics and Botanical Descriptions of Seabuckthorn (Hippophae Sp.) in India -- Genetic Diversity, Evolution and Biogeography of Seabuckthorn -- Current Status of Chromosome-based Gender Determination in Seabuckthorn -- Analytical Techniques for the Biochemical Profiling in Seabuckthorn -- Effect of Processing and Storage on Seabuckthorn Products -- Metabolomic Diversity of Seabuckthorn Collections from Different Geographical Regions -- Deciphering the Proteomes and Nanotechnological Potential of an Unexplored Plant Seabuckthorn -- Biotechnological Approaches for Seabuckthorn Improvement -- Repertoire of Molecular Markers and their Applications in Seabuckthorn -- Barcoding-based Identification of Hippophae species -- Transcriptome Sequencing and Analysis of Seabuckthorn (Hippophae Sp.) -- Mining of Microsatellites and Transcription Factors in Seabuckthorn (Hippophae Sp.) Transcriptomes -- Frankia – The Endo-micro-symbiont of Hippophae Sp -- Medicinal and Nutraceutical Properties of Seabuckthorn -- Molecular and Cellular Mechanisms of the Anti-oxidative Activity of Seabuckthorn (Hippophae rhamnoides L.) -- Knowing More About Seabuckthorn (Hippophae rhamnoides)- A Promising Source of Safe and Effective Medical Radiation Countermeasure -- Methods in Seabuckthorn Breeding -- Global Distribution of Seabuckthorn (Hippophae Sp.) Resources and their Utilization .
    Abstract: This work is the first compilation of comprehensive deliberations on botany, cytogenetics and sex determination, genetic resources and diversity, classical breeding, molecular markers and genome sequence resources, and application of omics technology including transcriptomics, proteomics, and metabolomics resources in the multipurpose medicinal plant seabuckthorn. The book also presents a detailed narrative on antioxidative, radioprotective nutraceutical, and medicinal applications of seabuckthorn products. A detailed treatment has been included on analytical techniques and processing technologies. Altogether, the book contains about 300 pages over 17 chapters contributed by globally reputed experts on the relevant field in this important plant species. This book will be useful to the research students, teachers, and scientists in the academia and private sector engaged in horticulture, genetics, breeding, molecular biology, biotechnology, and breeding. The book will also be a useful source for workers involved in the development of plant-based medicines, nutraceuticals, therapeutics, and cosmeceuticals and extension workers involved in the development of rural farmers and small-scale industries.
    Type of Medium: Online Resource
    Pages: XXIX, 368 p. 74 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031112768
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 100
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Plant Science. ; Genetics and Genomics. ; Biotechnology.
    Description / Table of Contents: Crocus sativus saffron: A 360 degree overview -- Reference genome of Saffron “The Golden condiment” -- “SaffronOMICS: Novel approaches towards putting saffron data at work” -- Bioinformatics for saffron-omics and crop improvement -- Genetic mapping and molecular markers in Saffron -- Soil Classification, Nutrient Management and Land Cover of Saffron Growing Areas of Kashmir Valley -- Cultromic and metabarcodic insights into saffron-microbiome associations -- “Saffron, bacteria and mycorrhiza” -- Diversity and bioprospection of fungal endophytic microbiome of Crocus sativus L. (saffron) -- Epidemiology and Management of Corm Rot of Saffron -- Pathogenicity and genetic diversity of microbes in Crocus sativus L. and various strategies combating diseases -- Tissue culture techniques for Saffron improvement -- Saffron production under control condition -- Saffron: Metabolomics and quality points of view -- Saffron in phytotherapy : Pharmocological properties and medicinal uses -- Economic Aspects of Saffron in the World -- Marketing prospects for Saffron in domestic market: the case of Moroccan PDO.
    Abstract: This book is about Saffron (Crocus sativus L.) that is the most expensive spice in the world. Though there are other books on saffron but none of them has comprehensive information on saffron genome, transcriptome, proteome, metabolome and microbiome. The book has been divided into five sections and 17 chapters that cover all the areas related to its cultivation, market & economy, genomics, transcriptomics, proteomics, metabolomics, tissue culture, microbiomics, metagenomics etc. In addition a chapter on molecular markers and their use in molecular genetic mapping in saffron that lacks genetic diversity as a sterile plant paves a way for selection of elite varieties based on the epigenetic variability. A section on in-vitro propagation elaborates on the corm production under controlled conditions. In summary this book encompasses most of the information available on this golden spice.
    Type of Medium: Online Resource
    Pages: XVIII, 300 p. 72 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031100000
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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