Publication Date:
1981-05-22
Description:
Three syngeneic carcinomas from two species shed plasma membrane vesicles when cultured in vitro or grown in the ascites tumor form in vivo. Shed vesicles carry procoagulant activity that can account for the activation of the clotting system and the fibrin deposition associated with these and many other types of malignancy in animals and man.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dvorak, H F -- Quay, S C -- Orenstein, N S -- Dvorak, A M -- Hahn, P -- Bitzer, A M -- Carvalho, A C -- CA 28471/CA/NCI NIH HHS/ -- CA 28834/CA/NCI NIH HHS/ -- HL 23591-2/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1981 May 22;212(4497):923-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7195067" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Ascitic Fluid/metabolism
;
*Blood Coagulation
;
Blood Coagulation Factors/*metabolism
;
Cell Membrane/metabolism
;
Fibrin/metabolism
;
Liver Neoplasms, Experimental/*physiopathology
;
Mammary Neoplasms, Experimental/*physiopathology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
