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  • 1
    Online Resource
    Online Resource
    Principles of Microbial Metabolism and Metabolic Ecology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Life sciences. ; Microbial ecology. ; Industrial microbiology. ; Microbial genetics. ; Microbiology. ; Life Sciences. ; Microbial Ecology. ; Industrial Microbiology. ; Microbial Genetics.
    Description / Table of Contents: Microbial Life on Earth, Metabolism, and Metabolic Diversity -- A Microbe’s Environment and Natural Selection -- Microbial Energetics -- Catabolism and Its Coupling to Anabolism -- Microbial Kinetics -- Mechanisms of Microbial Energy Conservation -- Prototypic Reactions of Prokaryotic Carbon Catabolism -- Metabolic Modules, Pathways, and Nodes of Intermediates -- Fermentative Metabolism -- Prototypic Reactions, Modules, and Pathways of C1 Catabolism.
    Abstract: This textbook examines the fundamental principles of microbial metabolism and how a microbe's ecology is intrinsically interwoven with and a consequence of its metabolism. Further, it answers many questions frequently asked by students, such as: What are the mechanistic connections between simple phenotypic traits, ecological patterns and microbial metabolism and diversity? In the process, readers will be introduced to essential topics like metabolism and metabolic pathways, flux of energy and nutrients, genome size and fitness, competition, selection and drift. Moreover, the book conveys fundamental principles that show students how to approach the field of microbiology from a different, more unifying angle, e.g., how microbes’ access to environmentally available energy resources and the specific metabolism involved lies at the root of every ecologically significant microbial speciation. This aspect, together with its special focus on metabolism and ecological implications, make the book a must-read for all students of microbiology.
    Type of Medium: Online Resource
    Pages: XVII, 338 p. 198 illus., 165 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031282188
    URL: https://doi.org/10.1007/978-3-031-28218-8
    DOI: 10.1007/978-3-031-28218-8
    DDC: 579
    Language: English
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  • 2
    Online Resource
    Online Resource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Metabolomics, Proteomes and Gene Editing Approaches in Biofertilizer Industry (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biotechnology. ; Botanical chemistry. ; Botany. ; Microbiology. ; Biotechnology. ; Plant Biochemistry. ; Plant Science.
    Description / Table of Contents: Chapter 1. Constrains in biofertilizer industry and future scopes -- Chapter 2. Present scenario: Status of biofertilizer industry in India -- Chapter 3. Mode of application of biofertilizer in crop fields -- Chapter 4. Carrier based Biofertilizers -- Chapter 5. Liquid biofertilizers -- Chapter 6. Interaction of efficient rhizospheric bacteria and response in farmer’s field -- Chapter 7. Enhancing productivity through multiple microbial inoculants -- Chapter 8. Challages in compatibility of microbial inoculants with agrochemicals -- Chapter 9. Microbial metabolite-based products for plant growth promotion -- Chapter 10. Microbes from wild plants: Challenges and opportunities to be used as inoculant -- Chapter 11. Fungal biofertilizers: present trends and future prospects -- Chapter 12. Endophytes as plant growth inducers: a whole new arena in the inoculant industry -- Chapter 13. Immobilization and co-mobilization: An unexploited biotechnological tool for enhancing efficiency of biofertilizers -- Chapter 14. Microbial biostimulants: Bioformulations for enhanced biofertilizer efficacy and sustainable crop management -- Chapter 15. Omics approaches in strain improvement and new vistas in next-generation biofertilizers -- Chapter 16. Metabolomics and proteomics behind plant growth promoting potential of rhizobacteria -- Chapter 17. Proteomics in shaping future of biofertilizer delivery technique -- Chapter 18. Application of nanosilica for plant growth promotion and crop improvement -- Chapter 19. Industrial sustainability: Economics, cost and bioavailability of biofertilizers -- Chapter 20. Phyllosphere engineering: tailoring leaf surface microbes for boosting plant tolerance. .
    Abstract: This edited book covers the major aspects of plant growth promoting bacteria and mechanisms underlining the phenotype in rhizobacteria. This book guides the researchers about the potential of plant growth promoting bacteria to be used as biofertilizers. The process of biofertilizer development and the process of testing its efficacy for commercial use and the potency is elaborated in this volume using suitable figures. The information in this book regarding the secretion of various secondary metabolites responsible for nutrient management is helpful for designing bioformulations that assist plant growth. This book provides substantial number of evidences that underlines the genomic basis of nutrient management by microbes. Essential information is provided regarding the genomic and proteomic background of the biofertilizers. The chapters in the book are divided into three sections. The first section of the book includes chapter 1-5 outlining the importance of rhizobacteria in elevating the nutrient levels in soil and augmenting the biotic and abiotic stress. Second section of the book includes chapter 6-11 elaborating the details about the biofertilizer, types of biofertilizer available and techniques involved in mass production of biofertilizers. Section third covers chapters from 12-15 providing the explicit information about metabolomics and proteomics basis of plant growth development. This collective work is distinct as it has focus on diverse emerging technologies which are high-throughput, scalable and applicable to different countries regardless of their socio-economic conditions. This book can improve the current state of knowledge and invoke researchers and innovators to take ahead the current inter-disciplinary knowledge into technologies that are readily available and effectively minimize hazards associated with chemical fertilizer.
    Type of Medium: Online Resource
    Pages: XIV, 402 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819935611
    URL: https://doi.org/10.1007/978-981-99-3561-1
    DOI: 10.1007/978-981-99-3561-1
    DDC: 579
    Language: English
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  • 4
    Online Resource
    Online Resource
    Edible Plants in Health and Diseases : Volume II : Phytochemical and Pharmacological Properties (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Abstract: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: IX, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649592
    URL: https://doi.org/10.1007/978-981-16-4959-2
    DOI: 10.1007/978-981-16-4959-2
    DDC: 615
    Language: English
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  • 5
    Online Resource
    Online Resource
    Sustainable Environmental Protection Technologies : Contaminant Biofiltration, Adsorption and Stabilization (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental policy. ; Sociology. ; Physical geography. ; Pollution. ; Microbiology. ; Environmental Engineering/Biotechnology. ; Environmental Policy. ; Sociology. ; Physical Geography. ; Pollution.
    Description / Table of Contents: Chapter 1 -- The importance of technogenesis and sustainable environmental protection technologies. Chapter 2 -- Natural and artificial biogeochemical barriers as natural technologies. Chapter 3 -- The sustainable natural materials and their role in waste management and soil contamination stabilizing. Chapter 4 -- The sustainable natural materials used for adsorbing contaminants from aqueous medium. Chapter 5 -- Biotechnologies as the sustainable environmental protection technologies. Chapter 6 -- The major properties of natural materials used in biofiltration systems. Chapter 7 -- Operational parameters of biofiltration systems required for efficient operation of components ensuring system’s sustainability. Chapter 8 -- Natural and inoculated microorganisms as important component for sustainability of biofiltration system. Chapter 9 -- The technologies of the sustainable environmental protection in real conditions in the case of biofiltration systems.
    Abstract: This book discusses the need for the development of sustainable environmental protection technologies to reduce the impact of environmental contaminants. Three levels of sustainable technologies are addressed. The first level involves the concept of sustainable technologies as natural technologies, or ecotechnologies, whereby contamination level is assessed based on the contamination footprint through the use of biogeochemical barriers (e.g. methods utilizing the bioaccumulation properties of plants). The second level concerns the use of sustainable natural materials, such as biochar, in environmental engineering systems, an approach that is used for analyzing the processes of adsorption and biofiltration, as well as immobilization of contaminants in soil. The third level discusses the optimal components necessary to achieve sustainability in environmental engineering systems, including system operation principles, structural solutions, and the synergies between various system components such as microorganisms. The book will be of interest to specialists of industrial enterprises engaged in environmental protection, as well as environmental system designers, stakeholders from environmental protection ministries and institutions, researchers, doctoral students and masters and bachelors of science in the field of environmental engineering.
    Type of Medium: Online Resource
    Pages: XXI, 645 p. 287 illus., 123 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030477257
    URL: https://doi.org/10.1007/978-3-030-47725-7
    DOI: 10.1007/978-3-030-47725-7
    DDC: 579
    Language: English
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  • 6
    Online Resource
    Online Resource
    Edible Plants in Health and Diseases : Volume 1 : Cultural, Practical and Economic Value (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. The Folklore Uses and Economic Importance of Some Selected Edible Medicinal, Plants Native to Oman. A Brief Review -- Chapter 2. Socio-economic Importance of Some Promising Edible Medicinal Plants from (Rajasthan) India -- Chapter 3. Traditional and Economic Valuation of Edible Plants Used for Treatment of Diabetes -- Chapter 4. Cultural and Socio-economic Perspective of Some Promising Edible Plants from Northern Pakistan -- Chapter 5. Medicinal Plants and their Contribution In Socio-Economic Upliftment of the Household in Gurez Valley (J&K) -- Chapter 6. Comprehensive overview of Some Edible Medicinal Plants from Kashmir Valley – Cultural, Economic and Pharmacological Importance -- Chapter 7. High Altitude Edible Plants: A Great Resource for Human Health and their Socio-economic Significance -- Chapter 8. Cultural, Practical and Socio-economic Importance of Edible Medicinal Plants Native to Central India -- Chapter 9. Cultural and Scio-economic Perspective of Some Promising Edible Plants from Uttarakhand Himalaya. Chapter 10. Edible Medicinal Plants from Chhattisgarh (India) and their Economic Significance -- Chapter 11. Ethno-botanical and Economic Significance of Edible Plants Used as Food by Tribal Community of the Western Himalaya -- Chapter 12. Cultural, Practical and Economic Value of Edible Plants used by Mizo Tribes of Mizoram -- Chapter 13. Isoflavones of Soy: Chemistry and Health Benefits -- Chapter 14. Account of Some Important Edible Medicinal Plants and their Socio-Economic Importance -- Chapter 15. Cultural, Practical and Economic Significance of Some Edible Medicinal Plants from Gilgit-Baltistan Pakistan.
    Abstract: The book provides significant information on some of the promising edible medicinal plants and how these possess both nutritive as well as medicinal value. The significance of these edible plants in traditional medicine, their distribution in different regions and the importance of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume focuses on the economic and culturally important medicinal uses of edible plants and a detailed survey of the literature on scientific researches of pharmacognostical characteristics, traditional uses, scientific validation, and phytochemical composition, and pharmacological activities. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits, as well as discussing how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists as well as all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: XI, 388 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811648809
    URL: https://doi.org/10.1007/978-981-16-4880-9
    DOI: 10.1007/978-981-16-4880-9
    DDC: 615
    Language: English
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  • 7
    Online Resource
    Online Resource
    Targeting Epigenetics in Inflammatory Lung Diseases (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Epigenetics. ; Respiratory organs. ; Physiology. ; Pharmacology. ; Epigenetics. ; Respiratory Physiology.
    Description / Table of Contents: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Introduction to Epigenetics -- Chapter 3._Epigenetic mechanisms in Inflammation -- Chapter 4. Epigenetic regulator of inflammatory gene expression -- Chapter 5. Epigenetics of Asthma -- Chapter 6_. Epigenetic optimization in chronic obstructive pulmonary disease (COPD -- Chapter 7. Epigenetics of Lung Cancer -- Chapter 8. Epigenetics of Pulmonary Tuberculosis -- Chapter 9. Epigenetics of Idiopathic Pulmonary Fibrosis -- Chapter 10. Epigenetics of influenza-A virus infection -- Chapter 11. Epigenetics of rhinovirus -- Chapter 12. Epigenetics of SARS-Cov2 (Covid-19) -- Chapter 13. Epigenetics of Haemophilus Influenzae -- Chapter 14. Future Prospects and Challenges -- Chapter 15. Targeting epigenetics in pulmonary arterial hypertension.
    Abstract: This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.
    Type of Medium: Online Resource
    Pages: XV, 266 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819947805
    URL: https://doi.org/10.1007/978-981-99-4780-5
    DOI: 10.1007/978-981-99-4780-5
    DDC: 615
    Language: English
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  • 8
    Online Resource
    Online Resource
    A Practical Guide to Environmental Biotechnology (2020)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Water. ; Hydrology. ; Soil science. ; Microbiology. ; Water. ; Soil Science.
    Description / Table of Contents: Chapter 1: General Guidelines of Laboratory Safety, Calculations Used In Laboratory Experiments, Basic Laboratory Glassware And Instruments -- Chapter 2: Analysis of Quality of Water and Its Nutrient Contents -- Chapter 3: Analysis of Quality of Soil and Its Nutrient Contents -- Chapter 4: Isolation, Culture and Biochemical Characterization of Microbes -- Chapter 5: Plant Tissue Culture Techniques and Nutrient Analysis.
    Abstract: This textbook provides practical guidelines on conducting experiments across the entire spectrum of environmental biotechnology. It opens with general information on laboratory safety, rules and regulations, as well as a description of various equipment commonly used in environmental laboratories. It then discusses in detail the major experiments in basic and advanced environmental studies, including the analysis of water and soil samples; the isolation, culture, and biochemical characterization of microbes; and plant tissue culture techniques and nutrient analyses. Each chapter features detailed method sections and easy-to-follow protocols, and offers guidance on calculations and formulas, as well as illustrative flow charts to assist with troubleshooting for each experiment. Given its scope, the book is an invaluable aid for laboratory researchers studying environmental biotechnology, and a rich source of information and advice for advanced undergraduates and graduates in the fields of environmental science and biotechnology.
    Type of Medium: Online Resource
    Pages: XI, 175 p. 145 illus., 76 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811562525
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-981-15-6252-5
    DOI: 10.1007/978-981-15-6252-5
    DDC: 579
    Language: English
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  • 9
    Online Resource
    Online Resource
    Role of Microbes in Sustainable Development : Human Health and Diseases (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Pharmacology. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Microbiology. ; Pharmacology. ; Medical Microbiology. ; Translational Research.
    Description / Table of Contents: 1. Microbial Diversity and Their Role in Human Health and Diseases -- Section I: Gut Microbes and Perspectives -- 2. Emerging Microbial Identification Technologies in the Era of Omics and Genome Editing -- 3. Gut Microbiome: Perspectives and Challenges in Human Health -- 4. Probiotics – A Healthy Treasure -- 5. Different Generations of Probiotics: An Effective Way to Restore Gut Homeostasis -- 6. Application Of Potential Microbial Biotechnology for Sustainable Human Health -- Section II: Emerging Technologies in Gut Microbiome Research -- 7. Emerging Technologies and Current Advances in Human Bacteriome Research -- 8. Emerging Microbial Technologies: Mitigating Challenges to Humanity -- 9. Modern Tools of Genome Engineering and Their Applications -- 10. Emerging Technologies to Investigate the Potential of Gut Microbiota in Human Health -- 11. Tools and Techniques for Exploring Hidden Microorganisms: A Potential Future of Human Health Diagnosis -- 12. Crispr-Cas Fundamentals and Advancements in Translational Biotechnology” -- Section III: Gut Microbiome and Metabolic Disorders -- 13. Microbiome and Human Health: From Dysbiosis to Therapeutic Interventions -- 14. Gut Microbiota and Its Role in Human Metabolic Disorders -- 15. Influence Of the Gut Microbiome on Cardiovascular Health and Hypertension -- 16. Role Of Microbiome in Reproductive Health: An Expanding Dimension -- 17. Role Of Bacteriocins in Modulation of Microbiome in Human Diseases -- 18. Emerging Role of Gut Microbiome in Cancer Immunotherapy -- 19. Microbial Secondary Metabolites: Targetting Tumors and Associated Challenges -- 20. Bacteria And Bacteria-Based Products in Cancer Therapy: Current Status and Future Advances -- 21. Communication With Gut Microbiota: An Emerging Strategy to Predict and Prevent Cancer -- 22. Insights in the Cross-Talk Between Microbiota-Gut-Brain Axis: A Focus On Alzheimers’s Disease -- Section IV: Association of Phages and Fungi with Gut Microbiome -- 23. Fungi As a Treasure Trove of Bioactive Compounds for Human Health -- 24. Reminiscing Phages in The Era of Superbugs -- 25. The Potential of Bacteriophages in Treating Covid-19 Associated Secondary Infections -- Section V: Diverse Roles of Microbiome -- 26. Role Of Microbes in Production of Vaccines -- 27. Microbial Induced Calcite Precipitation Approach Towards Sustainable Development -- 28. Microbial Functional Foods and Nutraceuticals -- 29. Synthesis of Nanoparticles by Microbes -- 30. Microbial Biopharmaceuticals in Urolithiasis Management and Treatment -- 31. Use Of Yeast In The Welfare Of Human and Their Applications -- 32. Photoautotrophic Microbes with Potential for A Super Health Food On This Planet -- 33 Autopsy and COVID-19 -- 34 COVID and their Impacts on Aquatic Systems: Is it a Solution for Environmental Resilience? .
    Abstract: This book examines the role of human microbiome in human health and diseases. The initial chapters present tools for genetic manipulation of gut microbiota and the therapeutic applications of engineered microbiota. They discuss the interaction between human microbiota and host in defining the prominent role of microbes in the development and progression of major human diseases. The book also summarizes the current applications and trends for the development, production and analytical characterization of recombinant therapeutic proteins in microbial systems. It also reviews the role of microbes in the production of vaccines and antibiotics. Further, the book presents bacterial products, including proteins, enzymes, immunotoxins and secondary metabolites, that target cancer cells and cause tumour regression. The chapters also discuss the critical role of gut microbiota dysbiosis in the pathogenesis of autoimmune disease and in bowel-related diseases. Towards the end, the book explores the role of intestinal microbiota in metabolic health and the pathogenesis of common metabolic disorders. It presents state-of-the-art insights into important aspects of United Nations—Sustainable Developmental Goal 3.
    Type of Medium: Online Resource
    Pages: XXII, 713 p. 55 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819931262
    URL: https://doi.org/10.1007/978-981-99-3126-2
    DOI: 10.1007/978-981-99-3126-2
    DDC: 579
    Language: English
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  • 10
    Online Resource
    Online Resource
    Protocols for Cyanobacteria Sampling and Detection of Cyanotoxin (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biology Technique. ; Microbiology Technique. ; Microbiology. ; Biological Techniques. ; Microbiology Techniques.
    Description / Table of Contents: Section 1. Isolation and cultivation methods for Cyanobacteria -- Chapter 1. Collection of toxic Cyanobacteria from fish sample -- Chapter 2. Identification of toxic blooms of cyanobacteria in fresh water (lake, ponds) habitat -- Chapter 3. Identification of toxic blooms of cyanobacteria in marine water habitat -- Chapter 4. Identification of toxic blooms of cyanobacteria in Mangrove forest -- Chapter 5. Identification of toxic blooms of cyanobacteria in Estuarine habitat -- Chapter 6. Identification of toxic blooms of cyanobacteria in Saltpan habitat -- Chapter 7. Sampling and Identification of toxic cyanobacteria in Landfill Leachate -- Chapter 8. Handling and processing of Cyanobacterial toxin containing pond and lake water samples -- Chapter 9. Isolation of toxin producing Cyanobacteria from aquatic samples with Anabaena -- Chapter 10. Isolation of toxin producing Cyanobacteria from aquatic samples- Anabaenopsis sp -- Chapter 11. Isolation of toxin producing Cyanobacteria from aquatic samples with Cylindrospermopsis sp -- Chapter 12. Isolation of toxin producing Cyanobacteria from aquatic sample with Nodularia sp -- Chapter 13. Isolation of toxin producing Cyanobacteria from aquatic samples with Nostoc sp -- Chapter 14. Isolation of toxin producing Cyanobacteria from aquatic samples with Schizotrix -- Chapter 15. Isolation of toxin producing Cyanobacteria from aquatic samples with Lyngbya -- Chapter 16. Isolation of toxin producing Cyanobacteria from aquatic samples with Raphidiopsis -- Chapter 17. Isolation of toxin producing Cyanobacteria from aquatic samples – Oscillatoria -- Chapter 18. Isolation of toxin producing Cyanobacteria from aquatic samples – Planktothrix -- Chapter 19. Analysis of Cyanobacterial species composition and variation analysis among toxic blooms -- Chapter 20. Confocal Laser Scanning Microscope (CLSM) Identification of Toxic Cyanobacteria from Algal Bloom -- Chapter 21. Determination of Cyanotoxin patterns in strains and species of cyanobacteria -- Chapter 22. Chemical and toxicological studies of the toxic freshwater cyanobacterium - Microcystis aeruginosa -- Chapter 23. Chemical and toxicological studies of the toxic freshwater cyanobacterium - Anabaena flosaquae -- Chapter 24. Risk assessment of microcystin in the water resources -- Chapter 25. Extraction and quantification of BMAA from water sample -- Chapter 26. Extraction and quantification of BMAA from fish tissue -- Chapter 27. Postmortem sampling of Cyanobacteria in the case of suspected Drowning -- Section II. Toxicity analysis of Cyanotoxin -- Chapter 28. Detection of Cyanotoxins using Vertebrate bioassays in Mice -- Chapter 29. Detection of Cyanotoxin toxicity in Fish -- Chapter 30. Detection of Cyanotoxins using Invertebrate bioassays in brine Shrimp -- Chapter 31. Identification of Cyanobacterial toxins from Lichen thalli -- Chapter 32. Detection of Cyanotoxins using Bacterial bioassays -- Chapter 33. Detection of Cyanotoxins – Bioassay using plants -- Chapter 34. In vitro assay for determining cyanotoxin using serological methods -- Chapter 35. In vitro assay for determining cyanotoxin using cell line method- Hepatotoxicity (cell lines- HepG2, CaCo2, and V79) -- Chapter 36. In vitro assay for determining cyanotoxin using cell line method- Neurotoxicity ( Neuro-2A neuroblastoma cell) -- Chapter 37. Genotoxicity of Cyanotoxins -- Chapter 38. In silico analysis of cyanotoxin using computational tools -- Section III. Cyanobacterial toxin Extraction, detection and quantification -- Chapter 39. Extraction of Cyanotoxins using filtration and other methods -- Chapter 40. Extraction of Cyanotoxin by filtration and other methods from Biological materials (animal tissue: fish and mussels) -- Chapter 41. Extraction and quantification of Nodularins from fish samples by LC-MS/MS -- Chapter 42. Extraction and quantification of Nodularins from Shrimp samples by ELISA -- Chapter 43. Extraction and quantification of Cylindrospermopsins from aquatic samples by ELISA -- Chapter 44. Extraction and quantification of Anatoxins from aquatic samples by HPLC with Fluorescence detection -- Chapter 45. Extraction and quantification of Saxitoxins from aquatic samples by LC-MS/MS -- Chapter 46. Extraction and quantification of Guanitoxin from aquatic samples by HPLC-MS -- Chapter 47. Detection of Anatoxins from aquatic samples by LC-MS -- Chapter 48. Detection of Guanitoxin from aquatic samples by HPLC-MS/MS -- Chapter 49. Detection of cyanotoxin in algal food and feed supplements using UHPLC-MS/MS -- Chapter 50. Rapid detection method of microcystin in water -- Section: IV. Advanced Methods in Cyanotoxins -- Chapter 51. Screening of polyketide synthase genes in the anatoxin-a producing cyanobacteria -- Chapter 52. NRPS and PKS-gene analysis in cyanobacteria using PCR -- Chapter 53. Identification of microcystin, nodularin synthatase gene clusters in toxic Cyanobacteria using anti SMASH pipeline -- Chapter 54. qPCR assay in sxtA gene in Saxiotoxin producing Cyanobacteria -- Chapter 55. qPCR assay for the detection of hepatotoxigenic cyanobacteria -- Chapter 56. Molecular detection of mcy genes in toxic cyanobacteria: Anabaena, Microsystis, Planktothrix -- Chapter 57. Molecular Imprinting Polymer (MIP) in the detection of Microsystin-LR -- Chapter 58. Molecular identification of the cyclic peptide hepatotoxins in Cyanobacteria -- Chapter 59. Molecular identification of microcystin synthetase genes mcyE in cyanobacteria using PCR -- Chapter 60. Molecular identification of cyr C gene in toxic Cyanobacteria in photobiont -- Chapter 61. Detection of nodularin producing cyanolichen by Polymerase Chain Reaction (PCR) -- Chapter 62. Discriminationof nodularin toxin producing strains from non-producing strains using PCR -- Chapter 63. Detection of cyanobacterial cell wall components by cellular signaling biosensors -- Chapter 64. Nanosensor devices on the detection of Cyanotoxin -- Chapter 65. Insilico insights into the Cyanobacterial genomes to reveal their metabolic interactions -- Chapter 66. CRISPR Gene Finding in the Genome of Oscillatoria sp. and Lyngbya sp. .
