ISSN:
1573-8388
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Abstract A description is given of the directed synthesis of (±)-recifeiolide (VI), starting from cyclooctene and 1-chlorobutan-3-ol. The ozonolysis of cyclooctene gave 7-for-mylheptanoic acid, the methyl ester of which (II) was condensed with the ylide of (3-hydroxybut-1-yl) triphenylphosphonium iodide (I) synthesized from 1-chlorobutan-3-ol. The lactonization of the 11-hydroxydodec-8(E)-enoic acid so obtained gave (VI). The IR, PMR, and mass spectra of (VI) are presented.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00580448
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