Publication Date:
1980-11-28
Description:
Conditioned medium derived from organ or cell cultures prepared from 19- to 21-day fetal rat calvaria stimulated the incorporation of [3H]proline collagen and of [3H]thymidine into DNA in organ cultures of the same tissue. Addition of cortisol enhanced the effect on collagen but not on DNA synthesis. These effects appeared to be due to a nondialyzable and heat-stable growth factor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Canalis, E -- Peck, W A -- Raisz, L G -- AM-18063/AM/NIADDK NIH HHS/ -- AM-19855/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1980 Nov 28;210(4473):1021-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7434011" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
*Bone Development
;
Bone and Bones/*physiology
;
Collagen/*biosynthesis
;
Culture Techniques
;
DNA/biosynthesis
;
Growth Substances/isolation & purification/*physiology
;
Hydrocortisone/pharmacology
;
Rats
;
Skull
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