    Abstract: This protocol book provides detailed procedures for the isolation of cyanobacteria, extraction, quantification, and detection of cyanotoxins. It illustrates the sampling and processing of toxin-producing cyanobacteria in water and aquatic animal samples, detection of cyanotoxins from Anabaena, Anabaenopsis, Cylindrospermopsis, Microsystis, Microcystis, Nodularia, Nostoc, Schizotrix, Lyngbya, Raphidiopsis, Oscillatoria, Planktothrix in aquatic resources. It also covers toxicity analysis by various bioassay protocols, and in vitro and insilico analysis methods. The book also reviews the methods for cyanotoxin extraction, detection, and quantification by various tools including LC-MS/MS, HPLC, NMR, PCR, and HESI-MS/MS. A separate section is dedicated to the advanced methods in Cyanotoxin analysis including the Molecular Imprinting Method (MIM), Cellular signaling biosensor, Electrochemical sensor, Nanosensors, and screening of Polyketide synthase gene. The analysis of various toxin-producing genes like sxtA and mcy is also accounted for in this book. In a nutshell, the book gives comprehensive procedures about the basics and preliminary processes that are involved in sample collection to advanced methods incorporated into the well-explored and unexplored Cyanobacterial toxin. Consequently, this manual is useful for both beginners and advanced researchers, including postgraduate students, academicians, researchers, and scientists in the field of Cyanobacterial research.
    Type of Medium: Online Resource
    Pages: XXX, 508 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819945146
    URL: https://doi.org/10.1007/978-981-99-4514-6
    DOI: 10.1007/978-981-99-4514-6
    DDC: 579
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  • 11
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    Online Resource
    Viral and Fungal Infections of the Central Nervous System: A Microbiological Perspective (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Medical microbiology. ; Fungi. ; Mycology. ; Microbiology. ; Medical Microbiology. ; Fungi.
    Description / Table of Contents: Dedication -- Foreword I -- Foreword II -- Preface -- Acknowledgements -- Disclosure Statement -- List of Contributors -- About the Editors -- THEME 1 Introduction: An Insight into Central Nervous System (CNS) Infections -- Chapter 1 Etiology and Epidemiology of Central Nervous System Infections -- CHAPTER 2 Overview of Infective Syndromes of The Central Nervous System and its Coverings: Decoding Chameleons and Mimics -- CHAPTER 3 Diagnosis of CNS Infections Through a Systematic Approach -- CHAPTER 4 Immune Responses in Infections of the Central Nervous System -- THEME 2 VIRAL PATHOGENS: PATHOGENESIS, PATHOLOGY, DIAGNOSIS AND TREATMENT -- CHAPTER 5 Herpesvirus Infections of the Central Nervous System -- CHAPTER 6 Enterovirus-associated Meningoencephalitis and Enteroviruses in Patients with Acute Encephalitis -- CHAPTER 7 Encephalitic Arboviruses -- CHAPTER 8 Neurological Illnesses Involved in Human Immunodeficiency Virus and Human T cell Lymphotropic Virus Infections -- CHAPTER 9 Neurological Complications of Measles and Mumps -- CHAPTER 10 Rabies Encephalitis: A Disease Characterized by Complex Neuropathogenic Pathways and Diagnostic Difficulties -- CHAPTER 11 Miscellaneous CNS Viral Infections: Underappreciated Causes of Neurologic Disease -- THEME 3 FUNGAL PATHOGENS: PATHOGENESIS, PATHOLOGY, DIAGNOSIS AND TREATMENT -- CHAPTER 12 Neuro-infections Caused by Candida Species -- CHAPTER 13 Cryptococcosis of the Central Nervous System -- CHAPTER 14 Mold Infections of the Central Nervous System -- CHAPTER 15 Role of Dimorphic Fungi in CNS Infections -- CHAPTER 16 Melanized Fungi in CNS Infections -- CHAPTER 17 Miscellaneous CNS Fungal Infections -- THEME 4 FUTURE INSIGHTS INTO CENTRAL NERVOUS SYSTEM INFECTIONS -- CHAPTER 18 Advanced Microbiological Diagnostic Techniques in Viral Infections of the Central Nervous System -- CHAPTER 19 Advanced Microbiological Diagnostic Techniques in Fungal Infections of the Central Nervous System -- CHAPTER 20 Association of Viral and Fungal Infections of the CNS during Immunosuppression. .
    Abstract: This book covers topics related to viral and fungal infections of the central nervous system (CNS), with a multidisciplinary reach, discussing associated immunology, microbiological aspects, pathologies, timely management, and prevention. The book is structured into five broad sections. The first section provides the reader with valuable insights into the aetiologies and underlying pathophysiological mechanisms of neurological diseases, including host responses. It mentions all bacterial, fungal, parasitic, and viral causes of neuro-infections, along with rarer neuropathogenesis such as prions and mycoplasmas. The chapter also presents detailed epidemiology and prevalence of different CNS infections worldwide. It also reviews various infectious diseases that target the nervous system, such as focal lesions, meningitis, and neurological complications of venous sinus thrombosis. The next two sections delve deep into pathogen-specific diseases of the CNS, namely the viruses and fungi associated with neuro-infections. It mentions detailed excerpts on encephalitic viruses, long-term consequences of neurotropic viruses, mycological neuroinfectious, and even the emerging, less talked of viruses and fungi causing neurological disease. Topics such as principles of vigorous antifungal therapy and surgeries are also discussed in the chapter. The fourth section gives an insight on prospects for efficiently diagnosing and managing viral and fungal CNS infections, to tackle associated morbidities. Features that are often less documented, yet of considerable interest in current times, such as the role of immunosuppression in neurological infections and newer microbiological diagnostic strategies are covered. The last section uniquely provides clinicians with relatable case scenarios. Real case descriptions are included, such as cases of fungal meningitis and other difficult-to-diagnose infections produced by viruses. This book serves as a guide for neurologists, medical microbiologists, and clinical practitioners who deal with patients suspected of neurological infection.
    Type of Medium: Online Resource
    Pages: XXIII, 482 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819964451
    URL: https://doi.org/10.1007/978-981-99-6445-1
    DOI: 10.1007/978-981-99-6445-1
    DDC: 579
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  • 12
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    Microbial Biocontrol: Molecular Perspective in Plant Disease Management (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Molecular biology. ; Agricultural genome mapping. ; Agricultural biotechnology. ; Bioremediation. ; Microbiology. ; Molecular Biology. ; Agricultural Genetics. ; Agricultural Biotechnology. ; Environmental Biotechnology.
    Abstract: This book is exploring molecular insight of plant disease resistance, enhancing plant immunity as well as the latest omics or approaches in plant disease management. In the recent past, microbial strains or products frequently utilized to inhibit the growth of phytopathogen and disease management. However, it is well known that plants respond to numerous biotic and abiotic stresses by morphological, biochemical, and molecular mechanisms. But still there is much more to study about their molecular aspect of interaction between host- pathogens- biocontrol agents that will be helpful in formulation and applications of microbial antagonistic for effective management of phytopathogens. This book attempt to fill this gap in the literature. This book is of interest to teachers, researchers, agronomist, horticulturalist scientists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, microbiology, environment science.
    Type of Medium: Online Resource
    Pages: XI, 347 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819939473
    Series Statement: Microorganisms for Sustainability, 49
    URL: https://doi.org/10.1007/978-981-99-3947-3
    DOI: 10.1007/978-981-99-3947-3
    DDC: 579
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  • 13
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    Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    URL: https://doi.org/10.1007/978-981-99-6917-3
    DOI: 10.1007/978-981-99-6917-3
    DDC: 615
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  • 14
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    Diagnosis of Mycobacterium (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Diagnosis. ; Diseases. ; Internal medicine. ; Microbiology. ; Diagnosis. ; Diseases. ; Internal Medicine.
    Description / Table of Contents: Chapter 1. Introduction to Diagnosis of Mycobacterium -- Chapter 2. Clinical and Radiological Diagnosis of Tuberculosis -- Chapter 3. Pathology based Diagnosis of Tuberculosis -- Chapter 4. Assessment of Hematological and Biochemical Parameters in the Diagnosis and Prognosis of Tuberculosis -- Chapter 5. Different Methods of Microscopic and Bacteriological Diagnosis of Tuberculosis -- Chapter 6. Molecular Diagnosis of Tuberculosis -- Chapter 7. Diagnosis and Challenges of Pediatric Tuberculosis -- Chapter 8. Diagnosis of Latent Tuberculosis -- Chapter 9. The Future of Serology-Based Diagnosis for Tuberculosis in India -- Chapter 10. Point of Care (POC) Detection Technique for Mycobacterium -- Chapter 11. Recent Advances in the Diagnosis and Treatment of Non-tuberculous Mycobacteria Infection -- Chapter 12. Sensor and Nanotechnology based Diagnostics in the Field of Mycobacteriology -- Chapter 13. Non-tuberculous Mycobacterium Infections in Lung Disease and Medical Interventions -- Chapter 14. Laboratory Diagnosis of Zoonotic Tuberculosis: An Update.
    Abstract: This book covers all the aspects related to the laboratory diagnosis of Mycobacterium. Laboratory diagnosis includes microscopic to advance molecular diagnosis. Moreover, it deals with the methods used to detect antimycobacterial susceptibility tests and drug resistance.Chapters cover most potential methods and techniques from traditional to advanced future diagnostics for identifying tuberculosis, NTM, and latent TB infections. Also discussed are the challenges and opportunities in the diagnostic science of infectious disease. This book offers assistance to students, postgraduate medical students, researchers, medical practitioners, postdoctoral fellows, microbiologists, nurses, and public health officers working in tuberculosis control programs to understand various modalities for diagnosis and drug-resistance tuberculosis.
    Type of Medium: Online Resource
    Pages: XXIV, 258 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819956241
    URL: https://doi.org/10.1007/978-981-99-5624-1
    DOI: 10.1007/978-981-99-5624-1
    DDC: 579
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  • 15
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    Current Research Trends and Applications in Waste Management (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Refuse and refuse disposal. ; Bioenergetics. ; Microbiology. ; Waste Management/Waste Technology. ; Bioenergetics.
    Description / Table of Contents: Chapter 1 Emerging Frontiers of Microbes in Liquid Waste Management -- Chapter 2 Municipal wastewater treatment by microalgae with simultaneous resource recovery: A biorefinery approach -- Chapter 3 An economic and sustainable method of bio-ethanol production from Agro-waste: A waste to energy approach -- Chapter 4 Sewage and wastewater management to combat different mosquito vector species -- Chapter 5 Keratinase role in management of poultry Waste -- Chapter 6 Biomedical Waste: Impact on Environment and its Management in Health Care Facilities -- chpater 7 Microbial intervention in waste remediation for Bio-energy production -- Chapter 8 Role of Microorganisms in Biogas Production From Animal Waste and Slurries -- Chapter 9 Bioelectricity generation from organic waste using microbial fuel cell -- Chapter 10 Bioremediation: Remedy for Emerging Environmental Pollutants -- Chapter 11 Rhizoremediation: A Plant Microbe Based Probiotic Science -- Chapter 12 Microbial fermentation system for the production of biopolymers and bioenergy from various organic wastes and by-products -- Chapter 13 Nanotechnology: Opportunity and Challenges in Waste Management -- Chapter 14 ‘Omics’ approaches for structural and functional insights of ‘Waste to Energy’ Microbiome.
    Abstract: This book covers latest information on organic and inorganic waste management, and how the waste can be utilized as an energy source. An increasing world population and climate change rate hint that environmental health needs a sustainable waste recycling system worldwide. Management of wastes material plays a substantial role in the environment and climate regulation. Chapters contain modern tools and techniques for managing inorganic, biomedical, municipality, and food waste. The title covers the role of contemporary microbiology and biotechnological tools in waste management and how these microbial agents can enhance waste degradation and bioenergy production. The book covers interesting topics such as bio-ethanol production from agro-waste, microbial fuel cells, biogas production from animal waste, nanotechnology in waste recycling, etc. The primary audiences are researchers, scientists, students, and policymakers interlinked with waste management and applied microbial sectors.
    Type of Medium: Online Resource
    Pages: VII, 402 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819931064
    URL: https://doi.org/10.1007/978-981-99-3106-4
    DOI: 10.1007/978-981-99-3106-4
    DDC: 579
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  • 16
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    Online Resource
    Photoprotective Green Pharmacology: Challenges, Sources and Future Applications (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Pharmacology. ; Pharmaceutics. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1: Radiation biology: historical background, sources and complications -- Chapter 2: Algal radioprotective phytochemicals: Sources and potential applications -- Chapter 3: Bio-prospecting of photoprotective compounds in algae -- Chapter 4: Unraveling fungal radioprotectants and their applications -- Chapter 5: Recent advances in metabolomics and molecular genomics for the production of photoprotective compounds -- Chapter 6: Bioprospecting and evolutionary significance of radioprotectors in non-flowering lower plants -- Chapter 7: Radioprotective phytochemicals: diversity, efficacy, application and commercialization -- Chapter 8: Impacts of climate alterations in the biosynthesis of defensive natural products -- Chapter 9: Cancer therapeutics: mechanism of action, radiation toxicity and drug formulation -- Chapter 10: Role of nanotechnology in the development of radioprotective formulations -- Chapter 11: Radioprotective effects of nutraceuticals and food products -- Chapter 12: Bioprospecting of radioprotective compounds in bacterial community -- Chapter 13: Pharmacology of synthetic and natural radioprotactants: application and consequences in cancer therapeutics -- Chapter 14: Immunochemistry: consequences and mechanism of protection in chemotherapeutics -- Chapter 15: Radioprootective therapeutics: recent trends and future applications.
    Abstract: This book illustrates the role of photoprotective and radioprotective metabolites from natural sources. Various classes of radioprotective metabolites derived from cyanobacteria, algae, fungi, bryophytes, pteridophytes, gymnosperms, and higher plants have been explained to reinforce the current knowledge in this field. In addition, the book elucidates the potential applications of these metabolites in pharmaceutics, cosmetics, and biomedical sciences that will help develop commercial products in modern anti-radiation therapeutics. Topics such as stress tolerance environmental strategies, evolutionary tendency, and biosynthetic route of radioprotective compounds for cost-effective large-scale industrial production of the metabolites are also covered in the book. This book will add to the understanding of radioprotective mechanisms and curative measures for various deleterious diseases leading to cancer development. This volume also offers the latest insights into current and upcoming issues that arise from solar and atomic radiations and their amelioration by inherent radioprotective mechanisms of green plants. This book benefits readers from academia, industry, colleges, and research students to better understand the impacts of various radiations and the development of radioprotective green compounds.
    Type of Medium: Online Resource
    Pages: XIII, 264 p. 62 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819907496
    URL: https://doi.org/10.1007/978-981-99-0749-6
    DOI: 10.1007/978-981-99-0749-6
    DDC: 615
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  • 17
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    Sex and Gender Effects in Pharmacology (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Immunology. ; Neurology . ; Endocrinology. ; Cardiology. ; Pharmacology. ; Immunology. ; Neurology. ; Endocrinology. ; Cardiology.
    Description / Table of Contents: Part 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer’s disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
    Abstract: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031426483
    Series Statement: Handbook of Experimental Pharmacology, 282
    URL: https://doi.org/10.1007/978-3-031-42648-3
    DOI: 10.1007/978-3-031-42648-3
    DDC: 615
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  • 18
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    Microbial products for future industrialization (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Agriculture. ; Biotechnology. ; Biology Technique. ; Microbiology. ; Agriculture. ; Biotechnology. ; Biological Techniques.
    Description / Table of Contents: Chapter 1.Microbial product commercialization: Lab to Industry -- Chapter 2.Assessment of microbes & microbial products for future industrialization -- Chapter 3.Design and operation of new microbial product biopocessing system -- Chapter 4.Industrial aspect of marine bioprocessing -- Chapter 5.Application of cutting age molecular biotechnological tools in microbial bioprocessing -- Chapter 6.Bio-refinery for microbial products -- Chapter 7.Bioprospecting of microbes for value generation from wastes -- Chapter 8.Emerging microbial enzymes for future industrialization -- Chapter 9.Bioethanol from microbial fermentation of prospecting biomass -- Chapter 10.Microbial biodiesel for future commercialization -- Chapter 11.Microbial production of bioactive compounds -- Chapter 12.Future microbial products for pharmaceuticals industry -- Chapter 13.Microbial pigments and paints for clean environment -- Chapter 14.Organic acids and solvents production from microbial fermentation -- Chapter 15.Microbial biomaterials and their industrial application -- Chapter 16.Advanced recombinant DNA technology for improved microbial product formation -- Chapter 17.Microbial products for bioremediation -- Chapter 18.Green synthesis of microbial nanoparticles -- Chapter 19. Electrochemically-active microorganisms -- Chapter 20.Techno-economic feasibility analysis of microbial product commercialization -- Chapter 21.Ethical issues of microbial products for industrialization.
    Abstract: This book “Microbial Products for Future Industrialization” focuses on the exploitation of various advanced microbial and molecular biology technologies and their associated processes, especially the microbial-molecular-chemical nexus, for the future industrialization of emerging new microbial products. The descriptions given in its chapters take the reader through an entire journey of new emerging microbial products from lab to industry and provide new information that has not yet been fully exploited for future industrialization steps. This volume is a great resource for readers seeking a more comprehensive material covering the technical, economic, and societal aspects that impact bioprocessing of microbial products at the industrial level along with biotechnological intervention for better production of microbial products in near future. This book also encompasses advanced and updated information as well as future directions for young researchers and scientists, and academics who are working in the field of microbial product production related to sustainability.
    Type of Medium: Online Resource
    Pages: XII, 411 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819917372
    Series Statement: Interdisciplinary Biotechnological Advances,
    URL: https://doi.org/10.1007/978-981-99-1737-2
    DOI: 10.1007/978-981-99-1737-2
    DDC: 579
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  • 19
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    Online Resource
    Evidence Based Validation of Traditional Medicines : A comprehensive Approach (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Abstract: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Type of Medium: Online Resource
    Pages: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581274
    URL: https://doi.org/10.1007/978-981-15-8127-4
    DOI: 10.1007/978-981-15-8127-4
    DDC: 615
    Language: English
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  • 20
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    Online Resource
    Therapeutic Applications of Dopamine D3 Receptor Function : New Insight After 30 Years Of Research (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Preface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson’s Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging.
    Abstract: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031230585
    Series Statement: Current Topics in Behavioral Neurosciences, 60
    URL: https://doi.org/10.1007/978-3-031-23058-5
    DOI: 10.1007/978-3-031-23058-5
    DDC: 615
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  • 21
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    Online Resource
    Food Microbial Sustainability : Integration of Food Production and Food Safety (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biology. ; Food science. ; Biotechnology. ; Medical microbiology. ; Microbiology. ; Biological Sciences. ; Food Science. ; Biotechnology. ; Medical Microbiology.
    Description / Table of Contents: Chapter 1. Role of Microorganisms in the Food Industry -- Chapter 2. Farming Microbes for Sustainable Food Production -- Chapter 3. Role of Microbes in Sustainable Food Preservation -- Chapter 4. Food Fermentation: Role of Microorganisms in Food Production -- Chapter 5. Benefaction of Probiotics for Human Health -- Chapter 6. Algal Protein: Future of Sustainable Food -- Chapter 7. Microbial Biofactories: A Promising Approach Towards Sustainable Omega-3 Fatty Acid Production -- Chapter 8. Lactic Acid Bacteria as a Source of Functional Ingredients -- Chapter 9. Applications of Microbial Enzymes in the Food Industry -- Chapter 10. Microbial Enzymes in Food Industries: Enhancing Quality and Sustainability -- Chapter 11. Sustainable Use of Microbes in Beverage Production -- Chapter 12. Economic Importance of Microorganism in Food Processing -- Chapter 13. Microbial Bioinformatics Approach in Food Science -- Chapter 14. The Beneficial Impact of Microbes in Food Production, Health, and Sustainability -- Chapter 15. Microbiome as a Key Player in Sustainable Food and Food Safety.
    Abstract: This book reviews all important aspects of Microbial sustainability in food production and food safety with the aim of shedding new light on these microbes through combined understanding of traditional and novel paradigms. The book is divided into three sections, the first of which reinterprets fundamentals of food microbiology, examining the beneficial aspects of microorganisms in food and microbial responses from food environments and preservation. The second section discusses recent advances in understanding of the sustainable food production, covering, for example, agriculturally important microbes, farming microbes, and fermentation. A wide range of bio-factory issues in food production are also addressed, before turning attention to contemporary food safety approaches in the context of novel assessment methods for microbiological food characterization, improving food safety and food quality, etc. The final section is devoted to public health and its importance of microorganisms in food processing as well as the economic importance of microorganisms as this is also an increasingly important area as we move toward microbial research advances.
    Type of Medium: Online Resource
    Pages: VIII, 333 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819947843
    URL: https://doi.org/10.1007/978-981-99-4784-3
    DOI: 10.1007/978-981-99-4784-3
    DDC: 579
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  • 22
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    Online Resource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
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  • 23
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    Online Resource
    Ethnopharmacology and Drug Discovery for COVID-19: Anti-SARS-CoV-2 Agents from Herbal Medicines and Natural Products (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Description / Table of Contents: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Abstract: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Type of Medium: Online Resource
    Pages: IX, 590 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936649
    URL: https://doi.org/10.1007/978-981-99-3664-9
    DOI: 10.1007/978-981-99-3664-9
    DDC: 615
    Language: English
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  • 24
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    Online Resource
    Micro-algae: Next-generation Feedstock for Biorefineries : Cultivation and Refining Processes (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biochemical engineering. ; Industrial microbiology. ; Biotechnology. ; Microbiology. ; Bioprocess Engineering. ; Industrial Microbiology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Microalgae Biomass Biorefinery: A Sustainable Renewable Energy Feedstock of the Future -- Chapter 2.Biorefinery approach for sustainable biodiesel and bioethanol production from microalgae -- Chapter 3.Microalgal promise to the next generation: A dual potential perspective as cosmeceuticals and biofuels -- Chapter 4.Microalgae-based technologies for removal of textile wastewater -- Chapter 5.Treatment of textile waste effluents using microalgae: a suitable approach for wastewater remediation and lipid production -- Chapter 6.The multifaceted microalgal approach to wastewater treatment to generate energy and essential chemicals -- Chapter 7.Heterotrophic micro-algal production system via utilization of wastewater in microalgal production -- Chapter 8.Recent developments in the enzymatic and bio-catalytic pretreatment of microalgae for efficient biofuel production -- Chapter 9.Innovative & Strategic upgrades in large scale Microalgal Culture Techniques -- Chapter 10.Advances on harvesting and extraction systems in micro-algal bio-refinery.
    Abstract: This edited book provides an account of past, present, and future constraints in microalgae-based biorefineries, emphasizing cultivation and refining processes. The book offers an insight into the recent advancements in the technologies and methods developed microalgae-based biorefinery for bioenergy and biochemicals production. The fast depletion of fossil fuels has forced researchers to move out of reliance on fossil fuels for the industrial and energy sector’s needs. Due to its rich protein and lipid content, microalgal biomass has been considered one of the suitable substrates for the biorefinery. Microalgal production and harvesting for biofuel and chemicals is a tedious task. Several technological advances have been observed in this area, thus systematically checking the viability of technology at laboratory scale and then moving to large scale production, harvesting, extraction, processing, and characterization is the main focus of the book. This book is equally beneficial for researchers and engineers in biomass-based biorefineries or the bachelors, master, or young budding graduate students as a textbook. .
    Type of Medium: Online Resource
    Pages: XVI, 250 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811907937
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-19-0793-7
    DOI: 10.1007/978-981-19-0793-7
    DDC: 579
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  • 25
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    Online Resource
    Herb-Drug Combinations : A New Complementary Therapeutic Strategy (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Abstract: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951251
    URL: https://doi.org/10.1007/978-981-19-5125-1
    DOI: 10.1007/978-981-19-5125-1
    DDC: 615
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  • 26
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    Online Resource
    Precision Medicine (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Internal medicine. ; Cancer. ; Pharmacology. ; Internal Medicine. ; Cancer Biology.
    Description / Table of Contents: Part 1. Pharmacogenomics -- Building evidence in RCTs Implementation of pharmacogenomics in healthcare in the UK -- Part 2. Precision medicine in clinical entities -- Precision medicine in therapy of non-solid cancer -- Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia -- Precision medicine in Asthma -- Precision medicine in Diabetes -- Precision Medicine in Antidepressants Treatment -- Precision Medicine in Neuropathic Pain -- Part 3. Techniques in Precision Medicine -- Imaging techniques in pharmacological precision medicine -- Challenges to use NGS data to optimize drug therapy -- Part 4. Economics -- Pharmacoeconomics in precision medicine. .
