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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 247 (1974), S. 461-462 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Here we report immunoelectron microscopy observation of A antigen on human normoblasts using peroxidase-labelled antibodies which allow detection of surface antigens on separated cells. A preliminary report has appeared6 in which A antigen was detected by this method on circulating normal ...
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2019
    Description: Abstract Modern measurement campaigns of man‐made radiofrequency (RF) noise have reported results from fixed locations which are assumed to be representative of the surroundings. Models derived from these measurements include parameters to express the variability in time and in space over very large distances (i.e. differences between cities). Despite the rapidly evolving mixture of noise sources, especially in modern urban environments, spatial variation of RF noise power at the scale of streets and blocks is essentially unknown in the VHF and UHF bands. Using a portable calibrated noise measurement system of our design, RF noise was recorded over a 1 MHz bandwidth for frequencies of 142.0, 246.5 and 972 MHz. Noise surveys were conducted during daytime working hours in several different neighborhoods within Boston, Massachusetts, USA, with each survey transiting a fixed, several kilometer long route, repeated twice to enable separation of temporal from spatial variability. Significant and spatially repeatable variations in median power, peak power, and voltage deviation were observed over distances of tens to hundreds of meters, dependent upon the measurement frequency. The observed spatial patterns of median and peak power appear to be repeatable on time scales of hours to weeks, and likely beyond, suggesting that these noise patterns are persistent features of the urban environment.
    Print ISSN: 0048-6604
    Electronic ISSN: 1944-799X
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 3
    Publication Date: 2012-02-29
    Description: Many plants monitor day-length changes throughout the year and use the information to precisely regulate the timing of seasonal flowering for maximum reproductive success. In Arabidopsis thaliana, transcriptional regulation of the CONSTANS (CO) gene and posttranslational regulation of CO protein are crucial mechanisms for proper day-length measurement in photoperiodic flowering. Currently, the CYCLING DOF FACTOR proteins are the only transcription factors known to directly regulate CO gene expression, and the mechanisms that directly activate CO transcription have remained unknown. Here we report the identification of four CO transcriptional activators, named FLOWERING BHLH 1 (FBH1), FBH2, FBH3, and FBH4. All FBH proteins are related basic helix–loop–helix-type transcription factors that preferentially bind to the E-box cis-elements in the CO promoter. Overexpression of all FBH genes drastically elevated CO levels and caused early flowering regardless of photoperiod, whereas CO levels were reduced in the fbh quadruple mutants. In addition, FBH1 is expressed in the vascular tissue and bound near the transcription start site of the CO promoter in vivo. Furthermore, FBH homologs in poplar and rice induced CO expression in Arabidopsis. These results indicate that FBH proteins positively regulate CO transcription for photoperiodic flowering and that this mechanism may be conserved in diverse plant species. Our results suggest that the diurnal CO expression pattern is generated by a concert of redundant functions of positive and negative transcriptional regulators.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1990-06-15
    Description: The bacterial photosynthetic reaction center (RC) is a pigmented intrinsic membrane protein that performs the primary charge separation event of photosynthesis, thereby converting light to chemical energy. The RC pigments are bound primarily by two homologous peptides, the L and M subunits, each containing five transmembrane helices. These alpha helices and pigments are arranged in an approximate C2 symmetry and form two possible electron transfer pathways. Only one of these pathways is actually used. In an attempt to identify nonhomologous residues that are responsible for functional differences between the two branches, homologous helical regions that interact extensively with the pigments were genetically symmetrized (that is, exchanged). For example, replacement of the fourth transmembrane helix (D helix) in the M subunit with the homologous helix from the L subunit yields photosynthetically inactive RCs lacking a critical photoactive pigment. Photosynthetic revertants have been isolated in which single amino acid substitutions (intragenic suppressors) compensate for this partial symmetrization.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Robles, S J -- Breton, J -- Youvan, D C -- RIGM42645A/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1990 Jun 15;248(4961):1402-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Graduate Program in Applied Biological Sciences, Massachusetts Institute of Technology, Cambridge 02139.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2192455" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; *Bacterial Proteins/genetics ; Cloning, Molecular ; Electron Transport ; Macromolecular Substances ; Molecular Sequence Data ; Molecular Structure ; Mutation ; Photosynthesis ; Photosynthetic Reaction Center Complex Proteins ; Protein Conformation ; Rhodopseudomonas/analysis/genetics/growth & development ; Spectrophotometry
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2012-10-24
    Description: Environmental Science & Technology DOI: 10.1021/es302041k
    Print ISSN: 0013-936X
    Electronic ISSN: 1520-5851
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
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  • 6
    Publication Date: 2015-02-27
    Description: Interpretation of ice core trace gas records depends on an accurate understanding of the processes that smooth the atmospheric signal in the firn. Much work has been done to understand the processes affecting air transport in the open pores of the firn, but a paucity of data from air trapped in bubbles in the firn-ice transition region has limited the ability to constrain the effect of bubble closure processes. Here we present high-resolution measurements of firn density, methane concentrations, nitrogen isotopes, and total air content that show layering in the firn-ice transition region at the WAIS Divide ice core site. Using the notion that bubble trapping is a stochastic process, we derive a new parameterization for closed porosity that incorporates the effects of layering in a steady-state firn modeling approach. We include the process of bubble trapping into an open-porosity firn air transport model, and obtain a good fit to the firn core data. We find that layering broadens the depth range over which bubbles are trapped, widens the gas-age distribution of air in closed bubbles, reduces the mean gas-age of air in closed bubbles, and introduces stratigraphic irregularities in the gas-age scale that have a peak-to-peak variability of ~10 years at WAIS-Divide. For a more complete understanding of gas occlusion and its impact on ice core records we suggest that this experiment be repeated at sites climatically different from WAIS Divide, for example on the East Antarctic plateau.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 7
    Publication Date: 1972-10-01
    Description: In a case of refractory anemia with an excess of myeloblasts in the bone marrow and with thrombocytopenia, examinations of the blood cells under the electron microscope have revealed nucleated cells similar in size to small lymphocytes. Some of these lymphocytelike cells have scanty cytoplasm identical to that of giant platelets present in the blood, which are pathologic in view of their highly developed system of membranes. In the perinuclear space and in short segments of the smooth endoplasmic reticulum, these blood micromegakaryocytes exhibit a peroxidase activity that is identical to that of mature megakaryocytes of normal bone marrow. They also spread over glass like giant platelets. In the past these nucleated cells could well have been confused with atypical lymphocytes, because on stained slides their atypical appearance makes identification difficult.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 8
    Publication Date: 1974-02-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 9
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 10359-10363 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Total scattering cross sections for low-energy collisions of C60 fullerene with alkali ions are theoretically estimated using an accurate spherical potential approximation. These cross sections show the relevance of polarization effects. Our results indicate a way in which collisional experimental methods could be used to measure the high polarizabilities of C60 and other fullerenes. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 109 (1998), S. 3573-3579 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We introduce a secular semiempirical model of the Pariser–Parr–Pople type to reproduce the electronic structure and polarizability of the C60 fullerene. The model is then used to simulate the response of this molecule to an electric charge and estimate its polarization energy. By expressing the charge potential at the C60-cage surface as a multipole expansion, an analytical form is obtained for the polarization energy. Application of these results to endo- and exohedral complexes of alkali ions gives data in rather good agreement with recent ab initio calculations [Hira and Ray, Phys. Rev. A 52, 141 (1995)]. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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