Publication Date:
2017-04-11
Description:
Structural and functional analysis of the human POT1-TPP1 telomeric complex Nature Communications, Published online: 10 April 2017; doi:10.1038/ncomms14928 POT1 and TTP1 are part of the shelterin complex that caps and stabilizes the ends of telomeres. Here the authors present a structural analysis of the human POT1-TTP1 complex, shedding light on how it assembles and how cancer-associated mutations impact its assembly and function.
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics