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  • 1
    Keywords: Human physiology. ; Immune system. ; Cellular signal transduction. ; Respiratory organs. ; Physiology. ; Diseases. ; Human Physiology. ; Immune Cell Signalling. ; Respiratory Physiology. ; Diseases.
    Description / Table of Contents: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Targeting molecular and cellular mechanisms in asthma.-Chapter 3. Various cellular and molecular axis involved in the pathogenesis of asthma -- Chapter 4. Targeting molecular and cellular mechanisms in steroid resistant asthma -- Chapter 5. Targeting molecular and cellular mechanisms in chronic obstructive pulmonary disease -- Chapter 6. Probing the cellular and molecular mechanisms underlying in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD) -- Chapter 7. Chronic obstructive pulmonary disease: Molecular basis of pathogenesis and targeted therapeutic approaches -- Chapter 8. Exploring the ‘dormancy-activation switch’ in the tumour microenvironment for metastatic lung cancer: The possible role of microRNA -- Chapter 9. Therapeutic strategies targeting signalling pathways in lung cancer -- Chapter 10. Modulation of signalling pathways by immunotherapeutics in lung cancer -- Chapter 11. Underpinning the Cellular and Molecular Mechanisms with Nanotheronstics for Lung Cancer -- Chapter 12. Targeting molecular and cellular mechanisms in Idiopathic Pulmonary Fibrosis.-Chapter 13. A refined approach to target the molecular and cellular mechanisms in pulmonary fibrosis.-Chapter 14. Targeting molecular and cellular mechanisms in tuberculosis -- Chapter 15. Cellular and Molecular Mechanisms of Repurposed antidiabetic drug as adjunctive treatment for tuberculosis -- Chapter 16. Targeting host and bacterial signaling pathways in tuberculosis: An effective strategy for the development of novel anti-tubercular therapies -- Chapter 17. Targeting molecular and cellular mechanisms in pulmonary hypertension -- Chapter 18. Targeting molecular and cellular mechanisms in pulmonary arterial hypertension -- Chapter 19. Potential cellular targets associated with the signaling and therapeutics of the pulmonary hypertension -- Chapter 20. Targeting molecular and cellular mechanisms in influenza A virus infections -- Chapter 21. Understanding the Biology of Non-typeable Haemophilus influenzae in Chronic Obstructive Pulmonary Disease through the Lens of Genomics -- Chapter 22. Targeting molecular and cellular mechanisms in rhinovirus infection -- Chapter 23. Targeting molecular and cellular mechanisms in respiratory syncytial virus (RSV) infection -- Chapter 24. Targeting molecular and cellular mechanisms SARS-CoV2 novel corona (COVID-19) virus infection -- Chapter 25. Underpinning the rudimentary mechanisms involved in the pathogenesis of SARS-CoV2 (COVID-19) in human lung cells -- Chapter 26. Targeting molecular and cellular mechanisms in SARS-CoV2 novel corona (COVID-19) virus infection -- Chapter 27. Special features of human lung ACE2 sensitivity to SARS CoV-2 spike glycoprotein -- Chapter 28. Implications of Phosphoinositide 3-kinase (PI3K) Signalling in cellular and molecular mechanisms of respiratory diseases -- Chapter 29. The role of the cholinergic system in lung diseases -- Chapter 30. The Nrf2-Keap1 signaling pathway in lung cancer -- Chapter 31. Role of Toll like receptor (LTR) in molecular and cellular mechanism of respiratory diseases -- Chapter 32. Biomarkers of Oxidative Stress -- Chapter 33. Targeting chronic lung diseases using advanced drug delivery systems -- Chapter 34. Plant based chemical moieties targeting cellular signalling pathways in chronic lung diseases -- Chapter 35. Role of phytoconstituents in targeting cytokines for managing pathophysiology of lung diseases -- Chapter 36. Targeting Cellular Signaling Pathways in Lung Cancer and Role of Phytochemicals as Novel Therapeutic Approach -- Chapter 37. Natural compounds targeting major signalling pathways in lung cancer -- Chapter 38. Drug delivery in respiratory diseases: Current opportunities, Molecular and cellular mechanism, and Future challenges -- Chapter 39. Future prospects and challenges in targeting cellular and molecular mechanisms in respiratory diseases.
