Publication Date:
2016-08-03
Description:
Article BRAF inhibitors often show skin-hyperproliferative side effects in melanoma patients. Here, the authors demonstrate that BRAF inhibitors can be used to enhance skin wound healing through the MAPK- ERK pathway activation that positively regulates the proliferation of keratinocytes. Nature Communications doi: 10.1038/ncomms12348 Authors: Helena Escuin-Ordinas, Shuoran Li, Michael W. Xie, Lu Sun, Willy Hugo, Rong Rong Huang, Jing Jiao, Felipe Meira de-Faria, Susan Realegeno, Paige Krystofinski, Ariel Azhdam, Sara Marie D. Komenan, Mohammad Atefi, Begoña Comin-Anduix, Matteo Pellegrini, Alistair J. Cochran, Robert L. Modlin, Harvey R. Herschman, Roger S. Lo, William H. McBride, Tatiana Segura, Antoni Ribas
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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