    Abstract: The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers including pharmacogenomics as well as advanced diagnostic tools have been successfully implemented in clinical practice in various fields leading to significant improvement of treatment successes. This volume gives an up-to-date overview on applications of precision medicine in various clinical entities, on advanced techniques as well as on economic considerations.
    Type of Medium: Online Resource
    Pages: X, 283 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031400476
    Series Statement: Handbook of Experimental Pharmacology, 280
    URL: https://doi.org/10.1007/978-3-031-40047-6
    DOI: 10.1007/978-3-031-40047-6
    DDC: 615
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  • 27
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    Online Resource
    Plant Relationships : Fungal-Plant Interactions (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Plant diseases. ; Microbial genetics. ; Plant physiology. ; Fungi. ; Mycology. ; Plants. ; Microbiology. ; Plant Pathology. ; Microbial Genetics. ; Plant Physiology. ; Fungi. ; Plant Signalling.
    Description / Table of Contents: Part I. Pathogenic Fungus – Plant Interactions -- Modulation of Host Immunity and Development by Ustilago Maydis -- RNA Dialogues in Fungal-Plant Relationships -- The Role of Tox Effector Proteins in the Parastagonospora Nodorum-Wheat Interaction -- Part II. Mutualistic Fungus – Plant Interactions -- Genomes of Arbuscular Mycorrhizal Fungi -- Diversity of Seed Endophytes: Causes and Implications -- Lichens and Their Allies Past and Present -- Lichen Fungal Secondary Metabolites: Progress in the Genomic Era Towards Ecological Roles in the Interaction -- Part III. Sensing and Signalling in Fungus-Plant Interactions -- Regulation of Plant Infection Processes by MAP Kinase Pathways in Ascomycetous Pathogens -- Role of pH in the Control of Fungal MAPK Signalling and Pathogenicity -- Role of Volatile Organic Compounds in Establishment of the Trichoderma-Plant Interaction -- Part IV. Regulation of Fungal Gene Expression and Development -- Epigenetic Regulation of Fungal Genes Involved in Plant Colonization -- Toward Understanding the Role of Chromatin in Secondary Metabolite Gene Regulation in the Rice Pathogen Fusarium Fujikuroi -- The Rice Blast Fungus Magnaporthe Oryzae Uses a Turgor-Dependent, Septin-Mediated Mechanism to Invade Rice -- Role of Light in the Life Cycle of Botrytis Cinerea -- Part V. Genomes and Evolution -- Species of Zymoseptoria (Dothideomycetes) as a Model System to Study Plant Pathogen Genome Evolution -- Accessory Chromosomes of the Fusarium Oxysporum Species Complex and Their Contribution to Host Niche Adaptation -- Part VI. Global Pandemics and Food Security -- Global Landscape of Rust Epidemics by Puccinia Species: Current and Future Perspectives -- Magnaporthe oryzae and Its Pathotypes: A Potential Plant Pandemic Threat to Global Food Security.
    Abstract: This fully revised 3rd edition provides a comprehensive overview of the biology of fungi associated with plants. Since the publication of the 2nd Edition in 2009, tremendous new knowledge has been gained in the field of fungal-plant interactions, which is reflected in the contributions of this book. World-leading scientists in the field provide authoritative insights into fungal-plant interactions covering the following main topics: Mutualistic and pathogenic fungal-plant interactions in natural and agricultural ecosystems Sensing and signalling in fungus-plant interactions Regulation of fungal gene expression and development Fungal genomes and evolution Global pandemics caused by fungal pathogens and their implications for food security This volume will be of great interest to both specialists and generalists. It is an indispensable resource for researchers, lecturers and students in microbiology, mycology, and plant sciences, as well as agriculture and biotechnology.
    Type of Medium: Online Resource
    Pages: XXII, 462 p. 70 illus., 62 illus. in color. , online resource.
    Edition: 3rd ed. 2023.
    ISBN: 9783031165030
    Series Statement: The Mycota, A Comprehensive Treatise on Fungi as Experimental Systems for Basic and Applied Research, 5
    URL: https://doi.org/10.1007/978-3-031-16503-0
    DOI: 10.1007/978-3-031-16503-0
    DDC: 579
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  • 28
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    Online Resource
    Mineral Formation by Microorganisms : Concepts and Applications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Industrial microbiology. ; Earth sciences. ; Microbial genetics. ; Microbiology. ; Industrial Microbiology. ; Earth Sciences. ; Microbial Genetics.
    Description / Table of Contents: Microbial Domains and Their Role in the Formation of Minerals -- Intracellular and Extracellular Bacterial Biomineralization -- Geophysical Monitoring and Characterization of Biomineralization Processes -- The Molecular Genetics of Microbial Biomineralization -- Silicate Minerals Induced by Microorganisms -- Non-Silicate Minerals (Carbonates, Oxides, Phosphates, Sulfur-Containing, Oxalates and Other Organic Crystals) Induced by Microorganisms -- Magnetosome Biomineralization by Magnetotactic Bacteria -- Factors Affecting Biomineralization -- Experimental Modeling of Carbonate Mineral Precipitation in the Presence of Cyanobacteria -- Key Applications of Biomineralization.
    Abstract: This book explains how microorganisms play a pivotal role in the formation of biominerals, including carbonates, silicate minerals and oxides. As readers will learn, these minerals may be produced either intracellularly or extracellularly in order to sustain microbial life. Experienced scientists from the field show that some of these biominerals can be produced in an active form, which involves direct enzymatic intervention to form precipitates. In addition, passive mineral formation can be mediated by the presence of dead cells. Readers from Microbiology and Biochemistry will appreciate the thorough coverage on various types of microbial mineral formation and their roles in microbial domains. Furthermore, they will benefit from the authors’ first-hand knowledge regarding common techniques for studying biomineral-producing microorganisms, factors affecting biomineralization, and the use of this process in biotechnological applications.
    Type of Medium: Online Resource
    Pages: VIII, 387 p. 62 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030808075
    Series Statement: Microbiology Monographs, 36
    URL: https://doi.org/10.1007/978-3-030-80807-5
    DOI: 10.1007/978-3-030-80807-5
    DDC: 579
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  • 29
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    Plant Microbiome for Plant Productivity and Sustainable Agriculture (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biotechnology. ; Microbial ecology. ; Microbiology. ; Biotechnology. ; Environmental Microbiology.
    Description / Table of Contents: Chapter 1. Fungal microbiomes The functional potential for plant growth promotion and opportunities for agriculture -- Chapter 2. Unearthing the Modern Trends and Concepts of Rhizosphere Microbiome in Relation to Plant Productivity -- Chapter 3. The Role of the Root Microbiome in the Utilization of Functional Traits for Increasing Plant Productivity -- Chapter 4. Crop microbiome for sustainable agriculture in special reference to nanobiology -- Chapter 5. Changes in plant microbiome in response to abiotic stress -- Chapter 6. Functional potential of plant microbiome for sustainable agriculture in conditions of abiotic stresses -- Chapter 7. The Beneficial Plant Microbial Association for Sustainable Agriculture -- Chapter 8. Microbiome of plants: The diversity distribution and their potential for sustainable agriculture -- Chapter 9. Decoding Beneficial Plant Microbe Association with Latest Techniques for Sustainable Agriculture -- Chapter 10. Phosphate solubilizing microorganisms Multifarious Applications -- Chapter 11. Bacillus and Streptomyces for management of biotic stresses in plants for sustainable Agriculture -- Chapter 12.Omic Route to Utilize Endophytes and their functional potentials in Plant Growth Advancement -- Chapter 13. Siderophore production in Iron uptake and plant biofortification -- Chapter 14. Plant microbiome diversity and potential for crops and sustainable agriculture -- Chapter 15. Endophytic phytohormone production and utilization of functional traits in plant growth promotion -- Chapter 16. Role of endophytic microorganisms in phosphate solubilization and phytoremediation of degraded soils -- Chapter 17. Techniques to Study Plant-Microbe Interactions that Leads to Efficient Sustainable Agriculture -- Chapter 18. Plant microbiome in agroecosystems for sustainable agriculture and environments. .
    Abstract: This edited book deals with latest comprehensive information on conventional and high throughput techniques and technologies that are recently used to study plant microbial interface for agricultural research and enhancing plant productivity. Plant microbiota are important for many plant growth promotion activity and agricultural productivity and are sustainable green technology for enhancing agricultural productivity under changing environment. The book covers recent information about the plant associated microbiota and their ecology. It discusses technologies to isolate and test microbiota inhabiting in different portion of plants. The book explores the conventional methods as well as the most recently recognized high throughput technologies which are important for productive agroecosystems to feed the growing global population. This book is of interest to teachers, researchers, microbiologist, plant and environmental scientist and those interested in environment stewardship around the world. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences and policy makers to be a useful to read.
    Type of Medium: Online Resource
    Pages: XVIII, 438 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811950292
    Series Statement: Microorganisms for Sustainability, 37
    URL: https://doi.org/10.1007/978-981-19-5029-2
    DOI: 10.1007/978-981-19-5029-2
    DDC: 579
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  • 30
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    Online Resource
    Enzymes for Pollutant Degradation (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Cytology. ; Biotechnology. ; Enzymology. ; Microbiology. ; Cell Biology. ; Biotechnology. ; Enzymology.
    Description / Table of Contents: 1 Oxidoreductases for removal of environmental pollutants -- 2 Synthesis of industrial enzymes from lignocellulosic fractions -- 3 Pleurotus-derived laccases, immobilization, and bioremediation applications -- 4 Microbial lipases for polyester degradation -- 5 Application of Microbial Biofilms in Biocatalysis and Biodegradation -- 6 Pyrethroid-degrading microorganisms and their potential application for the bioremediation of contaminated environments -- 7 Bacterial Biodegradation of Phenolic Hydrocarbons -- 8 Biosorption of Industrial wastewater by microalgae -- 9 Plastic degradation and utilization by microbes: Challenges and scope -- 10 Marine Microorganisms: From pollutant degradation to added-value products -- 11 Biodegradation of pesticides used in the agriculture by soil microorganisms -- 12 Probiotic enzymes in biodegradation and value-added products -- 13 Current state, challenges and perspectives on microbial degradation of dioxine and furan -- 14 The Management of Crude Oil Spill by Bioremediation Technique -- 15 Bacterial Pigments- an Untapped Colorful Microbial World -- 16 Bioinoculants for rapid production of vermicompost -- 17 Microbial-mediated mechanism to improve rock phosphate solubilization and its agronomic implications.
    Abstract: This book is about different Enzymes from various sources that play an important role in the degradation of an array of pollutants with simultaneous generation of value-added products. This is an “Edited Book” which deals a comprehensive knowledge on the role of different microorganisms/their enzymes in the degradation of pollutants, wastewater treatment with simultaneous production of value added products. It also deals the current state, perspectives and various challenges associated with the microbial/enzymatic degradation of environmental pollutants. This book will provide a profound knowledge on the importance of microorganisms/their enzymes in the degradation of pollutants like pesticides, antibiotics, toxic/hazardous chemicals, endocrine disrupting chemicals/compounds with production of value-added products like bioplastics for the sustainable development of society. It covers various existing wastewater treatment approaches using microorganisms alone and /or in combination of other methods with their merits, demerits and future prospects.
    Type of Medium: Online Resource
    Pages: VIII, 339 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811645747
    Series Statement: Microorganisms for Sustainability, 30
    URL: https://doi.org/10.1007/978-981-16-4574-7
    DOI: 10.1007/978-981-16-4574-7
    DDC: 579
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    Online Resource
    Microbial Products for Health, Environment and Agriculture (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Microbial ecology. ; Industrial microbiology. ; Microbial populations. ; Microbiology. ; Environmental Microbiology. ; Industrial Microbiology. ; Microbial Communities. ; Microbial Ecology.
    Description / Table of Contents: Chapter 1. The good side of evil: Harnessing the power of Helminths as therapeutics -- Chapter 2. Microbes: An integral component of flavor production -- Chapter 3. Clinical potential of bacteriophage and endolysin based therapeutics: a futuristic approach -- Chapter 4. Probiotics : Origin, products and regulations in India -- Chapter 5. Fungi and its by-products in food industry: An unexplored area -- Chapter 6. Biogenic synthesis of nanomaterials toward environment-friendly approach -- Chapter 7. Fungal potential for the degradation of synthetic dyes: An overview of renewable alternatives for the production of lignin-modifying enzymes. Advances in biotechnology -- Chapter 8. Industrial scale production of important therapeutic proteins using bacterial expression system -- Chapter 9. Role of microbes and microbial products in cancer therapeutics. Chapter 10. Bacterial cellulose: A multifaceted microbial product -- Chapter 11. Bioremediation: Going the ‘nano’ way -- Chapter 12. Recent advances in microbial remediation techniques for xenobiotics-polluted soil -- Chapter 13. Microbial Enzymes as Thrombolytics -- Chapter 14. Plant growth promoting microbes and their potential application in biotechnology -- Chapter 15. Advances in the bioremediation of pharmaceuticals and personal care products (PPCPs)- polluted water and soil -- Chapter 16. Screening of microbial enzymes and their potential applications in the bioremediation process. .
    Abstract: This edited volume discusses the role of various microbial products in healthcare, environment and agriculture. Several microbial products are directly involved in solving major health problems, agricultural and environmental issues. In healthcare sector, microbes are used as anti-tumor compounds, antibiotics, anti-parasitic agents, enzyme inhibitors and immunosuppressive agents. Microbial products are also used to degrade xenobiotic compounds and bio-surfactants, for biodegradation process. In agriculture, microbial products are used to enhance nutrient uptake, to promote plant growth, or to control plant diseases. The book presents several such applications of microbes in the ecosystems. The chapters are contributed from across the globe and contain up-to-date information. This book is of interest to teachers, researchers, microbiologists and ecologists. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences.
    Type of Medium: Online Resource
    Pages: VIII, 378 p. 56 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811619472
    Series Statement: Microorganisms for Sustainability, 31
    URL: https://doi.org/10.1007/978-981-16-1947-2
    DOI: 10.1007/978-981-16-1947-2
    DDC: 579
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    Meta-analysis in Clinical Research: Principles and Procedures (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Biologicals. ; Biopharmaceutics. ; Pharmacology. ; Preclinical Research. ; Biologics.
    Description / Table of Contents: Chapter 1_Introduction -- Chapter2_Systematic literature review (SLR) -- Chapter 3_Registration and software’s -- Chapter 4_Quality Assessment of Studies -- Chapter 5_Extraction and Analysis of data -- Chapter 6_Models in Meta-analysis -- Chapter 7_Heterogeneity and Publications bias -- Chapter 8_Sensitivity and subgroup analysis -- Chapter 9_Meta-regression -- Chapter 10_Plots in Meta-analysis -- Chapter 11_Network Meta-analysis -- Chapter 12_Common mistakes -- Chapter 13_Challenges -- Chapter 14_Future Perspectives -- Chapter 15_Future perspectives.
    Abstract: This book provides conceptual information on the various processes involved in meta-analysis. It examines the importance of meta-analysis for the analyses of clinical data to draw a valid conclusion using suitable software. The initial sections of the book introduce meta-analysis, how to perform a systematic literature review (SLR), quality assessment of studies, extraction, and analysis of data. The subsequent section of the book contains information on advanced topics including, meta-regression, network meta-analysis, issues, mistakes, and future perspectives. In summary, the book provides a statistical method for combining the results of different studies on the same topic and resolving conflicts among studies. This book is written with the intent to allow a wide range of readers including students, researchers, and health care professionals, including physicians, nurses, pharmacists, and paramedical, and is also helpful for a beginner who would like to do a meta-analysis.
    Type of Medium: Online Resource
    Pages: XXII, 119 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923700
    URL: https://doi.org/10.1007/978-981-99-2370-0
    DOI: 10.1007/978-981-99-2370-0
    DDC: 615
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    The Mesentery and Inflammation (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Medical genetics. ; Clinical health psychology. ; Human physiology. ; Pharmacology. ; Neuroscience. ; Psychiatry. ; Medical Genetics. ; Health Psychology. ; Human Physiology.
    Description / Table of Contents: Introduction -- Development, anatomy and histology of the mesentery -- The mesenteric intersitium -- Mesnteric organ lymphatics -- The mesentery as an immunological organ -- Bacterial translocation to the mesentery -- The microbiome of mesenteric lymh nodes -- Mesenteric Adenopathy and adenitis -- The effects of mesenteric inflammation on the intestine -- The mesentery as an ADME organ -- Targteing the mesentery using surgery -- Future directions.
    Abstract: The volume summarizes the most recent advances in our understanding of the mesentery and explains the how these are important in inflammation. It comprises a series of state of the art chapters by leading authorities in each area. It explains how recent advances in our understanding of the mesenteric organ, have advanced the diagnosis and treatment abdominal and systemic conditions including cancer, inflammatory bowel disease and endocrine conditions such as diabetes, and circulatory disorders such as atherosclerosis. .
    Type of Medium: Online Resource
    Pages: X, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031177743
    Series Statement: Progress in Inflammation Research, 90
    URL: https://doi.org/10.1007/978-3-031-17774-3
    DOI: 10.1007/978-3-031-17774-3
    DDC: 615
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    Prebiotics, Probiotics and Nutraceuticals (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    URL: https://doi.org/10.1007/978-981-16-8990-1
    DOI: 10.1007/978-981-16-8990-1
    DDC: 615
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    Model Organisms to Study Biological Activities and Toxicity of Nanoparticles (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Nanotechnology. ; Biology Technique. ; Pharmacology. ; Human Physiology. ; Nanotechnology. ; Experimental Organisms.
    Description / Table of Contents: Chapter 1. Nanotechnology : Application in biology and medicine -- Chapter 2. Biological activities of nanoparticles and mechanism of action -- Chapter 3. Application of nanoparticles in Drug delivery -- Chapter 4. Antimicrobial activity of metallic nanoparticles using prokaryotic model organisms -- Chapter 5. Modelling nanoparticles parameters for antibacterial activities -- Chapter 6. Saccharomyces cerevisiae as model organism to study biological activities of nanoparticles -- Chapter 7. Investigation of Biological activities of Nanoparticles using Cell Lines -- Chapter 8. Caenorhabditis elegans: a model organism to decipher biological activities of nanoparticles -- Chapter 9. Zebra fish model system to investigate biological activities of nanoparticles -- Chapter 10. Drosophila melanogaster - A model organism to understand biological activities of nanoparticles -- Chapter 11. Understanding the biological activities of nanoparticles using murine models -- Chapter 12. Insecticidal activity nanoparticles and mechanism of action -- Chapter 13. Routes of Exposures and Toxicity of Nanoparticles -- Chapter 14. Toxicological evaluation of nanoparticles using prokaryotic model organisms -- Chapter 15. Evaluation of Toxicity Nanoparticles using Cell lines -- Chapter 16. Saccharomyces cerevisiae : Model organism to evaluate nanoparticles toxicity -- Chapter 17. Caenorhabditis elegans: Evaluation of nanoparticle toxicity -- Chapter 18. Zebra fish: A laboratory model to evaluate Nanoparticle Toxicity -- Chapter 19. Evaluation of toxicity of nanoparticles using Brine Shrimp -- Chapter 20. Drosophila Model to Decipher the Toxicity of Nanoparticles -- Chapter 21. Murine models to understand the toxicity of nanoparticles -- Chapter 22. Challenges and future perspectives of Nanotoxicology.
    Abstract: This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.
    Type of Medium: Online Resource
    Pages: XIII, 466 p. 64 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811517020
    URL: https://doi.org/10.1007/978-981-15-1702-0
    DOI: 10.1007/978-981-15-1702-0
    DDC: 615
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    The 'Big Four’ Snakes of India : Venom Composition, Pharmacological Properties and Treatment of Envenomation (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Invertebrates. ; Medicine Research. ; Biology Research. ; Epidemiology. ; Biochemistry. ; Pharmacology. ; Invertebrate Zoology. ; Biomedical Research. ; Epidemiology. ; Biochemistry.
    Description / Table of Contents: Chapter 1. Introduction: The snakebite problem -- Chapter 2. Evolution of snakes and systematics of Big Four venomous snakes of India -- Chapter 3. Snake venom: Composition, evolution, function, and biomedical applications -- Chapter 4. Indian spectacled cobra (Naja naja) -- Chapter 5. Indian common Krait (Bungarus cerelus) -- Chapter 6. Indian Russell’s viper (Daboia russelii) -- Chapter 7. Indian Saw-scaled viper (Echis carinatus) -- Chapter 8. Prevention and Treatment of Big Four Snakebite in India.
    Abstract: This book provides detailed and updated knowledge about medically important ‘Big Four’ venomous snakes of India (Indian spectacled cobra, Indian common krait, Indian Russell’s viper, and Indian saw-scaled viper). This book essentially covers the snakebite problem in the world with particular reference to Asia and India. It discusses the evolution and systematics of venomous snakes, emphasizing ‘Big Four’ venomous snakes of India; the evolution and composition of venoms determined by traditional biochemical and modern proteomic analyses. It also describes the pharmacological properties of enzymatic and non-enzymatic toxins of ‘Big Four’ venomous snakes of India. Different chapters discuss exciting topics such as species-specific and geographical differences in venom composition and its impact on pathophysiology and clinical manifestations of snakebite envenomation in India, biomedical application of Indian snake venom toxins; production and quality assessment of commercial antivenom, prevention, and treatment of snakebite in India, adverse effects of antivenom including strategies to combat antivenom reactions inpatient. This book caters to toxinologists, pharmacologists, zoologists, antivenom manufacturers, biochemists, clinicians, evolutionary biologists, herpetologists, and informed non-specialists interested to know about the Indian snake venoms. .
    Type of Medium: Online Resource
    Pages: XI, 161 p. 55 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811628962
    URL: https://doi.org/10.1007/978-981-16-2896-2
    DOI: 10.1007/978-981-16-2896-2
    DDC: 615
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    Application of Microbes in Environmental and Microbial Biotechnology (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Microbial ecology. ; Food Microbiology. ; Industrial microbiology. ; Microbial populations. ; Microbiology. ; Environmental Microbiology. ; Food Microbiology. ; Industrial Microbiology. ; Microbial Communities.
    Description / Table of Contents: Chapter 1.Impact of isotropic and anisotropic plasmonic metal nanoparticles on healthcare and food-safety management -- Chapter 2. An introduction to different methods of nanoparticles synthesis -- Chapter 3. Classification, Synthesis, and Application of Nanoparticles against Infectious Diseases -- Chapter 4. Nanotechnology in Food Science -- Chapter 5. Facets of Nanotechnology in food processing, packaging and safety: an emerald insight -- Chapter 6. Nanotechnology and its potential application in postharvest technology -- Chapter 7. Nanotechnology mediated detection and control of phytopathogens -- Chapter 8. Nanosystems for Cancer Therapy -- Chapter 9. Phytoplankton mediated nanoparticles for cancer therapy. Chapter 10. Nanotechnology and its potential implications in Ovary Cancer -- Chapter 11. Nanotechnology: An Emerging Field in Protein Aggregation and Cancer Therapeutics -- Chapter 12. Bio-nano interface and its potential application in Alzheimer’s disease -- Chapter 13. Potential of curcumin nanoparticles in tuberculosis management -- Chapter 14. Application of Nanobiosensor in Health care sector -- Chapter 15. Bioactive nanoparticles: A next generation smart nanomaterials for pollution abatement and ecological sustainability -- Chapter 16. Smart nano-materials for bio-imaging applications:An overview -- Chapter 17. Biology of Earthworm in a World of Nano-materials: New Room, Challenges and, Future Perspectives -- Chapter 18. Bioethanol production from agricultural wastes with the aid of nanotechnology -- Chapter 19. Nanotechnology for sustainable bioenergy production.
    Abstract: This comprehensive edited book on microbial prospective discusses the innovative approaches and investigation strategies, as well as provides a broad spectrum of the cutting-edge research on the processing, properties and technological developments of microbial products and their applications. Microbes finds very important applications in our lives including industries and food processing. They are widely used in the fermentation of beverages, processing of dairy products, production of pharmaceuticals, chemicals, enzymes, proteins and biomaterials; conversion of biomass into fuel, fuel cell technology, health and environmental sectors. Some of these products are produced commercially, while others are potentially valuable in biotechnology. Microorganisms are considered invaluable in research as model organisms. This is a useful compilation for students and researchers in microbiology, biotechnology and chemical industries.
