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  • 2015-2019  (106)
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  • 1
    Monograph available for loan
    Monograph available for loan
    Groundwater in fractured bedrock environments : managing catchment and subsurface resources (2019)
    London : Geological Society
    Associated volumes
    Details Availability
    Call number: 9/M 07.0421(479)
    In: Geological Society Special Publication, 479
    Description / Table of Contents: Fractured bedrock aquifers have traditionally been regarded as low-productivity aquifers, with only limited relevance to regional groundwater resources. It is now being increasingly recognised that these complex bedrock aquifers can play an important role in catchment management and subsurface energy systems. At shallow to intermediate depth, fractured bedrock aquifers help to sustain surface water baseflows and groundwater dependent ecosystems, provide local groundwater supplies and impact on contaminant transfers on a catchment scale. At greater depths, understanding the properties and groundwater flow regimes of these complex aquifers can be crucial for the successful installation of subsurface energy and storage systems, such as deep geothermal or Aquifer Thermal Energy Storage systems and natural gas or CO2 storage facilities as well as the exploration of natural resources such as conventional/unconventional oil and gas. In many scenarios, a robust understanding of fractured bedrock aquifers is required to assess the nature and extent of connectivity between such engineered subsurface systems at depth and overlying receptors in the shallow subsurface.
    Type of Medium: Monograph available for loan
    Pages: 250 Seiten , Illustrationen
    ISBN: 978-1-78620-401-1
    ISSN: 0305-8719 (Print) , 2041-4927 (ebook)
    Series Statement: Geological Society Special Publication 479
    URL: https://sp.lyellcollection.org/content/479/1
    Language: English
    Note: Contents OFTERDINGER, U., MACDONALD, A. M., COMTE, J.-C. & YOUNG, M. E. Groundwater in fracturedbedrock environments: managing catchment and subsurface resources–an introduction .....1 FOUCHÉ, O., YAO,TH. K., OGA, M.-S. Y. & SORO, N. Typology of hard rock ground waterswithin the Lower Sassandra, a main catchment in humid tropical West Africa .....................................11 COMTE, J.-C., OFTERDINGER, U., LEGCHENKO, A., CAULFIELD, J., CASSIDY,R.&MÉZQUITAGONZÁLEZ, J. A. Catchment-scale heterogeneity offlow and storage propertiesin a weathered/fractured hard rock aquifer from resistivity and magnetic resonance surveys: implications for groundwaterflow paths and the distribution of residence times ........................................................................35 VASSEUR,G.&LACHASSAGNE, P. Evaluation of the geothermal effects caused by the weatheringof crystalline rocks ....................59 MACDONALD,A.M.&DAVIES, J. Fractures in shale: the significance of igneous intrusions forgroundwaterflow .....................................71 DICKSON, N. E. M., COMTE, J.-C., KOUSSOUBE, Y., OFTERDINGER,U.S.&VOUILLAMOZ, J.-M.Analysis and numerical modelling of large-scale controls on aquifer structure andhydrogeological properties in the African basement (Benin, West Africa) .....................................................................................81 PARKER, B. L., CHAPMAN, S. W., GOLDSTEIN,K.J.&CHERRY, J. A. Multiple lines offieldevidence to inform fracture network connectivity at a shale site contaminated with densenon-aqueous phase liquids ..........................................................................101 STROEBEL, D. H., THIART,C.&DEWIT, M. Towards defining a baseline status of scarcegroundwater resources in anticipation of hydraulic fracturing in the Eastern Cape Karoo,South Africa: salinity, aquifer yields and groundwater levels ........................................129 BAIOCCHI, A., LOTTI, F., PISCOPO,V.&SAMMASSIMO, V. Hard-rock aquifer response topumping and sustainable yield of wells in some areas of Mediterranean Region ........................................147 NEWTON, C. J. Fracture and conduit controls on groundwater movementin the Carboniferous Limestone of the eastern Mendip Hills, Somerset, England .........................................................161 KENNEL,J.R.&PARKER, B. L. Acoustic televiewer amplitude data for porosity estimationwith application to porewater conversion ....177 BELLE, P., LACHASSAGNE, P., MATHIEU, F., BARBET, C., BRISSET,N.&GOURRY, J.-C.Characterization and location of the laminated layer within hard rock weathering profilesfrom electrical resistivity tomography: implications for water well siting ..............187 PARKER, B. L., BAIROS, K., MALDANER, C. H., CHAPMAN, S. W., TURNER, C. M.,BURNS, L. S., PLETT, J., CARTER, R.&CHERRY, J. A. Metolachlor dense non-aqueous phaseliquid source conditions and plume attenuation in a dolostone water supply aquifer ................................................................207 ADEKILE,D.&CARTER, R. James Robert Temple Hazell: A Pioneer of African Hydrogeology ...........................................................237 Index .....................................................................................245
