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Mitotic asynchrony of multinucleate cells in tissue culture (1978)

Ghosh, S. ; Paweletz, N. ; Ghosh, I.

Springer

Chromosoma 65 (1978), S. 293-300

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ISSN: 1432-0886

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract A high degree of mitotic asynchrony is reported for spontaneously arising multinucleate cells of HeLa and Pt-K1, tissue culture cell lines. Neither nuclear number, nor nuclear size nor the presence or absence of nucleoli, could be directly related to the asynchronous behaviour of the cells. Suboptimal levels of nutrients led to a higher frequency of asynchrony. A partial compartmentation of the cytoplasm could be detected in some of the multinucleate cells. The compartmentation of the cytoplasm may lead to an uneven distribution of inducer and non-inducer metabolites. All these factors together may be responsible for the high degree of mitotic asynchrony.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00286409

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