    Type of Medium: Online Resource
    Pages: IX, 736 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811622250
    Series Statement: Environmental and Microbial Biotechnology,
    URL: https://doi.org/10.1007/978-981-16-2225-0
    DOI: 10.1007/978-981-16-2225-0
    DDC: 579
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    Coronary Artery Disease: Therapeutics and Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    URL: https://doi.org/10.1007/978-981-15-2517-9
    DOI: 10.1007/978-981-15-2517-9
    DDC: 615
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    Approaching Complex Diseases : Network-Based Pharmacology and Systems Approach in Bio-Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    URL: https://doi.org/10.1007/978-3-030-32857-3
    DOI: 10.1007/978-3-030-32857-3
    DDC: 615
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    Microbial Genomic Islands in Adaptation and Pathogenicity (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Diseases Causes and theories of causation. ; Microbial genetics. ; Microbiology. ; Pathogenesis. ; Microbial Genetics.
    Description / Table of Contents: Chapter 1. An introduction of microbial genomic islands for evolutionary adaptation and pathogenicity -- Chapter 2. Computation tools for prediction and analysis of genomic islands -- Chapter 3. An overview of genomic islands’ main features and computational prediction: the CMNR group of bacteria as a case study -- Chapter 4. Microbial genomic island discovery, visualization and analysis -- Chapter 5. Genomic islands in bacterial genome evolution and speciation -- Chapter 6. Genomic islands in the gut microbiome: current knowledge and the application in the probiotics field -- Chapter 7. Genomic islands in nutritional fitness and adaptation -- Chapter 8. Genomic islands involved in iron uptake -- Chapter 9. Genomic islands in uropathogeneic E. coli -- Chapter 10. Genomic islands in Helicobacter species -- Chapter 11. Genomic islands in Staphylococcus -- Chapter 12. Genomic islands in Pseudomonas species -- Chapter 13. Genomic islands in Klebsiella pneumonia -- Chapter 14. Molecular Insights into Genomic Islands and Evolution of Vibrio cholerae -- Chapter 15. Genomic islands in marine bacteria -- Chapter 16. Challenges in Eventing Horizontal Gene Transfer -- chapter 17. Artificial Intelligence and machine learning for prediction and analysis of genomic islands.
    Abstract: This book elucidates the role of microbial genomic islands (GEIs) in genome stability, plasticity, evolutionary adaptation, and pathogenicity in the bacterial population. The initial chapters of the book present tools, including bioinformatics, artificial intelligence, machine learning, next-generation sequencing, and molecular biology techniques, for the analysis of the genomic islands. The book also discusses the importance of genomic islands in bacterial speciation, acquisition of genes related to resistome, nitrogen fixation, mobilomes, and nutritional fitness and adaptation. It provides recent advances in understanding microbial genomic islands' distribution, evolution, and mechanistic modes of behavior in pathogenic, non-pathogenic, and environmental species. This book is a valuable source for beginners in molecular microbiology, students, researchers, clinicians, stakeholders, and policymakers interested in understanding the role of GEIs in the adaptive evolution of microorganisms.
    Type of Medium: Online Resource
    Pages: XXIII, 356 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811993428
    URL: https://doi.org/10.1007/978-981-19-9342-8
    DOI: 10.1007/978-981-19-9342-8
    DDC: 579
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  • 41
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    Online Resource
    Data Monitoring Committees (DMCs) : Past, Present, and Future (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Description / Table of Contents: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Abstract: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Type of Medium: Online Resource
    Pages: XII, 111 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287602
    URL: https://doi.org/10.1007/978-3-031-28760-2
    DOI: 10.1007/978-3-031-28760-2
    DDC: 615
    Language: English
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  • 42
    Online Resource
    Online Resource
    Synbiotics for the Management of Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Abstract: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Type of Medium: Online Resource
    Pages: XVII, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811975509
    URL: https://doi.org/10.1007/978-981-19-7550-9
    DOI: 10.1007/978-981-19-7550-9
    DDC: 615
    Language: English
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  • 43
    Online Resource
    Online Resource
    Emerging Treatment Technologies for Waste Management (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Microbiology Technique. ; Refuse and refuse disposal. ; Environmental chemistry. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Microbiology. ; Microbiology Techniques. ; Waste Management/Waste Technology. ; Environmental Chemistry. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Chapter 1. Recent advances in physicochemical and biological approaches for degradation and detoxification of industrial wastewater -- Chapter 2. Bioremediation of Hexavalent Chromium from industrial effluents -- Chapter 3. Integration of nanotechnologies for sustainable remediation of environmental pollutants -- Chapter 4. Arsenic removal using nanotechnology -- 5. Emerging Contaminants in wastewater: Sources of contamination, toxicity, and removal approaches -- Chapter 6. Application of biochar for sustainable development in agriculture and environmental remediation -- Chapter 7. Life cycle analysis to estimate environmental impact of the food industry -- Chapter 8. Food Wastes: Perceptions, Impacts and Management -- Chapter 9. Hydrothermal Carbonization of Organic Fraction of Municipal Solid Waste: Advantage, Disadvantage and Different Application of Hydrochar -- Chapter 10. Pollutants characterization and toxicity assessment of pulp and paper industry sludge for safe environmental disposal -- Chapter 11. Use of flue gas as a carbon source for algal cultivation.
    Abstract: This book is focused on the current status of industrial pollution, its source, characteristics, and management through various advanced treatment technologies. The book covers the recycle, reuse and recovery of waste for the production of value-added products. The book explores industrial wastewater pollution and its treatment through various advanced technologies and also the source and characteristics of solid waste and its management for environmental safety. It discusses new methods and technologies to combat the waste-related pollution and focuses on the use of recycled products. This book is of value to upcoming students, researchers, scientists, industry persons and professionals in the field of environmental science and engineering, microbiology, biotechnology, toxicology, further it is useful for global and local authorities and policy makers responsible for the management of liquid and solid wastes.
    Type of Medium: Online Resource
    Pages: XIV, 257 p. 36 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811620157
    URL: https://doi.org/10.1007/978-981-16-2015-7
    DOI: 10.1007/978-981-16-2015-7
    DDC: 579
    Language: English
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  • 44
    Online Resource
    Online Resource
    Microbial Polymers : Applications and Ecological Perspectives (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Molecular biology. ; Biotechnology. ; Microbiology Technique. ; Microbiology. ; Molecular Biology. ; Biotechnology. ; Microbiology Techniques.
    Description / Table of Contents: Chapter 1. The production and applications of microbial derived polyhydroxy butyrates -- Chapter 2. Fungal exopolysaccharides: types, production and application -- Chapter 3. Isolation and purification of microbial exopolysaccharides and their industrial applications -- Chapter 4. A review on properties and application of xanthan gum -- Chapter 5. Biosynthesis and characterization of poly-(3)-hydroxyalkanoic acid by Bacillus megaterium SF4 using different carbohydrates -- Chapter 6. Mushroom mycelia-based material: an environmental friendly alternative to synthetic packaging -- Chapter 7. An overview of microbial derived polyhydroxy butyrate (PHB): production and characterization -- Chapter 8. Insight of Biopolymers and applications of Polyhydroxyalkanoates -- Chapter 9. Microbial pigments and their application -- Chapter 10. Extracellular polymeric substances from agriculturally important microorganisms -- Chapter 11. Significance of bacterial polyhydroxy alkanoates in rhizosphere -- Chapter 12. Role of microbial biofilms in agriculture: perspectives on plant and soil health -- Chapter 13. Biological soil crusts to keep soil alive, rehabilitate degraded soil, and develop soil habitats -- Chapter 14. Fungal chitosan :the importance and beneficiation of this biopolymer in industrial and agriculture process -- Chapter 15. Role of microbial extracellular polymeric substances in soil fertility -- Chapter 16. Microbes derived exopolysaccharides play role in salt stress alleviation in plants -- Chapter 17. Microbial exopolysaccharides: structure and therapeutic properties -- Chapter 18. Microbial biopolymers: pharmaceutical, medical & biotechnological applications -- Chapter 19. Mycobacterium Biofilms synthesis, ultra structure and their perspectives in drug tolerance, environment and medicine -- Chapter 20. A comprehensive review on different microbial derived pigments and their multipurpose activities -- Chapter 21. Microbial polysaccharides with potential industrial applications: diversity, synthesis and their applications -- Chapter 22. Eco friendly microbial biopolymers: recent development, biodegradation and applications -- Chapter 23. Microbial biopolymers as an alternative construction binder -- Chapter 24. Genetic engineering approaches for high end application of biopolymers:Advances and future prospects -- Chapter 25. Microbial pigments: secondary metabolites with multifaceted roles -- Chapter 26. Bio-fermentative production of xanthan gum biopolymer and its application in petroleum sector -- Chapter 27. A comparative study on biodegradable packaging materials: current status and future prospects -- Chapter 28. Environmental implications of microbial bioplastics for a sustainable future.
    Abstract: This book cover all types of microbe based polymers and their application in diverse sectors with special emphasis on agriculture. It collates latest research, methods, opinion, perspectives, and reviews dissecting the microbial origins of polymers, their production, design, and processing at industrial level, as well as improvements for specific industrial applications. Book also discusses recent advances in biopolymer production and their modification for amplifying the value. In addition, understanding of the microbial physiology and optimal conditions for polymer production are also explained. This compilation of scientific chapters on principles and practices of microbial polymers fosters the knowledge transfer among scientific communities, industries, and microbiologist and serves students, academicians, researchers for a better understanding of the nature of microbial polymers and application procedure for sustainable ecosystem.
    Type of Medium: Online Resource
    Pages: XI, 710 p. 134 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811600456
    URL: https://doi.org/10.1007/978-981-16-0045-6
    DOI: 10.1007/978-981-16-0045-6
    DDC: 579
    Language: English
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  • 45
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    Online Resource
    From Obesity to Diabetes (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Metabolism Disorders. ; Pharmacology. ; Metabolic Disease.
    Description / Table of Contents: Part I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
    Abstract: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
    Type of Medium: Online Resource
    Pages: VIII, 513 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030999957
    Series Statement: Handbook of Experimental Pharmacology, 274
    URL: https://doi.org/10.1007/978-3-030-99995-7
    DOI: 10.1007/978-3-030-99995-7
    DDC: 615
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  • 46
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    Online Resource
    Marine Biomaterials : Drug Delivery and Therapeutic Applications (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    URL: https://doi.org/10.1007/978-981-16-4787-1
    DOI: 10.1007/978-981-16-4787-1
    DDC: 615
    Language: English
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  • 47
    Online Resource
    Online Resource
    Microbes for Natural Food Additives (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Food Microbiology. ; Food Analysis. ; Chemistry. ; Microbiology. ; Food Microbiology. ; Food Chemistry.
    Description / Table of Contents: 1. Microbial Food additives: Types, Functions and challenges -- 2. Applications of enzymes in food industries as additives -- 3. Microbial antioxidants in food products -- 4. Microbial and bio-based preservatives:recent advances in antimicrobial compounds -- 5. Prebiotic and Synbiotic Foods -- 6. Microbial stablizers in food processing -- 7. Biosurfactants: promising biomolecules in the food industry -- 8. Additives in Dairy Based Food -- 9. Hypersensitivity associated with food additives.
    Abstract: This book provides all the aspects of microbes for food additives, and a detailed description of their different categories. The chapters provide a step-by-step overview of microbial food additives as enzymes, antioxidants, stabilizers, emulsifiers, organic acids, colorants, sweeteners, flavoring compounds that have been used commercially by industrialists. In addition, an emphasis on the use of microbes as therapeutic agents such as probiotics and enzymes have also been given in the respective chapters. Furthermore, the book also comprises the detailed description of legislation and policies for the use of microbial additives at large scale in different food industries. Therefore, this book provides a comprehensive, state of art updated literature which can be used by the food scientists, nutritionists, microbiologists and a health-conscious layman to check the food additive list on a product for a nutritious and safer food.
    Type of Medium: Online Resource
    Pages: X, 227 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811957116
    Series Statement: Microorganisms for Sustainability, 38
    URL: https://doi.org/10.1007/978-981-19-5711-6
    DOI: 10.1007/978-981-19-5711-6
    DDC: 579
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  • 48
    Online Resource
    Online Resource
    Nanostructures for Antimicrobial and Antibiofilm Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Nanotechnology. ; Plant biotechnology. ; Plant genetics. ; Microbial genetics. ; Plants Evolution. ; Microbiology. ; Nanotechnology. ; Plant Biotechnology. ; Plant Genetics. ; Microbial Genetics. ; Plant Evolution.
    Description / Table of Contents: Preface -- Polymer Macromolecules to Polymeric Nanostructures: Efficient antibacterial candidates -- Algal Nanoparticles -- Green and bio-mechanochemical synthesis of silver nanoparticles and their antibacterial activity -- Novel antimicrobial compounds from indigenous plants and microbes -- Antimicrobial properties of prodigionins from bacteria -- Immobilized systems based on secondary metabolites produced by microorganisms -- Nanomaterials as Therapeutic agents for antimicrobial therapy -- Antivral natural compounds -- A Review of Next-Generation Nano-Antimicrobials in orthopaedics -- Recent advances in the design and synthesis of antibacterial and biofilm nanoplatforms -- Recent nanotechnological tools for irradication of biofilms on medical devices -- Recent Trends in Antimicrobial or Biofilms with Advanced Specificity at gene level treatment -- Current and Future Prospects of Nanotechnology for the Study of Infectious Diseases -- Nanostructures for antimicrobial and antibiofilm photodynamic therapy -- Nanoparticle-based antimicrobial coating on medical implants -- Anti-quorum sensing systems and biofilm formation -- Antibiofilm, antifouling and anticorrosive biomaterials and nanomaterials for marine applications -- A review of applications and challenges of silver nanoparticles as antimicrobial agents -- Estimating the effect of ZnO nanoparticles using CS/PVA/MC3 biofilms for antimicrobial activity -- Mesoporous silica nanomaterials as antibacterial and antibiofilm agents -- Index.
    Abstract: In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.
    Type of Medium: Online Resource
    Pages: XIV, 458 p. 99 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030403379
    Series Statement: Nanotechnology in the Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-40337-9
    DOI: 10.1007/978-3-030-40337-9
    DDC: 579
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  • 49
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    Online Resource
    Bioprospecting Algae for Nanosized Materials (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Plant biotechnology. ; Nanotechnology. ; Biotechnology. ; Biology Technique. ; Bioremediation. ; Microbiology. ; Plant Biotechnology. ; Nanotechnology. ; Biotechnology. ; Biological Techniques. ; Environmental Biotechnology.
    Description / Table of Contents: SECTION I Introduction -- 1. Algal Nanotechnology: Scope and Limitations -- SECTION II Synthesis and Properties of Algal Nanomaterials -- 2. Algal Nanoparticles: Synthesis and Characterization -- 3. Biogenic Synthesis of Metallic Nanoparticles from Algae -- SECTION III Production of Nanomaterials and Nanoproducts from Algae -- 4. Microalgal Applications in Nanotechnology: An Outstanding Tool for Nanocompounds Synthesis and Bioproducts Obtention -- 5. Revalorisation of Algae Natural Resources as Starting Materials for the Development of Nanotechnology-Based Composite Materials -- 6. Seaweeds: A Potential Source in Progressing Nanotechnology -- 7. Pelagic Sargassum as Source of Quantum Dots -- SECTION IV Biomedical Applications of Algal Nanomaterials -- 8. Algal-Mediated Biosynthesis of Nanoparticles and Their Potential Therapeutic Applications -- 9. Strategies for Nanoencapsulation of Algal Proteins, Protein Hydrolysates and Bioactive Peptides: The Effect of Encapsulation Techniques on Bioactive Properties -- 10. Nanoformulations Loaded with Microalgal Bioactive Compounds for Disease Therapy -- 11. Marine Algal Products and Algal Nanoparticle Synthesis against Cancer -- 12. Surface Functionalized Diatoms for Drug Delivery and Tissue Engineering Applications -- SECTION V Industrial and Environmental Applications of Algal Nanomaterials -- 13. Algae for Nanocellulose Production -- 14. Pelagic Sargassum as a Source of Micro and Nano Cellulose for Environmentally Sustainable Plastics -- 15. Algal Nanotechnology for Wastewater Treatment -- 16. Surface Functionalized Diatom Silica as a Bio-Absorbent for the Removal of Toxins from Water -- 17. Microalgal Nanotechnology for the Remediation of Environmental Pollutants -- Index.
    Abstract: Algae are simple, primitive, heterogeneous, autotrophic, eukaryotic or prokaryotic organisms that lead a symbiotic, parasitic or free-living mode of life. Microalgae and macroalgae possess great potential in various fields of application. Microalgae are ubiquitous and extremely diverse microorganisms that can accumulate toxic contaminants and heavy metals from wastewater, making them a superior candidate to become a powerful nanofactory. Algae were discovered to reduce the presence of metal ions, and afterwards aid in the biosynthesis of nanoparticles. Since algae-mediated biogenic nanoparticles are eco-friendly, cost-effective, high-yielding, speedy and energy-efficient, a large number of studies have been published on them in the last few years. This book focuses on recent progress on the utilization of algae for the synthesis of nanoparticles, their characterization and the possible mechanisms involved. Bioprospecting Algae for Nanosized Materials describes the synthesis of algal nanomaterials and its application in various fields for sustainable development. This book outlines the procedures to prepare phyconanomaterials, techniques to utilize the nanomaterials, and applications in agriculture, environment and medicine.
    Type of Medium: Online Resource
    Pages: XIV, 447 p. 61 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030815578
    Series Statement: Nanotechnology in the Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-81557-8
    DOI: 10.1007/978-3-030-81557-8
    DDC: 579
    Language: English
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  • 50
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    Online Resource
    Pharmacogenomics in Precision Medicine : From a Perspective of Ethnic Differences (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Medical genetics. ; Pharmacology. ; Biomedical Research. ; Medical Genetics.
    Description / Table of Contents: Chapter 1. Introduction and Principles of Pharmacogenomics and Precision medicine -- Chapter 2. Pharmacogenomics in Cardiovascular Diseases -- Chapter 3. Pharmacogenomics of Antitumor Chemotherapeutic Agents -- Chapter 4. Pharmacogenomics of Antitumor Targeted Agent and Immunotherapy -- Chapter 5. Pharmacogenomics of Immunosuppressant -- Chapter 6. Pharmacogenomics of Psychiatric drugs -- Chapter 7. Pharmacogenomics of Anti-Infective Agents -- Chapter 8. Pharmacogenomics of Antithrombotic drugs -- Chapter 9. Pharmacogenomics in Therapeutic Drug Monitoring -- Chapter 10. Pharmacomicrobiomics -- Chapter 11. Genotyping technology in Pharmacogenomics -- Chapter 12. The Ethical, Legal and Regulatory Issues Associated with Pharmacogenomics -- Chapter 13. Cost-effectiveness of pharmacogenetic-guided treatment -- Chapter 14. Application of pharmacogenomics in drug discovery and development -- Chapter 15. Barriers and Solutions in Clinical Implementation of Pharmacogenomics for Personalized Precision Medicine.
    Abstract: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
    Type of Medium: Online Resource
    Pages: VIII, 289 p. 33 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811538957
    URL: https://doi.org/10.1007/978-981-15-3895-7
    DOI: 10.1007/978-981-15-3895-7
    DDC: 615
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  • 51
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    Online Resource
    Pseudomonas aeruginosa : Biology, Pathogenesis and Control Strategies (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Medical microbiology. ; Diseases Causes and theories of causation. ; Microbiology. ; Medical Microbiology. ; Pathogenesis.
    Description / Table of Contents: Part I. Biology and Evolution of Pseudomonas aeruginosa -- Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen -- Iron Homeostasis in Pseudomonas aeruginosa: Targeting Iron Acquisition and Storage as an Antimicrobial Strategy -- Controlling Biofilm Development Through Cyclic di-GMP Signaling -- Pseudomonas aeruginosa Quorum Sensing -- Antibiotic Resistance in Pseudomonas -- Part II. Cell Envelope and Secretion Systems -- Cell Envelope Stress Response in Pseudomonas aeruginosa -- Flagella, Chemotaxis and Surface Sensing -- Antimicrobial Weapons of Pseudomonas aeruginosa -- Pseudomonas aeruginosa Antivirulence Strategies: Targeting the Type III Secretion -- Part III. Pathogenesis and Virulence -- What Makes Pseudomonas aeruginosa a Pathogen? -- Transcriptional Profiling of Pseudomonas aeruginosa Infections -- Molecular Mechanisms Involved in Pseudomonas aeruginosa Bacteremia -- Pseudomonas aeruginosa in the Cystic Fibrosis Lung -- Role of Two Component System Networks in Pseudomonas aeruginosa Pathogenesis -- Mixed Populations and Co-Infection: Pseudomonas aeruginosa and Staphylococcus aureus -- How to Manage Pseudomonas aeruginosa Infections.
    Abstract: This book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen. Pseudomonas aeruginosa is responsible for one out of ten hospital infections. Additionally, this Gram-negative bacterium is accountable for persistent infections in immunocompromised individuals and the leading cause of chronic lung infections in cystic fibrosis patients. This book provides insight on the metabolic versatility of Pseudomonas aeruginosa and its mechanisms for biofilm formation that make this organism highly efficient in causing infections. The book invites the readers to learn more about the intrinsic ability of Pseudomonas aeruginosa to resist a wide variety of antimicrobial agents due to the concerted action of multidrug efflux pumps, antibiotic-degrading enzymes, and the low permeability of bacterial cellular envelopes. Particular focus is put on the evolutionary role of different types of protein-secretion systems in pathogenesis, flagella and their role in chemotaxis and surface sensing, and host-pathogen interactions. This book is a useful introduction to the field for junior scientists interested in the biology and pathogenesis of Pseudomonas aeruginosa. It is also an interesting read for advanced scientists and medical specialists working within this field, providing a broader view of the topic beyond their specific area of specialization.
    Type of Medium: Online Resource
    Pages: XVII, 445 p. 69 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084911
    Series Statement: Advances in Experimental Medicine and Biology, 1386
    URL: https://doi.org/10.1007/978-3-031-08491-1
    DOI: 10.1007/978-3-031-08491-1
    DDC: 579
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  • 52
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    Online Resource
    Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Human Physiology. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: The effect of curcumin supplementation on pulse wave velocity in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled trial -- Role of Curcumin in Regulating Long Noncoding RNA Expression in Cancer -- The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-blind, Randomized, Placebo-Controlled Trial -- Protective effects of curcumin phytosomes against high-fat diet-induced atherosclerosis -- Intravenous Curcumin Mitigates Atherosclerosis Progression in Cholesterol-fed Rabbits -- Updated review on the role of curcumin in gastrointestinal cancers -- Curcumin can bind and interact with CRP: an in silico study -- Antifungal activities of curcumin and difluorinated curcumin against clinical dermatophyte isolates -- Therapeutic Effect of Curcumin in Women with Polycystic Ovary Syndrome Receiving Metformin: A Randomized Controlled Trial -- Effect of Curcumin on Severity of Functional Dyspepsia; a Triple Blinded Clinical Trial -- Possible mechanisms and special clinical considerations of curcumin supplementation in patients with COVID-19 -- Paving the road toward exploiting the therapeutic effects of ginsenosides: an emphasis on autophagy and endoplasmic reticulum stress -- Medicinal plants and phytochemicals regulating insulin resistance and glucose homeostasis in type 2 diabetic patients: A clinical review -- Plants with anti-addictive potential -- Use of Plant-Derived Natural Products in Sleep Disturbances -- The effects of nutraceuticals and herbal medicine on Candida albicans in oral candidiasis: a comprehensive review -- Pharmacological properties of the plant-derived natural products cannabinoids and implications for cardiovascular health -- Beneficial effects of plant-derived natural products on non-alcoholic fatty liver disease -- Crocin Improves Oxidative Stress in Testicular Tissues of Streptozotocin-Induced Diabetic Rats -- Beneficial Medicinal Plants for Memory and Cognitive Functions Based on Traditional Persian Medicine -- The use of medicinal plants for the treatment of alopecia in the Canon of Avicenna: an evidence-based review -- Ethnobotanical uses, phytochemistry and pharmacology of different Rheum species (Polygonaceae): A review -- Genus Rosa: A review of ethnobotany, phytochemistry and traditional aspects according to Islamic traditional medicine (ITM) -- Ethnobotany, Phytochemistry, traditional and modern uses of Actaea racemosa L. (Black cohosh): A review -- Ethnobotany, phytochemistry and pharmacological features of Centella asiatica: a comprehensive review -- Ethnomedicinal uses, phytochemistry and pharmacology of different Cichorium species (Asteraceae): A review -- Medicinal species of the genus Berberis: A review of their traditional and ethnomedicinal uses, phytochemistry and pharmacology -- Protective effects of intravenous magnesium sulfate in stroke patients receiving amiodarone: A randomized controlled trial -- In silico identification of novel interactions for FABP5 (Fatty Acid-Binding Protein 5) with nutraceuticals: Possible repurposing approach.
