Publication Date:
2015-07-09
Description:
Article Skeletal muscle stem cells (satellite cells) express different levels of a critical transcriptional regulator Pax7. Here, the authors show that miR-431 regulates Pax7 levels in satellite cells of the developing and regenerating muscle, and that increased miR-431expression in these cells alleviates symptoms of muscular dystrophy in mice. Nature Communications doi: 10.1038/ncomms8713 Authors: Rimao Wu, Hu Li, Lili Zhai, Xiaoting Zou, Jiao Meng, Ran Zhong, Changyin Li, Haixia Wang, Yong Zhang, Dahai Zhu
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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