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  • 1
    Electronic Resource
    Electronic Resource
    A study on mechanical deformation of highly oriented poly(oxymethylene) by vibrational spectroscopy and X-ray diffraction: stress and temperature dependences of Young's modulus (1989)
    s.l. : American Chemical Society
    Macromolecules 22 (1989), S. 758-765 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00192a041
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  • 2
    Electronic Resource
    Electronic Resource
    High-resolution shallow seismic and ground penetrating radar investigations revealing the evolution of the Uemachi Fault system, Osaka, Japan (2004)
    Melbourne, Australia : Blackwell Science Pty
    The @island arc 13 (2004), S. 0 
    Details
    ISSN: 1440-1738
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Abstract  Ground penetrating radar (GPR) and high-resolution shallow reflection seismic surveying were carried out to investigate the subsurface geology in and around the Uemachi Fault zone in the Yamato River area, Osaka, Japan. Shallow drilling in the area showed a major displacement event during the middle Pleistocene. The main Uemachi Fault plane could be clearly imaged on the seismic section, except for the most shallow 200 m. Several shallow normal fault planes with less displacement could be detected on both sides of the fault plane. GPR profiles confirmed the presence of several shallow normal faults within the area near the fault zone. These shallow faults could be followed in all of the GPR profiles crossing the fault zone. The integration of seismic section, GPR profiles and drilling data led to a conceptual model that explains the evolution of the Uemachi Fault system. The proposed model suggests the occurrence of several cycles of small vertical displacement along the deep part of the fault plane caused by the regional east–west compressional stress. The ductile nature of the shallow sedimentary cover and the absence of confining pressure in the shallow part allow for a considerable amount of plastic bending before failing in the shallow sedimentary layers. This bending generates stretching force within the shallow sedimentary cover, which in time, along with gravitational force, gives rise to the formation of the swarm of normal faults within the shallow layers near the fault zone. Some of the detected faults extend to a depth of less than 3 m below the ground surface, suggesting that the last tectonic activity along the fault plane may have occurred recently.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1738.2003.00418.x
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  • 3
    Electronic Resource
    Electronic Resource
    Separation of fine particles using rotating tube with alternate flow (1986)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 57 (1986), S. 2859-2861 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A new method for selective separation of fine particles was developed by using a rotating tube with alternate flow (RAF). The separation is performed in the condition of negligible small of the centrifugal force of a particle compared to gravity. In the horizontal tube with stable flow, each particle moves along the flow drawing a helical path. The locus of each particle depends on a parameter Aω/V0, where A is a radius of the tube, ω is its angular velocity, and V0 is the sedimentation velocity in a liquid at fixed temperature. The velocity along the flow is determined by the locus and the distribution of the flow speed in the tube. The ratio V/Umax (where V is the particle velocity and Umax is the flow speed at the tube center) was obtained theoretically and experimentally. The value took the maximum at Aω/V0(approximately-equal-to)2 and decreased near exponentially within the range of Aω/V0(approximately-greater-than)2.5 and precipitously decreased within Aω/V0(approximately-less-than)2. By using an alternate flow method with suitable rotation for each directional flow, large particles were taken out successively in descending order of the size from one end and small ones in ascending order from the other end.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139056
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  • 4
    Electronic Resource
    Electronic Resource
    Fabrication of low-loss and high-Δn single-mode fluoride fiber for 1.3 μm praseodymium-doped fiber amplifiers (1995)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 67 (1995), S. 3063-3065 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The crystallization properties of ZrF4-based fluoride glasses containing PbF2 are clarified and single-mode fibers for an optical amplifier operating at 1.3 μm are fabricated. The crystallization tendency increases as the PbF2 content of the glasses increases and the optimum PbF2 content ranges from 11 to 12.5 mol % in terms of glass stability and refractive indices. The 4%-Δn single-mode fiber with a transmission loss of 44 dB/km at 1.2 μm was prepared as the amplifier host fiber. ZrF4-based glass with a PbF2 content of 11 mol % was used as a core glass and HfF4-based glass was used as a cladding glass. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.114865
