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  • 1
    Electronic Resource
    Electronic Resource
    DNA Recognition by Proteins with the Helix-Turn-Helix Motif (1990)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biochemistry 59 (1990), S. 933-969 
    Details
    ISSN: 0066-4154
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Chemistry and Pharmacology , Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.bi.59.070190.004441
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  • 2
    Electronic Resource
    Electronic Resource
    Tomato bushy stunt virus at 2.9 Å resolution (1978)
    [s.l.] : Nature Publishing Group
    Nature 276 (1978), S. 368-373 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The polypeptide chain of a TBSV subunit folds into two domains, connected by a hinge, and a flexibly-linked N-terminal arm. Sixty of the 180 N-terminal arms inter-digitate in groups of three, in an unexpected mode of protein association. The remaining 120 arms are not uniquely positioned with ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/276368a0
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  • 3
    Electronic Resource
    Electronic Resource
    A point-focusing camera for single-crystal diffraction (1968)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 1 (1968), S. 84-90 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Bent-glass mirrors can be used to produce a narrow, highly collimated X-ray beam, particularly suitable for photographing diffraction patterns from crystals with very large unit cells (i.e., several hundred Å to a side). A camera is described that employs double-mirror focusing optics with a precession apparatus. A comparison of optical reflection and simple collimation shows that for high resolving power, focusing devices are very much superior to pinhole collimators. The reduction of background is especially noteworthy. Use of this camera has permitted the collection of accurate three-dimensional data from crystals of tomato bushy stunt virus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889868005054
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  • 4
    Electronic Resource
    Electronic Resource
    A system for collection and on-line integration of X-ray diffraction data from a multiwire area detector (1987)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 20 (1987), S. 235-242 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: A system for collecting and measuring X-ray diffraction data from protein crystals has been developed for a multiwire area detector. Computer programs run concurrently on two microcomputers, which collect and reduce detector data to integrated intensities. The self-contained system consists of an X-ray area detector, a rotation/oscillation camera, and two microcomputers connected by a high-speed Ethernet network. One microcomputer is dedicated to operation of the detector, control of the camera, and storage of the raw data. The second microcomputer automatically integrates the data as they are collected and allows the user to monitor the quality of data as they are processed. The integration programs are written in Fortran 77 and have been designed to be portable. Additional programs for crystal alignment, detector and camera control, and graphics are written in the C programming language. A description of the system, some characteristics of the detector, and the results of data collection are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889887086783
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  • 5
    Electronic Resource
    Electronic Resource
    The oscillation method for crystals with very large unit cells (1979)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 35 (1979), S. 901-911 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The processing of data collected by oscillation photography from crystals with very large unit cells (average cell constant ∼ 250 Å) requires important modifications of standard methods. In particular, it is often necessary to correct partially recorded intensities to their fully recorded equivalents. A procedure is described for accurate determination of relevant parameters (crystal setting, cell constants). It relies on the redundancy present in most data-collection strategies, which yields fully recorded, symmetry-related counterparts of a number of partially recorded reflections. A detailed description of one example (tomato bushy stunt virus) is presented, with complete intensity statistics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739479002035
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  • 6
    Electronic Resource
    Electronic Resource
    A simulated annealing approach to the search problem of protein crystallography (1989)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 45 (1989), S. 337-342 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: With the growing availability of computer power it has become routine to perform exhaustive multi-dimensional searches in protein crystallography. Specifically, in cases where homologous or partially homologous structures are available, the initial interpretation of poor electron density maps is done by performing computer-intensive rotational and translational searches in real space. Often such calculations of the best fit between structure and map cannot even be attempted owing to the vast computing effort involved (years of MicroVAX II time). Here, the combinatorial optimization method, simulated annealing, is shown to reduce substantially the computing effort involved and also to permit computations that are beyond the reach of current algorithms. This is illustrated with practical examples involving the structure determinations of the human histo-compatibility antigen HLA-A2 and an influenza virus hemagglutinin-sialic acid complex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S010876738801476X
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  • 7
    Electronic Resource
    Electronic Resource
    Structure of the represser–operator complex of bacteriophage 434 (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 846-852 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The crystal structure of a specific complex between the DNA-binding domain of phage 434 represser and a synthetic 434 operator DNA shows interactions that determine sequence-dependent affinity. The represser recognizes its operators by its complementarity to a particular DNA conformation as ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/326846a0
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  • 8
    Electronic Resource
    Electronic Resource
    Structure of the expanded state of tomato bushy stunt virus (1982)
    [s.l.] : Nature Publishing Group
    Nature 297 (1982), S. 563-568 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The full three-dimensional structure determination of tomato bushy stunt virus has shown how its protein subunit can accommodate to different packing environments in the viral coat and how the size of the particle is nonetheless determined without ambiguity. Reversible, cooperative expansion of the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/297563a0
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  • 9
    Electronic Resource
    Electronic Resource
    Molecular Organization in the Sarcoplasmic Reticulum Membrane studied by X-ray Diffraction (1973)
    [s.l.] : Nature Publishing Group
    Nature 244 (1973), S. 555-558 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Orientated preparations of rabbit sarcoplasmic reticulum vesicles give X-ray diffraction maxima to a resolution of 16 Å. The calculated electron density profile shows that protein is distributed very asymmetrically in the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/244555a0
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  • 10
    Electronic Resource
    Electronic Resource
    Tomato bushy stunt virus at 5.5-Å resolution (1977)
    [s.l.] : Nature Publishing Group
    Nature 265 (1977), S. 509-513 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The coat of tomato bushy stunt virus is built from protein subunits having rigid domains connected by a flexible hinge. Two states of the hinge are present in the T = 3 icosahedral structure. Each subunit has a binding site for RNA on its inner ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/265509a0
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