Publication Date:
1981-06-12
Description:
In animals with hippocampal damage, the signaled administration of reward is sufficient to induce the sort of behavioral sterotypy and locomotion that heretofore has been observed only after drug administration. Haloperidol returns these behaviors to normal. The interaction of the hippocampus with reward helps to explain many well-known characteristics of animals with lesions in the hippocampus and may have relevance for catecholamine-based clinical disorders.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Devenport, L D -- Devenport, J A -- Holloway, F A -- New York, N.Y. -- Science. 1981 Jun 12;212(4500):1288-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7195073" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Dextroamphetamine/pharmacology
;
Food Deprivation
;
Hippocampus/drug effects/*physiology
;
Humans
;
Locomotion/drug effects
;
Rats
;
*Stereotyped Behavior/drug effects
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
