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Research Highlights (2007)

[s.l.] : Nature Publishing Group

Nature structural & molecular biology 14 (2007), S. 688-688

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ISSN: 1545-9985

Source: Nature Archives 1869 - 2009

Topics: Biology , Medicine

Notes: [Auszug] PI3K polar patch Phosphoinositide 3-kinases (PI3Ks) regulate many cellular processes and are linked to several cancers. The PI3K catalytic subunit, p110α, dimerizes with the p85 regulatory subunit, resulting in enzyme inhibition. Some oncogenic hot spots in p110α map to the ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/nsmb0807-688

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