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  • 1
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    International journal of health care quality assurance 9 (1996), S. 10-17 
    ISSN: 0952-6862
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Medicine , Economics
    Notes: Points out some important issues that must be dealt with when developing microcomputer-based QA systems for health care. While no single solution to the problems associated with quality assurance (QA) system development exists, the first step towards an efficient and effective approach is problem identification and commitment to developing a strategy which addresses the issues discussed in this paper. Examines potential solution alternatives and associated pitfalls, and gives an example of designing a QA system, including a database management system with suggestions for spreadsheet templates.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    International journal of quality & reliability management 13 (1996), S. 73-83 
    ISSN: 0265-671X
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Expert systems (ES) are designed to support and replicate management tasks and decision making characterized by experience and expertise. These commodities are becoming increasingly limited as organizations flatten their management structure. Effective identification and evaluation of domains appropriate for ES-based solutions are critical to their successful development and implementation. Presents a comprehensive model for ES domain identification and evaluation that includes an emphasis on total quality management (TQM) and can be used as a project management tool. The TQM matrix evaluation model proposed facilitates qualitative and quantitative assessment of ES domains and can provide for dynamic evaluation, feedback and continuous quality management over the entire project life cycle. Tests the TQM matrix evaluation model by applying it to a real business problem and presents and discusses the results.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    Business process management journal 3 (1997), S. 9-16 
    ISSN: 1355-2503
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Business process re-engineering requires revolutionary, innovative changes to business processes in an organization in order to achieve major and dramatic improvements in the critical success factors. To accomplish these goals new technologies need to be investigated and adopted. Organizations are experiencing paradigm shifting that at times is bordering on paradigm pioneering. For a dramatic, innovative re-engineering effort to be successfully implemented, change management is essential. While information technology has great potential for providing added value to products and services, business executives are frustrated because business processes and information technology are not synchronized. The inflexibility of older information systems and information technology (IS/IT) constrained growth and competitiveness and resulted in the development of substitute processes to circumvent these constraints. While continuous improvement is the slow, steady and continuous effort to improve products and/or services, it may not be the best course for some organizations. Ideally, both are needed to maintain a competitive advantage. Provides some suggestions on how an organization may approach these processes and presents a case that demonstrates how one organization dealt with these issues.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 6 (1986), S. 339-346 
    ISSN: 0886-1544
    Keywords: axonal transport ; human nerve ; video-enhancement ; digital image processing ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The mechanism by which organelles are transported bidirectionally in axoplasm is still unknown; however, evidence of a key role for microtubules in many nonmammalian models has been established. We have observed common or shared tracks within the axoplasm of human nerves along which multiple organelles of varying size and shape are bidirectionally transported. Organelles traveling anterogradely and retrogradely were visualized by video-enhanced differential interference contrast optics and analyzed with the aid of computer-image-processing techniques.Speeds of translocating organelles were determined at eight to 16 translocation points along a path or “track.” Each translocation speed was plotted against its corresponding position on the track to develop a “speed/position diagram.” Regardless of mean organelle speed or direction of motion, organelles sharing a common track exhibited similar patterns of “speeding up” and “slowing down” relative to position along the track. Speed position data for organelles translocating the local axonal region of a common track showed no unique patterns (not different from a uniform distribution, p 〈 0.05). The unique speed/position patterns exhibited by common tracks were not necessarily related to the patterns of other tracks in the immediate vicinity (distance between tracks of 〈 0.50 μm). These findings suggest that (1) there are “common tracks” shared by organelles moving retrogradely and anterogradely; (2) both the organelles and the “track” associated with its translocation play a role in the resultant motion of that organelle; (3) the influence exerted by a common track on the motion of an organelle results in a pattern of speed changes related to position along the track.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0886-1544
    Keywords: video microscopy ; axonal transport ; computer motion analysis ; giant axon ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Moving intra-axonal organelles demonstrate frequent variations in speed when viewed over several seconds. To evaluate these and other motion variations, a long-term analysis of organelle motion in isolated axoplasm of Myxicola infundibulum was carried out using differential interference contrast optics and analog and digital image enhancement techniques. Motion characteristics of individual organelles were analyzed for periods of up to 58 minutes. Three principle observations on organelle motion were made: (1) Classes of organelles of the same size demonstrated a 5- to 25-fold variation of speed, with the slowest speeds occurring most frequently; (2) organelle speeds over individual translocations (motion without stopping) are inversely proportional to their size, but the speeds calculated for the long-term analysis of organelle motion (total distance travelled/total observation time, including pauses) did not reflect this observation; and (3) organelles displayed variable trip lengths, durations, mean speeds, and pause durations, and the relationships between these variations showed no repetitive patterns. In contrast to reported observations of uniform velocities of organelles moving on isolated microtubule preparations, these observations suggest that a variety of factors must play a role in organelle translocation in Myxicola axoplasm.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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