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  • 2
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    Groundwater in Fractured Bedrock Environments : Managing Catchment and Subsurface Resources (2019)
    London : The Geological Society
    Details
    Keywords: fractured bedrock ; aquifers ; groundwater
    Description / Table of Contents: Groundwater in fractured bedrock environments: managing catchment and subsurface resources – an introduction / U. Ofterdinger, A. M. MacDonald, J.-C. Comte and M. E. Young / Geological Society, London, Special Publications, 479, 1-9, 30 April 2019, https://doi.org/10.1144/SP479-2018-170 --- Typology of hard rock ground waters within the Lower Sassandra, a main catchment in humid tropical West Africa / O. Fouché, Th. K. Yao, M.-S. Y. Oga and N. Soro / Geological Society, London, Special Publications, 479, 11-33, 21 May 2018, https://doi.org/10.1144/SP479.5 --- Catchment-scale heterogeneity of flow and storage properties in a weathered/fractured hard rock aquifer from resistivity and magnetic resonance surveys: implications for groundwater flow paths and the distribution of residence times / J.-C. Comte, U. Ofterdinger, A. Legchenko, J. Caulfield, R. Cassidy and J. A. Mézquita González / Geological Society, London, Special Publications, 479, 35-58, 10 May 2018, https://doi.org/10.1144/SP479.11 --- Evaluation of the geothermal effects caused by the weathering of crystalline rocks / Guy Vasseur and Patrick Lachassagne / Geological Society, London, Special Publications, 479, 59-70, 8 May 2018, https://doi.org/10.1144/SP479.1 --- Fractures in shale: the significance of igneous intrusions for groundwater flow / Alan M. MacDonald and Jeff Davies / Geological Society, London, Special Publications, 479, 71-79, 17 April 2018, https://doi.org/10.1144/SP479.10 --- Analysis and numerical modelling of large-scale controls on aquifer structure and hydrogeological properties in the African basement (Benin, West Africa) / Neil E. M. Dickson, Jean-Christophe Comte, Youssouf Koussoube, Ulrich S. Ofterdinger and Jean-Michel Vouillamoz / Geological Society, London, Special Publications, 479, 81-100, 8 May 2018, https://doi.org/10.1144/SP479.2 --- Multiple lines of field evidence to inform fracture network connectivity at a shale site contaminated with dense non-aqueous phase liquids / Beth L. Parker, Steven W. Chapman, Kenneth J. Goldstein and John A. Cherry / Geological Society, London, Special Publications, 479, 101-127, 17 April 2018, https://doi.org/10.1144/SP479.8 --- Towards defining a baseline status of scarce groundwater resources in anticipation of hydraulic fracturing in the Eastern Cape Karoo, South Africa: salinity, aquifer yields and groundwater levels / Divan H. Stroebel, Christien Thiart and Maarten de Wit / Geological Society, London, Special Publications, 479, 129-145, 8 May 2018, https://doi.org/10.1144/SP479.3 --- Hard-rock aquifer response to pumping and sustainable yield of wells in some areas of Mediterranean Region / Antonella Baiocchi, Francesca Lotti, Vincenzo Piscopo and Valentina Sammassimo / Geological Society, London, Special Publications, 479, 147-160, 28 March 2018, https://doi.org/10.1144/SP479.4 --- Fracture and conduit controls on groundwater movement in the Carboniferous Limestone of the eastern Mendip Hills, Somerset, England / Christopher J. Newton / Geological Society, London, Special Publications, 479, 161-176, 25 April 2019, https://doi.org/10.1144/SP479-2017-52 --- Acoustic televiewer amplitude data for porosity estimation with application to porewater conversion / J. R. Kennel and B. L. Parker / Geological Society, London, Special Publications, 479, 177-185, 3 May 2018, https://doi.org/10.1144/SP479.6 --- Characterization and location of the laminated layer within hard rock weathering profiles from electrical resistivity tomography: implications for water well siting / Pierre Belle, Patrick Lachassagne, Francis Mathieu, Christine Barbet, Nicolas Brisset and Jean-Christophe Gourry / Geological Society, London, Special Publications, 479, 187-205, 8 May 2018, https://doi.org/10.1144/SP479.7 --- Metolachlor dense non-aqueous phase liquid source conditions and plume attenuation in a dolostone water supply aquifer / Beth L. Parker, Kenley Bairos, Carlos H. Maldaner, Steven W. Chapman, Christopher M. Turner, Leanne S. Burns, James Plett, Raymond Carter and John A. Cherry / Geological Society, London, Special Publications, 479, 207-236, 21 May 2018, https://doi.org/10.1144/SP479.9 --- James Robert Temple Hazell: A Pioneer of African Hydrogeology / Dotun Adekile and Richard Carter / Geological Society, London, Special Publications, 479, 237-243, 15 October 2018, https://doi.org/10.1144/SP479.12