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  • 5
    Electronic Resource
    Electronic Resource
    Kinetics of complexation of nickel (II) and copper (II) with some azophenol derivatives in aqueous nonionic surfactant solution (1992)
    Springer
    Microchimica acta 106 (1992), S. 75-82 
    Details
    ISSN: 1436-5073
    Keywords: kinetics of complexation ; azophenol derivatives ; micellar solution of Triton X-100 ; partition constants ; copper(II) and nickel(II)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The kinetics of formation of 1∶1 complexes of nickel(II) and copper(II) ions with some azophenol derivatives in aqueous and micellar solution of a nonionic surfactant, Triton X-100, have been studied by a stopped-flow spectrophotometric method. Second order rate constants for the reactions were determined at 298 K and ionic strength 0.1 (NaClO4) in aqueous solution. In the surfactant solution, the pseudo-first-order rate constants for the complexation reactions,k′obs, decreased with increasing the concentration of Triton X-100. This observation was explained by the assumption that the chelating reagents distribute between the micelle of the surfactant and bulk aqueous phase and rate-controlling reactions occur only in the bulk aqueous phase. On the basis of the relation betweenk′obs and the concentration of the surfactant, the partition constants of the reagents between micellar and aqueous phases were determined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01242701
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  • 6
    Electronic Resource
    Electronic Resource
    Change of complement C1s synthesis during development of hamster cartilage (1996)
    Springer
    Cell & tissue research 285 (1996), S. 199-204 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Bone ; Ossification ; Cartilage ; Chondrocytes ; Complement C1s ; Development ; Immunohistochemistry ; In situ hybridization ; Hamster
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Expression of the first complement component (C1s) has been examined in chondrocytes of hamster epiphyseal cartilage during development and fracture healing. C1s is immunostained with anti-hamster C1s monoclonal antibody, PG11. The C1s staining increases in accordance with chondrocyte differentiation and reaches a maximal level in hypertrophic chondrocytes. This change is observed at both the tibia ossification center and at the callus in which the replacement of cartilage by bone marrow takes place. The concomitant increase of C1s and chondrocyte hypertrophy has been confirmed by RNA blot and by in situ hybridization. These results, in addition to previous findings on C1s collagenolytic and gelatinolytic activities, suggest C1s participation in cartilage remodeling.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004410050637
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  • 7
    Electronic Resource
    Electronic Resource
    Coordinated change between complement C1s production and chondrocyte differentiation in vitro (1997)
    Springer
    Cell & tissue research 289 (1997), S. 299-305 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Complement C1s ; Sandwich ELISA ; Chondrocytes ; Cell culture ; Differentiation ; Ascorbic acid ; Syrian hamster ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. In vitro synthesis of the first component of complement C1s was examined by using hamster epiphyseal chondrocytes (HAC) and human chondrosarcoma cell line HCS-2/8. Hamster and human C1s produced by the cells were quantified by immunoblotting and sandwich enzyme-linked immunosorbent assay (ELISA), respectively. It was possible to measure active and inactive C1s by sandwich ELISA, when we used anti-human C1s monoclonal antibodies, M241 recognizing only active C1s, and M365 and M81 recognizing both active and inactive C1s. Approximately 40% of C1s secreted from HCS-2/8 was found to be activated in the culture medium, whereas C1s from HAC was not. C1s production increased in accordance with chondrocyte differentiation induced by ascorbic acid. In contrast, transforming growth factor-beta1 and basic fibroblast growth factor, which inhibited differentiation, suppressed C1s production. These results confirmed our previous observation showing that C1s synthesis increased with differentiation into hypertrophic chondrocytes in vivo.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004410050876