    Abstract: Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal of this contributed volume is to present a comprehensive collection on most important therapeutic aspects of plant-derived natural products and their molecular mechanisms of action.
    Type of Medium: Online Resource
    Pages: X, 603 p. 814 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030648725
    Series Statement: Advances in Experimental Medicine and Biology, 1308
    URL: https://doi.org/10.1007/978-3-030-64872-5
    DOI: 10.1007/978-3-030-64872-5
    DDC: 615
    Language: English
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    Marine Biomaterials : Therapeutic Potential (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Therapeutics. ; Pharmaceutical chemistry. ; Biomaterials. ; Pharmacology. ; Translational Research. ; Therapeutics. ; Pharmaceutics. ; Biomaterials.
    Description / Table of Contents: Chapter 1. Marine biomaterials: resources, categories and applications -- Chapter 2. Cross-linked marine biopolymers for delivery of therapeutics -- Chapter 3. Chitosan and Chitooligosaccharides: Preparation, Characteristics and their Potential Application as Therapeutic Agents -- Chapter 4. Marine collagen for delivery of therapeutics -- Chapter 5. Marine Biopolymers for delivery of Gene -- Chapter 6. Hydrogel scaffolds based on alginate, gelatin, and 2-hydroxyethyl methacrylate for tissue regeneration -- Chapter 7. Tissue Engineering application of marine based materials -- Chapter 8. Marine biopolymer for theranostic applications -- Chapter 9. Marine biomaterials as carrier of drugs/biomolecules for management of bone disorders -- Chapter 10. Expanding Role of Marine Natural Compounds in Immunomodulation: Challenges and Future Perspectives -- Chapter 11. Marine origin Bioactive Peptides: novel advances in the therapeutic potential.
    Abstract: This book provides updated information on marine-based biomedical carriers and their therapeutic potential. Marine biomaterials and bio-based carriers show wide application in pharmaceutical and biomedical fields to deliver small and large molecules. Biomaterial-based composites, scaffolds, or matrix systems are sound systems for controlled and prolonged drug release in target sites and control the premature release of drugs or bioactive compounds. This book discusses essential topics such as the therapeutic potential of marine collagen, management of bone disorders, gene delivery, natural marine compounds in immunomodulation, theranostic applications, tissue engineering, and regeneration. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. Marine biomaterial-based systems are popular for tissue engineering and biomedical imaging. This book is ideal for industry experts, students, and researchers in pharmaceutical sciences and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 392 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811653742
    URL: https://doi.org/10.1007/978-981-16-5374-2
    DOI: 10.1007/978-981-16-5374-2
    DDC: 615
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    Online Resource
    Cannabis/Marijuana for Healthcare (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medical care. ; Therapeutics. ; Neurology . ; Medicine Research. ; Biology Research. ; Pharmacology. ; Health Care. ; Therapeutics. ; Neurology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. A Complete Patent Analysis of Cannabis/Marijuana in Drug Delivery and Disease Conditions -- Chapter 2. Neuropharmacological Approaches to Modulate Cannabinoid Neurotransmission -- Chapter 3. Cannabinoids in Cancer: Cross-talk Between Cannabinoids and miRNAs -- Chapter 4. Cannabis As A Potent Therapeutic Agent For Pharmaceutical Drugs: Recent Advancement In Drug Discovery And Human Healthcare -- Chapter 5. Cannabinoid-Based Innovative Prophylactic and Therapeutic Interventions for Neuropathic Pain and Migraine -- Chapter 6. The Legality of Use and Consumption of Cannabis (Marijuana) in the United States of America -- Chapter 7. Cannabis in Healthcare: Ethnobotanical and Pharmaceutical Perspectives and Legal Status in Turkey and The Middle East -- Chapter 8. Understanding the Pharmacokinetics, Safety Profile, and Scope of the Concerned Issue to Evade the Consumption of Cannabis/Marijuana -- Chapter 9. Traditional Uses of Cannabis in The Middle East and The Pathway to Cannabis-Based Healthcare in Israel -- Chapter 10. Traditional and Modern Health Uses of Cannabis sativa L. in Africa and its Phytochemical and Pharmacological Profile -- Chapter 11. Traditional Claims on Cannabis: An Indian and Global Scenario -- Chapter 12. Cannabis (Bhanga) in Classical Text of Ayurveda: An Evidence-Based Rationale -- Chapter 13. Cannabis-Based Cosmetic Products and Their Uses -- Chapter 14. Cannabis as A Unique and Valuable Nutraceutical Formulation for the Current and Future Global Wellbeing -- Chapter 15. Traditional, Cultural, and Nutraceutical Aspects of Cannabis in India.
    Abstract: The book contains review articles providing a comprehensive overview of cannabis/marijuana’s diverse healing aspects in human healthcare (medicinal, nutraceutical, skincare, etc.). The research articles include the role of cannabis in cancer treatment, drug discovery, cosmeceutical potential, prophylactic and therapeutic use for treating neuropathic pain and migraine, pharmacokinetics, safety profile, and issues related to the consumption of cannabis/marijuana.Another salient feature of the book is a complete mapping and region- and sector-wise critical analysis of cannabis/marijuana patents on healthcare and future directions for the benefit of researchers and businesses/entrepreneurs interested in the rapidly advancing area of cannabis. The text describes cannabis/marijuana’s detailed legal aspects, production prospects, and applications for healthcare and recreational purposes in the USA. It traces the traditional roots of cannabis use in Turkey, Israel, the Middle East, Africa, and India. This unique compendium of articles will be useful as a reference book for students, researchers, academics, business houses, and all individuals interested in medicinal, nutraceutical, cosmeceutical, traditional, legal, and commercial aspects of cannabis usage.
    Type of Medium: Online Resource
    Pages: XIX, 319 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811688225
    URL: https://doi.org/10.1007/978-981-16-8822-5
    DOI: 10.1007/978-981-16-8822-5
    DDC: 615
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    Technological Advancement in Algal Biofuels Production (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biology Technique. ; Biotechnology. ; Microbiology. ; Biological Techniques. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Biotechnological approaches to enhance algae biofuel production -- Chapter 2. The use of omics technologies, random mutagenesis, and genetic transformation techniques to improve algae for biodiesel industry -- Chapter 3. Algal butanol production: recent developments -- Chapter 4. Algal synthesis of gold nanoparticles: applications in bioenergy -- Chapter 5. Challenges assessment in economic Algal biofuel Production -- Chapter 6. Influence of culture conditions on the microalgae biomass and lipid accumulation -- Chapter 7. Advanced genetic approaches towards custom design microalgae for fourth-generation biofuels -- Chapter 8. Algal biofuel production from municipal waste waters -- Chapter 9. Positive influence and future perspective of marine alga on biofuel production -- Chapter 10. Algae bacterial mixed culture for waste to wealth conversation: a case study.
    Abstract: This edited book presents all feasible approaches to improve technology of algal biofuels production at both qualitative and quantitative front. The book’s focus in on enhancing mass scale production of algae based biofuels by addressing technological issues and filling the existing gaps to make it smooth for practical as well as commercial implementation. The book also explores in depth analysis of various issues other than technology and related to improve technological significance for practical biofuels production from algae. Low cost strategies and higher mass production is one of the most sounding agenda of the book. The book also evaluates enlighten various sustainable algal biofuels options which are close towards commercial application along with their green future prospect. Societal and environment friendly approach even for commercial application has also been discussed in book. This is a useful reading material for researchers and students of biofuels and reneable energy. .
    Type of Medium: Online Resource
    Pages: XI, 295 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811968068
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-19-6806-8
    DOI: 10.1007/978-981-19-6806-8
    DDC: 579
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    Vibrio spp. Infections (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Diseases Causes and theories of causation. ; Microbial ecology. ; Bacteria. ; Epidemiology. ; Microbiology. ; Pathogenesis. ; Environmental Microbiology. ; Bacteria. ; Epidemiology.
    Description / Table of Contents: Chapter 1. Vibrio Infections and the Twenty-First Century -- Chapter 2. New Insights into Vibrio Cholerae Biofilms from Molecular Biophysics to Microbial Ecology -- Chapter 3. Type VI Secretion Systems: Environmental and Intra-Host Competition of Vibrio cholerae -- Chapter 4. Motility Control as a Possible Link Between Quorum Sensing to Surface Attachment in Vibrio Species -- Chapter 5. The Vibrio Polar Flagellum: Structure and Regulation -- Chapter 6. Environmental Reservoirs of Pathogenic Vibrio Spp. and Their Role in Disease: The List Keeps Expanding -- Chapter 7. Cholera Dynamics and the Emergence of Pandemic Vibrio cholerae -- Chapter 8. Role of Bacteriophages in the Evolution of Pathogenic Vibrios and Lessons for Phage Therapy -- Chapter 9. Vibrio vulnificus, an Underestimated Zoonotic Pathogen -- Chapter 10. The Role of Nutrients and Nutritional Signals in the Pathogenesis of Vibrio cholerae -- Chapter 11. Stress Responses in Pathogenic Vibrios and Their Role in Host and Environmental Survival -- Chapter 12. Vibrio parahaemolyticus Epidemiology and Pathogenesis: Novel Insights on an Emerging Foodborne Pathogen -- Chapter 13. The Viable but Non-Culturable (VBNC) State in Vibrio Species: Why Studying the VBNC State Now, Is More Exciting than Ever -- Chapter 14. Structural Insights into Regulation of Vibrio Virulence Gene Networks -- Chapter 15. When Vibrios Take Flight: A Meta-Analysis of Pathogenic Vibrio Species in Wild and Domestic Birds -- Chapter 16. What Whole Genome Sequencing Has Told Us About Pathogenic Vibrios.
    Abstract: This book addresses current topics on pathogenic Vibrio spp. from a comprehensive and holistic perspective. Here, experts in the field provide timely chapters, ranging from genomics, pathogen emergence, and epidemiology to pathogenesis, virulence regulation and host colonization. Questions addressed include: How does climate change affect the spread of these bacteria? What is the status of current vaccines? Are there novel therapeutic options to treat Vibrio infections? Is there likelihood of emergence of new pathogenic strains or species? Can insights from mathematical models and epidemiology lead to prediction of pathogen outbreaks? Recent decades have seen a steady increase in Vibrio spp. infections originating in aquatic and marine habitats, driven by higher human population densities, warming of polluted oceans, natural and human-made disasters, and mass seafood production. These conditions increase the likelihood of pathogenic Vibrio spp. coming into contact with humans, making their study even more timely and relevant as these problems escalate over time. This book is a valuable resource for health management professionals, experienced microbiologists/ microbial ecologists, and early career scientists alike who want to learn more about these important environmental human pathogens. The ideas and technologies presented in this book for preventing, controlling, and monitoring Vibrio spp. infections contribute to the UN Sustainable Development Goal 3: Good Health and Well-Being. .
    Type of Medium: Online Resource
    Pages: XI, 352 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031229978
    Series Statement: Advances in Experimental Medicine and Biology, 1404
    URL: https://doi.org/10.1007/978-3-031-22997-8
    DOI: 10.1007/978-3-031-22997-8
    DDC: 579
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    Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Medical microbiology. ; Biology Technique. ; Diseases. ; Microbiology. ; Medical Microbiology. ; Experimental Organisms. ; Diseases.
    Description / Table of Contents: Chapter 1. Microbial infections and virulence factors -- Chapter 2. Microbial Pathogenesis: Virus pathogen-host interactions -- Chapter 3. A physical insight of biofilms -- Chapter 4. A Review on Microbial Pathogenesis and Host Response -- Chapter 5. Role of quorum sensing in microbial infections and biofilm formation -- Chapter 6. Microbial Pathogenesis and Antimicrobial Drug Resistance -- Chapter 7. Pathogenesis and antibiotic resistance of Staphylococcus aureus -- Chapter 8. Pathogenesis, Virulence factors and Antibiotic resistance of Group B Streptococcus -- Chapter 9. Enterococcal infections and Drug resistance mechanisms -- Chapter 10. Pathogenic Escherichia coli: Virulence factors and their Antimicrobial resistance -- Chapter 11. Enterobacter Infections and antimicrobial drug resistance -- Chapter 12. Klebsiella pneumoniae infections and antimicrobial drug resistance -- Chapter 13. Pathogenesis and drug resistance of Pseudomonas aeruginosa -- Chapter 14. Acinetobacter baumannii: Infections and drug resistance -- Chapter 15. Vibrio cholera: Mechanisms of Pathogenicity and Antibiotic resistance -- Chapter 16. Current trends in Mycobacterium tuberculosis pathogenesis and drug resistance -- Chapter 17. PATHOGENESIS OF FUNGAL INFECTIONS AND DRUG- RESISTANCE PHENOMENON -- Chapter 18. Pathogenesis and drug resistance profile of food-borne pathogens -- Chapter 19. Cell lines as in vitro model for studying microbial pathogenesis -- Chapter 20. Animal models to understand host-pathogen interactions -- Chapter 21. Caenorhabditis elegans as pathogenesis model to understand bacterial virulence -- Chapter 22. Zebra fish infection model: From pathogenesis to therapeutics -- Chapter 23. Mycobacterium pathogenesis and drug discovery: Looking through the zebra fish keyhole -- Chapter 24. Murine models to study acute and chronic bacterial infections -- Chapter 25. Non-human primate model use in understanding infectious diseases -- Chapter 26. Understanding Biofilm Dynamics: In Vitro and In Vivo Models -- Chapter 27. Model organisms and antimicrobial drug discovery -- Chapter 28. Yeast: A model organism for antimicrobial drug discovery -- Chapter 29. Caenorhabditis elegans: A tool for antimicrobial drug discovery -- Chapter 30. Zebrafish Model System in Antimicrobial Drug Discovery -- Chapter 31. Murine Models for Development of Anti-Infective Therapeutics -- Chapter 32. Non-human primate models for antimicrobial drug discovery.
    Abstract: This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
    Type of Medium: Online Resource
    Pages: XVII, 684 p. 91 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811516955
    URL: https://doi.org/10.1007/978-981-15-1695-5
    DOI: 10.1007/978-981-15-1695-5
    DDC: 579
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    Drug Target Selection and Validation (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drugs Design. ; Medicinal chemistry. ; Molecular biology. ; Pharmacology. ; Pharmaceutics. ; Structure-Based Drug Design. ; Medicinal Chemistry. ; Molecular Biology.
    Description / Table of Contents: Drug discovery paradigms: target-based drug discovery -- Drug discovery paradigms: phenotypic-based drug discovery -- Target Identification Approaches in Drug Discovery -- Introduction to target validation -- Structure-based binding pocket detection and druggability assessment -- Network-Based Target Identification -- The Current State of Precision Medicine and Targeted-Cancer Therapies – Where are We? -- Metabolic Control Analysis for drug target selection against human diseases -- Progress on open chemoinformatic tools for drug discovery.
    Abstract: The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation. It revises current classical paradigms in target and phenotypic-based drug design with still ingrained approximations and concepts and discusses the research in the new network approach concept that include kinetic selectivity and metabolic analysis. Many often-overlooked approximations and concepts in drug discovery are fully covered. Drug Target Selection and Validation includes both introductory sections and research-based sections to be of use to both students and research scientists in drug discovery, design, kinetics and metabolic analysis. Pharmaceutical scientists, pharmaceutics, drug developers, pharmacologists, biomedical researchers in computer science, medicinal chemists, and precision medicine developers benefit from the information provided. The book concludes with a chapter on chemical and structural databases.
    Type of Medium: Online Resource
    Pages: XV, 257 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030958954
    Series Statement: Computer-Aided Drug Discovery and Design, 1
    URL: https://doi.org/10.1007/978-3-030-95895-4
    DOI: 10.1007/978-3-030-95895-4
    DDC: 615
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    Mycotoxins and Mycotoxicoses (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Fungi. ; Mycology. ; Toxicology. ; Food Microbiology. ; Microbial genetics. ; Medical microbiology. ; Microbiology. ; Fungi. ; Toxicology. ; Food Microbiology. ; Microbial Genetics. ; Medical Microbiology.
    Description / Table of Contents: Chapter 1: Historical Aspect -- Chapter 2: Overview -- Chapter 3: Traditional Mycotoxins and Their Health Implications -- Chapter 4: Emerging/Lesser Known Mycotoxins and Their Clinicopathological Effects -- Chapter 5: Mushroom toxins and health hazards associated with them -- Chapter 6: Mycotoxins Co-occurrence Poisoning -- Chapter 7: Masked and New Mycotoxins -- Chapter 8: Extraction, characterization and analysis of Mycotoxins -- Chapter 9: Management Strategies -- Chapter 10: Mycotoxicokinetics and mycotoxicodynamics.
    Abstract: This book presents a comprehensive view on mycotoxins of agricultural as well as non-agricultural environments and their health effects in humans and animals. Mycotoxins have immunosuppressive effects; but some of them can cause cancers, mutagenicity, neurotoxicity, liver and kidney damage, birth defects, DNA damage and respiratory disorders. The problem of mycotoxins is long-lasting and their direct or indirect exposures to humans and animals must be further discussed. The first chapter will cover the historical perspective of mycotoxins along with timeline while the second one will provide overview including classification of mycotoxins and mycotoxicoses. The comprehensive information/ literature on traditional, emerging and mushroom mycotoxins will be given in chapters 3, 4 and 5 respectively. Chapter 6 will deal with mycotoxins co-occurrence poisoning whereas new and masked mycotoxins will be described in chapter 7. The important aspects of mycotoxin studies like extraction, characterization and analysis and management strategies will be summarized in 8 and 9 chapters. The last chapter of the book will cover the recent developments in toxicokinetic studies of mycotoxins. The book will have the most up-to-date information and recent discoveries to deliver accurate data and to illustrate essential points to a wide range of readers including mycologists, clinicians, agricultural scientists, chemists, veterinarians, environmentalists and food scientists.
    Type of Medium: Online Resource
    Pages: XXIII, 182 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811923708
    URL: https://doi.org/10.1007/978-981-19-2370-8
    DOI: 10.1007/978-981-19-2370-8
    DDC: 579
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    Microbiome-Gut-Brain Axis : Implications on Health (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Food Microbiology. ; Microbial populations. ; Bacteria. ; Microbiology. ; Food Microbiology. ; Microbial Communities. ; Bacteria.
    Description / Table of Contents: Chapter 1. Gut Microbes – Influencers of human brain -- Chapter 2. Current Insights on the Inflection of Gut Microbiome and Its Effect on Human Health -- Chapter 3. Trust your gut: The human gut microbiome in health and disease -- Chapter 4. Virome and Microbiome Interaction and Their Implication in the Human Gut Health -- 5. Interactions of Microbiome for Gut-Brain Axis Health -- Chapter 6. Diet- Gut microbiota - Brain axis and IgE mediated food allergy -- Chapter 7. Gut microbiome composition as key the factor for immunomodulation in host -- Chapter 8. Gut-Brain Axis: Role of gut microbiome on human health -- Chapter 9. Functional Role of Prebiotics Supplement in Brain Signalling -- Chapter 10. Probiotics Mechanism to Modulate Gut-Brain Axis (GBA) -- Chapter 11. Gut-brain axis: probiotic interactions and Implications for Human Mental health -- Chapter 12. Probiotic: A Sustainable Approach Towards Healthy Food -- Chapter 13. Production and biofunctionalities of milk derived bioactive peptide -- Chapter 14. Role of Probiotics in Allergic Diseases -- Chapter 15. Probiotics suppress the depression: A look at the possible mechanisms of action -- Chapter 16. The Role of Probiotics in Diabetes Control -- Chapter 17. Autism: The Role of Probiotics in gut-brain axis -- Chapter 18. From Probiotics to Postbiotics: Key to Microbiome and Health -- Chapter 19. Effect of Probiotics on Gut microbiota and brain interactions and in context of neurodegenerative and neurodevelopmental disorders -- Chapter 20. Impact of probiotics in modulation of gut microbiome -- Chapter 21. Potential of Probiotics in improving gut health -- Chapter 22. Probiotic and prebiotic interactions and their role in maintaining host immunity.
    Abstract: The book highlights the importance of prebiotics, probiotics and synbiotics in the signalling mechanism between gut microbiota and brain, also referred to as the gut-brain axis. A stable gut microbiota is essential for normal gut physiology and overall health, since it assists in proper signalling along the brain–gut axis. The book describes how the cross talks between gut microbiota and brain, not only regulate gastro-intestinal functions but also ensure proper functioning of cognitive behaviour and immunological functions. The various chapters describe probiotic microorganisms that colonize gastrointestinal tract and provide an array of health benefits to the host. It further elaborates about certain non-digestible oligosaccharides (prebiotics) are easily fermented by specialist microbes in the gut, to produce health-promoting metabolites and inhibit the growth of pathogenic bacteria. This book is useful for students, researchers and scientists in the field of microbiology, food science and nutrition. It is also meant for industry experts involved in developing nutraceuticals.
    Type of Medium: Online Resource
    Pages: XI, 443 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811616266
    URL: https://doi.org/10.1007/978-981-16-1626-6
    DOI: 10.1007/978-981-16-1626-6
    DDC: 579
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    New and Future Development in Biopesticide Research: Biotechnological Exploration (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Pharmacology. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Microbiology. ; Pharmacology. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Biopesticides in sustainable agriculture: current status and future prospects -- Chapter 2. Entomopathogenic Fungi: Current Status and Prospects -- Chapter 3. Utilization of Entomopathogenic Bacteria for modern insect pest management -- Chapter 4. Entomopathogenic Nematodes (EPNs): A Green Strategy for Management of Insect-Pests of Crops -- Chapter 5. Trends in neem (Azadirachta indica)-based botanical pesticides -- Chapter 6. Role of Plant Essential Oils in Pest Management -- Chapter 7. Plant Secondary Metabolites: Emerging Trends in Agricultural Pests Control -- Chapter 8. Transgenic plants and its role in insect control -- Chapter 9. Improving Insect Control Using Genetically Modified Entomopathogens -- Chapter 10. Importance of metabolic enzymes and their role in insecticide resistance -- Chapter 11. Insect microbiota and host immunity: An emerging target for pest control.-Chapter 12. Eco-smart Biorational Approaches in Housefly Musca domestica L. 1758 Management.
    Abstract: This book discusses different approaches for successful pest-management through biotechnological interventions. Pest management is directly associated with the agricultural productivity. The book introduces the reader to various kinds of biopesticides that have been developed and are being developed for field application. Chemical pesticides have been widely used to control pests, and these induce pesticide resistance as well as other environmental problems. This book discusses the necessity to develop alternate pest control strategies, especially environment-friendly and target-specific biopesticides against destructive pests. The book describes important aspects such as microbial biopesticides, plant-based biopesticides, natural products that act against pests and the various other biotechnological advances and limitations of these biopesticides. It provides an in-depth knowledge of the latest research and development in the area of biopesticides. This informative book is meant for students and researchers in the fields of biotechnology, agriculture and applied microbiology.
    Type of Medium: Online Resource
    Pages: VIII, 303 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811639890
    URL: https://doi.org/10.1007/978-981-16-3989-0
    DOI: 10.1007/978-981-16-3989-0
    DDC: 579
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    Nanotechnology for Advances in Medical Microbiology (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biotechnology. ; Food science. ; Microbiology Technique. ; Microbiology. ; Biotechnology. ; Food Science. ; Microbiology Techniques.
    Description / Table of Contents: 1 Green synthesized nanoparticles as a promising strategy for controlling microbial biofilm -- 2 Visual health nanocomposites: present and future -- 3 Applications of Nanomaterials in Biomedical Engineering -- 4 Nanofibers in Medical Microbiology -- 5 Extraction of silver nanoparticles (Ag-NPs) by green synthesis from aqueous extract of seaweeds and their consequences on Hela cell line and their utility on soil by spectroscopic tools -- 6 Epidemiology of COVID- 19; Special emphasis on Nanoscience and it’s implications -- 7 Surface-modified noble metal nanoparticles as antimicrobial agents: biochemical, molecular and therapeutic perspectives -- 8 Nanomaterials for Advanced Microbiology -- 9 Nanoparticles for Biofilm Control -- 10 Significance of nanoscience in food microbiology: current trend and future prospects -- 11 Nanotechnology in Microbiology -- 12 Holistic approaches for enhanced production of Prodigiosin- a natural biocolour -- 13 Applications of Nanomaterials for Water Disinfection -- 14 The Evolving Role of Nanoparticles in Bacteria Mediated Cancer Therapy -- 15 Recent progress on nano-structured materials for biomedical applications -- 16 Nanotechnology-A New Frontier in Medical Microbiology -- 17 Chitosan nanoparticles: An overview on preparation, characterization and biomedical applications. .
