ISSN:
1365-2761
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
,
Medicine
Notes:
Abstract. An extract vaccine against Vibrio anguillarum was compared with other vaccine preparations when administered to rainbow trout intraperitoneally or orally on food. Intraperitoneal vaccination resulted in virtually 100% protection within two weeks whereas oral vaccination gave a maximum protection of 50–70% after eight weeks. When administered intraperitoneally the extract performed better than formalin killed cells but when administered orally formalin killed cells were better. The addition of alum as adjuvant enhanced the response to antigen administered by both routes. Serum agglutinin litres after oral vaccination were low and variable but after intraperitoneal injection they reached a consistent peak of 64. As the response to oral vaccination was so low it was not possible to relate agglutinin titre to protection in a quantitative relationship.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2761.1983.tb00060.x