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  • 8
    Electronic Resource
    Electronic Resource
    Metabolic activities of partially degenerated hypertrophic chondrocytes: gene expression of hyaluronan synthases (1999)
    Springer
    Cell & tissue research 298 (1999), S. 317-325 
    Details
    ISSN: 1432-0878
    Keywords: Cartilage Hypertrophic chondrocytes Differentiation Hyaluronan Hyaluronan synthases In situ hybridization Golden hamster Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Ultrastructural aspects of hypertrophic chondrocytes in hamster and mouse epiphysial cartilage were examined in relation to their metabolic activities. With the hypertrophic change, cytoplasmic vacuolization proceeded leaving the partially intact endoplasmic reticulum (ER). In the hypertrophic cells, cytoplasmic hyaluronan was stained with the biotinylated hyaluronan-binding region (b-HABR) of aggrecan, and mRNAs of hyaluronan synthase (Has 1, Has 2 and Has 3) were detected by in situ hybridization. When the epiphysial cartilage was cultured in the presence of 35S, 3H-GlcNAc, 3H-proline or 14C-palmitic acid, vacuolated late hypertrophic chondrocytes were labeled with these radioactive precursors. The evidence indicates that late hypertrophic chondrocytes are metabolically active, which appears to be essential for the enlargement of chondrocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004419900082
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  • 9
    Electronic Resource
    Electronic Resource
    Complement Cls, a classical enzyme with novel functions at the endochondral ossification center: immunohistochemical staining of activated Cls with a neoantigen-specific antibody (1997)
    Springer
    Cell & tissue research 288 (1997), S. 557-565 
    Details
    ISSN: 1432-0878
    Keywords: Key words: Complement Cls ; Neoantigen ; Cartilage ; Hypertrophic chondrocyte ; Immunohistochemistry ; Rheumatoid arthritis ; Decorin ; Syrian hamster ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The secondary ossification center of 14- to 16-day-old hamster tibiae was examined immunohistochemically with active and inactive Cls-specific antibodies, RK5 and RK4, respectively. At the ossification center, chondrocytes differentiate from proliferating and hypertrophic to degenerating stages, and their site is occupied by the bone marrow. Cls was strongly immunostained in hypertrophic chondrocytes. In order to discover whether Cls is activated at a particular site, the cartilage was immunostained with RK5 and RK4. RK5 mainly reacted with degrading matrix around invading vessels. In contrast, RK4 strongly stained hypertrophic chondrocytes. Immunoelectron microscopy revealed Cls on degrading fragments of chondrocytes and fibers of cartilage matrix. Decorin, one of the major matrix proteoglycans, was dose and time dependently degraded by Cls. Type II collagen and type I gelatin were also degraded. Articular cartilage from patients with rheumatoid arthritis was positively immunostained (11/12 cases) with an anti-Cls monoclonal antibody (mAb) PG11, whereas normal articular cartilage (5/5 cases) was negative, suggesting Cls participation in the etiology of rheumatoid arthritis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004410050841
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  • 10
    Electronic Resource
    Electronic Resource
    Inhibition of bFGF activity by complement C1s: covalent binding of C1s with bFGF (1998)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 16 (1998), S. 159-163 
    Details
    ISSN: 0263-6484
    Keywords: bFGF ; complement C1s ; HUVEC ; covalent binding ; growth inhibition ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The first complement component C1s formed large aggregates with bFGF when bFGF and C1s were incubated at 37°C overnight. Under non-reducing conditions, a part of the aggregates did not penetrate into 5% polyacrylamide gel in the presence of SDS, and the rest penetrated into 5% gel but not into 12% gel. The aggregates were dissociated into monomers by reducing with 2-mercaptoethanol. Both active and inactive C1s formed aggregates with bFGF. In addition, a portion of bFGF was degraded by active C1s but not by inactive C1s. Aggregates were not formed when 2-mercaptoethanol (2 mM&base;) was added to the incubation mixture. After the incubation with C1s the growth-stimulating activity of bFGF was measured by using human umbilical vein endothelial cells (HUVEC) as indicator cells. The aggregate formation between C1s and bFGF significantly reduced the activity of bFGF. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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