Publication Date:
2014-08-13
Description:
Article Unlike most processive motor proteins, the stepping motion of cytoplasmic dynein’s two linked motor domains is not precisely coordinated. Cleary et al. show that the ATPase activity of just one head is required for processive movement, and that tension on the linker gates the release of the motor from microtubules. Nature Communications doi: 10.1038/ncomms5587 Authors: Frank B. Cleary, Mark A. Dewitt, Thomas Bilyard, Zaw Min Htet, Vladislav Belyy, Danna D. Chan, Amy Y. Chang, Ahmet Yildiz
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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