    Pages: Online-Ressource (250 Seiten) , Illustrationen, Diagramme
    ISBN: 9781786204011
    URL: https://sp.lyellcollection.org/content/479/1
    Language: English
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  • 3
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    Heterodimensional charge-carrier confinement in stacked submonolayer InAs in GaAs (2016)
    American Physical Society
    Details
    Publication Date: 2016-02-02
    Print ISSN: 2469-9950
    Electronic ISSN: 2469-9969
    Topics: Physics
    Published by American Physical Society
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  • 4
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    Role of IL11 in placentation and preeclampsia [Developmental Biology] (2015)
    National Academy of Sciences
    Details
    Publication Date: 2015-12-30
    Description: Preeclampsia (PE) is a pregnancy-specific disorder characterized by hypertension and proteinuria after 20 wk gestation. Abnormal extravillous trophoblast (EVT) invasion and remodeling of uterine spiral arterioles is thought to contribute to PE development. Interleukin-11 (IL11) impedes human EVT invasion in vitro and is elevated in PE decidua in women. We...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 5
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    Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways (2018)
    National Academy of Sciences
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    Publication Date: 2018-06-18
    Description: Membrane receptors regulate numerous intracellular functions. However, the molecular underpinnings remain poorly understood because most receptors initiate multiple signaling pathways through distinct interaction interfaces that are structurally uncharacterized. We present an integrated computational and experimental approach to model and rationally engineer membrane receptor-intracellular protein systems signaling with novel pathway selectivity. We targeted the dopamine D2 receptor (D2), a G-protein–coupled receptor (GPCR), which primarily signals through Gi, but triggers also the Gq and beta-arrestin pathways. Using this approach, we designed orthogonal D2–Gi complexes, which coupled with high specificity and triggered exclusively the Gi-dependent signaling pathway. We also engineered an orthogonal chimeric D2–Gs/i complex that rewired D2 signaling from a Gi-mediated inhibitory into a Gs-dependent activating pathway. Reinterpreting the evolutionary history of GPCRs in light of the designed proteins, we uncovered an unforeseen hierarchical code of GPCR–G-protein coupling selectivity determinants. The results demonstrate that membrane receptor–cytosolic protein systems can be rationally engineered to regulate mammalian cellular functions. The method should prove useful for creating orthogonal molecular switches that redirect signals at the cell surface for cell-engineering applications.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 6
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    POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity (2015)
    Oxford University Press
    Details
    Publication Date: 2015-08-27
    Description: Human mitochondrial DNA (mtDNA) is replicated and repaired by the mtDNA polymerase gamma, pol. Pol is composed of three subunits encoded by two nuclear genes: (1) POLG codes for the 140-kilodalton (kDa) catalytic subunit, p140 and (2) POLG2 encodes the ~110-kDa homodimeric accessory subunit, p55. Specific mutations are associated with POLG - or POLG2 -related disorders. During DNA replication the p55 accessory subunit binds to p140 and increases processivity by preventing pol's dissociation from the template. To date, studies have demonstrated that homodimeric p55 disease variants are deficient in the ability to stimulate p140; however, all patients currently identified with POLG2 -related disorders are heterozygotes. In these patients, we expect p55 to occur as 25% wild-type (WT) homodimers, 25% variant homodimers and 50% heterodimers. We report the development of a tandem affinity strategy to isolate p55 heterodimers. The WT/G451E p55 heterodimer impairs pol function in vitro , demonstrating that the POLG2 c.1352G〉A/p.G451E mutation encodes a dominant negative protein. To analyze the subcellular consequence of disease mutations in HEK293 cells, we designed plasmids encoding p55 disease variants tagged with green fluorescent protein (GFP). P205R and L475DfsX2 p55 variants exhibit irregular diffuse mitochondrial fluorescence and unlike WT p55, they fail to form distinct puncta associated with mtDNA nucleoids. Furthermore, homogenous preparations of P205R and L475DfsX2 p55 form aberrant reducible multimers. We predict that abnormal protein folding or aggregation or both contribute to the pathophysiology of these disorders. Examination of mitochondrial bioenergetics in stable cell lines overexpressing GFP-tagged p55 variants revealed impaired mitochondrial reserve capacity.