    Abstract: Combined fields of Microbiology and Nanotechnology have been most successful in providing novel solutions for protecting the health of humans and environment. This book covers the implications of nano-strategies to combat bacterial pathogens, applications of nanotechniques in microbiology, and innovative advances in the area of medical microbiology. Contents are divided into three sections -- Nanoscience in controlling bacterial pathogens, Nanoscience in Microbiology, Medical Microbiology. This volume is going to provide timely information about the technological advances of Nanoscience in the domain of Microbiology, with a special emphasis on Pathobiology. The book is a useful read for students and researchers in microbiology, nanotechnology and medical microbiology.
    Type of Medium: Online Resource
    Pages: XVI, 427 p. 89 illus., 78 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811599163
    Series Statement: Environmental and Microbial Biotechnology,
    URL: https://doi.org/10.1007/978-981-15-9916-3
    DOI: 10.1007/978-981-15-9916-3
    DDC: 579
    Language: English
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    Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical genetics. ; Human physiology. ; Pharmacology. ; Medical Genetics. ; Human Physiology.
    Description / Table of Contents: Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.
    Abstract: The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
    Type of Medium: Online Resource
    Pages: XII, 316 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031384370
    Series Statement: Handbook of Experimental Pharmacology, 279
    URL: https://doi.org/10.1007/978-3-031-38437-0
    DOI: 10.1007/978-3-031-38437-0
    DDC: 615
    Language: English
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  • 64
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    Online Resource
    From PharmD to Industry : A Fellowship Guide (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Description / Table of Contents: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Abstract: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Type of Medium: Online Resource
    Pages: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031357879
    Series Statement: SpringerBriefs in Pharmaceutical Science & Drug Development,
    URL: https://doi.org/10.1007/978-3-031-35787-9
    DOI: 10.1007/978-3-031-35787-9
    DDC: 615
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    Online Resource
    Bacteriocins (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Toxicology. ; Food science. ; Biotechnology. ; Microbiology. ; Toxicology. ; Food Science. ; Chemical Bioengineering.
    Description / Table of Contents: Chapter 1 Biosynthesis, structure and function of bacteriocin -- Chapter 2 Antibacterial mechanism of bacteriocin in lactic acid bacteria -- Chapter 3 Characteristics of lantibiotics -- Chapter 4 Genetic modification of bacteriocins -- Chapter 5 Potential use of bacteriocins as antibacterial agents -- Chapter 6 Application of bacteriocin in food industry -- Chapter 7 Application of bacteriocin in livesock and poultry -- Chapter 8 Bacteriocins of plant-related bacteria and biocontrol of plant pathogens -- Chapter 9 Cytotoxicity of bacteriocins to eukaryotic cells -- Chapter 10 Bacteriocins and human nutrition and health.
    Abstract: This book intends to report the new results of the study of bacteriocins, from basic research to application fields. It mainly introduces the biological characteristics of bacteriocins, the relationship between their structure and function, the antibacterial mode of action, and their application as antibacterial agents in food industry, medical care, and other areas, especially their application potential in human health. This book can be used as a reference book for researchers, undergraduates, and graduated students in the professional fields of food science and engineering, bioengineering, medicine, and agriculture.
    Type of Medium: Online Resource
    Pages: XI, 219 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819926619
    URL: https://doi.org/10.1007/978-981-99-2661-9
    DOI: 10.1007/978-981-99-2661-9
    DDC: 579
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    Pediatric Pharmacotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    URL: https://doi.org/10.1007/978-3-030-50494-6
    DOI: 10.1007/978-3-030-50494-6
    DDC: 615
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    Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    URL: https://doi.org/10.1007/978-3-030-68510-2
    DOI: 10.1007/978-3-030-68510-2
    DDC: 615
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    Substance Use Disorders : From Etiology to Treatment (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacology.
    Description / Table of Contents: 1. Methods for Population Research on Substance Use and Consequences -- 2. Translational Molecular Approaches in Substance Abuse Research -- 3. Small Molecule Neuropeptide-S and Melanocortin Receptor Ligands As Potential Treatments for Substance Use Disorders -- 4. Emerging Insights into Mu Opioid Pharmacology -- 5. Behavioral Pharmacology of Drugs Acting at Mu Opioid Receptors -- 6. The Rise and Fall of Kappa-Opioid Receptors in Drug Abuse Research -- 7. Clinical Trials for Opioid Use Disorder -- 8. Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms -- 9. Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder -- 10. Molecular Mechanisms of Amphetamines -- 11. Clinical Trials for Stimulant Use Disorders: Addressing Heterogeneities That May Undermine Treatment Outcomes -- 12. Molecular Mechanism and Cannabinoid Pharmacology -- 13. Pharmacotherapies for Cannabis Use Disorders: Clinical Challenges and Promising Therapeutic Agents -- 14. Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence -- 15. Randomized Clinical Trials Investigating Innovative Interventions for Smoking Cessation in the Last Decade -- 16. Adolescent Vulnerability to Alcohol Use Disorder: Neurophysiological Mechanisms from Preclinical Studies -- 17. Medication Development for Alcohol Use Disorder: A Focus on Clinical Studies -- 18. Newly Emerging Drugs of Abuse.
    Abstract: The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use disorders. The first section is dedicated to methodology including population-based surveys, basic neuroanatomy, chemistry, molecular biology, behavioral models and brain imaging. The second section utilizes this methodology in research related to opioids, cocaine, marijuana, alcohol and nicotine. The book is aimed at both professionals (academics, clinicians, practitioners) and students or trainees.
    Type of Medium: Online Resource
    Pages: X, 502 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030336790
    Series Statement: Handbook of Experimental Pharmacology, 258
    URL: https://doi.org/10.1007/978-3-030-33679-0
    DOI: 10.1007/978-3-030-33679-0
    DDC: 615
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    The Pharmacology of Taste (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacology.
    Abstract: The Pharmacology of Taste is comprised of contributions by leading scientists from the field of chemosensory research, presented all together in the context of pharmacological principles of receptor function. The chapters cover all levels of scientific inquiry, from molecular and physiological mechanisms underlying taste signaling to its manifestation in overt behavior. The overarching objective of this volume is to inspire the application of concepts and methods of pharmacology to the study of the chemosenses.
    Type of Medium: Online Resource
    Pages: XII, 351 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031064500
    Series Statement: Handbook of Experimental Pharmacology, 275
    URL: https://doi.org/10.1007/978-3-031-06450-0
    DOI: 10.1007/978-3-031-06450-0
    DDC: 615
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    Allergic Diseases – From Basic Mechanisms to Comprehensive Management and Prevention (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Allergy. ; Pharmacology. ; Allergology.
    Description / Table of Contents: Preface -- Part I: History and Epidemiology -- Part II: General Mechanisms -- Part III: Symptoms and Diseases -- Part IV: From Environmental Trigger to Disease Management -- Part V: Specific Mechanisms -- Part VI: Risk Factors -- Part VII: Diagnostics -- Part VIII: Allergy Prevention.
    Abstract: Allergy is the most frequent chronic disease in the 21st century having severe negative effects on health and the economy. The challenge we therefore face in medicine and science incorporates all areas of society – from politics to food industry, from schools to city planning, and many more. This volume informs the reader about continuously ongoing developments in allergy research and their implications for society. The chapter sections cover the immunological mechanisms in allergy on a molecular level, describe the triggers and cures for allergy in detail, entail clinical translation of lab findings on allergens, evaluate diagnostics for allergy markers, and provide solutions for future medical intervention or preventive strategies. Laboratory research, bioinformatics, climate modelling, patient treatment, intervention studies, epigenetics and multiple other disciplines are able to shed new light on this revolutionary field of healthcare.
    Type of Medium: Online Resource
    Pages: XI, 500 p. 70 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030840488
    Series Statement: Handbook of Experimental Pharmacology, 268
    URL: https://doi.org/10.1007/978-3-030-84048-8
    DOI: 10.1007/978-3-030-84048-8
    DDC: 615
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    Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: Part 1: Quality by Design (QbD) -- Chapter 1. Pharmaceutical Quality by Design (QbD) overview and major elements -- Chapter 2. Fundamentals of design of experiments and optimization: designs for factor screening and data analysis in pre-response surface methodology -- Chapter 3. Fundamentals of design of experiments and optimization: experimental designs in response surface methodology -- Chapter 4. Fundamentals of design of experiments and optimization: data modeling in response surface methodology -- Chapter 5. Quality by Design in pharmaceutical product and process development -- Chapter 6. A Quality by Design update on nano-drug delivery systems -- Chapter 7. Control strategies of solid dosage forms by PAT tools -- Part 2: Analytical Quality by Design (AQbD) -- Chapter 8. Analytical Quality by Design Fundamentals, Compendial and Regulatory Perspectives -- Chapter 9. Analytical Target Profile (ATP) and Method Operable Design Region (MODR) -- Chapter 10: Quality by Design applications to development of analytical methods for quality control of pharmaceuticals -- Chapter 11. Design of Experiments Applied to the Extraction of Active Compounds. .
    Abstract: Written by twenty-five authors from academia, pharmaceutical industry and Pharmacopeias worldwide, this monograph covers the fundamentals and applications of Quality by Design (QbD) and Analytical Quality by Design (AQbD) in a practical and didactic manner. The book starts by describing the motivation and the urgent need for the implementation of the QbD framework in pharmaceutical development, along with the definition of its major elements: Quality Target Product Profile (QTTP), Critical Quality Attributes (CQAs), Critical Process Parameters (CPPs), Critical Material Attributes (CMAs) and the importance of using multivariate methods of Design of Experiments (DOE). The concept of life cycle and regulatory perspectives are discussed. Three chapters are entirely dedicated to DOE theory from screening to optimization designs. Moreover, a comprehensive discussion on modelling and data treatment is presented. Practical aspects of QbD and DOE for pharmaceutical product and process of different dosage forms is included, as well as a practical guide of the input process variables, material attributes, intermediate, and final quality attributes for the most representative pharmaceutical processes. Analytical Quality by Design (AQbD) is also deeply explored, including risk analysis, definitions of Analytical Target Profile (ATP), Method Operable Design Region (MODR) and the life cycle approach, taking into account the compendial and regulatory perspectives. A detailed example of a new chromatographic method for the quality control of a pharmaceutical topical product based on the AQbD procedure is shown. Finally, advanced statistical approaches and DOE methods for extraction studies of bioactive compounds are also presented. The vast amount of information offered in this book provides a comprehensive perspective on QbD, AQbD and DOE principles, essential tools for modern pharmaceutical and analytical development.
    Type of Medium: Online Resource
    Pages: X, 266 p. 62 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315053
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 10
    URL: https://doi.org/10.1007/978-3-031-31505-3
    DOI: 10.1007/978-3-031-31505-3
    DDC: 615
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    Parkinsonism and the Environment (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Pharmacology. ; Neuroscience.
    Description / Table of Contents: Experimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson’s Disease: current state of affairs?” -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism.
    Abstract: “The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”.
    Type of Medium: Online Resource
    Pages: V, 158 p. 14 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874513
    Series Statement: Molecular and Integrative Toxicology,
    URL: https://doi.org/10.1007/978-3-030-87451-3
    DOI: 10.1007/978-3-030-87451-3
    DDC: 615
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    Bioenergy Research: Commercial Opportunities & Challenges (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Renewable energy sources. ; Microbiology. ; Renewable Energy.
    Description / Table of Contents: Chapter 1.Bioenergy Production: Opportunities for Microorganisms (Part I) -- Chapter 2. Bioenergy Production: Opportunities for Microorganisms (Part II) -- Chapter 3. Value Added Products From Agriculture, Paper And Food Waste: A Source Of Bioenergy Production -- Chapter 4. Advancements in Diatom Algae based Biofuels -- Chapter 5. Valorization of Cellulosic and SAP based Baby Diaper Waste into Functional Products: Analyses and Bioenergy Potential -- Chapter 6. Role of Operational Parameters to Enhance Biofuel Production -- Chapter 7. Advances In Bioethanol Production: Processess And Technologies -- Chapter 8. Sustainable routes for renewable energy carriers in modern energy systems -- Chapter 9. Microalgae based biofuel- integrated biorefinery approach as sustainable feedstock for resolving energy crisis. Chapter 10. Substrate characterization in the anaerobic digestion process.
    Abstract: This volume is third part of the five-part set on bioenergy research. This book provides insights into commercial advantages of commonly running bioenergy options. It explores various opportunities present at technical scale to produce biofuels. Moreover, the additional practical feasibility of the commercialization of existing biofuels including existing challenges and sustainable solutions to overcome from these technical hurdles. This Volume also focuses on the durability and long run sustainability on the new arrival of biofuels options which can be a suitable and easy replacement of currently available biofuels at pilot scale. Other four volumes of this set explore basic concepts, latest progress, bio-waste to energy conversion and integrated solution for bioenergy concerns. .
    Type of Medium: Online Resource
    Pages: XII, 317 p. 59 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811611902
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-16-1190-2
    DOI: 10.1007/978-981-16-1190-2
    DDC: 579
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    NanoBioenergy: Application and Sustainability Assessment (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Bioenergetics. ; Nanotechnology. ; Microbiology. ; Bioenergetics. ; Impact of Nanotechnology.
    Description / Table of Contents: Chapter 1. Application of nanomaterials for renewable energy production -- Chapter 2. APPLICATIONS OF NANOMATERIALS IN LIQUID BIOFUELS PRODUCTION -- Chapter 3. APPLICATIONS OF NANOMATERIALS IN GASEOUS BIOFUELS PRODUCTION -- Chapter 4. MICROBIAL ASSISTED SYNTHESIS OF NANOPHOTOCATALYSTS FOR DARK FERMENTATIVE HYDROGEN GENERATION -- Chapter 5. Green Route Synthesized Iron Nanoparticles for Biohydrogen Production -- Chapter 6. Synthesis and application of nanoengineered cellulosic biomass in biohydrogen production -- Chapter 7. Microbial mediated synthesis of Nanoparticles and their role in Bioethanol Production -- Chapter 8. Green synthesis of nanomaterials from Biomass waste for Biodiesel Production -- Chapter 9. Recent Advances in Conversion of Agricultural Waste to Biofuel by Nanoparticles.
    Abstract: This contributed volume presents new insight into sustainable possibilities of combination of nanomaterial and bioenergy production together. Biofuels as renewable energy sources have tremendous potential to replace fossil fuels in future energy scenario as biofuels production is likely to be advanced and novel research areas offers green alternative energy sources. continuous efforts are being made for the cost-effective production of biofuels worldwide to balance its techno-economy. In series of tremendous effort to improve biofuels production technologies, use of nanomaterials to improve biofuels production efficiency is highly emerging area with full scope to developed low cost, rapid technologies for biofuels production. The book covers the practical utility based properties of nanomaterial and bioenergy production together. It also discusses the recent advancements on various nanomaterial utility in biofuel production process along with its low cost application. It covers mega audiences, which include academician, researchers, and industries people. This book will be highly interesting for researchers and scientists as well as related industries.
    Type of Medium: Online Resource
    Pages: XIII, 234 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811962349
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-19-6234-9
    DOI: 10.1007/978-981-19-6234-9
    DDC: 579
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    Sustainable and Clean Energy Production Technologies (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Renewable energy sources. ; Microbiology. ; Renewable Energy.
    Description / Table of Contents: Chapter 1. Tiny Renewable Engines: Microalgae and Cyanobacteria as biofuel providers -- Chapter 2. Different Energy Management Strategies for Clean Energy -- Chapter 3. Recycle of Plastic Waste to Liquid Fuel: A sustainable energy production -- Chapter 4. Nanomaterials for Energy Storage Applications -- Chapter 5. Biomass Energy Conversion using Thermochemical and Biochemical Technologies -- Chapter 6. Pyrolysis of waste biomass using solar energy for Clean Energy Production -- Chapter 7. Biomass Digestion for Production of Electrical Energy -- Chapter 8. Solar Energy Conversion Techniques and Practical Approaches to Design Solar PV Power Station -- Chapter 9. Recent Advancement in Preparation Strategy of Efficient Graphene-Cds Based Photocatalysts for H2 Production by Water Splitting -- Chapter 10. Design and Storage of Solar Thermal Energy Production -- Chapter 11. Clean Energy using Hydroelectric generation from Rivers -- Chapter 12. Clean Energy Production using Solar Energy Resources.
    Abstract: This edited book is a comprehensive collection of chapters on various clean energy technology such as solar energy, waste biomass as energy, hydro-electricity generation, biodiesel production from biomass and strategies to cater the demand of clean renewable energy. Clean energy technologies also enhance economic growth by increasing the supply of energy demand and tackling environmental challenges and their impacts due to the use of other conventional sources of energy. The conventional/non-conventional energy production methods are efficient but it has adverse effects on environment and human health. As environmental concerns are not avoidable therefore the necessity of clean energy production comes in to the picture. The clean energy can be produced by different wastes which are caused for the environmental pollution. This book covers various aspects of new and renewable clean energy production technology and its utilization in different fields. This is a useful reading material for students and researchers involved in clean energy study.
    Type of Medium: Online Resource
    Pages: VII, 288 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811691355
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-16-9135-5
    DOI: 10.1007/978-981-16-9135-5
    DDC: 579
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    Micro-algae: Next-generation Feedstock for Biorefineries : Contemporary Technologies and Future Outlook (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biochemical engineering. ; Industrial microbiology. ; Biotechnology. ; Microbiology. ; Bioprocess Engineering. ; Industrial Microbiology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Third-generation biofuels from Microalgal Bioresource: Potential strategy and current trends -- Chapter 2. The promising future of microalgae as biofuels and valuable bioproducts. Chapter 3. Overview on advanced microalgae-based sustainable biofuel generation and its life cycle assessment . Chapter 4. Microalgae Cell Wall Disruption and Biocomponents Fractionation for Fuel Conversion. -Chapter 5. Recent advances in hydrothermal liquefaction of microalgae -- Chapter 6. Carotenoids and pigments generation using the microalgal production system. Chapter 7. Molecular engineering/metabolic engineering based advanced biotechnological approach in microalgal biorefinery -- Chapter 8.Algae-bacteria interactomics unveils their role in growth and production of high-value biorenewables -- Chapter 9.Microalgae and Cyanobacteria: A potential source for drug discovery using genome mining approach -- Chapter 10.Synthetic biology-based advanced biotechnological approach in microalgal biorefinery.
    Abstract: The edited book covers all potential products from microalgal-based biorefinery having the focus on contemporary technologies and future outlook. Along with the focus on microalgal biorefinery products, the book also focuses on biotechnological advances via the utilization of modern molecular biology, system biology, synthetic biology, or metabolic engineering approach in microalgal biorefinery. The development of any technologies has a direct effect on the human being and the environment, therefore, the socio-economic, techno-economic, and environmental impact of the microalgae-based biorefineries will also be included in the book. In microalgal biomass-based biorefinery different biofuel- biodiesel, bioethanol, bio-hydrogen, and value-added compounds such as carotenoids, fatty acids, and protein can be produced simultaneously. Understanding the technical advances to develop an integrated biorefinery approach with the motive of designing a consolidated self-sustainable microalga-based biorefinery. This book is equally beneficial for researchers and engineers in biomass-based biorefineries or the bachelors, master, or young budding graduate students as a textbook. .
    Type of Medium: Online Resource
    Pages: XVI, 230 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811906800
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-19-0680-0
    DOI: 10.1007/978-981-19-0680-0
    DDC: 579
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    Winning Grants (2023)
    Cham :Springer Nature Switzerland :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: Preface -- Abbreviations -- Chapter 1 – Why you need this book and why I wrote it -- Chapter 2 – What you need to do before you write a grant -- Chapter 3 – The idea -- Chapter 4 – Go solo or collaborate? -- Chapter 5 – What the entrepreneur needs to know -- Chapter 6 – The grant package -- Chapter 7 – The main event – writing it -- Chapter 8 – Edit / Polish / Shine / Repeat -- Chapter 9 – Are you ready to submit it? -- Chapter 10 - Post submission steps to win the grant -- Afterthoughts -- Index -- About the Author.
    Abstract: As an academic or a small business owner, you will need to write grants at some point in your career. Writing them though is not enough, what you also need to know is how to win grants. Much has been written about writing grants, the mysterious special ability called ‘grantsmanship’, so it occurred to me that there is a need to come at this differently and spill the beans. The difficulty in getting a grant, in particular an NIH grant like an R01 in the USA is often described, it is competitive and gets tougher every year. Your proposal therefore must stand out, it must connect with the reviewers. This is true for all types of grants, give the reviewer what they want always. But also, you need to connect to the program officer, the committee that ultimately makes funding decisions and you must take care of a myriad of other details outside of the main event which is describing the “science”. This means you cannot rely on just out-writing the competition, it is more than that as you have to out-think, out-strategize and out-schmooze them. If you have been continually funded for decades that is terrific, but if you want to keep being funded there is no guarantee what got you there will keep you there. What was a hot technology 4-5 years ago is not the new thing anymore, you will need to do something different, but what? You therefore need to not only think about writing great grants, you need to put it into practice and win them. Having written and won grants from the NIH and DOD over the past 17 years (and longer by the time you read this) I possess a valuable perspective. Each grant and study section will be different. Whether a big or small grant it does not seem to make a difference the reviewers will critique your efforts, they may not like it, they may reject your ideas or they may love it. You have some small degree of control until the proposal leaves your hands or more correctly you click ‘submit’. You will need to differentiate your grant from the hundreds of others in many ways, but you cannot change who you are, your history so how you describe yourself and team will also have an impact. You could spend hundreds of hours on your proposal or just a day and the outcome might still be the same. This small book is a summary of my own personal experiences and will provide some advice that will help you learn how to do a better job of winning grants. This book is written by a scientist who writes the grants and develops commercial products; Provides a unique perspective on what you need to write better grants; Teaches you how to continually win grants; This book provides examples from the authors own grant applications; The reader will be inspired to start a company to win small business grants.
    Type of Medium: Online Resource
    Pages: XIX, 106 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031275166
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 17
    URL: https://doi.org/10.1007/978-3-031-27516-6
    DOI: 10.1007/978-3-031-27516-6
    DDC: 615
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    Probiotics, Prebiotics, Synbiotics, and Postbiotics : Human Microbiome and Human Health (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biology. ; Molecular biology. ; Microbial ecology. ; Microbiology. ; Biological Sciences. ; Molecular Biology. ; Microbial Ecology.
    Description / Table of Contents: Part I: Current State of Knowledge regarding the Human Microbiome Structure, Function, and Diversity -- Chapter 1. Impact of Dietary Habits, Ethnicity and Geographical Provenance in Shaping Human Gut Microbiome -- Chapter 2. Methods Used for Studying Human Microbiome -- Chapter 3. Factors Affecting Composition of the Human Microbiome -- Part II: Correlation of the Human Microbiome to Specific Health/Disease Conditions -- Chapter 4. Mapping the Microbial Metabolites in Metabolic Disorders -- Chapter 5. Human Microbiome in Malnutrition -- Chapter 6. Human Microbiome and the Immune System Functioning -- Chapter 7. Human Microbiome and the Susceptibility to Infections -- Chapter 8. Human microbiome and the neurological disorders -- Chapter 9. Exploring the Unexplored Arena: Butyrate As a Dual Communicator in the Gut-Brain Axis -- Chapter 10. Human Microbiome and Lifestyle Disorders -- Chapter 11. Correlation of Human Microbiome and Immune Functioning to Covid-19 Infections: An Overview -- Chapter 12. Exploring the Pathoprofiles of SARS-COV-2-infected Human Gut-Lungs Microbiome Crosstalks -- Chapter 13. Role of Human Microbiome in Cardiovascular Disease: Therapeutic Potential and Challenges -- Chapter 14. The Human Microbiome and Respiratory Diseases -- Part-III: Manipulation of the Human Microbiome for Better Health -- Chapter 15. Probiotics: An Emerging Strategy for Oral Health Care -- Chapter 16. Dietary Modulation of Nervous and Immune System: Role of Prebiotics/ Synbiotics/ Postbiotics -- Chapter 17. Probiotics for Skin Health -- Chapter 18. Human Microbiome and Autism-Spectrum Disorders -- Chapter 19. Psychobiotics as an Emerging Category of Probiotic Products -- Chapter 20. Probiotics for Vaginal Health -- Chapter 21. Interactions between Microbial Therapeutics and the Endogenous Microbiome -- Part IV: Applied and Translational Aspects -- Chapter 22. The Role of a Multi-Spore Probiotic in the Management of Metabolic Endotoxemia - A Major Driver of Chronic Illness -- Chapter 23. Characterization and Authentication of Probiotic Preparations -- Chapter 24. A Survey of Commercially Available Probiotics and Prebiotics -- Chapter 25. Regulatory Aspects Relevant to Probiotic Products -- Chapter 26. Probiotic Identity from Spore – Focus on Bacillus Probiotics.
