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The CBP co-activator is a histone acetyltransferase (1996)

Bannister, Andrew J. ; Kouzarides, Tony

[s.l.] : Nature Publishing Group

Nature 384 (1996), S. 641-643

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] To monitor the HAT activity associated with CBP in vivo, we developed an immunoprecipitation-HAT (IP-HAT) assay. Immunoprecipitaiton of CBP from whole-cell extracts (and nuclear extracts; data not shown) brings down an associated acetylase activity that is specific for histones (Fig. 1). Antibodies ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/384641a0

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