Publication Date:
2014-02-22
Description:
Article Defects in the homologous recombination repair of DNA can result in gene mutation and cancer. In this study, Peng et al. identify a gene signature associated with homologous recombination repair deficiency and show that this can be used both to predict repair defects and clinical outcome in cancer patients. Nature Communications doi: 10.1038/ncomms4361 Authors: Guang Peng, Curtis Chun-Jen Lin, Wei Mo, Hui Dai, Yun-Yong Park, Soo Mi Kim, Yang Peng, Qianxing Mo, Stefan Siwko, Ruozhen Hu, Ju-Seog Lee, Bryan Hennessy, Samir Hanash, Gordon B. Mills, Shiaw-Yih Lin
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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