    Abstract: This book explains the potential value of microbiome and microbiome composition associated with human health and diseases. The opening chapters describe the current state of knowledge regarding the human microbiome structure, function, and diversity. The mechanisms of action and the various putative uses of human microbiome are then examined specific to healthy and disease conditions. Readers will find detailed information on its manipulation of human microbiome studies as well as its applied and translational aspects in the current field. The latest knowledge on probiotics, prebiotics, synbiotics, and postbiotics is presented, and specific cases to date are discussed. This book features knowledge from leading researchers working on different aspects of the human microbiome and its manipulation for better health. Overall, this book is an excellent source for microbiome researchers and students from all levels seeking the most up-to-date advancements in the field and also to point toward the future directions.
    Type of Medium: Online Resource
    Pages: XV, 588 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819914630
    URL: https://doi.org/10.1007/978-981-99-1463-0
    DOI: 10.1007/978-981-99-1463-0
    DDC: 579
    Language: English
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    Fungi and Fungal Products in Human Welfare and Biotechnology (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Fungi. ; Mycology. ; Biotechnology. ; Microbiology. ; Fungi. ; Biotechnology.
    Description / Table of Contents: Part I. Plant Growth Promotion and Sustainability -- Chapter 1. Arbuscular mycorrhizal fungi: role as biofertilizers, technology development and economics -- Chapter 2. Role of ectomycorrhizal fungi in human welfare -- Chapter 3. Fungal ministrations in soil detoxification, building and health restoration -- Chapter 4. Emerging mucormycosis: problems and treatments -- Chapter 5. Microplastic pollution: sources, environmental hazards and mycoremediation as a sustainable solution -- Part II. Fungal metabolic Products -- Chapter 6. A bird’s eye view of fungal peptides -- Chapter 7. Cultivation, bioactive metabolites and application of caterpillar mushroom Cordyceps militaris: Current status, issues and perspectives -- Chapter 8. Lactic acid production from fungal machineries and mechanism of PLA synthesis: Application of AI based technology for improved productivity -- Chapter 9. Discovery of bioactive metabolites from the genus Arthrinium -- Chapter Chapter 10. Wide range applications of fungal pigments in textile dyeing -- Part III. Fungi in Food Biotechnology -- Chapter Chapter 11. The potential of mushrooms in developing healthy food and biotech products -- Chapter 12. Fungal enzyme-based nutraceutical oligosaccharides -- Chapter 13. Applications of fungi for alternative protein -- Part IV. Fungal Enzymes and Other Biotech Products -- Chapter 14. Fungal enzymes in the production of biofuels -- Chapter 15. Fungal pectinases: Diversity and multifarious applications -- Chapter 16. Applicability of fungal xylanases in food biotechnology -- Chapter 17. Fungal therapeutic enzymes: Utility in the treatment of human ailments -- Chapter 18. Heterologous gene expression in Pichia pastoris: Success stories and commercial ventures -- Chapter 19. Agro-industrial residues: an ecofriendly and inexpensive substrate for fungi in the development of white biotechnology -- Chapter 20. Design strategies for mycelium-based composites -- Chapter 21. Development of building insulation material from fr fungal mycelium.
    Abstract: This book presents various biotechnological applications of the fungal systems in pharmaceuticals, nutraceuticals, textile industry, bioremediation, biofuel, and the production of biomolecules. It discusses the important role of fungal secondary metabolites in human welfare and nutrition. It explores fungi as the vital sources of novel substances with antidiabetic, antibiotic as well as prebiotic properties. The book further describes the natural and unique ability of fungi to biodegrade macro- and microplastics by using them as a source of carbon and energy. Notably, it presents the properties and applications of bioactive fungal polysaccharides and discusses the latest developments in utilizing these biopolymers in human nutrition. In addition, the book examines the production of biodegradable and sustainable natural colorants from fungal sources. This book is a valuable source for mycologists, biotechnologists, and microbiologists for understanding the important role of fungi in biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 678 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811988530
    URL: https://doi.org/10.1007/978-981-19-8853-0
    DOI: 10.1007/978-981-19-8853-0
    DDC: 579
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    Biomedical Applications and Toxicity of Nanomaterials (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Abstract: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Type of Medium: Online Resource
    Pages: XVIII, 768 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978340
    URL: https://doi.org/10.1007/978-981-19-7834-0
    DOI: 10.1007/978-981-19-7834-0
    DDC: 615
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    Brief Lessons in Microbiology : From the Origin of Life to Artificial Intelligence (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Virology. ; Medical microbiology. ; Biofilms. ; Microbiology. ; Virology. ; Medical Microbiology. ; Biofilms.
    Description / Table of Contents: Chapter 1: The world of microorganisms -- Chapter 2: The dawn of microbiology -- Chapter 3: Communication between microorganisms -- Chapter 4: Microbial communities -- Chapter 5: Gene transfer -- Chapter 6: Multidrug resistant bacteria -- Chapter 7: Synthetic biology in microbiology -- Chapter 8: Artificial intelligence in microbiology -- Chapter 9: Emerging and zoonotic diseases -- Chapter 10: COVID-19 -- Chapter 11: Future pandemics -- Chapter 12: Into a brighter future.
    Abstract: Recent discoveries in microbiology are hard to grasp for those unfamiliar with scientific jargon, and the research data can be overwhelming even for those working in other scientific fields. This book aims to remedy this situation by presenting the most interesting findings and current trends in microbiology in an easy-to-read and understandable format. The first part tells the story of the beginnings of microbiology itself and introduces the reader to the founders of this fascinating research discipline. The second part focuses on communication between microorganisms and how they organize themselves into fascinating microbial cities called “biofilms”. The reader also learns how bacteria exchange genetic material - mechanisms that are the root of the emergence of multidrug-resistant superbugs, pathogens that pose a major burden to human health and our healthcare systems. The third part is devoted to the latest techniques being used by scientists to study, control, and manipulate microorganisms for our benefit. The final part links the first three parts together and highlights how infectious diseases, including coronaviruses, can be transmitted from animals to humans, how global warming is affecting emerging diseases, and provides information on the actions that need to be taken to get ahead of pathogenic microbes and future pandemics. This comprehensive, state-of-the-art book is intended for anyone interested in microbiology and epidemiology, from biology and biomedical students in schools and colleges, to patients suffering from infectious diseases who want to learn more about their condition. The concepts covered in this book contribute to UN Sustainable Development Goal 3: Health and Well-Being.
    Type of Medium: Online Resource
    Pages: XV, 160 p. 23 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031295447
    URL: https://doi.org/10.1007/978-3-031-29544-7
    DOI: 10.1007/978-3-031-29544-7
    DDC: 579
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    Endolysosomal Voltage-Dependent Cation Channels (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Physiology. ; Cytology. ; Life sciences. ; Pharmacology. ; Physiology. ; Cell Biology. ; Life Sciences.
    Description / Table of Contents: Part I: Physiological Functions of Endo-lysosomal Cation Channels -- NAADP-Mediated Ca2+ Signalling -- NAADP-Dependent TPC Current -- NAADP-Evoked Ca2+ Signaling: The DUOX2–HN1L/JPT2–Ryanodine Receptor 1 Axis -- TPC Functions in the Immune System -- Lysosomal Ion Channels and Lysosome– 1 Organelle Interactions -- TRPML1 and TFEB, an Intimate Affair -- Lysosomal Potassium Channels -- Part II Structure and Composition of TPC and TRPML Channels -- Structure and Function of Plant and Mammalian TPC Channels -- A Structural Overview of TRPML1 and the TRPML Family -- Endo-Lysosomal Two-Pore Channels and Their Protein Partners -- Part III: Tools and Methods to Characterize Endolysosomal Cation Channels -- Electrophysiological Techniques on the Study of Endolysosomal Ion Channels -- The Plant Vacuole as Heterologous System to Characterize the Functional Properties of TPC Channels -- Expanding the Toolbox: Novel Modulators of Endolysosomal Cation Channels -- Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging.
    Abstract: This book covers the molecular structures and the cellular and in vivo function of endosomes and lysosomes, i.e. intracellular vesicles which are involved in many cellular processes such as endocytosis, intracellular trafficking, degradation of material from inside (e.g. autophagy) and outside the cell as well as exocytosis. Membranes of endolysosomal organelles contain an amazing number and diversity of ion channels. These ion channels are the topic of the present book that focusses on describing the structure, the biophysical properties, physiological functions of endolysosomal ion channels at the molecular, cellular and in vivo level. .
    Type of Medium: Online Resource
    Pages: X, 304 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315237
    Series Statement: Handbook of Experimental Pharmacology, 278
    URL: https://doi.org/10.1007/978-3-031-31523-7
    DOI: 10.1007/978-3-031-31523-7
    DDC: 615
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    Mushrooms with Therapeutic Potentials : Recent Advances in Research and Development (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Therapeutics. ; Internal medicine. ; Fungi. ; Mycology. ; Microbiology. ; Medical microbiology. ; Pharmacology. ; Therapeutics. ; Internal Medicine. ; Fungi. ; Medical Microbiology.
    Description / Table of Contents: Chapter 1. Mushrooms as Promising Therapeutic Resources: Review and Future Perspectives -- Chapter 2. Medicinal Mushrooms for Respiratory Health -- Chapter 3. Therapeutic and Prophylactic Potential of Medicinal Mushrooms in COVID-19 -- Chapter 4. Influences of Edible Mushrooms on Dynamic and Diversity of Gut Microbiota -- Chapter 5. Mushrooms – From Traditional Remedies to the Modern Therapeutics -- Chapter 6. Biopharmaceutical Potential of Ophiocordyceps sinensis for Human Health -- Chapter 7. Anticancer Potential of Ganoderma lucidum and İts Relevant Modes of Action -- Chapter 8. Cognitive Enhancing Effects of Medicinal Mushrooms: A Potential Neuroprotective Implication in Dementias -- Chapter 9. Potential of Medicinal Mushrooms in Human Health and Welfare: An Overview -- Chapter 10. Mycotherapeutics Reduce Nephrotoxicity and Renal Diseases -- Chapter 11. Proteomic Research on the Therapeutic Properties of Medicinal Mushrooms -- Chapter 12. Cordyceps militaris (L.): Medicinal aspects in terms of ethnobotanical and pharmacological perspectives -- Chapter 13. Mycotherapeutics Affecting Dopaminergic Neurotransmission to Exert Neuroprotection -- Chapter 14. Biological Activities of Some Edible Mushrooms -- Chapter 15. Nephroprotective Effects of Four Ganoderma Species -- Chapter 16. Mechanisms Involved in Edible Mushrooms' Health Beneficial Effects -- Chapter 17. Mycotherapy (Medicinal Mushrooms) as a Potential Treatment for Epilepsy -- Chapter 18. Natural vs. Synthetic Psilocybin: The Same or Completely Different? -- Chapter 19. Preventative and Curative Properties of Reishi and Maitake Mushrooms in Cancer.
    Abstract: The book presents new and novel perceptions about ailments alleviating the effects of several mushroom species. Also, the book highlights the curative role of medicinal mushrooms on some peripheral and central diseases. Various chapters in the book (primarily reviews) have been dedicated to providing the therapeutic efficacy of mushrooms against respiratory illnesses, gut microbiota, COVID-19, dementia, epilepsy, mental ailments, cancers, cardiovascular, kidney-related diseases, and other common pathologies. Thus, medicinal mushrooms are current and future consumable healthcare products that usually exhibit nourishing properties and possess prophylactic and therapeutic values with minimal adverse effects and contraindications. The book focuses on Sustainable Development Goal (SDG 3) to promote healthy lives and well-being for all. Medical, pharmacy, nursing, and CAM (complementary and alternative medicine) students, practitioners, scholars, researchers, other healthcare professionals, and general readers are this book’s potential audience. The book can be adopted as a textbook for undergraduate and graduate courses so that the therapeutic potential of mushrooms can reach a wider audience. This book strives to create a new resource for the future use of medicinal mushrooms in various disorders. .
    Type of Medium: Online Resource
    Pages: XX, 509 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995507
    URL: https://doi.org/10.1007/978-981-19-9550-7
    DOI: 10.1007/978-981-19-9550-7
    DDC: 615
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    Recent Technologies for Waste to Clean Energy and its Utilization (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Microbiology. ; Refuse and refuse disposal. ; Environment. ; Microbiology. ; Waste Management/Waste Technology. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1. Biomass Energy Utilization, Conversion Technologies -- Chapter 2. Biohydrogen Production Using Microbial Electrolysis Cell -- Chapter 3. Biohydrogen Production Using Microbial Electrolysis Cell -- Chapter 4. Microbial Waste Biomass as A Resource of Renewable Energy -- Chapter 5. Vanadium Redox Flow Batteries for Large Scale Energy Storage -- Chapter 6. Biomass Fast Pyrolysis Simulation: A Thermodynamic Equilibrium Approach -- Chapter 7. Potential of waste cooking oil for emphasizing on biodiesel: Put waste to Green Energy -- Chapter 8. Low Cost Biomass Adsorbents for Arsenic Removal from Wastewater -- Chapter 9. Biodiesel Production from Algal Biomass -- Chapter 10. Valorisation of Agricultural and Food Waste Biomass for Production of Bioenergy -- Chapter 11. Biomass Conversion: Production of oxygenated fuel additives -- Chapter 12. Application of microbial based adsorbent for removal of heavy metal from aqueous solution. .
    Abstract: This book refers to the various biomass valorisation in various fields like bio-fuel; biodiesel; hydrogen production; energy application, environmental pollution using recent clean technologies. Clean energy technology refers to any process, product or service that reduces negative environmental impacts through significant energy efficiency improvements, sustainable use of resources or environmental protection activities. It covers all aspects of new and renewable clean energy production technology. The concept of eco-efficiency involves both ecological and economic aspects of sustainable agriculture. This book is of interest to teachers, researchers, scientists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences.
    Type of Medium: Online Resource
    Pages: IX, 264 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811937842
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-19-3784-2
    DOI: 10.1007/978-981-19-3784-2
    DDC: 579
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    Polymeric Micelles: Principles, Perspectives and Practices (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery.
    Description / Table of Contents: 1. Synthesis, self-assembly and functional chemistry of Amphiphilic block copolymers -- 2. Advances in polymer optimisation for enhanced drug delivery -- 3. Dynamics of Micelle Formation -- 4. Types of Polymeric Micelles for Controlled Drug Release -- 5. Drug Solubilization and Drug Release from Polymeric Micelles -- 6. Physical and Analytical Techniques used for the Characterization of Polymeric Micelles -- 7.Stimuli-sensitive polymeric micelles for biomedical applications -- 8.Nucleic acid-based micellar therapy for the treatment of different diseases -- 9. Polymeric micelles in the delivery of therapeutic phytoconstituents -- 10. Diagnostic applications of surface-engineered polymeric micelles -- 11. Ligand conjugated polymeric micelles for targeted delivery of drug payloads in cancer therapy -- 12. Polymeric Micelles in the Delivery of Proteins -- 13. Regulatory aspects for polymeric micelles -- 14. Toxicological and regulatory challenges in design and development of polymeric micelles -- 15. Stability of polymeric micelles and their regulatory status.
    Abstract: This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.
    Type of Medium: Online Resource
    Pages: XV, 294 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903610
    URL: https://doi.org/10.1007/978-981-99-0361-0
    DOI: 10.1007/978-981-99-0361-0
    DDC: 615
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    Sustainable Agrobiology : Design and Development of Microbial Consortia (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Agricultural biotechnology. ; Microbial populations. ; Microbiology. ; Agricultural Biotechnology. ; Microbial Communities.
    Description / Table of Contents: 1. An Overall Insight into the Attributes, Interactions, and Future Applications of ‘Microbial-Consortium’ for Plant Growth Promotion, with Contemporary Approaches -- 2. Beneficial Microbial Mixtures for Efficient Biocontrol of Plant Diseases: Impediments and Success -- 3. Rhizobacterial Mediated Interactions for Enhanced Symbiotic Performance of the Root Nodule Rhizobia in Legumes -- 4. Plant Growth Promoting Bacterial Consortia Render Biological Control of Plant Pathogens: A Review -- 5. Phytohormonal Role of Microorganisms Involved in Bioinoculants -- 6. The Bacterial-Fungal Consortia: Farmer's Needs, Legal and Scientific Opportunities, and Constraints -- 7. Sustainable Improvement of Productivity and Quality of Agricultural Crops Using a Microbial Consortium -- 8. Consortia of Probiotic Bacteria and their Potentials for Sustainable Rice Production -- 9. Strategies to Evaluate Microbial Consortia for Mitigating Abiotic Stress in Plants -- 10. Co-inoculation of Rhizobacteria in Common Bean (Phaseolus vulgaris) Production in East Africa -- 11. Management of Sustainable Vegetable Production Using Microbial Consortium -- 12. Consort Interactions of the Root Endophytes Serendipita spp. (Sebacinales, Agaricomycetes, Basidiomycota) with Crop Plants -- 13. Applications of Microbial Consortia and Microbiome Interactions for Augmenting Sustainable Agrobiology -- 14. Effect of Microbial Consortium Vs. Perfected Chemical Fertilizers for Sustainable Crop Growth -- 15. Bioencapsulation of Biocontrol Agents as a Management Strategy for Plant Pathogens -- 16. Designing Tailored Bioinoculants for Sustainable Agrobiology in Multi-stressed Environments -- 17. Development and Application of Consortia Based Microbial Bioinoculants for Sustainable Agriculture.
    Abstract: This edited volume covers all aspects of microbes in consortia; their roles in the ecological balance of soil by mineralize soil nutrients, plant growth promotion, protecting plants from disease by acting as biocontrol agents etc. Step-by-step descriptions are provided to the development and designing strategies of microbial consortia of rhizobacteria, phytohormone producing with biocontrol; ACC-deaminase producing with siderophore producing; vice-versa, and many combinations of multifaceted bacteria. The development of microbial consortia into successful bioinoculant and biofertilizers is also included in various chapters. In addition, molecular mechanisms to study the synergistic behaviors of rhizobacteria, accompanied by numerous helpful schematic drawings. Using phylogeny to justify the molecular similarity among two different bacteria identifies the possibility of microbial synergism, fruitful to development of microbial consortium and establish them in the rhizosphere with consorted mechanisms. In addition, clear drawings are included in support of understanding the natural phenomenon of synergism in below-ground ecosystem. Essential information is provided on ecological management by consorted mechanisms of rhizobacteria that directly affect ‘agriculture sustainability’ and an individual chapter is devoted to the understanding of future research, and addressing bottlenecks and successful steps. This book assists the academicians, researchers and NGOs in negotiating the steep learning curve involved in gaining the skills needed to perform design and development of microbial consortiums, preparation of PGPR-based fertilizers, which offers significant advantages in terms of pertaining novel knowledge on the groundbreaking research, still ongoing.
    Type of Medium: Online Resource
    Pages: XVI, 405 p. 32 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995705
    Series Statement: Microorganisms for Sustainability, 43
    URL: https://doi.org/10.1007/978-981-19-9570-5
    DOI: 10.1007/978-981-19-9570-5
    DDC: 579
    Language: English
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    Immunity Boosting Medicinal Plants of the Western Himalayas (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Description / Table of Contents: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Abstract: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Type of Medium: Online Resource
    Pages: XIX, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995019
    URL: https://doi.org/10.1007/978-981-19-9501-9
    DOI: 10.1007/978-981-19-9501-9
    DDC: 615
    Language: English
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    Environmental Microbiology (2023)
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Details
    Keywords: Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Microbial ecology. ; Microbiology. ; Environmental Engineering/Biotechnology. ; Biotechnology. ; Microbial Ecology.
    Description / Table of Contents: Global Environment. Climate and microorganisms -- Microorganisms, actors in the environment -- Relationship between microbial energy production and material cycles -- Carbon cycle -- Environmental chemicals -- Microbial degradation of pollutants -- The microbial nitrogen cycle -- Cycles of sulfur, iron and manganese -- Heavy metals and other toxic inorganic ions -- Microorganisms at different sites: living conditions and adaptation strategies -- Microbial communities. Structural and functional analyses with classical approach -- Microbial communities. Structural and functional analyses with molecular biological approach -- Damage to inorganic materials by microbial activities, biocorrosion -- Biological wastewater treatment -- Biological exhaust air treatment -- Biological soil remediation -- Biological waste treatment -- Biotechnology and environmental protection -- Food for thought.
    Abstract: This textbook addresses global and local environmental problems and the involvement of microorganisms in their development and remediation. In particular, methodological aspects, some of them molecular genetic, for the study of microbial communities are considered. Overall, the prominent role of microorganisms in various material cycles is presented. In addition to biochemical principles for the degradation of environmental pollutants, the use of microorganisms in environmental biotechnological processes for the purification of air, water or soil as well as in environmentally friendly production processes is discussed. The book is intended for biologists with an interest in environmental microbiological issues, but also for students of process or environmental engineering, geoecology or geology, as well as students of other environmental science disciplines. For the 3rd edition, the authors have completely revised, corrected, updated and supplemented the book. The authors Professor Dr. Walter Reineke was Professor of Microbiology at the University of Wuppertal since 1982, where he was involved in teaching both the Food Chemistry and Chemistry courses. He has been retired since August 2013. Professor Dr. Michael Schlömann was appointed Endowed Professor of Environmental Microbiology of the Deutsche Bundesstiftung Umwelt at the Technische Universität Bergakademie Freiberg in 1998 and has been Deputy Director of the University's Interdisciplinary Ecological Centre since 1999. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: XVI, 603 p. 379 illus., 104 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662665473
    URL: https://doi.org/10.1007/978-3-662-66547-3
    DOI: 10.1007/978-3-662-66547-3
    DDC: 579
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    Metabolomics and Its Impact on Health and Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Biochemical markers. ; Cytology. ; Analytical biochemistry. ; Pharmacology. ; Biomarkers. ; Cell Biology. ; Analytical Biochemistry.
    Description / Table of Contents: Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
    Abstract: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
    Type of Medium: Online Resource
    Pages: VIII, 384 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031268595
    Series Statement: Handbook of Experimental Pharmacology, 277
    URL: https://doi.org/10.1007/978-3-031-26859-5
    DOI: 10.1007/978-3-031-26859-5
    DDC: 615
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    Plant Growth Promoting Microorganisms of Arid Region (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Agriculture. ; Ecology . ; Microbiology. ; Agriculture. ; Ecology.
    Description / Table of Contents: 1. Exploring Microbial Diversity of Arid Regions of Globe for Agricultural Sustainability: A Revisit -- 2. Harnessing drought tolerant PGPM in arid agro ecosystem for plant disease management and soil amelioration -- 3. Role of Plant Growth-promoting Bacteria in Rainfed and Irrigated Crops -- 4. Plant Growth Promoting Microbes: The Potential Phosphorus Solubilizers in Soils of Arid Agro-ecosystem -- 5. Diversity of PGPM and Ecosystem Services -- 6. Plant Growth Promoting Microorganisms: An Option for Drought and Salinity Management in Arid Agriculture -- 7. Plant Growth Promoting Microbes: Key Players in Organic Agriculture -- 8. Interceding Microbial Biofertilizers in Agroforestry System for Enhancing Productivity -- 9. Role of PGPM in Managing Soil Borne Plant Pathogens in Horticulture Crops -- 10. The Use of Plant Growth Promoting Microorganisms in the Managementof Soil-Borne Plant Pathogenic Organisms -- 11. Role of plant growth promoting microbes in managing soil-borne pathogens in forestry -- 12. Secondary Metabolites and Bioprospecting -- 13. PGPM: Fundamental, Bioformulation, Commercialization and Success at Farmer’s Field -- 14. PGPR: A Sustainable Agricultural Mitigator For Stressed Agro-Environments -- 15. Endophytic PGPM derived metabolites and their role in arid ecosystem -- 16. Current regulatory requirements for PGPM products for management of seed, soil and plant health: An overview -- 17. Evolving Concepts of Biocontrol of Phytopathogens by Endophytic Pseudomonas fluorescence -- 18. Symbiotic Effectiveness of Rhizobium Strains in Agriculture -- 19. Inoculant Production and Formulation of Azospirillum Species.
    Abstract: This edited book aims to focus on microbial diversity in arid lands and deserts versus specific microbial assemblages associated with plants. The book explains ecological drivers that shape this diversity, how plant-associated microbiomes are selected, and their biotechnological potential are discussed. Diversity and functional redundancy of these associated PGPM make them very active in supporting plant improvement, health and resistance to drought, salt and other stresses, and these dimensions will be explored in this book. Implementing proper biotechnological applications of the arid and desert-adapted PGPM constitutes a sizeable challenge, and the book attempts to take up that challenge and help researchers in this field to gain a detailed understanding of PGPM from arid ecosystems. This book serves as a handbook for research workers, teachers, postgraduate students and extension personnel, other development workers, and policy planners engaged in arid zone development.
