ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Chemical treatment of polycaprolactone was carried out to bioactivite thebiodegradable polymer for bone tissue engineering application. The results show that surfacemodifications are necessary to introduce functional groups such as carboxylic groups for theeffective induction of apatite nucleation, prior to SBF treatment. The functional groups, actingas anchors between the polymer and the apatite nuclei, dictate the duration of the inductionperiod need for apatite nucleation. After the surface treatment with sodium hydroxide solution,the apatite nuclei will form and grow spontaneously into a dense and uniform layer of apatite,by taking up Ca2+ and PO42- ions that are present in the SBF, as SBF is supersaturated withrespect to apatite. Similar surface treatment was applied to electrospun PCL nanofibres.Biomimetic apatite/PCL nanofibres were formed which can potentially be used as bone tissueengineering scaffolds
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.991.pdf
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