Publikationsdatum:
2017-09-20
Beschreibung:
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance Nature Communications, Published online: 19 September 2017; doi:10.1038/s41467-017-00452-4 Resistance to BRAFV600E inhibitors often occurs in melanoma patients. Here, the authors describe a potential mechanism of acquired drug resistance mediated by tumor-associated B cells-derived IGF-1.
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
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