    Type of Medium: Online Resource
    Pages: XXII, 455 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811941245
    URL: https://doi.org/10.1007/978-981-19-4124-5
    DOI: 10.1007/978-981-19-4124-5
    DDC: 579
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    Antimicrobial Research and One Health in Africa (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Ecology . ; Environmental health. ; Public health. ; Environmental management. ; Microbial genetics. ; Microbiology. ; Ecology. ; Environmental Health. ; Public Health. ; Environmental Management. ; Microbial Genetics.
    Description / Table of Contents: Preface -- Microbiological safety and antimicrobial resistance in fresh produce production in Africa -- The current status of antibiotic-resistant bacteria and genes in African aquaculture -- Antibiotic resistance in food animals in Africa: Occurrence, human health risk, socio-economic impact, and mitigation measures -- The era of bacterial genomics in antibiotic research in Africa -- Insights Gained Through Genomics and Metagenomics Resistomes Studies in Africa -- Occurrence and health risks of antimicrobial resistance in African aquatic systems -- Antibiotics and antibiotic-resistant bacteria in African coastal ecosystems -- Application of nanotechnology for the elimination of antibiotic-resistant bacteria from wastewater -- Genetics of viral resistance: clinical relevance and role in future disease outbreaks -- Antimicrobial resistance of Salmonella enterica in Africa -- Antimicrobial resistance patterns of ESKAPE pathogens in humans, animals, and the environment in Africa -- Informal settlements and slums: Sinks and sources of antibiotic resistance in Africa -- Antibiotic resistance pattern of bloodstream infections in neonates -- Natural products in combination with conventional antimicrobial agents – A potential solution to antimicrobial resistance -- Biocidal activity of plant extracts: the case of Algeria -- Interconnection between antibiotic resistance and disinfectant resistance -- Effects of disinfectant resistance in a post antibiotic era in animal production -- Antimicrobial Stewardship in Africa -- Occurrence, human exposure, and health risks of antibiotic resistance in the funeral industry: A Perspective -- Social structures and assemblages of AMR in African settings -- Bibliography -- Index.
    Abstract: Antimicrobial resistance is recognised among the world’s most challenging problems. Despite its global spread, Africa, specifically sub-Saharan Africa, is the most affected by this malaise. Poor living conditions and inadequate access to sanitation and potable water supplies are among contributing factors that have influenced a high disease burden on the continent, requiring extensive antimicrobials. Weak health systems and the absence of firm policies further aggravate the problem, as the use of antimicrobials is mostly unregulated. The increasing demand for animal protein to meet the starving populations’ demands has also influenced the use of these antimicrobials, including those banned on other continents, for food animal production. The ripple effect of indiscriminate use in humans and animals is the massive discharge of antimicrobials, their residues, antimicrobial-resistant microorganisms and their associated genes into the environment. This 14-chapter text presents the AMR problem in African, addressing the various compartments of One Health – humans, animals, and the environment, to illustrate the need for concerted efforts in the fight against AMR. Authors from the four cardinal points present diverse aspects of AMR in Africa, starting with behavioural and social drivers of AMR in Africa. Antimicrobial stewardship in an African context is also discussed. AMR in humans is presented through studies on antibiotic-resistant neonates and nontyphoidal Salmonella infections and the clinical relevance of the genetics of viral resistance. Topics on AMR in mastitis, biosecurity in animal farming and the linkage between disinfectants and AMR are discussed. The environmental dimension of AMR is discussed, notably in the aquatic environment, and its implication for aquaculture and irrigation and using nanomaterials to treat polluted waters from such environments are highlighted. Finally, Africa’s rich floral diversity is portrayed as an eco-friendly and cost-effective approach to combat AMR. Hopefully, the work presented will spur greater collaboration between scientists, environmental, animal and human health practitioners, the general population, and policymakers to assimilate and implement the One Health approach to combating AMR, rather than working in silos in their various sectors.
    Type of Medium: Online Resource
    Pages: XVIII, 349 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031237966
    URL: https://doi.org/10.1007/978-3-031-23796-6
    DOI: 10.1007/978-3-031-23796-6
    DDC: 579
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    Non-traditional Approaches to Combat Antimicrobial Drug Resistance (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Medical microbiology. ; Bacteria. ; Microbiology. ; Medical Microbiology. ; Bacteria.
    Description / Table of Contents: Chapter 1. Recent Strategies to Combat Multi-drug Resistance -- Chapter 2. Role of advanced therapeutic techniques to combat multi-drug resistance -- Chapter 3. Strategies to combat multidrug resistance by non-traditional therapeutic approaches -- Chapter 4. Treatment Strategies to Combat Multi-drug Resistance (MDR) in Bacteria -- Chapter 5. Alternative therapy options for pathogenic yeasts: Targeting virulence factors with non-conventional antifungals -- Chapter 6. Role of Bacteriophages as non-traditional approaches to combat multidrug resistance -- Chapter 7. Drug Repurposing: An Approach for Reducing Multi Drug Resistance -- Chapter 8. Quorum Sensing as an alternative approach to combatting multidrug resistance -- Chapter 9. Nanoengineering approaches to fight multidrug resistant bacteria -- Chapter 10. Quorum sensing mediated targeted delivery of antibiotics. Chapter 11. Metal chelation as a promising strategy to combat fungal drug resistance -- Chapter 12. Propolis: Natural Antibiotic to Combat Multi Drug-Resistant Bacteria -- Chapter 13. Therapeutic potential of Himalayan Ayurvedic herbs against multidrug-resistant fungal pathogens -- Chapter 14. Antimicrobial Stewardship Programme: Why is it needed?.
    Abstract: This book provides a detailed overview of the progress and challenges of non-traditional approaches for tackling antimicrobial resistance. The first chapter covers the factors that make microbes more likely to develop multidrug resistance. The book goes on to discuss the antimicrobial properties of propolis, essential oils and other microbial constituents that are used or under investigation to treat multidrug-resistant infections. Additionally, it covers alternative compounds that work as antimicrobial agents, their mechanisms of action, and how they might be utilized in conjunction with conventional drugs to circumvent drug resistance. The book explores the application of phage therapy and recent advancements in phage-based infection control with an emphasis on multidrug-resistant infections and discusses drug repurposing as a strategy to develop new antimicrobial agents efficiently and expeditiously. Additionally, it discusses the uses of nanoparticles in the treatment of infections brought on by multidrug-resistant pathogens and examines the use of different nanotechnology-based approaches to fudge microbial resistance mechanisms. It concludes by reviewing recent studies on microbial quorum-sensing systems and focuses on the significance of quorum-sensing systems in controlling microbial resistance mechanisms and at the same time highlights the importance and role of antimicrobial stewardship program to fight microbial infections. The book is an invaluable source of knowledge and information for academics, basic and clinical researchers, clinicians, and paramedic staff involved in one way or the other in the development and use of antimicrobial agents and strategies to combat multidrug resistance.
    Type of Medium: Online Resource
    Pages: XIII, 320 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811991677
    URL: https://doi.org/10.1007/978-981-19-9167-7
    DOI: 10.1007/978-981-19-9167-7
    DDC: 579
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    Aquaporins (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Proteins . ; Human physiology. ; Biological transport. ; Cell membranes. ; Pharmacology. ; Protein Biochemistry. ; Human Physiology. ; Membrane Trafficking.
    Description / Table of Contents: 1. Classification and Gene Structure of Aquaporins -- 2. Protein Structure and Modification of Aquaporins -- 3. Expression Regulation and Trafficking of Aquaporins -- 4. Transport Characteristics of Aquaporins -- 5. Non-transport Functions of Aquaporins -- 6. The Evolutionary Aspects of Aquaporin Superfamily -- 7. Aquaporins in Nervous System -- 8. Aquaporins in Cardiovascular System -- 9. Aquaporins in Respiratory System -- 10. Aquaporins in Digestive System -- 11. Aquaporins in Urinary System -- 12. Aquaporins in Reproductive System -- 13. Aquaporins in Immune System.-14. Aquaporins in Eye -- 15. Aquaporins in Skin -- 16. Aquaporins in Glandular Secretion -- 17. Aquaporins in Fetal Development -- 18. Aquaporins in Diabetes Insipidus -- 19. Aquaporins in Edema -- 20. Aquaporins in Obesity.-21. Aquaporins in Tumor -- 22. Aquaporin Inhibitors -- 23. Non-aquaporin Water Channels.-24. Methods to Measure Water Permeability.
    Abstract: This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions. In the second version, fourteen chapters will be updated base on the most recent research articles. Ten new chapters will be added.
    Type of Medium: Online Resource
    Pages: VIII, 365 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811974151
    Series Statement: Advances in Experimental Medicine and Biology, 1398
    URL: https://doi.org/10.1007/978-981-19-7415-1
    DOI: 10.1007/978-981-19-7415-1
    DDC: 615
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    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Description / Table of Contents: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Abstract: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Type of Medium: Online Resource
    Pages: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
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    Novel Feedstocks for Biofuels Production (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Refuse and refuse disposal. ; Environmental chemistry. ; Microbiology. ; Waste Management/Waste Technology. ; Environmental Chemistry.
    Description / Table of Contents: 1 Biofuel production from conventional feedstocks: Challenges and alternatives -- 2 Novel feedstocks for biofuels: Current scenario and recent advancements -- 3 Non-edible oil plants for biodiesel production -- 4 Role of Microorganisms in Production of Biofuels -- 5 Algal Biomass for Biodiesel and Bio-oil Production -- 6 Algae as a feedstock for bioethanol and biomethane production -- 7 Aquatic weeds as bioenergy feedstock -- 8 Wastewater and solid waste as feedstock for energy production -- 9 Agricultural lignocellulosic waste for bioethanol production -- 10 -- Food Wastes for Biofuels Production -- 11 Animal Fats Derived Biodiesel and Nano-Technology Applications -- 12 Potential microorganisms for power generation via microbial fuel cells. .
    Abstract: This book critically evaluates recently investigated feedstock for biofuels production. Biofuel sector is rapidly evolving to cater the renewable energy demands. Novel and advanced feedstock are being investigated for their techno-economic feasibility. Environmental concerns, food vs fuel debate, energy security, economic feasibility, and availability are the major drivers for exploring different feedstock for biofuel production. This book explores a wide range of potential biofuels feedstock, their functional concepts, recent advancement, novel technique and critical evaluation with other available biofuel feedstock. This book also discusses future prospects of biofuel production. It is a useful read for students, researchers, faculty, industry and policy makers in the biofuel field.
    Type of Medium: Online Resource
    Pages: XIV, 368 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811935824
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-19-3582-4
    DOI: 10.1007/978-981-19-3582-4
    DDC: 579
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    Forskolin : Natural Sources, Pharmacology and Biotechnology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Clinical biochemistry. ; Medicinal chemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Medicinal Chemistry. ; Pharmacy.
    Description / Table of Contents: Chapter 1. Coleus forskohlii – A multipurpose medicinal plant -- Chapter 2. Botany of Coleus forskohlii -- Chapter 3. Traditional Medicinal Uses and Pharmacognosy of Coleus forskohlii -- Chapter 4. Chemistry of Coleus forskohlii Briq. -- Chapter 5. Pharmacology of Coleus forskohlii and Forskolin -- Chapter 6. Micropropagation of Coleus forskohlii -- Chapter 7. In Vitro Production of Forskolin -- Chapter 8. Assessment of Coleus forskohlii Genetic Diversity Using Molecular Markers -- Chapter 9. Endophytes for the enhanced growth of Coleus forskohlii and enhanced production of Forskolin -- Chapter 10. Propagation Methods of Coleus forskohlii -- Chapter 11. Success stories and Trade and Commerce of Coleus forskohlii.
    Abstract: This monograph compiles updated information about forskolin, a labdane diterpene that is produced by the Coleus plant. Forskolin has a large number of practical uses and the book delves into the various aspects of this chemical. It includes topics such as the botanical source of forskolin and the cultivation of Coleus forskohlii, source. It also covers the biosynthetic pathways in natural sources and also through different biotechnological applications. Chapters include the potential and products in the Forskolin market. The book also covers the methods for enhanced production of forskolin from natural sources and through tissue culture methods for improvement of the plant for higher content of forskolin. It discusses the role of endophytes in the production of forskolin. The book is useful for students and researchers in the field of botany, pharmacology and biochemistry. It also serves scientists in various pharmaceutical industries.
    Type of Medium: Online Resource
    Pages: XI, 177 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811965210
    URL: https://doi.org/10.1007/978-981-19-6521-0
    DOI: 10.1007/978-981-19-6521-0
    DDC: 615
    Language: English
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  • 97
    Online Resource
    Online Resource
    Organic Waste to Biohydrogen (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Biotechnology. ; Bioremediation. ; Microbiology. ; Biotechnology. ; Environmental Biotechnology.
    Description / Table of Contents: Chapter 1. Biohydrogen from the organic fraction of municipal solid waste -- Chapter 2. Biohydrogen from food waste -- Chapter 3. Biohydrogen from fruit and vegetable industry wastes -- Chapter 4. Biohydrogen from Distillery Wastewater: Opportunities and feasibility -- Chapter 5. Biohydrogen from pentose-rich lignocellulosic biomass hydrolysate -- Chapter 6. Biohydrogen Production using Cheese Industry Waste: Current trends and Challenges -- Chapter 7. Methods of biological hydrogen production from industrial waste -- Chapter 8. INNOVATIVE TECHNOLOGIES FOR BIOHYDROGEN PRODUCTION AT INDUSTRIAL LEVEL -- Chapter 9. Thermochemical conversion of lignocellulosic biomass for biohydrogen production -- Chapter 10. Nanotechnological approaches in biohydrogen production -- Chapter 11. Microalgal biomass as a promising feedstock for the production of Biohydrogen: A comprehensive review -- Chapter 12. Biohydrogen: Future energy source for the society.
    Abstract: This book provides an updated knowledge on the biohydrogen production from industrial and municipal organic waste materials. Microbes are increasingly being included in the hydrogen based biofuel production and this book covers the processes and protocols for biohydrogen production. There is an urgent need of alternative energy research to fulfill the global energy demand. Biohydrogen is a promising source of sustainable and clean energy as it harnessed by biological means. Biohydrogen may be produced by utilizing different waste materials as a substrate, and by optimization of various parameters of bioreactors such as temperature, pH, partial pressure etc. The waste materials used in hydrogen production are categorized as agricultural waste, municipal waste, industrial waste, and other hazardous wastes. Biohydrogen production from wastes materials opened a new opportunity for the widespread use of everlasting renewable energy source. This book is useful for professional scientists, academicians, biotechnologist and environmentalist along with research scholars in various biotechnology and bioenergy industries by addressing the latest research going on in the field of renewal bioenergy production from waste and their global impact on the environment.
    Type of Medium: Online Resource
    Pages: XI, 288 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811919954
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-19-1995-4
    DOI: 10.1007/978-981-19-1995-4
    DDC: 579
    Language: English
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  • 98
    Online Resource
    Online Resource
    Rhizosphere Microbes : Biotic Stress Management (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Microbial ecology. ; Stress (Physiology). ; Plants. ; Microbiology. ; Microbial Ecology. ; Plant Stress Responses.
    Description / Table of Contents: Chapter 1. Detection and identification of soil borne pathogens: Classical to Recent updates -- Chapter 2. Microarray-based detection and identification of bacterial and viral plant pathogens -- Chapter 3. Application molecular ecology approaches in sustainable agriculture for a better understanding of plant microbiome interactions -- Chapter 4. Advancements in detection and diagnosis of important soil-borne diseases -- Chapter 5. Omics approaches to revisit rhizo-bacterial biome -- Chapter 6. Engineering the Plant Microbiome for Biotic Stress tolerance: Biotechnological Advances -- Chapter 7. Potential of bacterial endophytes in biological control of soil borne phytopathogens -- Chapter 8. Endophytes: Rendering systemic resistance to plant -- Chapter 9. Arbuscular Mycorrhizal Fungi (AMF) as Potential Biocontrol Agents -- Chapter 10. Rhizosphere microbes and Wheat Health Management -- Chapter 11. Exploring the potential of secondary metabolites from indigenous Trichoderma spp. for their plant growth promotion and disease suppression ability in pulses -- Chapter 12. Uncultivable soil microbes contributing to sustainable agriculture -- Chapter 13. Rhizosphere microbiome: Significance in sustainable crop protection -- Chapter 14. Bacterial inoculants for control of fungal diseases in tomatoes (Solanum lycopersicum L.): A comprehensive overview -- Chapter 15. Plant-Microbe Interaction and Rhizosphere Biology Lab, ICAR-National Bureau of Agriculturally Important -- Chapter 16. Prior weakening as a tool to control soilborne plant pathogens and associated disease pressure.
    Abstract: This edited book volume aims to bringing out a comprehensive collection of latest information and developments on the management of biotic stresses by the use of rhizospheric microbes across the globe. The main focus of this book is to address the scientific and practical significance of rhizosphere microbes in biotic stress management. The microbial communities in the rhizosphere ecosystem play multitude of microbe-microbe, microbe-insect/pest and plant-microbe interactions and they have not yet been fully exploited to gain benefits in this field as well as to achieve sustainability in agriculture. Among the more recent strategies, stress tolerance/resistance induced by environment-friendly elicitors of microbial origin and/or rhizosphere microorganisms has emerged as a promising supplement in the approaches to crop protection. The proposed book entitled "Rhizosphere Microbes: Biotic Stress Management” is pertinent to rhizospheric microbe-mediated biotic stress management covering all spheres of biotic stress tolerance viz., bio-resources, diversity, ecology, and functioning of microbial bio-control agents, host–parasite interaction, strategies to characterize microbial bioinoculants, interactions of rhizosphere microbes by developing a fundamental understanding of the microbial communities, exploration of the diverse roles of microbes and microbial communities and their role in biotic stress tolerance, microbe-mediated mitigation of biotic stresses, quorum sensing, microbial signalling and cross-talk in the rhizosphere, biofilm formation, cell-to-cell communication, role of microorganisms in ecosystems functioning under various biotic stress conditions, application of microbial bio-pesticides, molecular studies using microbial systems, etc. This book is of interest to teachers, researchers, crop protection scientists, capacity builders and policymakers. Also the book serves as additional reading material for under-graduate, post-graduate, and post-doctorate fellow of agriculture, forestry, ecology, life science, and environmental sciences. National and international agricultural scientists, policy makers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XVII, 370 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811958724
    Series Statement: Microorganisms for Sustainability, 40
    URL: https://doi.org/10.1007/978-981-19-5872-4
    DOI: 10.1007/978-981-19-5872-4
    DDC: 579
    Language: English
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  • 99
    Online Resource
    Online Resource
    Opioids : Pharmacology, Abuse, and Addiction (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Neurology . ; Pain medicine. ; Pharmacology. ; Neuroscience. ; Neurology. ; Pain Medicine.
    Description / Table of Contents: Part I. Social aspects of opioid use -- Chapter 1: A brief history of opioids and the evolution of concepts associated with substance use disorders -- Chapter 2: The two sides of opioid use: Unmet needs of opioids for pain management and the role of opioids in substance use disorders -- Chapter 3: Opioid markets and special populations -- Chapter 4: Towards a new drug policy agreement -- Chapter 5: The opioid crises -- Chapter 6: Persons who misuse opioids -- Chapter 7: The need for structural interventions for persons who misuse opioids -- Part II. Pharmacological and medical aspects of opioid use -- Chapter 8: Opioid effects and classification -- Chapter 9: Opioid receptors and neuronal signal transduction -- Chapter 10: Opioids in Pain -- Chapter 11: Opioids in Palliative Care -- Chapter 12: Opioids and the immune system -- Chapter 13: Opioid dependence, tolerance, and withdrawal -- Chapter 14: Medication-Assisted Treatment (MAT) 1: Opioid substitution therapy -- Chapter 15: Medication-Assisted Treatment for Opioid Use Disorders 2. Detoxification -- Chapter 16: Synthetic Opioids as New Psychoactive Substances (NPS).
    Abstract: Opioids are the mainstay in pain treatment and can be invaluable medications in palliative care. However, they are also responsible for the vast majority of preventable deaths related to drug use. This book presents an overview of the social and pharmacological aspects of opioid effects, aiming to provide researchers and health professionals with a firm understanding of their effects and mechanisms of action. The first section reviews the history of opioids from ancient civilizations to the current opioid crisis, gives voice to opioid users through first-hand testimonies, analyzes the existing international drug treatment agreements, and presents structured interventions for persons who misuse opioids. The second section covers state-of-the-art advances in the medical use of opioids, opioid-induced signal transduction, opioids in pain management, opioid use disorders and their treatment. It also presents an updated view of opioids as regulators of inflammation and host defense against pathogens and damage. The overall aim of this book is to provide the reader with a deeper knowledge of this field despite the complexities associated with the existence of numerous ligands, receptor subtypes, and complex pharmacological profiles. To this end, the chapter authors are specialists in the field who also have extensive experience in teaching, hoping to lend their expertise in translating complex concepts into comprehensive and clear explanations.
    Type of Medium: Online Resource
    Pages: XV, 387 p. 36 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031099366
    URL: https://doi.org/10.1007/978-3-031-09936-6
    DOI: 10.1007/978-3-031-09936-6
    DDC: 615
    Language: English
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  • 100
    Online Resource
    Online Resource
    Novel Drug Targets With Traditional Herbal Medicines : Scientific and Clinical Evidence (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Natural products. ; Pharmacology. ; Toxicology. ; Pharmaceutics. ; Medicinal Chemistry. ; Natural Products.
    Description / Table of Contents: Chapter 1: Achillea biebersteinii Afan -- Chapter 2: Aesculus hippocastanum L. -- Chapter 3: Berberis crataegina DC. -- Chapter 4: Calendula officinalis L. -- Chapter 5: Camellia sinensis (L.) Kuntze -- Chapter 6: Capsella bursa-pastoris (L.) Medik. -- Chapter 7: Capsicum annuum L. -- Chapter 8: Cedrus libani A.Rich. -- Chapter 9: Chelidonium majus L. -- Chapter 10: Cichorium intybus L. -- Chapter 11: Cistus laurifolius L. -- Chapter 12: Coriandrum sativum L. -- Chapter 13: Cornus mas L. -- Chapter 14: Curcuma longa L..-Chapter 15: Cydonia oblonga Mill. -- Chapter 16: Cynara scolymus L. -- Chapter 17: Equisetum arvense L. -- Chapter 18: Foeniculum vulgare Mill. -- Chapter 19: Fraxiınus ornus L. -- Chapter 20: Fumaria officinalis L. -- Chapter 21: Helichrysum plicatum DC. -- Chapter 22: Hyoscyamus niger L. -- Chapter 23: Juglans regia L. -- Chapter 24: Laurus nobilis L. -- Chapter 25: Liquidambar orientalis Miller -- Chapter 26: Matricaria chamomilla L. -- Chapter 27: Melissa officinalis L. -- Chapter 28: Momordica charantia L. -- Chapter 29: Nigella sativa L. -- Chapter 30: Olea europaea L. -- Chapter 31: Papaver somniferum L. -- Chapter 32: Rheum ribes L. -- Chapter 33: Rosa canina L. -- Chapter 34: Rosmarinus officinalis L. -- Chapter 35: Silybum marianum L. Gaertn. -- Chapter 36: Urtica dioica L -- Chapter 37: Valeriana officinalis L. -- Chapter 38: Viburnum opulus L.
    Abstract: This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world. It presents the ethnopharmacological records, in vivo and in vitro studies, side effects, chemical compositions and clinical studies of these medicinal plants. Its special focus is on the novel drug targets for disease and their possible mechanisms of action. It covers botanical descriptions the status of the plants, and food or drug interactions including precautions and warnings about the plants and the available market products. It provides an explanation of recorded and known plant administration dosages. Also, the gap between the traditional practice and scientific/clinical evidences in the use of ethnomedicinal plant is acknowledged. It is well known that traditional knowledge of the use of the medicinal plants in therapy is an important resource for the discovery of novel treatment options and drug targets. The main purpose of this book is to draw attention to ethnomedicinal plant species. Data on the therapeutic potentials of these medicinal plants can now be accessed from a single source. It provides an important resource for future research opportunities for harnessing the full potential of these plants.
    Type of Medium: Online Resource
    Pages: XII, 588 p. 119 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031077531
    URL: https://doi.org/10.1007/978-3-031-07753-1
    DOI: 10.1007/978-3-031-07753-1
    DDC: 615
    Language: English
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