Publication Date:
2017-09-20
Description:
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance Nature Communications, Published online: 19 September 2017; doi:10.1038/s41467-017-00452-4 Resistance to BRAFV600E inhibitors often occurs in melanoma patients. Here, the authors describe a potential mechanism of acquired drug resistance mediated by tumor-associated B cells-derived IGF-1.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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