    Print ISSN: 0964-6906
    Electronic ISSN: 1460-2083
    Topics: Biology , Medicine
    Published by Oxford University Press
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  • 7
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    Reproducible Research in Vadose Zone Sciences (2015)
    Soil Science Society of America (SSSA)
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    Publication Date: 2015-10-13
    Description: A significant portion of present-day soil and Earth science research is computational, involving complex data analysis pipelines, advanced mathematical and statistical models, and sophisticated computer codes. Opportunities for scientific progress are greatly diminished if reproducing and building on published research is difficult or impossible due to the complexity of these computational systems. Vadose Zone Journal (VZJ) is launching a Reproducible Research (RR) program in which code and data underlying a research article will be published alongside the article, thereby enabling readers to analyze data in a manner similar to that presented in the article and build on results in future research and applications. In this article, we discuss reproducible research, its background and use across other disciplines, its value to the scientific community, and its implementation in VZJ.
    Electronic ISSN: 1539-1663
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Soil Science Society of America (SSSA)
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  • 8
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    Measurements of hydrogen, oxygen and carbon isotope variability in Sphagnum moss along a micro-topographical gradient in a southern Patagonian peatland (2016)
    Wiley
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    Publication Date: 2016-06-18
    Description: ABSTRACT Peat archives offer a diverse range of physical and chemical proxies from which it is possible to study past environmental and ecological changes. Direct numerical calibration and verification is difficult so process-based and mechanistic studies are therefore required to establish and quantify links between environmental changes and their associated proxy-responses. Traditional ‘space-for-time’ calibrations provide a solution to this calibration problem, but are often unable to isolate a single environmental variable from other potentially confounding variables. In this study, we explored the potential of a site-specific ‘space-for-time’ approach applied to a hummock-hollow transect on an ombrotrophic raised bog in Patagonia, southern Chile. Coupled stable carbon, oxygen and hydrogen isotopic measurements were made on individual samples of Sphagnum moss cellulose and compared with plant-associated waters, local hydrology, temperature and relative humidity, sampled at the same points along the study transect. Results reveal a range of environmental responses, which were supported by plant-physiological models in the case of carbon and oxygen isotopes. For hydrogen isotopes, the results obtained from cellulose indicated a need for further research into hydrogen isotope fractionation in Sphagnum . We recommend conducting site-specific characterization of plant response to support the development of peat-based isotope records for palaeoenvironmental research, and where logistically possible, that monitoring is conducted over timescales appropriate to the time-integrative nature of the Sphagnum record.
    Print ISSN: 0267-8179
    Electronic ISSN: 1099-1417
    Topics: Geography , Geosciences
    Published by Wiley
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  • 9
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    Superresolved multiphoton microscopy [Applied Physical Sciences] (2016)
    National Academy of Sciences
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    Publication Date: 2016-06-15
    Description: Superresolved far-field microscopy has emerged as a powerful tool for investigating the structure of objects with resolution well below the diffraction limit of light. Nearly all superresolution imaging techniques reported to date rely on real energy states of fluorescent molecules to circumvent the diffraction limit, preventing superresolved imaging with contrast...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 10
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    Healthy human gut phageome [Microbiology] (2016)
    National Academy of Sciences
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    Publication Date: 2016-09-14
    Description: The role of bacteriophages in influencing the structure and function of the healthy human gut microbiome is unknown. With few exceptions, previous studies have found a high level of heterogeneity in bacteriophages from healthy individuals. To better estimate and identify the shared phageome of humans, we analyzed a deep DNA...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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