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  • 1
    Electronic Resource
    Electronic Resource
    Random Structural Models for Double Dynamic Programming Score Evaluation (1997)
    Springer
    Journal of molecular evolution 44 (1997), S. S174 
    Details
    ISSN: 1432-1432
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00000069
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  • 2
    Electronic Resource
    Electronic Resource
    A flexible method to align large numbers of biological sequences (1988)
    Springer
    Journal of molecular evolution 28 (1988), S. 161-169 
    Details
    ISSN: 1432-1432
    Keywords: Multiple protein sequence consensus ; Alignment ; Evolutionary tree ; Clustering
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A method for the alignment of two or more biological sequences is described. The method is a direct extension of the method of Taylor (1987) incorporating a consensus sequence approach and allows considerable freedom in the control of the clustering of the sequences. At one extreme this is equivalent to the earlier method (Taylor 1987), whereas at the other, the clustering approaches the binary method of Feng and Doolittle (1987). Such freedom allows the program to be adapted to particular problems, which has the important advantage of resulting in considerable savings in computer time, allowing very large problems to be tackled. Besides a detailed analysis of the alignment of the cytochrome c superfamily, the clustering and alignment of the PIR sequence data bank (3500 sequences approx.) is described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02143508
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  • 3
    Electronic Resource
    Electronic Resource
    A deeply knotted protein structure and how it might fold (2000)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 406 (2000), S. 916-919 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The search for knots in protein has uncovered little that would cause Alexander the Great to reach for his sword. Excluding knots formed by post-translational crosslinking, the few proteins considered to be knotted form simple trefoil knots with one end of the chain extending through a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/35022623
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  • 4
    Electronic Resource
    Electronic Resource
    A ‘periodic table’ for protein structures (2002)
    [s.l.] : Nature Publishing Group
    Nature 416 (2002), S. 657-660 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Current structural genomics programs aim systematically to determine the structures of all proteins coded in both human and other genomes, providing a complete picture of the number and variety of protein structures that exist. In the past, estimates have been made on the basis of the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/416657a
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  • 5
    Electronic Resource
    Electronic Resource
    Protein knots: A tangled problem (2003)
    [s.l.] : Nature Publishing Group
    Nature 421 (2003), S. 25-25 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...From our experiences with shoelaces, we tend to think that tying a knot requires both dexterity and intent. As proteins lack both of these qualities, it was assumed for many years that there would be few, if any, knots found in protein chains. But perhaps shoelaces are not a good model for ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/421025a
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  • 6
    Electronic Resource
    Electronic Resource
    Stirring the primordial soup (2005)
    [s.l.] : Nature Publishing Group
    Nature 434 (2005), S. 705-705 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It is now widely believed that almost four billion years ago, before the first living cells, life consisted of assemblies of self-reproducing macromolecules. The molecular candidate thought to mediate this activity was RNA, which can combine the necessary properties of encoding information and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/434705a
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  • 7
    Electronic Resource
    Electronic Resource
    Support for shared ancestry of GAPs (1998)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 392 (1998), S. 448-448 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The Ras superfamily of monomeric GTPase proteins comprises six subfamilies, each with specific cellular functions, but all these subfamilies share a common fold and a common mechanism for hydrolysing GTP. Unlike their cognate guanine-nucleotide-binding (G) proteins, GTPase-activating proteins ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/33043
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  • 8
    Electronic Resource
    Electronic Resource
    Some comments on the limb shift of solar lines (1980)
    Springer
    Solar physics 68 (1980), S. 41-47 
    Details
    ISSN: 1573-093X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We searched for a variation with heliographic latitude of the solar limb effect by comparing the relative wavelengths of weak and strong Fraunhofer lines. The blue shifts associated with the limb effect appear 9%±5% larger in the polar radius vector than in an equatorial radius vector at cos θ = 0.5. This should perhaps be interpreted as an increase with latitude of either solar convection or of convective overshoot. Recent observations of poleward meridional flows of 30m s−1 should be corrected for this limb effect variation. This correction increases this flow velocity to ∼70 m s−1. A search for a similar variation in plages and in network boundaries had negative results, the variation being +1%±5% and -1%±6% respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00153265
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  • 9
    Electronic Resource
    Electronic Resource
    Life's forms (1995)
    [s.l.] : Nature Publishing Group
    Nature 375 (1995), S. 372-372 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] "WHAT is the secret of life?" I asked. . . . "Protein", the bartender declared. "They found out something about protein." The storyteller in Kurt Vonnegut's novel Cat's Cradle, having posed the ultimate biological question, unfortunately did not pursue the bartender's ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/375372a0
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  • 10
    Electronic Resource
    Electronic Resource
    Analysis and prediction of protein β -sheet structures by a combinatorial approach (1980)
    [s.l.] : Nature Publishing Group
    Nature 285 (1980), S. 378-382 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Analysis of β-sheet sandwiches (for example immunoglobulin domains) suggests an algorithm that successfully predicts the tertiary fold of these proteins from their sequence and secondary structure. We propose tertiary structures for β2- microglobulin and an HLA-B7 antigen ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/285378a0
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