ISSN:
1573-3904
Keywords:
nonradioactive labeling
;
peptide nucleic acids
;
PNA
;
PNA-peptide chimera
;
tag-peptide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The preparation of peptide nucleic acids (PNA)carrying a c-myc tag-peptide sequence isdescribed. These PNA-peptide chimeras have higheraffinity to complementary DNA than unmodifiedoligonucleotides. Moreover, they can be used asnonradioactive probes with sensitivity similar toother nonradioactive methods.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1008933416669
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