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  • 1
    Publication Date: 2004-01-01
    Print ISSN: 0008-543X
    Electronic ISSN: 1097-0142
    Topics: Biology , Medicine
    Published by Wiley on behalf of American Cancer Society.
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 28 (1979), S. 93-97 
    ISSN: 1432-0827
    Keywords: Osteomalacia ; Anticonvulsant drugs ; Epileptics ; Calcification front ; Osteoclasts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary In 31 epileptics, most of whom had been on anticonvulsive drugs for decades, the amount of osteoid—active and inactive—and the osteoclast activity were measured in iliac crest biopsies and compared with the same variables from a control group. Although falling within normal limits, the amount of osteoid, in particular the inactive osteoid, was significantly increased in the epileptics. The osteoclast activity was also significantly increased in the epileptics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 36 (1984), S. 354-356 
    ISSN: 1432-0827
    Keywords: Bone mineral ; Menarche ; Menopause
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The bone mineral content of the forearms was measured in 395 women, aged 49, and correlated with menarche, menopause, parity, lactation, contraceptives, diet, smoking, and physical activity. Late menarche and early menopause were associated with a lower than average bone mineral content whereas the life-style parameters were not.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 52 (1993), S. 212-215 
    ISSN: 1432-0827
    Keywords: Bone mineral density ; Weightlifters ; DXA ; Physical activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The effect of intense physical training on the bone mineral content (BMC) and soft tissue composition, and the development of these values after cessation of the active career, was studied in 40 nationally or internationally ranked male weight lifters. Nineteen were active and 21 had retired from competition sports. Fifty-two age- and sexmatched nonweight lifters served as controls. The bone mineral density (BMD) in total body, spine, hip, and proximal tibial metaphysis was measured with a Lunar Dual-energy X-ray absorptiometry (DXA) apparatus and the BMD of the distal forearm was measured with single photon absorptiometry (SPA). Seventeen of the lifters had been measured earlier with SPA in the forearm and 23 in the tibial condyle during their active career in 1975. The BMD was significantly higher in the weight lifters compared with the controls (10% in the total body P〈0.001, 12% in the trochanteric region P〈0.001, and 13% in the lumbar spine P〈0.001). All measured regions except the head showed significant higher bone mass in the weight lifters compared with the controls. In older lifters, the difference from the controls seemed to increase in total body and lumbar vertebrae (BMD), but remained unchanged in the hip. Significant correlation was found between the SPA measurements in 1975 and the corresponding measurements 15 years later in both the forearm (r=0.51, P〈0.05 at the 1-cm level and r=0.87, P〈0.001 at the 6-cm level) and in the tibial condyle (r=0.61, P〈0.01). There was no difference in BMD for any region between active and retired weight lifters that was not explained by difference in age. The weight lifters were on average 5 cm shorter but of the same weight as the controls. In the weight lifters, the body mass index (BMI) was increased as was the lean body mass, but not the fat content.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 52 (1993), S. 348-353 
    ISSN: 1432-0827
    Keywords: Bone mineral ; Fractures ; Body weight ; Screening
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary This is a follow-up of a previous study on the predictive power of bone mineral measurements; two more observation years have been added. A group of women (n=1076) had their forearm bone mineral content (BMC) measured from 1970–1976. All fractures that occurred in 1975–1987 (13 years) were recorded. Four hundred sixty-nine fragility fractures occurred during the collection period. Again, it was found that BMC at the distal end of the forearm is a good predictor of future fracture before the age of 70. The measurement at the proximal site (forearm shafts), however, in contrast to our previous study, has a capacity of predicting fracture also in the age group 70–80. BMC measurements were good predictors of vertebral crush fractures and trochanteric hip fracture but lesser predictors of fractures of the distal end of the forearm. In age groups 40–70, BMC was a stronger predictor of fracture than age, and the risk associated with a 1 SD decrease of BMC 6 was 3.2 for a hip fracture as compared with those without any fragility fracture, even when adjusted for age. In addition to BMC, low body weight was a fracture predictor. Body weight 5 kg below age-adjusted mean increased the risk of a trochanteric hip fracture by 30%. The data are used in hypothetical calculations of the effects of screening.
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  • 6
    ISSN: 1432-0827
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary In order to explain the higher prevalence of fractures in urban compared with rural areas, 782 residents in the city of Malmö, Sweden and 486 inhabitants from the nearby rural municipality of Sjöbo were invited to participate in an sex- and age-matched cross-sectional study on life-style differences; 73 and 80% respectively responded. Responders answered a questionnaire on medical and social background and were interviewed on past and present physical activity. The men and women of the rural area were found to be significantly more active physically at work and during spare time. Housing was larger in the rural area. For women, these differences are decreasing in the younger age groups. Bone mass was found to be correlated to heavier work load for men. Other life-style variable such as dairy calcium intake, coffee drinking, estrogen medication, and morbidity, could not explain this difference. Higher prevalence of fractures in the city could therefore be explained by physicall less active life-style.
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