    Abstract: The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
    Type of Medium: Online Resource
    Pages: XIV, 926 p. 149 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813368279
    DDC: 612
    Language: English
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  • 2
    Keywords: Microbial populations. ; Inflammation. ; Respiratory organs. ; Physiology. ; Cancer. ; Microbial Communities. ; Inflammation. ; Respiratory Physiology. ; Cancer Biology.
    Description / Table of Contents: Introduction to Lung Diseases -- Introduction to Microbiome -- Role of Microbiome in Inflammation -- The interplay of microbiome, inflammation, and immunity in inflammatory lung diseases -- Microbiome in Asthma -- Microbiome in Chronic Obstructive Pulmonary Disease -- Microbiome in Asthma-COPD Overlap syndrome (ACO) -- Microbiome in ARDS (Acute Respiratory Distress Syndrome) -- Role of brain-gut- microbiome axis in Depression co-morbid with COPD or Asthma -- Microbiome in Lung Cancer -- Microbiome in Pulmonary Tuberculosis -- Lung Microbiome: Friend or Foe of Mycobacterium tuberculosis -- Microbiome in Idiopathic Pulmonary Fibrosis. Microbiome in SARS-Cov2 (Covid-19) -- Status of the microbiome in SARS-Cov2 (Covid-19) -- Microbiome in Influenza-A Virus Infection -- Microbiome in Upper Respiratory Tract Infection (URTI) -- Challenges in understanding the lung microbiota -- Microbiome in Inflammatory Lung Diseases: Challenges and Future Prospects -- Microbiota targeted via nanotechnology for lung cancer therapy: Challenges and future perspectives.
    Abstract: This book reviews the role of the lung microbiome in the development and progression of lung diseases. It deals with the role of microbiota dysbiosis in influencing host defense and immunity leading to resistance, colonization, and disease exacerbation. The book delineates the complex interaction between pathogen and lung residual microbiota during disease conditions. It further highlights the potential role of lung microbiota as the key modulator of lung carcinogenesis and immune response against cancer cells. Lastly, it reviews technological developments for unraveling the lung microbiome that profoundly impacts clinical diagnostics. This book is an essential resource for the scientists working in pulmonary diseases, pharmaceutical & clinical sciences, and pulmonary clinicians.
    Type of Medium: Online Resource
    Pages: XIV, 377 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689574
    DDC: 579.1788
    Language: English
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  • 3
    Keywords: Pharmacology. ; Epigenetics. ; Respiratory organs. ; Physiology. ; Pharmacology. ; Epigenetics. ; Respiratory Physiology.
    Description / Table of Contents: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Introduction to Epigenetics -- Chapter 3._Epigenetic mechanisms in Inflammation -- Chapter 4. Epigenetic regulator of inflammatory gene expression -- Chapter 5. Epigenetics of Asthma -- Chapter 6_. Epigenetic optimization in chronic obstructive pulmonary disease (COPD -- Chapter 7. Epigenetics of Lung Cancer -- Chapter 8. Epigenetics of Pulmonary Tuberculosis -- Chapter 9. Epigenetics of Idiopathic Pulmonary Fibrosis -- Chapter 10. Epigenetics of influenza-A virus infection -- Chapter 11. Epigenetics of rhinovirus -- Chapter 12. Epigenetics of SARS-Cov2 (Covid-19) -- Chapter 13. Epigenetics of Haemophilus Influenzae -- Chapter 14. Future Prospects and Challenges -- Chapter 15. Targeting epigenetics in pulmonary arterial hypertension.
    Abstract: This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.
    Type of Medium: Online Resource
    Pages: XV, 266 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819947805
    DDC: 615
    Language: English
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