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The fragile site (16)(q22) (1987)

Schmid, M. ; Feichtinger, W. ; Haaf, T.

Springer

Human genetics 〈Berlin〉 76 (1987), S. 365-368

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ISSN: 1432-1203

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary In the lymphocytes of heterozygous carriers of the rare autosomal fragile site (16)(q22) an exceptionally high frequency of sister chromatid exchanges was demonstrated at the induced fragile site by means of simultaneous berenil and BrdU treatment of the cultures. The rate of sister chromatid exchanges at q22 is also increased in the fragile chromosome 16 by treating the cells with BrdU alone. The possible reasons for the preferential occurrence of induced and spontaneous sister chromatid exchanges at fra (16)(q22) are discussed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00272446

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