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  • 1
    Publication Date: 2020-11-23
    Description: Different pain types may be encoded in different brain circuits. Here, we examine similarities and differences in brain processing of visceral and somatic pain. We analyze data from seven fMRI studies (N = 165) and five types of pain and discomfort (esophageal, gastric, and rectal distension, cutaneous thermal stimulation, and vulvar pressure) to establish and validate generalizable pain representations. We first evaluate an established multivariate brain measure, the Neurologic Pain Signature (NPS), as a common nociceptive pain system across pain types. Then, we develop a multivariate classifier to distinguish visceral from somatic pain. The NPS responds robustly in 98% of participants across pain types, correlates with perceived intensity of visceral pain and discomfort, and shows specificity to pain when compared with cognitive and affective conditions from twelve additional studies (N = 180). Pre-defined signatures for non-pain negative affect do not respond to visceral pain. The visceral versus the somatic classifier reliably distinguishes somatic (thermal) from visceral (rectal) stimulation in both cross-validation and independent cohorts. Other pain types reflect mixtures of somatic and visceral patterns. These results validate the NPS as measuring a common core nociceptive pain system across pain types, and provide a new classifier for visceral versus somatic pain.
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 2
    Publication Date: 2024-03-23
    Description: Sexual health in Flanders describes the results of the first representative population-based study on this topic in Flanders (the Northern, Dutch-speaking part of Belgium). A research team of psychologists, sexologists, sociologists and medical doctors, affiliated with Ghent University, KU Leuven and Ghent University Hospital collaborated on this research project that aimed to explore various aspects of sexual behavior and sexual health in men and women living in Flanders. Apart from providing in reliable, valid, descriptive scientific data, this study offers important information on which a more targeted policy to promote sexual health can be developed. This reference work is based on a survey in which 1832 Flemish men and women – aged 14 to 80 years old – participated and that covered various aspects of sexual health. The focus is not only on sexual experiences and practices; attention is also paid to the relational and social context in which these experiences occur. In addition, a number of chapters elaborate on the sexual start (the first sexual experiences), reproductive health, sexual dysfunctions, cross-border sexual behavior, and profiles of sexual health. The detailed description of the methodology that was used, allows the reader to evaluate the accuracy of the many tables, figures and numbers that are presented. In short, Sexual health in Flanders is an essential reference work for anyone with an interest in a reliable, detailed and scientific image of a broad range of aspects of sexual health in Flanders.
    Keywords: sexual experience ; sexual health ; flanders ; thema EDItEUR::1 Place qualifiers::1D Europe::1DD Western Europe::1DDB Belgium ; thema EDItEUR::2 Language qualifiers::2A Indo-European languages::2AC Germanic and Scandinavian languages::2ACD Dutch ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MR 21st century, c 2000 to c 2100 ; thema EDItEUR::5 Interest qualifiers::5A Interest age / level::5AX For adult emergent readers ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology ; thema EDItEUR::J Society and Social Sciences::JM Psychology ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBS Medical sociology
    Language: Dutch
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